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Parenteral nutrition in newborn

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https://www.readbyqxmd.com/read/27884125/epidemiology-of-and-risk-factors-for-neonatal-candidemia-at-a-tertiary-care-hospital-in-western-china
#1
Jichang Chen, Yongjiang Jiang, Ba Wei, Yanling Ding, Shaolin Xu, Peixu Qin, Jinjian Fu
BACKGROUND: The prevalence and clinical characteristics of neonatal candidemia are poorly understood in western China. The aim of our study was to evaluate the epidemiological features of neonatal candidemia in the Liuzhou Maternity and Child Healthcare Hospital. METHODS: A retrospective case-control study was conducted between January 2012 and November 2015. Electronic databases were reviewed and data on Candida species were isolated from blood cultures and candidemia incidence, risk factors, and mortality were extracted...
November 24, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27845942/outcome-differences-between-simple-and-complex-gastroschisis
#2
Vesna Milojkovic Marinovic, Maija Lukac, Zeljko Mikovic, Blagoje Grujic, Maja Milickovic, Gordana Samardzija, Aleksandra Stojanovic, Dalibor Sabbagh
BACKGROUND: We reviewed differences of the outcome of newborn with simple and complex gastroschisis treated at our institution over the past fifteen years. METHODS: A retrospective cohort study was performed on all infants with gastroschisis treated at the Institute for mother and child health care, Belgrade, between 2001 and 2015 (n=70). Premature infants (<34 weeks of gestation) and babies with birth weight less than 1500 g were excluded (n=5). We compared outcomes in infants with simple gastroschisis and those with complex gastroschisis...
October 14, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27836286/acylcarnitine-profiles-reflect-metabolic-vulnerability-for-necrotizing-enterocolitis-in-newborns-born-premature
#3
Karl G Sylvester, Zachary J Kastenberg, R Larry Moss, Gregory M Enns, Tina M Cowan, Gary M Shaw, David K Stevenson, Tiffany J Sinclair, Curt Scharfe, Kelli K Ryckman, Laura L Jelliffe-Pawlowski
OBJECTIVE: To evaluate the association between newborn acylcarnitine profiles and the subsequent development of necrotizing enterocolitis (NEC) with the use of routinely collected newborn screening data in infants born preterm. STUDY DESIGN: A retrospective cohort study was conducted with the use of discharge records for infants born preterm admitted to neonatal intensive care units in California from 2005 to 2009 who had linked state newborn screening results. A model-development cohort of 94 110 preterm births from 2005 to 2008 was used to develop a risk-stratification model that was then applied to a validation cohort of 22 992 births from 2009...
November 8, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27781255/-timing-investigation-of-single-stage-definitive-surgery-for-newborn-with-hirschsprung-s-disease
#4
Shangjie Xiao, Wenyi Yang, Like Yuan, Ying Zhang, Tao Song, Lu Xu, Song Tian, Wuping Ge, Jialiang Zhou, Xiaochun Zhu
OBJECTIVE: To investigate the operation timing of newborns with rectosigmoid Hirschsprung's disease (HD). METHODS: From March 2013 to September 2015, 35 newborns diagnosed as rectosigmoid HD in our department were prospectively and randomly divided into 2 groups: less than 3 months treatment group (18 cases) and more than 3 months treatment group (17 cases, conservative treatment for 3 months). They all underwent laparoscopic-assisted transanal endorectal pull-through (LATEP) (modified Soave) procedure...
October 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27752931/pharmacological-management-of-gestational-diabetes-mellitus
#5
REVIEW
Riki Bergel, Eran Hadar, Yoel Toledano, Moshe Hod
Gestational diabetes mellitus (GDM) is one of the most common morbidities complicating pregnancy, with short- and long-term consequences to the mothers, fetuses, and newborns. Management and treatment are aimed to achieve best possible glycemic control, while avoiding hypoglycemia and ensuring maternal and fetal safety. It involves behavioral modifications, nutrition and medications, if needed; concurrent with maternal and fetal surveillance for possible adverse outcomes. This review aims to elaborate on the pharmacological options for GDM therapy...
November 2016: Current Diabetes Reports
https://www.readbyqxmd.com/read/27749612/congenital-sucrase-isomaltase-deficiency-a-novel-compound-heterozygous-mutation-causing-aberrant-protein-localization
#6
Yael Haberman, Ayelet Di Segni, Nurit Loberman-Nachum, Ortal Barel, Vered Kunik, Eran Eyal, Nitzan Kol, Goni Hout-Siloni, Brigitte Kochavi, Camila Avivi, Michael Schvimer, Gideon Rechavi, Yair Anikster, Iris Barshack, Batia Weiss
OBJECTIVES: Congenital chronic diarrhea (CCD) is a group of inherited enteropathies presenting in early life and requiring parenteral nutrition. In most cases, genetics may be the key for precise diagnosis. We present an infant girl with CCD that resolved after introduction of fructose-based formula but had no identified mutation in the SLC5A1 gene. Using whole exome sequencing (WES) we identified other mutations that better dictated dietary adjustments. METHODS: WES of the patient and her parents was performed...
October 4, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27665495/high-mortality-among-children-with-gastroschisis-after-the-neonatal-period-a-long-term-follow-up-study
#7
Kirsten Risby, Steffen Husby, Niels Qvist, Marianne S Jakobsen
BACKGROUND: During the last decades neonatal outcomes for children born with gastroschisis have improved significantly. Survival rates >90% have been reported. Early prenatal diagnosis and increased survival enforce the need for valid data for long-term outcome in the pre- and postnatal counseling of parents with a child with gastroschisis. METHODS: Long-term follow-up on all newborns with gastroschisis at Odense University Hospital (OUH) from January 1 1997-December 31 2009...
September 2, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27624996/pregnancy-is-possible-on-long-term-home-parenteral-nutrition-in-patients-with-chronic-intestinal-failure-results-of-a-long-term-retrospective-observational-study
#8
Lore Billiauws, Laura Armengol Debeir, Florian Poullenot, Cécile Chambrier, Nicolas Cury, Pierre-François Ceccaldi, Emilie Latour Beaudet, Olivier Corcos, Evelyne Marinier, Olivier Goulet, Eric Lerebours, Francisca Joly
BACKGROUND & AIMS: Home parenteral nutrition (HPN) improves survival and quality of life in patients with chronic intestinal failure (IF). Few cases of pregnancy on HPN have been published. The aim of this study was to report pregnancy cases on long-term HPN in benign IF. METHODS: This retrospective study included all pregnant patients on HPN from 4 HPN referral centers. Data on demographics, ongoing pathology, HPN type, maternal and newborn complications were collected...
August 23, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27621005/nonoperative-management-of-esophageal-perforations-in-the-newborn
#9
Ekene A Onwuka, Payam Saadai, Laura A Boomer, Benedict C Nwomeh
BACKGROUND: Esophageal perforation in neonates occurs most often in cases of extreme prematurity and is commonly due to iatrogenic causes. Treatment over recent decades has become more conservative. The purpose of this study was to review cases of esophageal perforation in neonates and to describe the presentation, management, and outcomes. MATERIALS AND METHODS: A retrospective chart review was performed for patients with International Classification of Diseases, Ninth Revision code for esophageal perforation treated at our institution between the years 2009 and 2015...
September 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27583439/total-antioxidant-total-oxidant-and-serum-paraoxonase-levels-according-to-lipid-administration-method-in-parenterally-fed-premature-infants
#10
Murat Konak, Nuriye Tarakci, Hüseyin Altunhan, Ali Annagür, Aysun Toker, Rahmi Örs
OBJECTIVE: The aim of our study was to determine whether lipid solutions delivered separately or in mixture with total parenteral nutrition (TPN) solutions effect the balance between oxidant and antioxidant levels in premature infants. METHODS: A total of 60 preterm newborns who were delivered at their 30-34 gestational weeks and received TPN were included in the study. Premature newborns were randomized into two groups based on the delivery method of the lipid solution, separately (Group 1) or in mixture with TPN solutions (Group 2)...
September 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27327804/peripherally-inserted-central-catheters-vs-peripheral-cannulas-for-delivering-parenteral-nutrition-in-neonates
#11
COMMENT
Sean B Ainsworth, William McGuire
CLINICAL QUESTION: Is parenteral nutrition via peripherally inserted central catheters (PICCs) associated with better delivery of nutrition and growth and fewer adverse events compared with short peripheral cannulas in neonates? BOTTOM LINE: Compared with short peripheral cannulas, parenteral nutrition via PICCs is associated with better nutrient delivery and lower rates of subsequent catheters or cannulas placed and is not associated with increased rates of invasive infection...
June 21, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27303483/megacystis-microcolon-intestinal-hypoperistalsis-syndrome
#12
Paul Clark, Stephen C O'Connor
We report a case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) in a newborn female infant who presented with an abdominal mass, absent bowel sounds, and feeding intolerance with bilious emesis. MMIHS is a rare congenital bowel and bladder defect requiring surgery and chronic total parenteral nutrition in an attempt to sustain life. With few exceptions, it is predominately fatal within the first six months of life. We describe the relevant clinical and radiologic findings with ultrasound correlation of this case followed by a brief review of literature included in the discussion...
2007: Radiology case reports
https://www.readbyqxmd.com/read/27109993/neonatal-serial-transverse-enteroplasty-step-case-report
#13
P A Lobos, S E M Calello, V B Busoni, M M Urquizo Lino, S G Prodan, R Sanchez Claria
CASE REPORT: Gastroschisis is the most frequent congenital abdominal wall defect. When associated with intestinal atresia (complex gastroschisis), short bowel syndrome may occur. Complicated gastroschisis is the most frequent cause of short bowel syndrome in our series. The serial transverse enteroplasty procedure has been used to lengthen the bowel and achieve intestinal rehabilitation in patients with dilated gut. The use of this technique in the newborn period, for tailoring the bowel while preserving absorptive mucosa, has been recently described...
March 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27084698/percutaneously-inserted-central-catheter-related-pleural-effusion-in-a-level-iii-neonatal-intensive-care-unit-a-5-year-review-2008-2012
#14
Rani A Bashir, Allison M Callejas, Horacio C Osiovich, Joseph Y Ting
BACKGROUND: Although peripherally inserted central catheters (PICCs) provide vascular access in newborns who require parenteral nutrition and medications, they can be associated with complications that lead to significant morbidity and mortality. OBJECTIVES: To describe the characteristics of pleural effusion (PLE) associated with PICC use in a large level III neonatal intensive care unit. DESIGN/METHODS: A retrospective review of PICC-related PLE in newborns was conducted over a 5-year period, from 2008-2012...
April 15, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27079965/a-comparison-of-3-vitamin-d-dosing-regimens-in-extremely-preterm-infants-a-randomized-controlled-trial
#15
Prem Fort, Ariel A Salas, Teodora Nicola, Carolyne M Craig, Waldemar A Carlo, Namasivayam Ambalavanan
OBJECTIVE: To determine the optimal dose of vitamin D supplementation to achieve biochemical vitamin D sufficiency in extremely low gestational age newborns in a masked randomized controlled trial. STUDY DESIGN: 100 infants 23 0/7-27 6/7 weeks gestation were randomized to vitamin D intakes of placebo (n = 36), 200 IU (n = 34), and 800 IU/d (n = 30) (approximating 200, 400, or 1000 IU/d, respectively, when vitamin D routinely included in parenteral or enteral nutrition is included)...
July 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27077685/respiratory-morbidity-in-late-preterm-infants
#16
Claudia Correia, Gustavo Rocha, Filipa Flor-DE-Lima, Hercília Guimarães
BACKGROUND: Late preterm delivery (74% of all preterm births) increases the incidence of respiratory pathology, namely respiratory distress syndrome (RDS), transient tachypnea of the newborn (TTN) and the need of ventilator support when compared to term delivery. The aim is to evaluate the respiratory morbimortality in late preterm infants and the risk factors associated with RDS and TTN. METHODS: Descriptive retrospective study of all newborns of 34+0 to 36+6 weeks of gestational age, born at our centre between September 1, 2012 and August 31, 2015...
April 14, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27056029/parenteral-nutrition-solution-in-cerebrospinal-fluid-in-preterm-newborn-a-case-report-and-review-of-the-literature
#17
Monika Lachowska, Krzysztof Lachowski, Barbara Królak-Olejnik
INTRODUCTION: Percutaneously inserted central venous catheters (epicutaneo-cava-catheter - ECC) are widely used in neonatal intensive care, facilitating the parenteral nutrition and the treatment of critically ill newborns. This invasive procedure is regarded as safe and associated with low complication rate. Possible life-threatening complications may result from malpositioning of ECC. Paraspinal misplacement of ECC is one of the most serious complications. CASE PRESENTATION: The authors report a case of misplacement of ECC inserted via left saphenous vein for intravenous feeding...
2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/26965762/amino-acid-dosing-in-parenteral-nutrition-for-very-low-birth-weight-preterm-neonates-an-outcome-assessment
#18
Nor Aini Kamarudin, Mohamed Mansor Manan, Hanis Hanum Zulkifly, Chin Fen Neoh, Salmiah Mohd Ali, Long Chiau Ming
This study aimed to investigate the effects of parenteral nutrition (PN) administration of amino acids (AA) on physical changes among very low birth weight infants in a local hospital setting in Malaysia. A retrospective study was carried out at a hospital in Malaysia. Records of neonates prescribed PN in the neonatal unit in 2012 were screened for eligibility. A total of 199 premature neonates received PN support in the year 2012 and, of these, 100 fulfilled the inclusion criteria. The median value of AA intake on the first day of PN was 2...
2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26965761/early-enteral-nutrition-in-neonates-with-partial-gastrectomy-a-multi-center-study
#19
MULTICENTER STUDY
Weiwei Jiang, Jie Zhang, Qiming Geng, Xiaoqun Xu, Xiaofeng Lv, Yongwei Chen, Xiang Liu, Weibing Tang
BACKGROUND AND OBJECTIVES: Compared with total parenteral nutrition (TPN), enteral nutrition is more suitable for patients post-operatively. Our aim was to determine the safety and feasibility of early enteral nutrition (EEN) using a jejunum feeding tube in neonates after undergoing a partial gastrectomy. METHODS AND STUDY DESIGN: This was a retrospective review of 46 patients who underwent partial gastrectomies for gastric perforation in our hospital. These patients were categorized into two groups (EEN group [n=24 patients], a jejunal feeding tube was inserted during surgery; and a control group [n=22 patients], a jejunal feeding tube was not placed)...
2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26867308/-ca-p-and-mg-postnatal-metabolism-and-requirements-in-parenteral-and-enteral-nutrition-of-premature-infants
#20
C Pieltain, Th Senterre, V De Halleux, J Rigo
During the last trimester of gestation, transplacental mineral transfer and fetal mineral accretion is particularly high: 2.3-3.2 mmol/kg/day (90-130 mg/kg/d) of calcium, 2.4-2.7 mmol/kg/d (65-75 mg/kg/day) of phosphorus and 0.12-0.20 mmol/kg/d (2.9-4.8 mg/kg/day) of magnesium. After birth, there is a dramatic change in bone mineral metabolism from a maximal bone deposition during fetal life to a postnatal bone turnover stimulation improving bone structure and resistance. This physiological change could partly reduce the mineral requirements, as minerals available from the remodeling activities could be recycled for bone mineralization...
December 2015: Revue Médicale de Liège
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