Camila Folle, Elena Sánchez-López, Mireia Mallandrich, Natalia Díaz-Garrido, Joaquim Suñer-Carbó, Lyda Halbaut, Paulina Carvajal-Vidal, Ana M Marqués, Marta Espina, Josefa Badia, Laura Baldoma, Maria Luisa García, Ana Cristina Calpena
Acne constitutes one of the most prevalent skin disorders affecting both skin and mental health of patients. However, no cure has been developed so far. In this area, Thymol constitutes a potential candidate since it is able to restore the healthy microbiota of the skin. However, its permeation properties cause its fast elimination and, to avoid this problem, thymol has been loaded into nanostructured lipid carriers (TH-NLCs). Moreover, to increase the suitability of these systems for skin applications, several surface functionalization strategies of TH-NLCs had been assessed...
December 21, 2023: International Journal of Pharmaceutics