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Applied Behavioral

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https://www.readbyqxmd.com/read/28227757/feasibility-study-for-the-assessment-of-cardio-respiratory-coupling-in-newborn-infants
#1
Maristella Lucchini, William P Fifer, Manuela Ferrario, Maria G Signorini, Maristella Lucchini, William P Fifer, Manuela Ferrario, Maria G Signorini, Maristella Lucchini, Maria G Signorini, William P Fifer, Manuela Ferrario
Cardio Respiratory Coupling (CRC) plays a key role during infant development. Nonetheless, mechanisms underlying it are still mostly unexplained and tools to assess it are often inadequate to understand its functioning. This study aims to evaluate the feasibility of CRC activity detection and quantification analyzing ECG and respiration of newborn healthy subjects. Cross-spectral analysis (coherence) and a novel application of a nonlinear method (Bivariate Phase Rectified Signal Averaging) were applied on 10 minutes recording from 4 subjects...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227752/multiscale-analysis-of-information-dynamics-for-linear-multivariate-processes
#2
Luca Faes, Alessandro Montalto, Sebastiano Stramaglia, Giandomenico Nollo, Daniele Marinazzo, Luca Faes, Alessandro Montalto, Sebastiano Stramaglia, Giandomenico Nollo, Daniele Marinazzo, Alessandro Montalto, Luca Faes, Sebastiano Stramaglia, Giandomenico Nollo, Daniele Marinazzo
In the study of complex physical and physiological systems represented by multivariate time series, an issue of great interest is the description of the system dynamics over a range of different temporal scales. While information-theoretic approaches to the multiscale analysis of complex dynamics are being increasingly used, the theoretical properties of the applied measures are poorly understood. This study introduces for the first time a framework for the analytical computation of information dynamics for linear multivariate stochastic processes explored at different time scales...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227621/non-contact-automatic-respiration-monitoring-in-restrained-rodents
#3
Behnaz Rezaei, Jared Lowe, Jason R Yee, Stephen Porges, Sarah Ostadabbas, Behnaz Rezaei, Jared Lowe, Jason R Yee, Stephen Porges, Sarah Ostadabbas, Sarah Ostadabbas, Jason R Yee, Stephen Porges, Jared Lowe, Behnaz Rezaei
Prairie voles are socially monogamous rodents that form social bonds similar to those seen in primates. Social behavior investigation in these species, that include studying their breathing regulation, can provide us with an invaluable psychological model to understand social and emotional functions in both animals and humans. There have been several studies associated with the respiratory pattern of these species in the state of fear-induced defense. However, non-invasive measurement methods employed so far suffer from the lack of a natural experiment environment for the rodents...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227542/biologically-inspired-multi-layered-synthetic-skin-for-tactile-feedback-in-prosthetic-limbs
#4
Luke Osborn, Harrison Nguyen, Joseph Betthauser, Rahul Kaliki, Nitish Thakor, Luke Osborn, Harrison Nguyen, Joseph Betthauser, Rahul Kaliki, Nitish Thakor, Joseph Betthauser, Luke Osborn, Nitish Thakor, Rahul Kaliki, Harrison Nguyen
The human body offers a template for many state-of-the-art prosthetic devices and sensors. In this work, we present a novel, sensorized synthetic skin that mimics the natural multi-layered nature of mechanoreceptors found in healthy glabrous skin to provide tactile information. The multi-layered sensor is made up of flexible piezoresistive textiles that act as force sensitive resistors (FSRs) to convey tactile information, which are embedded within a silicone rubber to resemble the compliant nature of human skin...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227536/a-pilot-study-on-the-neurometric-evaluation-of-effective-and-ineffective-antismoking-public-service-announcements
#5
Giulia Cartocci, Enrica Modica, Dario Rossi, Anton Giulio Maglione, Isotta Venuti, Giulia Rossi, Elena Corsi, Fabio Babiloni, Giulia Cartocci, Enrica Modica, Dario Rossi, Anton Giulio Maglione, Isotta Venuti, Giulia Rossi, Elena Corsi, Fabio Babiloni, Enrica Modica, Isotta Venuti, Giulia Rossi, Fabio Babiloni, Anton Giulio Maglione, Dario Rossi, Elena Corsi, Giulia Cartocci
Tobacco use is the leading cause of preventable death and smoking-related illness worldwide. Research has shown that antismoking advertising may help reduce this habit. Nowadays, public service announcements (PSAs) are considered "Effective" or "Ineffective" on the base of official reports concerning behavioral/attitudinal changes toward healthier patterns and health-related savings following the exposure to the PSA. In this pilot study, we described the results of the use of three neurometric indexes for the evaluation of the efficacy of a couple of antismoking PSAs in a reduced sample of voluntary participants...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227390/bio-heat-transfer-model-of-electroconvulsive-therapy-effect-of-biological-properties-on-induced-temperature-variation
#6
Marilia M de Oliveira, Paul Wen, Tony Ahfock, Marilia M de Oliveira, Paul Wen, Tony Ahfock, Paul Wen, Marilia M de Oliveira, Tony Ahfock
A realistic human head model consisting of six tissue layers was modelled to investigate the behavior of temperature profile and magnitude when applying electroconvulsive therapy stimulation and different biological properties. The thermo-electrical model was constructed with the use of bio-heat transfer equation and Laplace equation. Three different electrode montages were analyzed as well as the influence of blood perfusion, metabolic heat and electric and thermal conductivity in the scalp. Also, the effect of including the fat layer was investigated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227295/classification-of-obsessive-compulsive-disorder-from-resting-state-fmri
#7
Bhaskar Sen, Gail A Bernstein, Tingting Xu, Bryon A Mueller, Mindy W Schreiner, Kathryn R Cullen, Keshab K Parhi, Bhaskar Sen, Gail A Bernstein, Tingting Xu, Bryon A Mueller, Mindy W Schreiner, Kathryn R Cullen, Keshab K Parhi, Keshab K Parhi, Gail A Bernstein, Tingting Xu, Kathryn R Cullen, Bryon A Mueller, Mindy W Schreiner, Bhaskar Sen
Obssesive-compulsive disorder (OCD) is a serious mental illness that affects the overall quality of the patients' daily lives. Accurate diagnosis of this disorder is a primary step towards effective treatment. Diagnosing OCD is a lengthy procedure that involves interviews, symptom rating scales and behavioral observation as well as the experience of a clinician. Discovering signal processing and network based biomarkers from functional magnetic resonance scans of patients may greatly assist the clinicians in their diagnostic assessments...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227229/ensemble-statistical-and-subspace-clustering-model-for-analysis-of-autism-spectrum-disorder-phenotypes
#8
Khalid Al-Jabery, Tayo Obafemi-Ajayi, Gayla R Olbricht, T Nicole Takahashi, Stephen Kanne, Donald Wunsch, Khalid Al-Jabery, Tayo Obafemi-Ajayi, Gayla R Olbricht, T Nicole Takahashi, Stephen Kanne, Donald Wunsch, Donald Wunsch, Tayo Obafemi-Ajayi, Khalid Al-Jabery, Stephen Kanne, Gayla R Olbricht, T Nicole Takahashi
Heterogeneity in Autism Spectrum Disorder (ASD) is complex including variability in behavioral phenotype as well as clinical, physiologic, and pathologic parameters. The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) now diagnoses ASD using a 2-dimensional model based social communication deficits and fixated interests and repetitive behaviors. Sorting out heterogeneity is crucial for study of etiology, diagnosis, treatment and prognosis. In this paper, we present an ensemble model for analyzing ASD phenotypes using several machine learning techniques and a k-dimensional subspace clustering algorithm...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226937/design-of-a-bio-inspired-pneumatic-artificial-muscle-with-self-contained-sensing
#9
Onder Erin, Nishant Pol, Luis Valle, Yong-Lae Park, Onder Erin, Nishant Pol, Luis Valle, Yong-Lae Park, Nishant Pol, Luis Valle, Onder Erin, Yong-Lae Park
Pneumatic artificial muscles (PAMs) are one of the most famous linear actuators in bio-inspired robotics. They can generate relatively high linear force considering their form factors and weights. Furthermore, PAMs are inexpensive compared with traditional electromagnetic actuators (e.g. DC motors) and also inherently light and compliant. In robotics applications, however, they typically require external sensing mechanisms due to their nonlinear behaviors, which may make the entire mechanical system bulky and complicated, limiting their use in simple systems...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226890/stability-of-the-microdroplets-for-portable-biosensor
#10
Yusuke Izawa, Toshihisa Osaki, Koki Kamiya, Satoshi Fujii, Norihisa Miki, Shoji Takeuchi, Yusuke Izawa, Toshihisa Osaki, Koki Kamiya, Satoshi Fujii, Norihisa Miki, Shoji Takeuchi, Koki Kamiya, Satoshi Fujii, Norihisa Miki, Shoji Takeuchi, Yusuke Izawa, Toshihisa Osaki
This paper highlights the behavior of microdroplets used for portable biosensors. Microdroplets have been applied for various Lab-on-a-chip applications, in which portability/wearable is becoming a trend word. However, the resonance (sloshing phenomena) of the microdroplets could be an issue. For example, bilayer lipid membrane, fragile characteristics due to its thickness of 5 nm, easily ruptures by jiggling. We therefore prepared various dimensions of droplets by changing the well shape, and examined the resulting waves depending on the vibration frequency between 20 and 100 Hz, including daily life frequencies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226822/hidden-markov-factor-analysis-as-a-spatiotemporal-model-for-electrocorticography
#11
Akinyinka Omigbodun, Werner K Doyle, Orrin Devinsky, Daniel Friedman, Thomas Thesen, Vikash Gilja, Akinyinka Omigbodun, Werner K Doyle, Orrin Devinsky, Daniel Friedman, Thomas Thesen, Vikash Gilja, Akinyinka Omigbodun, Thomas Thesen, Vikash Gilja, Werner K Doyle, Orrin Devinsky, Daniel Friedman
We present a new approach to extracting low-dimensional neural trajectories that summarize the electrocorticographic (ECoG) signals recorded with high-channel-count electrode arrays implanted subdurally. In our approach, Hidden-Markov Factor Analysis (HMFA), a finite set of factor analyzers are used to model the relationship between the high-dimensional ECoG neural space and a low-dimensional latent neural space; the factor analyzers at different time points are in turn linked together with a hidden Markov model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226799/an-audiovisual-bci-system-for-assisting-clinical-communication-assessment-in-patients-with-disorders-of-consciousness-a-case-study
#12
Fei Wang, Yanbin He, Jun Qu, Qiuyou Xie, Qing Lin, Xiaoxiao Ni, Yan Chen, Ronghao Yu, Chin-Teng Lin, Yuanqing Li, Fei Wang, Yanbin He, Jun Qu, Qiuyou Xie, Qing Lin, Xiaoxiao Ni, Yan Chen, Ronghao Yu, Chin-Teng Lin, Yuanqing Li, Chin-Teng Lin, Fei Wang, Ronghao Yu, Jun Qu, Yan Chen, Yanbin He, Qiuyou Xie, Yuanqing Li, Xiaoxiao Ni, Qing Lin
The JFK Coma Recovery Scale-Revised (JFK CRS-R), a behavioral scale, is often used for clinical assessments of patients with disorders of consciousness (DOC), such as patients in a vegetative state. However, there has been a high rate of clinical misdiagnosis with the JFK CRS-R because patients with severe brain injures cannot provide sufficient behavioral responses. It is particularly difficult to evaluate the communication function in DOC patients using the JFK CRS-R because a higher level of behavioral responses is needed for communication assessments than for many other assessments, such as an auditory startle assessment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226720/comparison-of-viscoelastic-property-characterization-of-plastisol-phantoms-with-magnetic-resonance-elastography-and-high-frequency-rheometry
#13
P M Lefebvre, K Tse Ve Koon, E Brusseau, S Nicolle, J-F Palieme, S A Lambert, D Grenier, P M Lefebvre, K Tse Ve Koon, E Brusseau, S Nicolle, J-F Palieme, S A Lambert, D Grenier, P M Lefebvre, E Brusseau, S Nicolle, D Grenier, S A Lambert
This study aims at evaluating Magnetic Resonance Elastography (MRE) as a reliable technique for the characterization of viscoelastic properties of soft tissues. Three phantoms with different concentrations of plastisol and softener were prepared in order to mechanically mimic a broad panel of healthy and pathological soft tissues. Once placed in a MRI device, each sample was excited by a homemade external driver, inducing shear waves within the medium. The storage (G') and loss (G") moduli of each phantom were then reconstructed from MRE acquisitions over a frequency range from 300 to 1,000 Hz, by applying a 2D Helmholtz inversion algorithm...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226701/an-image-resolution-perspective-on-functional-activity-mapping
#14
Keith Dillon, Yu-Ping Wang, Keith Dillon, Yu-Ping Wang, Yu-Ping Wang, Keith Dillon
In this paper we apply techniques for numerical estimation of system resolution from imaging, to the regression problem of relating biological data to phenotypes. Our approach can be viewed as an extension of Backus-Gilbert theory, which attempts to find the most concentrated estimator that may be reliably computed in an inverse problem. Applied to a regression model, we estimate a minimal combination of collinear variables that may be found in a predictor, which gives a robust multivariable estimate of the network relationships in the data...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226480/eeg-based-image-encryption-via-quantum-walks
#15
N Rawat, Y Shin, I Balasingham, N Rawat, Y Shin, I Balasingham, I Balasingham, N Rawat, Y Shin
An electroencephalogram (EEG) based image encryption combined with Quantum walks (QW) is encoded in Fresnel domain. The computational version of EEG randomizes the original plaintext whereas QW can serve as an excellent key generator due to its inherent nonlinear chaotic dynamic behavior. First, a spatially coherent monochromatic laser beam passes through an SLM, which introduces an arbitrary EEG phase-only mask. The modified beam is collected by a CCD. Further, the intensity is multiply with the QW digitally...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226195/global-transcriptional-response-of-human-liver-cells-to-ethanol-stress-of-different-strength-reveals-hormetic-behavior
#16
Wolfgang Schmidt-Heck, Eva C Wönne, Thomas Hiller, Uwe Menzel, Dirk Koczan, Georg Damm, Daniel Seehofer, Fanny Knöspel, Nora Freyer, Reinhard Guthke, Steven Dooley, Katrin Zeilinger
BACKGROUND: The liver is the major site for alcohol metabolism in the body and therefore, the primary target organ for ethanol-induced toxicity. In this study, we investigated the in vitro response of human liver cells to different ethanol concentrations in a perfused bioartificial liver device that mimics the complex architecture of the natural organ. METHODS: Primary human liver cells were cultured in the bioartificial liver device and treated for 24 hours with medium containing 150 mM (low), 300 mM (medium) or 600 mM (high) ethanol, while a control culture was kept untreated...
February 22, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28225465/a-patient-centered-approach-to-developing-entrustable-professional-activities
#17
Carlos El-Haddad, Arvin Damodaran, H Patrick McNeil, Wendy Hu
PURPOSE: The medical education community is rapidly accepting the use of entrustable professional activities (EPAs) as a means of assessing residents. Stakeholder engagement is advised in developing EPAs, but no studies have investigated the role of patient input. In this qualitative study, the authors investigated what patient input may add to designing a patient-centered EPA. METHOD: The authors chose "management of acute low back pain (LBP)" as a common, important clinical task on which to base the patient-centered EPA...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28225464/beyond-selection-the-use-of-situational-judgement-tests-in-the-teaching-and-assessment-of-professionalism
#18
Barbara D Goss, Anna T Ryan, Joshua Waring, Terry Judd, Neville G Chiavaroli, Richard Charles O'Brien, Stephen C Trumble, Geoffrey J McColl
PROBLEM: Professionalism is a critical attribute of medical graduates. Its measurement is challenging. The authors sought to assess final-year medical students' knowledge of appropriate professional behavior across a broad range of workplace situations. APPROACH: Situational judgement tests (SJTs) are used widely in applicant selection to assess judgement or decision making in work-related settings as well as attributes such as empathy, integrity, and resilience...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28225217/proteomic-analysis-of-the-cullin4b-interactome-using-proximity-dependent-biotinylation-in-living-cells
#19
Hailong Zhang, Shupeng Li, Pingting Liu, Frankie H F Lee, Albert H C Wong, Fang Liu
Cullin 4B (CUL4B) mutations have been implicated in mental retardation and dopamine-related behaviors due to disruptions in their interaction with Cullin-RING E3 ligases (CRLs). Thus, further identification of CUL4B substrates can increase the knowledge of protein homeostasis and illuminate the role of CUL4B in neuropsychiatric disease. However, the transient nature of the coupling between CUL4B and its substrates is difficult to detect in vivo using current approaches, thus hampers efforts to investigate functions of CRLs within unperturbed living systems...
February 22, 2017: Proteomics
https://www.readbyqxmd.com/read/28224097/understanding-academic-clinicians-intent-to-treat-pediatric-obesity
#20
Claudia Frankfurter, Charles Cunningham, Katherine M Morrison, Heather Rimas, Karen Bailey
AIM: To examine the extent to which the theory of planned behavior (TPB) predicts academic clinicians' intent to treat pediatric obesity. METHODS: A multi-disciplinary panel iteratively devised a Likert scale survey based on the constructs of the TPB applied to a set of pediatric obesity themes. A cross-sectional electronic survey was then administered to academic clinicians at tertiary care centers across Canada from January to April 2012. Descriptive statistics were used to summarize demographic and item agreement data...
February 8, 2017: World Journal of Clinical Pediatrics
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