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https://www.readbyqxmd.com/read/29779410/personalized-charts-for-the-fetal-corpus-callosum-length
#1
Abraham Tsur, Boaz Weisz, Orgad Rosenblat, Daniel Shai, Estela Derazne, David K Stevenson, Reuven Achiron, Eldad Katorza
OBJECTIVE: To personally customize the antenatal ultrasound charts for the fetal corpus callosum (CC) length. METHODS: A retrospective analysis of fetal neuro-sonography scans. Cases were grouped as normal neuro-sonographic evaluation (normal) or as high risk and suspected brain anomaly (abnormal). The normal group was subcategorized according to Cignini's CC length charts. Data of fetuses with a CC length between the 5th-95th percentile served for creating new charts, describing the ratio of the CC length to the major biometric parameters as a function of gestational age (GA)...
May 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29715700/lung-ultrasound-findings-in-congenital-pulmonary-airway-malformation
#2
Nadya Yousef, Mostafa Mokhtari, Philippe Durand, Francesco Raimondi, Fiorella Migliaro, Alexandra Letourneau, Pierre Tissières, Daniele De Luca
BACKGROUND AND OBJECTIVE:  Congenital pulmonary airway malformation (CPAM) is a group of rare congenital malformations of the lung and airways. Lung ultrasound (LU) is increasingly used to diagnose neonatal respiratory diseases since it is quick, easy to learn, and radiation-free, but no formal data exist for congenital lung malformations. We aimed to describe LU findings in CPAM neonates needing neonatal intensive care unit (NICU) admission and to compare them with a control population...
May 1, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29675495/maternal-history-and-uterine-artery-wave-form-in-the-prediction-of-early-onset-and-late-onset-preeclampsia-a-cohort-study
#3
Nidhi Sharma, Krishnamurthy Jayashree, Kulasekaran Nadhamuni
Background: Pregnancy induced hypertension (PIH) is a significant cause of maternal morbidity and mortality. Pregnancy-induced-hypertension can be prevented by identification of prenatal and antenatal factors. The uterine artery Doppler waveform transforms into a high flow with low resistance at 22-24 wk. Objective: To study the maternal risk factors and uterine artery Doppler waveform in singleton mid-trimester pregnancy and predict the occurrence of pregnancy-induced hypertension ...
February 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29660172/predictive-accuracy-of-the-southwest-thames-obstetric-research-collaborative-stork-chorionicity-specific-twin-growth-charts-for-stillbirth-a-validation-study
#4
Erkan Kalafat, Mercedes Sebghati, Basky Thilaganathan, Asma Khalil
OBJECTIVE: Twin pregnancy is associated with 2-3 fold increased risk of stillbirth compared to singletons. Despite the fact that the growth pattern has been shown to differ in twins compared to singletons, it is controversial whether twin-specific growth charts should be routinely used. A major goal of prenatal ultrasound is to identify fetuses suffering from growth restriction at risk of stillbirth. The main aim of this study was to compare the performance of chorionicity-specific twin charts with singleton charts, both customized and non-customized, in the antenatal prediction of small-for-gestational age (SGA) stillborn and liveborn fetuses...
April 16, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29622834/two-cases-of-pentalogy-of-cantrell-diagnosed-antenatally-at-korle-bu-teaching-hospital-accra
#5
Alim Swarray-Deen, Joseph D Seffah, Deliverance A Antwi-Agyei
Pentalogy of Cantrell is a rare congenital malformation syndrome that may be associated with other congenital anomalies. The syndrome is said to affect males and females in equal numbers and the prognosis is generally poor. We report two cases of Cantrell's Pentalogy diagnosed antenatally at the Korle Bu teaching Hospital. The 2 cases described in this report demonstrate the complete and incomplete variant of the syndrome. The cases were referred as an omphalocoele and a detailed anomaly scan confirmed the diagnosis of Pentalogy of Cantrell...
December 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/29573501/first-trimester-and-combined-first-and-second-trimester-prediction-of-small-for-gestational-age-and-fetuses-with-late-growth-restriction
#6
Alexandros Sotiriadis, Francesc Figueras, Makarios Eleftheriades, George K Papaioannou, Georgios Chorozoglou, Konstantinos Dinas, Nikolaos Papantoniou
AIM: To develop a first-trimester or combined first- and second-trimester screening algorithm for the prediction of small-for-gestational age (SGA) and late growth-restriction (FGR). METHODS: This was a retrospective study of pregnant women with singleton pregnancy, who attended routine first- second- and third-trimester ultrasound scan. Late FGR was defined, at ≥32 weeks in the absence of congenital anomalies as, either (a) estimated fetal weight (EFW) or birthweight (BW) <3rd centile , OR (b) EFW<10th centile and either uterine artery mean PI >95th centile or cerebroplacental ratio (CPR) <5th centile...
March 24, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29456581/antenatal-diagnosis-of-total-anomalous-pulmonary-venous-connection-in-functional-single-ventricle-hearts-outcomes-over-13-year-period
#7
Precylia Fernandes, Lito Mantagou, Ram Ramaraj, Umber Agarwal, Joyce Su Ling Lim
Introduction: A functionally single cardiac ventricle seen on foetal ultrasound scan carries a guarded prognosis. The antenatal diagnosis of anomalous pulmonary venous connection (APVC) remains challenging, if there is no associated structural cardiac abnormality. Antenatally, a combination of complex cardiac anomaly with suspected isomerism should raise the possibility of associated total anomalous pulmonary venous connection (TAPVC). There needs to be a high index of suspicion for TAPVC, in functional single ventricle and suspected isomerism, as this carries a very grim outcome postnatally...
February 2018: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29437711/bilateral-testicular-torsion-in-a-36-week-neonate
#8
Michael J H Clarke, Samuel Crocker, David G Bartle, John Apsey
A male neonate born after uncomplicated vaginal delivery at 36 weeks' gestation was noted to have large and firm testicles bilaterally on routine examination. A testicular ultrasound scan was subsequently organised that showed detailed appearances consistent with bilateral testicular torsion. This was thought to have taken place antenatally and as such was unfortunately not suitable for intervention. The patient was therefore managed conservatively with the testicles left to involute naturally. He was started on testosterone replacement therapy after follow-up when gonadotrophin levels were found to be raised and testosterone low (suggesting absent testicular function) and will be closely followed up regarding his future development which is normal to this point...
February 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29409551/impact-of-prenatal-diagnosis-on-the-management-and-early-outcome-of-critical-duct-dependent-cardiac-lesions
#9
Varsha Thakur, Nathalie Dutil, Steven M Schwartz, Edgar Jaeggi
OBJECTIVE: The objective of this study was to compare the preoperative management and outcome of neonates with duct-dependent critical CHD with fetal versus postnatal diagnosis. METHODS: Patients referred with CHD to our centre from January 1, 2009 to December 31, 2010 were enrolled prospectively. Live births with a critical form of CHD, a gestational age ⩾36 weeks and a weight ⩾2 kg at birth, and the intention-to-treat were included in this sub-study. Excluded were neonates with lethal non-cardiac and/or genetic anomalies...
April 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29401400/cord-blood-metabolic-signatures-of-birth-weight-a-population-based-study
#10
Oliver Robinson, Pekka Keski-Rahkonen, Leda Chatzi, Manolis Kogevinas, Tim Nawrot, Costanza Pizzi, Michelle Plusquin, Lorenzo Richiardi, Nivonirina Robinot, Jordi Sunyer, Roel Vermeulen, Martine Vrijheid, Paolo Vineis, Augustin Scalbert, Marc Chadeau-Hyam
Birth weight is an important indicator of maternal and fetal health and a predictor of health in later life. However, the determinants of variance in birth weight are still poorly understood. We aimed to identify the biological pathways, which may be perturbed by environmental exposures, that are important in determining birth weight. We applied untargeted mass-spectrometry-based metabolomics to 481 cord blood samples collected at delivery in four birth cohorts from across Europe: ENVIRONAGE (Belgium), INMA (Spain), Piccolipiu (Italy), and Rhea (Greece)...
March 2, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29386918/bilateral-total-retinal-detachment-at-birth-a-case-report-of-walker-warburg-syndrome
#11
Navid Hakim, Cristina Soare, Jamil Hakim
Walker-Warburg syndrome (WWS) is a disorder characterized by ocular and brain malformations, and congenital muscular dystrophy. Retinal malformations are common in WWS; however, bilateral retinal detachment is a rare occurrence. We present a case of a newborn baby delivered at 36+3 weeks, who was the first living child of consanguineous parents of Turkish origin. On antenatal anomaly scans, the fetus had hydrocephalus that had increased throughout pregnancy, and a diagnosis of hydrancephaly was made at 36 weeks of gestation...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29386348/first-trimester-fetal-size-and-prescribed-asthma-medication-at-15-years-of-age
#12
Steve Turner, Shona Fielding, Graham Devereux
There is increasing evidence that antenatal factors predispose to childhood asthma. We tested the hypothesis that reduced first trimester fetal size is associated with increased risk for asthma at 15 years of age.Fetal size in the first and second trimester was ascertained by ultrasound scan. The primary outcome of being dispensed one or more asthma medications by the family doctor in the year before the 15th birthday was determined from routinely acquired dispensing data.Dispensing data were available for 1699 (88% of the original cohort) participants at 15 years of age and questionnaire data for 750 (39%)...
February 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29378980/the-prevalence-of-osteoporosis-among-antenatal-clinic-attendees-in-a-rural-mission-hospital-in-south-east-nigeria
#13
P O Ezeonu, U M Agwu, L O Ajah, I B O Dimejesi, L U Ogbonnaya, O U J Umeora, R C Onoh
INTRODUCTION: Osteoporosis is a global public health problem characterized by reduction of bone mineral density (BMD). This study aimed to assess the prevalence of osteoporosis among antenatal clinic attendees in a rural Southeastern hospital. MATERIAL AND METHODS: This was a cross-sectional study of booking Antenatal Clinic Attendees at Mile 4 Catholic Hospital, Abakaliki, between October 2014 and February 2015. The study participants were selected through systematic random sampling...
December 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29341510/maternity-ultrasound-in-the-republic-of-ireland-2016-a-review
#14
D Hayes-Ryan, K McNamara, N Russell, L Kenny, K O'Donoghue
Antenatal ultrasound, comprising of a dating ultrasound in the late first trimester followed by a fetal anomaly scan, is a recognised and necessary component of good antenatal care. We conducted a telephone survey of all 19 obstetric units to ascertain the status of maternity ultrasound provision in Ireland. Fetal anomaly ultrasound is offered universally to all women in 7/19 (37%) units, selectively to some women in 7/19 (37%) units and not offered at all in the remaining 5/19 (26%) units. Overall ? 41,700 (64%) women receive a fetal anomaly ultrasound nationally...
August 8, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/29330548/shox-haploinsufficiency-presenting-with-isolated-short-long-bones-in-the-second-and-third-trimester
#15
Shwetha Ramachandrappa, Abhijit Kulkarni, Hina Gandhi, Cheryl Ellis, Renata Hutt, Lesley Roberts, Rosol Hamid, Aris Papageorghiou, Sahar Mansour
Haploinsufficiency of the transcription factor short stature homeobox (SHOX) manifests as a spectrum of clinical phenotypes, ranging from disproportionate short stature and Madelung deformity to isolated short stature. Here, we describe five infants with molecularly confirmed diagnoses of SHOX haploinsufficiency who presented in utero with short long bones during routine antenatal scanning from as early as 19 weeks gestation. Other foetal growth parameters were normal. The molecular basis of SHOX haploinsufficiency was distinct in each case...
March 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29330267/case-of-acute-severe-postpartum-urinary-incontinence-an-extravesical-subsphincteric-prolapsed-ureterocoele
#16
Jai H Seth, Roger Walker
A 32-year-old woman presents to outpatients 10 days postpartum, with symptoms of an intermittent vaginal lump and urinary incontinence. Vaginal examination revealed no demonstrable prolapse or stress incontinence. A swelling in the bladder was noted during an antenatal scan suggesting a ureterocoele. She was referred for pelvic floor physiotherapy in the first instance. Forty-eight hours later, she represented to casualty with discomforting vaginal lump symptoms and continuous urinary incontinence. At this stage on vaginal inspection, there was an evident dusky lump emerging from the urethra with continuous incontinence...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29223928/are-there-risk-factors-for-false-positive-malformation-diagnoses-on-obstetric-ultrasound-a-nested-case-control-study
#17
A Debost-Legrand, I Perthus, O Rivière, D Gallot, D Lémery, F Vendittelli
INTRODUCTION: In a population-based study, we found an overall false-positive rate of 8.8% for the second and third trimester ultrasounds. Although numerous studies have been performed to examine factors which lead to false negatives, the same is not true for the factors associated with false positives. The principal objective of this study was to look for risk factors for false-positive diagnoses of fetal malformations on obstetric ultrasound scans. MATERIAL AND METHODS: In this nested case-control study, the case infants were those whose mother had a false-positive antenatal ultrasound diagnosis of a malformation during the second or third trimester (ultrasound false-positives) and who were live - or stillborn in Auvergne in 2006-2010...
March 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29201520/transurethral-incision-of-ureteroceles-in-paediatric-age-group
#18
Hemanshi Shah, Charu Tiwari, Neha Sisodiya Shenoy, Pankaj Dwivedi, Suraj Gandhi
Objective: Ureteroceles are a great clinical challenge because of variations in anatomy and clinical presentations. We present our experience with primary transurethral incision of ureteroceles in children. Material and methods: Data of thirteen children managed for ureterocele from 2009 to 2016 was retrospectively analyzed with respect to age, sex, clinical presentation and symptomatology, type and localization of ureterocele, investigations, surgical management and follow-up...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29175169/outcome-of-pregnancy-with-new-onset-proteinuria-and-progression-to-pre-eclampsia-a-retrospective-analysis
#19
Wai Hang Chung, William Wing Kee To
OBJECTIVE: To examine maternal and neonatal outcomes of gestational proteinuria, and to identify maternal characteristics for progression to pre-eclampsia. STUDY DESIGN: Retrospective cohort. Included all pregnant women who delivered between Jan 2014-Feb 2017 with new onset proteinuria in a single obstetric unit. Demographic, maternal and neonatal outcomes were compared. RESULTS: Eighteen (25%) out of 73 women with new onset gestational proteinuria developed pre-eclampsia...
November 21, 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29162956/risk-assessment-at-11-14-week-antenatal-visit-a-tertiary-referral-center-experience-from-south-india
#20
Anusha Vellamkondu, Akhila Vasudeva, Rajeshwari G Bhat, Asha Kamath, Sapna V Amin, Lavanya Rai, Pratap Kumar
Background: Present study carried out in a tertiary referral hospital in South India attempts to determine the predictive value of integrated screening at 11-14-week antenatal visit. Objectives: To determine the detection rate of fetal abnormalities at 11-14 weeks and also to predict the placental dysfunction disorders based on early integrated evaluation. Method: Integrated screening performed on 440 women between 11 and 14 weeks, including detailed maternal history [medical history, bad obstetric history (BOH)], body mass index (BMI), mean arterial pressure (MAP), detailed ultrasound and maternal serum biochemistry as part of combined first-trimester screening for aneuploidy...
December 2017: Journal of Obstetrics and Gynaecology of India
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