Ruth Namazzi, Robert O Opoka, Andrea L Conroy, Dibyadyuti Datta, Abner Tagoola, Caitlin Bond, Michael J Goings, Moon-Suhn Ryu, Sarah E Cusick, Nancy F Krebs, Jeong Hoon Jang, Wanzhu F Tu, Russell E Ware, Chandy C John
Data from small clinical trials in the USA and India suggest zinc supplementation reduces infection in adolescents and adults with sickle cell anemia (SCA), but no studies of zinc supplementation for infection prevention have been conducted in young children with SCA living in Africa, who have higher infection rates. We conducted a randomized double-blind placebo-controlled trial to assess the effectiveness of zinc supplementation for prevention of severe or invasive infections in Ugandan children 1.00-4.99 years with SCA...
February 3, 2023: Blood Advances