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https://www.readbyqxmd.com/read/28426894/characteristics-and-course-of-enthesitis-in-a-juvenile-idiopathic-arthritis-inception-cohort
#1
Dax G Rumsey, Jaime Guzman, Alan M Rosenberg, Adam M Huber, Rosie Scuccimarri, Natalie J Shiff, Alessandra Bruns, Brian M Feldman, Dean T Eurich
Objective To describe the prevalence, associated characteristics, and course of enthesitis in a juvenile idiopathic arthritis (JIA) inception cohort. Methods Canadian children newly diagnosed with JIA between 2005 and 2010 were categorized using ILAR criteria at the 6-month visit and followed in the ReACCh-Out cohort for up to 5 years. The presence of entheseal tenderness on examination at 33 sites shown on a homunculus was recorded at 0, 6, 12, 18, 24, 36, 48 and 60 months after enrolment. Enthesitis was defined as entheseal tenderness at more than one site or on more than one occasion...
April 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28414677/a-rare-case-of-tropical-pyomysitis-acquired-on-vacation-in-a-healthy-male
#2
K Poole, T Tran
INTRODUCTION: Pyomyositis has traditionally been considered a tropical disease. Increasing prevalence has been observed in more northern climates, especially with HIV, immunosuppression, and IV drug abuse as predisposing factors. Pyomyositis has the tendency to mimic other conditions, such as muscle contusion, necrotizing fasciitis, or septic arthritis. The rarity of this disease and non-specificity of its symptoms often lead to delay in appropriate diagnosis and treatment. CASE: 24-year-old man, seen 2 days prior in orthopedics clinic and the Emergency Department for persistent gluteal pain thought to be due to right-sided sciatica, was admitted following worsening pain, diffuse generalized weakness with polyarthralgias and myalgias These symptoms were associated with night sweats, shaking chills, and difficulty walking...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28408930/a-case-of-initially-undiagnosed-chikungunya-arthritis-developing-into-chronic-phase-in-a-nonendemic-area
#3
Pui Shan Julia Chan, Moon Ho Leung
This case report described a 40-year-old lady presented with fever, headache, arthralgia, myalgia, and impaired liver function after returning from the Philippines. Chikungunya virus (CHIKV) and dengue serology were negative. Eight weeks after initial presentation, she experienced inflammatory polyarthritis mimic rheumatoid arthritis. This time CHIKV-IgM was detected, together with a >4-fold rise of CHIKV-polyvalent-antibody titre. The first CHIKV-IgM negative sample was reexamined and was CHIKV-PCR positive...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28408063/-cutaneous-lesions-and-polyarthritis
#4
C Guillochon-Petitcuenot, H Herrscher, C Sachs, D De Briel, M Schutte, L Spielmann, P Moreau, L Messer
No abstract text is available yet for this article.
April 10, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28389347/patho-bacteriological-investigation-of-an-outbreak-of-mycoplasma-bovis-infection-in-calves-emerging-health-assault
#5
Fazal Mahmood, Ahrar Khan, Riaz Hussain, Imtiaz Ahmad Khan, Rao Zahid Abbas, Hafiz Muhammad Ali, Muhammad Younus
Mycoplasma bovis (M. bovis) is an important bacterium, causing severe respiratory infection, and arthritis in dairy animals worldwide. This study is based on 50 suckling calves among which 15 showed respiratory distress, lameness and swollen joints and died later. M. bovis was isolated and identified from all dead (n = 15) and live (17.14%; 06 out of 35) calves on the basis on bacteriological examination. In morbid calves, the carpus and stifle joints were severely affected, while necropsy revealed multiple well-circumscribed calcified abscesses and caseous exudates in cranio-ventral and diaphragmatic lobes of lungs...
April 4, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28386137/measurement-of-blood-calprotectin-mrp-8-mrp-14-levels-in-patients-with-juvenile-idiopathic-arthritis
#6
Jaryna Bojko
OBJECTIVES: The aim of the investigation was to compare blood calprotectin (MRP8/14, S100A 8/9) levels in patients with systemic-onset, polyarticular, RF-negative and oligoarticular subtypes of juvenile idiopathic arthritis (JIA), and to explore links between blood calprotectin levels and clinical and laboratory markers of JIA activity. MATERIAL AND METHODS: Measurement of calprotectin in blood serum was performed in 160 patients with JIA followed up at Lviv Regional Council Public Institution "Western-Ukrainian Specialised Children's Medical Centre"...
2017: Reumatologia
https://www.readbyqxmd.com/read/28381237/poncet-s-disease-two-case-reports
#7
Fatima Adhi, Rabia Hasan, Mehreen Adhi, Syed Ali Hamid, Nousheen Iqbal, Javaid A Khan
BACKGROUND: One of the rare presentations of active pulmonary or even extrapulmonary tuberculosis is polyarthropathy which is the involvement of multiple large and small joints in the body; a reactive constellation known as Poncet's disease. This may sometimes be the sole manifestation of the disease before more obvious features develop. The pain experienced during polyarthritis can be crippling thereby limiting the mobility and activities of patients. Polyarthritis as a symptom of active tuberculosis can be easily misinterpreted for more common causes of polyarthritis such as rheumatological diseases that present similarly...
April 6, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28379857/postsurgical-pyoderma-gangrenosum-versus-necrotizing-fasciitis-can-we-spot-the-difference
#8
Leila L Touil, Dilnath A R Gurusinghe, Amir Sadri, Ahmed El-Gawad, Fahmy S Fahmy
BACKGROUND: Pyoderma gangrenosum is a rare noninfectious cutaneous disease characterized by expanding areas of skin ulceration around necrotic centers with purulent debris. Exceptionally, it can be precipitated by surgery alone, and this entity has been described as postsurgical pyoderma gangrenosum (PSPG). Cases of PSPG in the literature are rare. METHODS: We performed a retrospective review of the current literature on PSPG and highlight some observed differences between these conditions...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28376065/chikungunya-virus-and-autoimmunity
#9
Amir Tanay
PURPOSE OF REVIEW: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. Fever, rash and severe arthralgia are the hallmarks of chikungunya fever (CHIKF), the disease caused by this virus. The acute course of the disease usually lasts few weeks to months. Chronic, relapsing or persistent arthralgia and arthritis have been described mimicking rheumatoid arthritis (RA), requiring immunosuppressive drugs.The purpose of this review is to characterize both the chronic clinical course of CHIKF-associated arthritis and the immunological pathogenic mechanisms involved...
April 1, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28373868/morin-attenuates-streptococcus-suis-pathogenicity-in-mice-by-neutralizing-suilysin-activity
#10
Gen Li, Gejin Lu, Zhimin Qi, Hongen Li, Lin Wang, Yanhui Wang, Bowen Liu, Xiaodi Niu, Xuming Deng, Jianfeng Wang
Streptococcus suis, a Gram-positive pathogen, is widely recognized as an important agent of swine infection, and it is also known to cause a variety of zoonoses, such as meningitis, polyarthritis and pneumonia. Suilysin (SLY), an extracellular pore-forming toxin that belongs to the cholesterol-dependent cytolysin family, is an essential virulence factor of S. suis capsular type 2 (SS2). Here, we found that morin hydrate (morin), a natural flavonoid that lacks anti-SS2 activity, inhibits the hemolytic activity of SLY, protects J774 cells from SS2-induced injury and protects mice from SS2 infection...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28371810/characteristics-of-the-musculoskeletal-symptoms-observed-among-survivors-of-ebola-virus-disease-in-the-postebogui-cohort-in-guinea
#11
Yves-Marie Pers, Mamadou Saliou Sow, Bernard Taverne, Laura March, Suzanne Izard, Jean François Étard, Moumié Barry, Abdoulaye Touré, Eric Delaporte
Objective.: Previous studies show that arthralgia is the most common symptom experienced by Ebola virus disease (EVD) survivors. Nevertheless, specific analyses of rheumatological sequelea are still lacking. Methods.: The Postebogui study is a prospective, multicentre cohort aiming to evaluate the long-term outcomes of EVD survivors infected during the 2014-15 outbreak in Guinea. Of the 216 participants enrolled in the study in October 2015, 44 patients with arthralgia/myalgia underwent a physical examination by a rheumatologist (the Eborheum cohort)...
March 22, 2017: Rheumatology
https://www.readbyqxmd.com/read/28358242/a-12-year-retrospective-review-of-bullous-systemic-lupus-erythematosus-in-cutaneous-and-systemic-lupus-erythematosus-patients
#12
K Chanprapaph, S Sawatwarakul, V Vachiramon
Objective The aim of this study was to investigate the clinical features, laboratory findings, systemic manifestations, treatment and outcome of patients with bullous systemic lupus erythematosus in a tertiary care center in Thailand. Methods We performed a retrospective review from 2002 to 2014 of all patients who fulfilled the diagnostic criteria for bullous systemic lupus erythematosus to evaluate for the clinical characteristics, extracutaneous involvement, histopathologic features, immunofluorescence pattern, serological abnormalities, internal organ involvement, treatments and outcome...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28348765/progressive-disseminated-histoplasmosis-mimicking-a-flare-of-systemic-lupus-erythematosus-a-european-case-report
#13
M L M van Doorn-Schepens, E J Peters, R M van Vugt, J I van der Spoel, K van Dijk
INTRODUCTION: Diagnosing progressive disseminated histoplasmosis (PDH) in patients with systemic lupus erythematosus (SLE) is diagnostically challenging. Since PDH is lethal when untreated, awareness of this infection in patients with SLE is of utmost importance. To the best of our knowledge, this is the first description of a case of PDH in a patient with SLE in Europe. CASE PRESENTATION: A 56-year-old woman of Surinamese descent with a history of SLE, presented with fever and polyarthritis...
August 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28329487/apremilast-for-the-treatment-of-psoriatic-arthritis
#14
Brent C Martin, Logan W Thomas, Francis J Dann
Psoriatic arthritis (PsA) is a chronic inflammatoryarthropathy that affects joints and entheses andis associated with psoriasis (PsO). There are fiveclinical patterns of PsA: symmetrical polyarthritis,distal interphalangeal arthropathy, asymmetricaloligoarthritis, arthritis mutilans, and spondylitis, withor without sacroiliitis. Concerning PsA, the goals oftherapy are to control inflammation, prevent articulardamage, and reduce discomfort in the affected joints.Although there are many therapeutic options forthe treatment of PsAs, physicians most often beginwith nonsteroidal anti-inflammatory drugs (NSAIDs)for mild disease...
February 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28322700/increased-proinflammatory-cytokine-levels-in-prolonged-arthralgia-in-ross-river-virus-infection
#15
Dennis Tappe, José Vicente Pérez-Girón, Sergio Gómez-Medina, Stephan Günther, César Muñoz-Fontela, Jonas Schmidt-Chanasit
Ross River virus, a mosquitoborne alphavirus, causes epidemic polyarthritis in Australia and the Pacific region. We analyzed serum cytokine, chemokine, and growth factor levels in travelers returning to Germany from Australia. Serum samples showed elevated concentrations in the acute phase of the illness and, more pronounced, in the long-lasting convalescent phase.
April 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28320056/health-related-quality-of-life-in-an-inception-cohort-of-children-with-juvenile-idiopathic-arthritis-a-longitudinal-analysis
#16
Kiem Oen, Jaime Guzman, Brenden Dufault, Lori B Tucker, Natalie J Shiff, Karen Watanabe Duffy, Jennifer J Y Lee, Brian M Feldman, Roberta A Berard, Paul Dancey, Adam M Huber, Rosie Scuccimarri, David A Cabral, Kimberly A Morishita, Suzanne E Ramsey, Alan M Rosenberg, Gilles Boire, Susanne M Benseler, Bianca Lang, Kristin Houghton, Paivi M Miettunen, Gaëlle Chédeville, Deborah M Levy, Alessandra Bruns, Heinrike Schmeling, Elie Haddad, Rae S M Yeung, Ciarán M Duffy
OBJECTIVES: To describe changes in health-related quality of life (HRQL) over time in children with juvenile idiopathic arthritis (JIA), relative to other outcomes; to identify predictors of unfavourable HRQL trajectories. METHODS: Children with JIA in the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) cohort were included. The Juvenile Arthritis Quality of Life Questionnaire (JAQQ, a standardized instrument), health-related Quality of My Life (HRQoML, an instrument based on personal valuations) and JIA core variables were completed serially...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28295452/presumed-lupus-erythematosus-cells-identified-in-bronchoalveolar-lavage-fluid-from-a-mexican-hairless-dog
#17
Laura J Black, Ashley C Hechler, Maura E Duffy, Sarah S K Beatty
A neutered male Mexican Hairless dog was presented for generalized weight loss and weakness. Initial laboratory testing and diagnostic imaging revealed thrombocytopenia and an interstitial to miliary lung pattern affecting all lung fields. Mild joint effusion was found on physical examination affecting the stifle, tarsal, carpal, and elbow joints. Examination of synovial fluid demonstrated an inflammatory polyarthropathy in 3 joints. Cytocentrifuged and direct preparations of the bronchoalveolar lavage (BAL) fluid sample were made and cells consistent with lupus erythematosus (LE) cells and ragocytes were found...
March 13, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28263344/acute-inflammatory-polyarthritis-a-rare-presentation-of-secondary-syphilis
#18
Xu Cong Ruan, Joel Hl Lim, Hong Liang Tey
No abstract text is available yet for this article.
February 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28255484/surgical-management-of-multijoint-septic-arthritis-due-to-rat-bite-fever-in-a-pediatric-patient-a-case-study
#19
Adam M Wegner, Nicole Look, Brian M Haus
In the United States, rat-bite fever is a rare systemic illness principally caused by Streptobacillus moniliformis, an organism found in the nasopharyngeal flora of rodents. Infection through direct exposure to rat excreta such as saliva, urine, or feces can lead to fever, rash, and an asymmetric migratory polyarthritis. As rodents are becoming more popular as pets, more pediatric cases are being documented. We report a pediatric case of delayed onset septic arthritis in the left wrist and right knee due to S...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28255335/the-clinical-characteristics-of-sarcoid-arthropathy-based-on-a-prospective-cohort-study
#20
Senol Kobak, Fidan Sever, Ozan Usluer, Tuncay Goksel, Mehmet Orman
BACKGROUND: Sarcoidosis is known as a Th1-mediated disease, which can mimic many primary rheumatologic diseases or sometimes co-exist with them. Clinical characteristics of sarcoid arthropathy are not well described and the studies reported in the literature so far are mostly based on data from referrals. The aim of this study was to evaluate the incidence and clinical characteristics of sarcoid arthropathy. METHODS: All our patients were prospectively evaluated in our rheumatology outpatient center from 2011 to 2015...
December 2016: Therapeutic Advances in Musculoskeletal Disease
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