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https://www.readbyqxmd.com/read/29906773/in-vitro-investigation-of-anti-acne-properties-of-mangifera-indica-l-kernel-extract-and-its-mechanism-of-action-against-propionibacterium-acnes
#1
Worrapan Poomanee, Wantida Chaiyana, Monika Mueller, Helmut Viernstein, Watcharee Khunkitti, Pimporn Leelapornpisid
Propionibacterium acnes has been recognized as a main target for medical treatment of acne since this bacterium promotes acne inflammation by inducing upregulation of pro-inflammatory cytokines production, resulting in an accumulation of neutrophils and oxygen-free radicals produced by neutrophils within acne lesion. The aims of this study were to evaluate the biological activities of Mangifera indica kernel extracts grown in Northern Thailand (Kaew-Moragot cultivar), related to anti-acne properties including antimicrobial effect against acne-inducing bacteria together with the first elucidation of the mechanism of action against Propionibacterium acnes, anti-oxidation, and anti-inflammation...
May 17, 2018: Anaerobe
https://www.readbyqxmd.com/read/29849880/preventive-and-therapeutic-role-of-functional-ingredients-of-barley-grass-for-chronic-diseases-in-human-beings
#2
REVIEW
Yawen Zeng, Xiaoying Pu, Jiazhen Yang, Juan Du, Xiaomeng Yang, Xia Li, Ling Li, Yan Zhou, Tao Yang
Barley grass powder is the best functional food that provides nutrition and eliminates toxins from cells in human beings; however, its functional ingredients have played an important role as health benefit. In order to better cognize the preventive and therapeutic role of barley grass for chronic diseases, we carried out the systematic strategies for functional ingredients of barley grass, based on the comprehensive databases, especially the PubMed, Baidu, ISI Web of Science, and CNKI, between 2008 and 2017...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29734525/zinc-containing-compounds-for-personal-care-applications
#3
REVIEW
Michał Abendrot, Urszula Kalinowska-Lis
It is well known that zinc ions are widely used in cosmetic products. Their popularity is associated with the multifunctional profile of Zn2+ , which is classified as an essential chemical element in the human body. This review examines numerous beneficial biological properties of zinc-containing compounds and classifies the compounds used in cosmetic products according to their functionality profile: antioxidant, sunscreen, anti-inflammatory, anti-pigmentation, anti-aging, anti-acne, antimicrobial, anti-odour, cleansing or stabilising activity...
May 7, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29579959/formulation-and-characterization-of-water-in-oil-nanoemulsions-loaded-with-a%C3%A3-a%C3%A3-berry-anthocyanins-insights-of-degradation-kinetics-and-stability-evaluation-of-anthocyanins-and-nanoemulsions
#4
Cezar A S Rabelo, Noamane Taarji, Nauman Khalid, Isao Kobayashi, Mitsutoshi Nakajima, Marcos A Neves
Açaí berry is the fruit of an Amazonian palm tree and rich in anthocyanins (ACNs). Scientific studies have proven the health benefits of açaí berry and declared this fruit as "super fruit". ACNs have high antioxidant activities, but they are unstable and can easily deteriorate during food processing. In order to protect ACNs and increase their applicability, food-grade water-in-oil (W/O) emulsions were successfully formulated with different concentrations of açaí berry extracts (AEs). The formulated W/O nanoemulsions were relatively stable, with no phase separation after 30 days of storage...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29558225/bioactivity-and-pharmacological-properties-of-%C3%AE-mangostin-from-the-mangosteen-fruit-a-review
#5
REVIEW
Guoqing Chen, Yong Li, Wei Wang, Liping Deng
α-Mangostin (α-MG) is the most representative xanthone isolated from the pericarp of mangosteen, possessing extensive biological activities and pharmacological properties, considered as an antineoplastic agent, antioxidant, anti-proliferation and induces apoptosis. Areas covered: The bioactivity and pharmacological properties of α-MG are being actively investigated by various industrial and academic institutions. The bioactivities of α-MG have been summarized in several previous reviews, which were worthy of high compliment...
May 2018: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/29495650/in-vitro-antimicrobial-activity-of-gel-containing-the-herbal-ball-extract-against-propionibacterium-acnes
#6
Chutima Jantarat, Pornpak Sirathanarun, Tatsanee Chuchue, Atthaphon Konpian, Gorawit Sukkua, Prutthicha Wongprasert
The herbal ball has been used as a Thai traditional medicine for relieving many diseases including acne. However, the application process of the herbal ball in practice is complicated and time consuming. The objective of this work was to utilize an herbal ball extract to formulate a gel to reach a more favorable use of the herbal ball for acne treatment. An herbal ball consisting of Andrographis paniculata , Centella asiatica , the Benchalokawichian remedy and the stem bark powder of Hesperethusa crenulata was prepared...
February 28, 2018: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/29494704/highly-sensitive-detection-and-quantification-of-the-secreted-bacterial-benevolence-factor-roxp-using-a-capacitive-biosensor-a-possible-early-detection-system-for-oxidative-skin-diseases
#7
Gizem Ertürk, Martin Hedström, Bo Mattiasson, Tautgirdas Ruzgas, Rolf Lood
The impact of the microbiota on our health is rapidly gaining interest. While several bacteria have been associated with disease, and others being indicated as having a probiotic effect, the individual biomolecules behind these alterations are often not known. A major problem in the study of these factors in vivo is their low abundance in complex environments. We recently identified the first secreted bacterial antioxidant protein, RoxP, from the skin commensal Propionibacterium acnes, suggesting its relevance for maintaining the redox homeostasis on the skin...
2018: PloS One
https://www.readbyqxmd.com/read/29451719/primary-sebocytes-and-sebaceous-gland-cell-lines-for-studying-sebaceous-lipogenesis-and-sebaceous-gland-diseases
#8
REVIEW
Marlon R Schneider, Christos C Zouboulis
Sebocytes, the major cell type in sebaceous glands, are differentiated epithelial cells that gradually accumulate lipids and eventually disrupt, releasing their content (sebum) in a secretory process known as holocrine secretion. Via the hair canal, sebum reaches the skin surface, where it has several known or postulated functions, including pheromonal, thermoregulatory, antimicrobial and antioxidant activities. Altered sebum secretion and/or structural sebaceous gland changes have also been involved in the pathogenesis of skin diseases, such as acne vulgaris and some forms of alopecia...
February 16, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29248772/studies-on-polar-high-speed-counter-current-chromatographic-systems-in-separation-of-amaranthine-type-betacyanins-from-celosia-species
#9
Aneta Spórna-Kucab, Angelika Milo, Agnieszka Kumorkiewicz, Sławomir Wybraniec
Betacyanins, natural plant pigments exhibiting antioxidant and chemopreventive properties, were extracted from Celosia spicata (Thouars) Spreng. inflorescences and separated by high-speed counter-current chromatography (HSCCC) in two polar solvent systems composed of: TBME - 1-BuOH - ACN - H2 O (0.7% HFBA, 2:2:1:5, v/v/v/v) (system I) and EtOH - ACN - 1-PrOH - (NH4 )2 SO4satd.soln - H2 O (0.5:0.5:0.5:1.2:1, v/v/v/v/v) (system II). The systems were used in the head-to-tail (system I) and tail-to-head (system II) mode...
January 15, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29216958/investigation-of-extracts-from-tunisian-ethnomedicinal-plants-as-antioxidants-cytotoxins-and-antimicrobials
#10
Fatma Guesmi, Ahmed Sami Ben Hadj, Ahmed Landoulsi
OBJECTIVE: To determine the medicinal potential of various plants and their parts extracted with different solvents. METHODS: The total phenolic content of acetonitrile/water (60%-40%) (ACN/W) and aqueous (W) extract fractions was determined by high-performance liquid chromatography (HPLC), and terpenic compounds were detected by gas chromatography/mass spectrometry (GC/MS). Antioxidant activity of the samples was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and β-carotene bleaching method...
November 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28915843/protective-effects-of-gaba-against-metabolic-and-reproductive-disturbances-in-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#11
Asad Ullah, Sarwat Jahan, Suhail Razak, Madeeha Pirzada, Hizb Ullah, Ali Almajwal, Naveed Rauf, Tayyaba Afsar
BACKGROUND: PCOs is a heterogeneous disorder with anovulation/oligo ovulation usually taken as oligo menorrhoea or amenorrhoea, hyperandrogenemia, hirsutism, acne, androgen alopecia and polycystic ovaries as the key diagnostic feathers. The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance. METHODS: PCOs in Adult female rat was induced by the daily gastric administration of letrozole (1 mg/kg/day) in CMC (0...
September 15, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28873693/comparison-and-screening-of-bioactive-phenolic-compounds-in-different-blueberry-cultivars-evaluation-of-anti-oxidation-and-%C3%AE-glucosidase-inhibition-effect
#12
Ying Wu, Qing Zhou, Xiao-Yong Chen, Xing Li, Yi Wang, Jiu-Liang Zhang
This study was aimed to investigate antioxidation and α-glucosidase inhibition of the bioactive compounds in three cultivars of blueberry ('Northland' (NL) from the hybrid blueberry (V. corymbosum L.×V. angustifolium Aiton), 'Britewell' (BW), and 'Gardenblue' (GB) from the rabbiteye blueberry (Vaccinium ashei Reade)). A total of eighteen anthocyanins were identified and quantified in Anthocyanins (ACNs), among which four acylated anthocyanins were exclusively found in Northland. The blueberry anthocyanin extracts (BAEs) were further measured the antioxidant activity and α-glucosidase inhibition effect...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28662006/-turmeric-not-only-spice
#13
REVIEW
Zygmunt Zdrojewicz, Marta Szyca, Ewa Popowicz, Tomasz Michalik, Bartłomiej Śmieszniak
The purpose of this article is to introduce the role of turmeric in medicine and summarize the current state of research on its applications. Turmeric (Curcuma longa) has had a wide range of uses in middle eastern and orietnal traditional medicine. Currently, however, its use has been truncated to a common cooking spice, despite numerous studies pointing to its healing properties and possible use in the treatment of many diseases. The main focus is on curcumin, a polyphenol which serves as the biologically active component of turmeric...
June 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28631890/oxidative-stress-and-psychiatric-morbidity-in-patients-with-facial-acne
#14
Sara M Awad, Hanan Morsy, Ayat A Sayed, Nahed A Mohamed, Ghada M Ezzat, Mostafa M Noaman
BACKGROUND: Acne vulgaris is a common cosmetic problem that is frequently associated with psychosocial disturbances as well as increased oxidative stress. However, oxidative stress and psychological aspects have been studied separately in acne. OBJECTIVE: To evaluate the relationships between oxidative stress, anxiety, depression, and quality of life in acne patients. METHODS: Sixty patients with facial acne and 40 age- and sex-matched healthy individuals were included in the study...
April 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28587444/assessment-of-changes-in-the-content-of-anthocyanins-phenolic-acids-and-antioxidant-property-of-saccharomyces-cerevisiae-mediated-fermented-black-rice-bran
#15
Chaiyavat Chaiyasut, Noppawat Pengkumsri, Sasithorn Sirilun, Sartjin Peerajan, Suchanat Khongtan, Bhagavathi Sundaram Sivamaruthi
Studies on phytochemical properties and bioactivities of rice bran revealed the wealth of natural complex antioxidant compounds. The composition and the properties of the rice bran get altered after fermentation by several microbes. This study was designed to optimize the black rice bran fermentation conditions for the total anthocyanin (ACN) content, total antioxidant properties, and relative activity of β-glucosidase (BGS) by Saccharomyces cerevisiae. The Box-Behnken design and response surface methodology was employed to achieve the maximum response in fermentation...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28249743/multifaceted-functions-of-the-forkhead-box-transcription-factors-foxo1-and-foxo3-in-skin
#16
REVIEW
Dimitrios Tsitsipatis, Lars-Oliver Klotz, Holger Steinbrenner
BACKGROUND: The ubiquitously expressed forkhead box, class O (FoxO) transcription factors act as signaling integrators in extensive transcriptional networks, ensuring maintenance of cell and tissue homeostasis over time and in response to environmental challenges. Proteins whose biosynthesis is controlled through FoxOs fulfil key functions in antioxidant defense, metabolism, cell cycle regulation and apoptosis. SCOPE OF REVIEW: All four mammalian FoxO isoforms (FoxO1, FoxO3, FoxO4 and FoxO6) are expressed in skin but functions have been specified only for FoxO1 and FoxO3...
May 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28208738/oral-administration-of-the-japanese-traditional-medicine-keishibukuryogan-ka-yokuinin-decreases-reactive-oxygen-metabolites-in-rat-plasma-identification-of-chemical-constituents-contributing-to-antioxidant-activity
#17
Yosuke Matsubara, Takashi Matsumoto, Kyoji Sekiguchi, Junichi Koseki, Atsushi Kaneko, Takuji Yamaguchi, Yumiko Kurihara, Hiroyuki Kobayashi
Insufficient detoxification and/or overproduction of reactive oxygen species (ROS) induce cellular and tissue damage, and generated reactive oxygen metabolites become exacerbating factors of dermatitis. Keishibukuryogan-ka-yokuinin (KBGY) is a traditional Japanese medicine prescribed to treat dermatitis such as acne vulgaris. Our aim was to verify the antioxidant properties of KBGY, and identify its active constituents by blood pharmacokinetic techniques. Chemical constituents were quantified in extracts of KBGY, crude components, and the plasma of rats treated with a single oral administration of KBGY...
February 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28194718/employing-central-composite-design-for-evaluation-of-biomass-production-by-fusarium-venenatum-in-vivo-antioxidant-and-antihyperlipidemic-properties
#18
Asha Byju Thomas, Trupti Dattatray Shetane, Ranu Goutam Singha, Rabindra K Nanda, Sushilkumar S Poddar, Ajinath Shirsat
The present study deals with the cost effective production of biomass from Fusarium venenatum using different carbon sources (cane sugar, brown sugar, malt and fructose). Optimization of selected carbon sources and seed size using Central Composite Response Surface Design (CCRSD) indicated that sucrose (1.64 g/100 mL) and seed size (10% v/v) were optimal in maximizing biomass yield (0.5602 g/100 mL, p < 0.0001) and protein yield (49.99%, p < 0.01) of Fusarium venenatum. The acetonitrile and methanolic extracts of biomass showed promising antioxidant activity (DPPH assay, 59...
September 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28036057/green-tea-and-other-tea-polyphenols-effects-on-sebum-production-and-acne-vulgaris
#19
REVIEW
Suzana Saric, Manisha Notay, Raja K Sivamani
Polyphenols are antioxidant molecules found in many foods including nuts, fruits, vegetables, chocolate, wine, and tea. Polyphenols have antimicrobial, anti-inflammatory, and antineoplastic properties. Recent studies suggest that tea polyphenols may be used for reducing sebum production in the skin and for treatment of acne vulgaris. This review examines the evidence for use of topically and orally ingested tea polyphenols against sebum production and for acne treatment and prevention. The PubMed database was searched for studies on tea polyphenols, sebum secretion, and acne vulgaris...
December 29, 2016: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/27805044/a-novel-enzyme-with-antioxidant-capacity-produced-by-the-ubiquitous-skin-colonizer-propionibacterium-acnes
#20
Maria Allhorn, Sabine Arve, Holger Brüggemann, Rolf Lood
The role of the skin microbiota in human health is poorly understood. Here, we identified and characterized a novel antioxidant enzyme produced by the skin microbiota, designated RoxP for radical oxygenase of Propionibacterium acnes. RoxP is uniquely produced by the predominant skin bacterium P. acnes, with no homologs in other bacteria; it is highly expressed and strongly secreted into culture supernatants. We show that RoxP binds heme, reduces free radicals, and can protect molecules from oxidation. Strikingly, RoxP is crucial for the survival of P...
November 2, 2016: Scientific Reports
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