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pediatric proptosis

Ritesh R Kalaskar, Ashita R Kalaskar
Neuroblastoma is an extremely rare pediatric neoplasm whose prognosis becomes poor and poor as the age advances. It can be sporadic or nonfamilial in origin. It is primarily a tumor of abdominal origin from where it metastasis to lymph nodes, liver, intracranial and orbital sites, and central nervous system. There is no standard dental treatment protocol for the management of neuroblastoma due to its poor survival rate and rarity. However, dental treatment may follow the protocol of preventive and restorative...
July 2016: Contemporary Clinical Dentistry
A Daoudi, S Ajdakar, N Rada, G Draiss, I Hajji, M Bouskraoui
Orbital cellulitis in children is a rare but potentially serious condition. The goal of this study is to analyze the epidemiological, clinical, therapeutic aspects and typical course of orbital and periorbital cellulitis in children, so as to propose a clinical management protocol adapted to our context. During the retrospective study period (2008-2014), 28 cases were hospitalized in the pediatric department at the Mohammed VI university medical center in Marrakech. Eighty-five percent of the cases were diagnosed as preseptal cellulitis, and 15% as retroseptal cellulitis...
September 2016: Journal Français D'ophtalmologie
Emily Parkhurst, Sridevi Abboy
PURPOSE: To examine the incidence, presentation, and outcome of optic gliomas in children with neurofibromatosis type 1 (NF1) in Southern California Kaiser Permanente. METHODS: The authors queried the Southern California Kaiser Permanente electronic medical record database to find patients diagnosed as having NF1. Genetics, ophthalmology, and imaging medical records of patients with optic glioma were reviewed. RESULTS: A total of 708 patients younger than 21 years had a diagnosis of NF1 in Southern California Kaiser Permanente and 30 (4...
August 18, 2016: Journal of Pediatric Ophthalmology and Strabismus
Dalia Jarusaitiene, Rasa Verkauskiene, Vytautas Jasinskas, Jurate Jankauskiene
Background. Due to low incidence of Graves' ophthalmopathy (GO) among children, the manifestation is poorly analyzed, posing a risk to late identification of insidious disease. Purposes. To identify predictive factors that may influence the development of GO in pediatric and young patients with Graves' disease (GD). Methods. A cross-sectional study of patients newly diagnosed with pediatric or juvenile GD during 2002-2012 was conducted at the Hospital of Lithuanian University of Health Sciences. Ocular evaluation was based on European Group on Graves' Orbitopathy survey...
2016: International Journal of Endocrinology
Lourdes Quintanilla-Dieck, Sivakumar Chinnadurai, Steven L Goudy, Frank W Virgin
OBJECTIVES/HYPOTHESIS: Superior pediatric orbital subperiosteal abscesses (SPAs) are less common than medial ones, and clinical features specific to patients with superior SPAs have not been well defined. Clinical characteristics between patients with superior and medial SPAs are compared to determine whether superior location is a risk factor for surgical intervention. STUDY DESIGN: Retrospective cohort study. METHODS: The target population consisted of patients diagnosed with an SPA and seen by the pediatric otolaryngology service at a tertiary children's hospital between January 2010 and October 2014...
June 12, 2016: Laryngoscope
Hamid Borghei-Razavi, Shunsuke Shibao, Uta Schick
Optic pathway glioma (OPG) encompasses a spectrum of findings ranging from lesions confined to the optic nerve only, lesions affecting the optic chiasm and hypothalamus, and lesions with diffuse involvement of a large part of the optic pathway and neighboring structures. The majority of pediatric low-grade astrocytomas in the optic/chiasmatic region are typical pilocytic astrocytoma. The rest of them (10 %) may be other gliomas such as fibrillary pilomyxoid astrocytoma (grade 2 WHO). The postsurgical local recurrence rate of 55 to 76 % has been reported in some histological subtypes such as pilomyxoid astrocytoma (grade 2)...
May 26, 2016: Neurosurgical Review
Hayyam Kiratli, Irem Koç, Diclehan Orhan
A 15-year-old girl presented with painful proptosis in the right eye. Imaging studies demonstrated an inferiorly located orbital mass. Histopathological examination of the exenteration specimen was consistent with malignant peripheral nerve sheath tumor. This case is a rare example of orbital malignant peripheral nerve sheath tumor presumably arising from the infraorbital nerve with heterologous histologic elements.
2016: Journal of Pediatric Ophthalmology and Strabismus
Abolhasan Ertiaei, Sara Hanaei, Zohreh Habibi, Ehsan Moradi, Farideh Nejat
OBJECTIVE: Optic pathway gliomas (OPG) are infrequent pediatric brain tumors that affect the optic nerve and the visual pathway in the brain. A wide spectrum of signs and symptoms, such as visual impairment, nystagmus, proptosis, and visual loss, may occur at different stages. Other manifestations, such as hydrocephalus, diancephalic syndrome, neurologic deficits, and growth and developmental delays, may be present as well. Surgical resection, chemotherapy, and radiotherapy are used as treatment strategies...
2016: Pediatric Neurosurgery
Eva I Rubio, Anna Blask, Dorothy I Bulas
BACKGROUND: Craniosynostosis syndromes are uncommonly encountered in the prenatal period. Identification is challenging but important for family counseling and perinatal management. OBJECTIVE: This series examines prenatal findings in craniosynostosis syndromes, comparing the complementary roles of US and MRI and emphasizing clues easily missed in the second trimester. MATERIALS AND METHODS: Six prenatal cases evaluated from 2002 through 2011 were retrospectively reviewed...
May 2016: Pediatric Radiology
Leslie A Wei, Tabassum A Kennedy, Sean Paul, Timothy S Wells, Greg J Griepentrog, Mark J Lucarelli
OBJECTIVE: Traumatic orbital encephalocele is a rare but severe complication of orbital roof fractures. We describe 3 cases of orbital encephalocele due to trauma in children. METHODS: Retrospective case series from the University of Wisconsin - Madison and Medical College of Wisconsin. RESULTS: Three cases of traumatic orbital encephalocele in pediatric patients were found. The mechanism of injury was motor vehicle accident in 2 patients and accidental self-inflicted gunshot wound in 1 patient...
2016: Orbit
Chris Y Wu, Victor M Elner, Alon Kahana
Thyroid eye disease (TED) usually has mild manifestations in pediatric patients, and orbital decompression is rarely necessarily. The authors present the clinical course of 3 pediatric patients age 16 or younger at the time of decompression surgery with severe orbitopathy. Case 1 is a 9-year-old prepubertal Asian-American female with Graves' disease and TED who underwent balanced decompression for compressive optic neuropathy. Case 2 is a 14-year-old Caucasian female with Graves' disease and TED who underwent balanced decompression for compressive optic neuropathy, stretch optic neuropathy, and globe subluxation...
October 30, 2015: Ophthalmic Plastic and Reconstructive Surgery
Carolina Mendoza F, Patricia Lacourt R
Graves’ orbitopathy (GO) is rare in pediatric patients, however is the most common extrathyroid manifestation of Graves’ disease (GD), being present in 30-67% of patients. GO is an autoimmune inflammatory disorder involving orbital connective and fatty tissues as well as the extraocular muscles. In children, GO is less common and less severe than in adults. The most common symptoms are upper eyelid retraction, conjunctival injection, and proptosis and periorbital edema. Severe complications include dysthyroid optic neuropathy, corneal ulceration and eyeball subluxation...
August 2015: Revista Médica de Chile
Mohammed A Eldesouky, Molham A Elbakary
PURPOSE: The aim of the study was to review the demographic, clinical, and imaging features of Egyptian patients with orbital metastases. METHODS: The study was a retrospective study of patients with orbital metastatic lesions over the last 15 years. RESULTS: The study included 37 patients. Male patients represented 54.1%. The primary tumor was breast carcinoma in 21.6% of patients, with hepatocellular carcinoma (HCC) in 16.2% and cutaneous malignant melanoma in 13...
2015: Clinical Ophthalmology
Canan Akyüz, Hayyam Kıratlı, Hilal Şen, Burça Aydın, Berçin Tarlan, Ali Varan
BACKGROUND: Studies conducted in recent years have reported promising results regarding the treatment of retinoblastoma with the intra-arterial use of melphalan. In the present study, we intended to report the results of intra-arterial chemotherapy with melphalan (IACT) in the treatment of newly diagnosed or relapsed-refractory retinoblastoma patients at the Department of Pediatric Oncology of Hacettepe University, Ankara, Turkey. MATERIALS AND METHODS: This was a retrospective study of patients with intraocular retinoblastoma who were treated with IACT from December 2011 to May 2014...
2015: Ophthalmologica. Journal International D'ophtalmologie
Kavin Vanikieti, Pisit Preechawat, Anuchit Poonyathalang
Primary optic nerve sheath meningioma (PONSM) is extremely rare among children. We report two cases of pediatric PONSM. The first case was a 12-year-old boy who presented with gradual visual loss of his right eye and was found to be associated with neurofibromatosis type 2. The second case was a 10-year-old boy who presented with gradual proptosis of his left eye with normal visual acuity. Severe visual loss is a common clinical manifestation of pediatric PONSM. Although the visual acuity in the second case was normal, his vision rapidly deteriorated to 20/200...
2015: International Medical Case Reports Journal
Danielle Cullen, Neil Munjal, Hannah Chalal, Sriram Ramgopal, Emir Tas, Selma Witchel
Pericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis...
July 14, 2015: Pediatric Emergency Care
Amanda L Stapleton, Elizabeth C Tyler-Kabara, Paul A Gardner, Carl H Snyderman
OBJECTIVES/HYPOTHESIS: To describe the presentation, treatment, and outcomes of benign fibro-osseous tumors involving the skull base in a pediatric population. METHODS: Retrospective chart review from January 2002 to September 2013 of pediatric patients (ages 0-18 years) who underwent endoscopic endonasal surgery (EES) for benign fibro-osseous tumors involving the skull base. RESULTS: Fourteen patients were identified with an age range of 2...
September 2015: Laryngoscope
Satish Kumar Verma, Gurudutta Satyarthee, Sachin Anil Borkar, Manmohan Singh, Bhawani Shnakar Sharma
Primary intraosseous or ectopic meningioma of the skull is a rare tumor accounting for about 1% of meningioma. Intradiploic meningioma is an extremely rare type of extraneuraxial meningiomas. Intradiploic meningioma of the orbit is extremely rare, and <8 such cases are reported till date in western literature occurring in the pediatric age group. Here the authors present a case of 16-year-old female, who presented with progressive proptosis, with normal vision and was managed successfully surgically. Clinical features, pathophysiology, and surgical management of this rare entity are discussed in the context of pertinent literature...
January 2015: Journal of Pediatric Neurosciences
Guru Dutta Satyarthee, Ashish Suri, Ashok Kumar Mahapatra
Osteoma located in the paranasal sinus is a slow growing benign tumor. It commonly occurs in frontal, ethmoid and maxillary sinuses in the order of frequency. Giant osteoma is very rare in the pediatric population, and only nine cases of giant osteoma are reported till date in the form of isolated case reports. Authors report a giant spheno-ethmoidal osteoma in a 14-year-old boy, who presented with progressive visual impairment and proptosis of the left eye for last 1-year. Total excision was carried out using transcranial extradural approach...
January 2015: Journal of Pediatric Neurosciences
John P O'Neill, Andrew R Harrison, J Douglas Cameron, Ali Mokhtarzadeh
A 64-year-old woman with relapsed acute myelogenous leukemia (AML) undergoing salvage chemotherapy developed rapid onset of right-sided ophthalmoplegia, proptosis, optic neuropathy, and vision loss from 20/30 to hand motions over a 3-hour period on day 4 of her treatment. CT scan of her orbits revealed a superolateral orbital mass and periocular edema. She underwent immediate canthotomy and cantholysis, and lateral orbitotomy with debulking of the mass later the same day. The histopathology was consistent with aggregates of myeloid blasts...
April 7, 2015: Ophthalmic Plastic and Reconstructive Surgery
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