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Muhammad Furrakh Maqbool, Muhammad Sajid, Ahmed Noeman
Among the rare and well-known causes of sudden cardiac death by malignant arrthymias is a condition called arrhythmogenic right ventricular cardiomyopathy. It commonly presents with right ventricular dilatation, dysfunction and ventricular tachycardia of left bundle branch morphology due to fibro-fatty infiltration of right ventricle in second to fifth decade of life, making it an unrecognized and important cause of sudden cardiac death. Two rare variants of arrhythmogenic right ventricular cardiomyopathy are Carvajal syndrome and Naxos syndrome...
April 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Jonathan E Harms, J Matthew Kuczmarski, Joyce S Kim, Gail D Thomas, Marc P Kaufman
KEY POINTS: Ligating the femoral artery of a rat for 72 h, a model for peripheral artery disease, causes an exaggerated exercise pressor reflex in response to muscle contraction. Likewise, the hindlimb muscles of rats with ligated femoral arteries show increased levels of reactive oxygen species. Infusion of tiron, a superoxide scavenger, attenuated the exaggerated pressor reflex and reduced reactive oxygen species production in rats with ligated femoral arteries. Conversely, we found no effect of tiron infusion on the pressor reflex in rats with patent femoral arteries...
July 1, 2017: Journal of Physiology
Derya Karasu, Canan Yılmaz, Şeyda Efsun Özgünay, Mürüvvet Dayıoğlu, Çağdaş Baytar, Gülsen Korfalı
OBJECTIVE: Cardiovascular system depression, respiratory arrest, coma, convulsions, loss of consciousness, muscle twitching, blurred vision, vertigo, dizziness and numbness of the tongue can be seen in local anaesthetic toxicity. Treatment includes 20% lipid solutions, airway control, symptomatic treatment for arrhythmia and convulsions. The aim of this study is to present the knowledge of research assistants, who used local anaesthetics in daily practice, regarding these medications and toxicity treatment and to raise awareness...
August 2016: Turkish Journal of Anaesthesiology and Reanimation
Mariusz Wolbinski, Andrew H Swain, Scott A Harding, Peter D Larsen
BACKGROUND: The proportion of patients suffering out-of-hospital cardiac arrest presenting with ventricular arrhythmias/ventricular fibrillation (VT/VF) is decreasing, while the proportion presenting with pulseless electrical activity (PEA) is increasing. Cardiac arrest interventions target VT/VF and survival rates from PEA are much lower. The aim of this study was to compare clinical characteristics of those suffering PEA and VT/VF. METHODS: We examined the past medical history of all patients suffering cardiac arrest in the Wellington region between 2008-2012 and compared clinical features of those with PEA to VT/VF...
July 2016: Heart, Lung & Circulation
Xianhui Zhou, Wenhui Zhang, Wenkui Lv, Qina Zhou, Yaodong Li, Ling Zhang, Yanmei Lu, Jianghua Zhang, Qiang Xing, Hongli Wang, Baopeng Tang
BACKGROUND: Atrial fibrillation (AF) is an arrthymia characterized by increased risk of ventricle arrthymias and thromboembolism especially ischemic stroke. Most thrombus originated in the left atrial appendage, thus left atrial occlusion (LAAO) may be an effective alternative for stroke prevention in atrial fibrillation. OBJECTIVE: To assess the effect and safety of left atrial occlusion for stroke prevention in atrial fibrillation. METHODS AND RESULTS: We searched Pub Med, CENTRAL in The Cochrane Library, Embase, CBM-Disk, CNKI for published trials, ClinicalTrials...
January 15, 2016: International Journal of Cardiology
Elnur Alizade, Anıl Avcı, Serdar Fidan, Mustafa Tabakçı, Mustafa Bulut, Regayip Zehir, Zeki Simsek, Mert Evlice, Uğur Arslantaş, Hakan Çakır, Mehmet Yunus Emiroglu, Mustafa Akçakoyun
BACKGROUND: The chronic consumption of androgenic anabolic steroids has shown to cause atrial arrhythmias. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate repolarization dispersion measured from the 12-lead surface electrocardiogram (including Tp-e interval, Tp-e/QT ratio, and Tp-e/cQT ratio) in bodybuilders who are using anabolic androgenic steroids (AAS)...
November 2015: Annals of Noninvasive Electrocardiology
Garick Hill
Tetralogy of Fallot is the most common cyanotic congenital heart defect. Advances in surgical technique and postoperative care have improved survival which is now very good. Patients now face long-term morbidities such as reduced exercise tolerance and arrthymias. Cardiologists caring for these patients are confronted with decisions regarding best care practices. This article will review the evidence available on repair and postoperative follow-up for patients with Tetralogy of Fallot with pulmonary stenosis...
March 2013: Congenital Heart Disease
Krishnan Muralikrishnan, Kabali Balasubramanian, Badanidiyur Viswanatha Rao
Hypertension (HT) is a major silent disease affecting young people because of their hereditary and modern lifestyles. Target organ damages occur before overt hypertension is diagnosed. Many offspring of HT parents show early changes in their cardiovascular autonomic functions. Heart rate variability (HRV) provides a window to understand the cardiac autonomic balance. This study was designed to quantify and to compare the HRV among the normotensive young male offspring without history of parenteral hypertension & diabetic (control group, n = 25, age 20...
July 2011: Indian Journal of Physiology and Pharmacology
Dilşen Ornek, Gözde Bumin Aydın, Kadriye Kahveci, Fatma Ciçek, Bayazıt Dikmen
Marfan syndrome is an autosomal dominant heritable disorder of the connective tissue that involves primarily the skeletal, ocular, and cardiovascular systems. Turner syndrome is a genetic disorder resulting from partial or complete X chromosome monosomy. We report the anesthetic management of a case of Marfan-Turner syndrome, which is the first such case to appear in the literature to our knowledge. A 3 year old ASA III girl was scheduled to undergo minor plastic surgery. She had a short webbed neck, prognathism, micrognathia, low-set ears, and a high palate...
June 2012: Journal of Anesthesia
Khairul Azami Sidek, Ibrahim Khalil
This paper presents a person identification mechanism in irregular cardiac conditions using ECG signals. A total of 30 subjects were used in the study from three different public ECG databases containing various abnormal heart conditions from the Paroxysmal Atrial Fibrillation Predicition Challenge database (AFPDB), MIT-BIH Supraventricular Arrthymia database (SVDB) and T-Wave Alternans Challenge database (TWADB). Cross correlation (CC) was used as the biometric matching algorithm with defined threshold values to evaluate the performance...
2011: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Britt-Maria Beckmann, Arne Pfeufer, Stefan Kääb
BACKGROUND: The incidence of sudden cardiac death in persons under age 40 is roughly 3 per 100 000 persons per year in Germany and North America. Many of these deaths are found to be due to hereditary heart diseases, often a primary structural heart disease associated with arrhythmia or else a primary arrhythmia syndrome in a structurally normal heart. Such diseases are usually of autosomal dominant inheritance, often affect otherwise healthy persons, and can generally be well treated if recognized early...
September 2011: Deutsches Ärzteblatt International
Henning Clausen, Theane Theophilos, Kim Jackno, Franz E Babl
OBJECTIVE: Emergency department (ED) staff need to rapidly establish accurate diagnosis and management for children with arrhythmias. Limited data are available on the presenting features, epidemiology and management of arrhythmias encountered in the ED. The aim of this study was to characterise the incidence, presenting features, management and outcomes of arrhythmias at a large tertiary children's hospital ED. PATIENTS AND METHODS: Retrospective review of medical records identified via the ED electronic database using ICD-10 codes for arrhythmias including cardiac arrests over a 6-year period (2002-2008)...
September 2012: Emergency Medicine Journal: EMJ
Susan Duncan, Martin J Brodie
Sudden unexpected death in epilepsy (SUDEP) has an incidence ranging between 0.09 and 9 per 1000 patient-years depending on the patient population and the study methodology. It is the commonest cause of death directly attributable to epilepsy, and occurs at or around the time of a seizure. The principal risk factor for SUDEP is poorly controlled generalized tonic-clonic seizures. Other risk factors include polytherapy, male sex, early age at onset of epilepsy, symptomatic etiology, and, possibly, treatment with lamotrigine...
August 2011: Epilepsy & Behavior: E&B
Yao Wang, Zhuo-Jun Huang, Jun-Qiu Song, Yan-Na Wu, Yan-Xia Liu
AIM: To study the protective effects of ramipril in combination with BQ-123 on myocardial ischemia/reperfusion (I/R) injury in vivo in anesthetized rats. METHODS: Healthy male Wistar rats were divided into 5 groups randomly and subjected to 30 min of myocardial ischemia followed by 120 min reperfusion. Ramipril, BQ-123 and their combination were given to rats respectively. To observe the protection of their combination against myocardial I/R injury. HR, MAP and the change of ST-segment were observed...
November 2009: Chinese Journal of Applied Physiology
D Liu, F Zhao, B Ge, H Zhao, Y Guo, B Shi
BACKGROUND: To analyze the short-term effects and long term survival of patients with lung cancer underwent tracheal carina reconstruction and bronchoplasty. METHODS: From April 1985 to May 1999, 94 patients with lung cancer underwent tracheal carina reconstruction and bronchoplasty, 14 for carinal resection and reconstruction and 80 for bronchial sleeves. RESULTS: Postoperative complications were atelectasis ( 19 cases) , arrthymia ( 2 cases) and anastomotic leakage ( 1 case) ...
August 20, 2000: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Liwei Huang, Chen Li, Jianjun Xu, Chan Zhou, Hong Tang, Li Rao
Tei-Index is a useful echocardiographic parameter for evaluating global cardiac function. Conventionally, a value and b value, which the calculation of Tei index is based on, are measured in different cardiac cycle. Therefore, accuracy of Tei index is damaged by cycle dependent variation, especially in patients with arrhythmia. The newly established Dual Doppler modality allows a synchronous measurement of both a value and b value. This study was aimed to explore the value of Tei index measured by Dual Doppler in cardiac function estimation in patients with hypertension...
June 2010: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
Sumit Sarkar, Larry Schmued
"Ecstasy" (MDMA) is a powerful hallucinogenic drug which has raised concern worldwide because of its high abuse liability. A plethora of studies have demonstrated that MDMA has the potential to induce neurotoxicity both in human and laboratory animals. Although research on MDMA has been carried out by many different laboratories, the mechanism underlying MDMA induced toxicity has not been fully elucidated. MDMA has the ability to reduce serotonin levels in terminals of axons in the cortex of rats and mice...
August 2010: Current Pharmaceutical Biotechnology
David H Spodick, Vignendra Ariyarajah, Robert Goldberg
BACKGROUND AND HYPOTHESIS: Interatrial block (IAB: P-duration > 100 ms) is poorly recognized in hospital populations. In addition to reduced left atrial function and left atrial enlargement it predicts atrial fibrillation and other arrthymias. P-terminal force (Ptf): +/- biphasic P in lead V(1) > or = area of 1 small square on the electrocardiogram (ECG) grid also indicates left atrial abnormality, particularly left atrial enlargement. These 2 should be related. We determined the intercorrelation...
April 2009: Clinical Cardiology
Rogério Ferreira da Silva, Karina Morgarbel, Christian Moreno Luize, Carla Gonçalves Rosa, Marcelo Romano, Ieda Maria Liguori
Arritmogenic right ventricular dysplasia (ARVD) is characterized by the gradual replacement of myocytes by adipose and fibrous tissue. Described in 1977, is considered a potentially lethal cause of cardiac disease poorly understood. This disorder usually involves the right ventricle and has been associated with arrthymia, heart failure, and sudden death. In this paper, we report a case of a 25-year-old patient with syncope associated with ventricular extrasystoles. A magnetic resonance imaging was performed and showed findings that support ARVD diagnose...
October 2008: Arquivos Brasileiros de Cardiologia
Mesut Demir, Saime Paydaş, Murat Cayli, Onur Akpinar, Mustafa Balal, Esmeray Acartürk
OBJECTIVE: Cardiac deposition of AA amyloidosis may result in increasing left ventricular mass and systolic and diastolic dysfunction (DD). The aim of this study was to investigate the left ventricular systolic and diastolic functions by both tissue Doppler imaging (TDI) and pulsed wave Doppler echocardiography (PWD) in patients with AA amyloidosis without congestive heart failure symptoms or arrthymia. METHODS AND RESULTS: Twenty-four patients with AA amyloidosis without congestive heart failure symptoms or arrthymia (15 men and nine women; mean age 44...
2005: Renal Failure
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