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pediatric proptosis

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https://www.readbyqxmd.com/read/29765949/a-20-year-retrospective-review-of-retinoblastoma-at-two-tertiary-academic-hospitals-in-johannesburg-south-africa
#1
Saadiah Goolam, Hemant Kana, Nicky Welsh, Linda Wainwright, Janet Poole, Ismail Mayet
Aim: This paper presents a 20-year review of retinoblastoma in Johannesburg, South Africa, aiming to better characterize the disease in this sub-Saharan setting. Methods: The study represents a retrospective case series of retinoblastoma patients presenting to Charlotte Maxeke Johannesburg Academic Hospital and Chris Hani Baragwanath Academic Hospital between January 1, 1992, and December 31, 2011. Results: The total number of cases identified was 282, with 245 meeting the study inclusion criteria...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29755276/primary-mesenchymal-chondrosarcoma-of-the-orbit-histopathological-report-of-3-pediatric-cases
#2
Hind M Alkatan, Charles G Eberhart, Khalid M Alshomar, Sahar M Elkhamary, Azza M Y Maktabi
Mesenchymal chondrosarcoma (MCS) is an unusual tumor mainly found in the skeleton. Around third of the cases occur in extra-skeletal sites with the orbit being the third most common site in these cases. In previous reviews of the orbital cases, it has been concluded that orbital MCS tends to occur in women in the second or third decades of life. However, 8 cases of orbital MCS have been reported so far in the pediatric age group (age less than 18 years-old) one of which has been considered congenital MCS in a 5-days old newborn girl...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29651357/respiratory-epithelial-orbital-cyst-a-case-report-and-literature-review
#3
Sally Al Abdulmohsen, Ayman Ayoubi, Sadeq Al-Dandan
A 44-year-old male with schizophrenia presented with progressive right proptosis for one year and conjunctivitis for two months. An orbital cyst was seen in the superotemporal region on computerized tomography and was surgically removed. There was no history or radiological signs of paranasal sinus disease or previous trauma. Histopathologic evaluation revealed a cyst lined with respiratory epithelium. Respiratory choristomatous cysts of the orbit are considered rare in both pediatric and adult patients. We review the literature of respiratory orbital cysts and conclude that they tend to present in adults and should be considered in the differential diagnoses of orbital cysts...
2018: Case Reports in Pathology
https://www.readbyqxmd.com/read/29552266/pediatric-mandibular-metastasis-a-rare-finding-of-neuroblastoma
#4
Gregory Wade, Jonathan Revels, Lauren Hartman, Wendy Brown
We present a case of metastatic neuroblastoma to the mandible in an 11-month-old patient presenting with worsening right-sided proptosis and scalp swelling after a fall 2 weeks prior. Initial evaluation with computed tomography of the head demonstrated soft tissue masses centered at the right sphenoid and right mandible. These masses proved to be metastatic lesions from an intra-abdominal neuroblastoma. Review of the literature revealed 20 cases of neuroblastoma metastasis to the mandible over the past 70 years...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29483802/evaluation-of-patients-with-orbital-infections
#5
Deniz Aygün, Cezmi Doğan, Mustafa Hepokur, Osman Şevki Arslan, Haluk Çokuğraş, Yıldız Camcıoglu
Aim: Orbital tissue infections are common infections of childhood that can lead to severe complications. Herein, we aimed to evaluate the etiologic factors, diagnosis, follow-up, and treatment procedures in pediatric patients with orbital infections. Material and Methods: This study was performed retrospectively between January 2014 and December 2015 in Cerrahpasa Medical Faculty Pediatric Infectious Disease Unit. Patients were studied for age, ophthalmologic examination features, laboratory and radiology results, treatment modalities, and the response to these treatments...
December 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/29382496/-orbital-cellulitis-complicated-by-subperiosteal-abscess-due-to-streptococcus-pyogenes-infection
#6
José Daniel Ruíz Carrillo, Edwin Vázquez Guerrero, Mónica Cecilia Mercado Uribe
BACKGROUND: Orbital cellulitis is an infectious disease that is very common in pediatric patients, in which severe complications may develop. Etiological agents related to this disease are Haemophilus influenzae B, Staphylococcus aureus, Streptococcus pneumoniae and Moraxella catarrhalis, which correspond to 95% of cases. Moreover, Streptococcus beta hemolytic and anaerobic microorganisms may also be present corresponding to < 5% of the cases. We present an uncommon case of cellulitis complicated by sub-periosteal abscess caused by Streptococcus pyogenes (Group A beta hemolytic streptococcus)...
March 2017: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29283944/a-giant-osteoma-of-the-ethmoid-sinus
#7
Tatsuyuki Ishii, Yoshiaki Sakamoto, Tomoru Miwa, Kazunari Yoshida, Kazuo Kishi
Osteomas are slow-growing, benign bony tumors. Most are asymptomatic. Paranasal sinus osteoma in the pediatric population is rare; hence, there are few reports of symptomatic osteomas. The authors report the case of a giant ethmoid sinus osteoma in an 11-year-old girl who presented with diplopia and proptosis. Total excision and reconstruction of the medial orbital wall were performed via a coronal approach. The postoperative period was uneventful, the child's vision improved, and a good cosmetic result was obtained...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29248536/orbital-cellulitis
#8
REVIEW
Theodora Tsirouki, Anna I Dastiridou, Nuria Ibánez Flores, Johnny Castellar Cerpa, Marilita M Moschos, Periklis Brazitikos, Sofia Androudi
Orbital cellulitis (OC) is an inflammatory process that involves the tissues located posterior to the orbital septum within the bony orbit, but the term generally is used to describe infectious inflammation. It manifests with erythema and edema of the eyelids, vision loss, fever, headache, proptosis, chemosis, and diplopia. OC usually originates from sinus infection, infection of the eyelids or face, and even hematogenous spread from distant locations. OC is an uncommon condition that can affect all age groups but is more frequent in the pediatric population...
December 15, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29225963/the-influence-of-juvenile-graves-ophthalmopathy-on-graves-disease-course
#9
Jurate Jankauskiene, Dalia Jarusaitiene
Purpose: To investigate juvenile Graves' ophthalmopathy (GO) signs and compare Graves' disease (GD) course in patients with or without GO. Patients and Methods: There were analyzed data (visual acuity, proptosis, palpebral fissure measurements, clinical activity score (CAS), and the course of GD) of 67 children who have been newly diagnosed with GD. 26.9% of patients with GD had signs of ophthalmopathy (GO+), and 73.1% were without ophthalmopathy (GO-). Results: Upper eyelid retraction (72...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29170837/post-traumatic-carotid-cavernous-fistula-in-a-pediatric-patient-a-case-based-literature-review
#10
Barbara Albuquerque Morais, Vitor Nagai Yamaki, Jose Guilherme Mendes Pereira Caldas, Wellingson Silva Paiva, Hamilton Matushita, Manoel Jacobsen Teixeira
BACKGROUND: Carotid-cavernous fistula (CCF) is a shunt between the carotid artery and the cavernous sinus. Traumatic CCFs are diagnosed in 0.2% of head traumas being only 4.6% of the pediatric population. Classified by Barrow in 1985, type A CCF is the most frequent, occurring in 75% of cases. Type A is characterized by direct and high-flow CCF that generally can occur as a result of traumatic injury or rupture of an intracavernous aneurysm. CASE PRESENTATION: The subject was an 8-year-old boy with penetrating trauma to his left eye...
March 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29131914/pediatric-orbital-primitive-neuroectodermal-tumors
#11
Tayyab Afghani, Hassan Mansoor, Syed Naeem Raza Hamdani
PURPOSE: To present the clinical, radiological, histopathological, immunohistochemical features and the follow-up of orbital primitive neuroectodermal tumors (PNETs) in pediatric patients along with a review of the literature. METHODS: A retrospective analysis of all diagnosed cases of orbital PNET was done. Patients' ophthalmic findings, imaging, immunohistochemistry, metastatic work-up, treatment, globe salvation, and survival were documented and a mini literature review of orbital PNET was performed...
March 1, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29019756/imaging-of-skeletal-disorders-caused-by-fibroblast-growth-factor-receptor-gene-mutations
#12
Kiran M Sargar, Achint K Singh, Simon C Kao
Fibroblast growth factors and fibroblast growth factor receptors (FGFRs) play important roles in human axial and craniofacial skeletal development. FGFR1, FGFR2, and FGFR3 are crucial for both chondrogenesis and osteogenesis. Mutations in the genes encoding FGFRs, types 1-3, are responsible for various skeletal dysplasias and craniosynostosis syndromes. Many of these disorders are relatively common in the pediatric population, and diagnosis is often challenging. These skeletal disorders can be classified based on which FGFR is affected...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28918531/penetrating-orbital-trauma-leading-to-trans-orbital-brain-herniation
#13
Siddharth Vankipuram, Chittij Srivastava, B K Ojha, Sushant Sahoo
INTRODUCTION: Development of a posttraumatic herniation of brain parenchyma through the orbit is a rare complication of orbital roof fracture. Mostly, the injury is due to a direct impact to the frontal region resulting in orbital roof fracture with dural defect and herniation of cerebrospinal fluid or brain parenchyma. These patients present with acute or gradually progressive proptosis with impending risk of loss of vision and mandate surgical decompression of optic nerve with watertight closure of the dural defect...
February 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28868275/recurrent-orbital-solitary-fibrous-tumor-in-a-12-year-old
#14
Alexander F Vu, Rao V Chundury, Alexander D Blandford, Julian D Perry
PURPOSE: To report the clinical features and pathology of orbital solitary fibrous tumors and present a case of a recurrence in a 12-year-old boy. METHODS: Case Report. RESULTS: A 12-year-old boy presented to our institution with double vision in upgaze for 6 months. Examination revealed 3 mm of left-sided proptosis, hypoglobus, and -3 impairment of supraduction. Magnetic resonance imaging of the orbits showed an avidly enhancing mass within the superolateral aspect of the orbit...
July 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/28700400/treatment-of-pediatric-igg4-related-orbital-disease-with-tnf-%C3%AE-inhibitor
#15
Sanjai Jalaj, Kristen Dunbar, Ashley Campbell, Michael Kazim
The authors describe a 9-year-old female who presented with swelling, proptosis, and tenderness of the right upper eyelid and MRI imaging demonstrating right lacrimal gland enlargement. After failing treatment with corticosteroids, the patient underwent a biopsy that was consistent with IgG4-related orbital disease. She was subsequently successfully treated with adalimumab (TNF-α inhibitor). This is the first case report of the successful use of a TNF-α inhibitor for the treatment of IgG4-related orbital disease in a child...
January 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28596822/ethmoid-malformation-associated-with-pediatric-nasal-polyposis-and-allergic-fungal-sinusitis
#16
Cameron G Hanson, Todd B Proctor
A 17-year-old female with allergic fungal sinusitis and nasal polyposis presented with epistaxis in the emergency room. On examination, right-sided proptosis and irregular nasal obstruction were observed in the right nasal cavity. CT imaging revealed massive right-sided polyposis and significant ipsilateral malformation with boney architecture preservation of the ethmoidal labyrinth and lamina papyracea. The patient was treated surgically with symptomatic improvement. These findings indicate a unique malformation of the ethmoid while the patient was in development...
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28576543/pycnodysostosis-at-otorhinolaryngology
#17
Tekin Baglam, Adem Binnetoglu, Muhammet Fatih Topuz, Nilay Baş Ikizoglu, Refika Ersu, Serap Turan, Murat Sarı
AIM: Pycnodysostosis is a rare autosomal, recessive, skeletal dysplasia caused by a mutation in the cathepsin k gene. Pycnodysostosis is characterized by short stature, characteristic facial appearance (delayed closure of fontanelles and cranial sutures, mandibular hypoplasia and angle disorder, blue sclera), and acroosteolysis of the distal phalanges. Our aim was to describe the otorhinolaryngologic findings, differential diagnoses, various treatment options, and followup in eight cases of pycnodysostosis...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28558378/pial-arteriovenous-fistula-and-capillary-malformation-arteriovenous-malformation-associated-with-rasa1-mutation-2-pediatric-cases-with-successful-surgical-management
#18
A Jessey Chugh, Asim Shahid, Sunil Manjila, Deepak Gulati, Nicholas C Bambakidis
We present case reports of 2 pediatric patients who were both found to have pial arteriovenous fistulas (AVFs) with subsequent genetic analysis revealing mutations in the RASA1 gene. Considering their family history of distinct cutaneous lesions, these mutations were likely inherited as opposed to de novo mutations. Patient 1 had large capillary malformations on the left side of the face and neck, associated with macrocephaly, and presented at the age of 32 months with speech delay, right-sided weakness, and focal seizures involving the right side of the body...
2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28520318/-image-of-the-month-a-pediatric-case-of-unilateral-proptosis-and-cystic-lymphangioma
#19
L Adouane, Ch Chantrain, M Lewin, P Philippet, M Thimmesch
No abstract text is available yet for this article.
May 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28468165/orbital-reconstruction-in-neuroectodermal-tumor-of-the-orbit-multimodal-treatment-approach
#20
Jorge Ernesto Cantini A, Diana M Díaz López, Esteban Francisco Hernandez Florez
INTRODUCTION: Primitive neuroectodermal tumors of peripheral origin are very rare, and orbital neuroectodermal tumors are even more uncommon. Only 25 patients with primary orbital involvement in the pediatric age group have been reported. METHODS: In this article, the authors describe their experience in the multimodality treatment approach to treat neuroectodermal tumor of the orbit. The authors also present a male patient 3-year old presenting with a neuroectodermal tumor of the right orbit causing rapidly progressive proptosis...
May 2017: Journal of Craniofacial Surgery
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