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https://www.readbyqxmd.com/read/28104013/-correlation-between-the-visiting-rate-of-patients-with-allergic-rhinitis-and-airborne-pollen-concentrations-in-beijing-in-recent-3-years
#1
W N Hu, L Zhu, L F Xie, F Z Zhang, M Y Bai, N Wang, Z W Sun
Objective: To evaluate the daily airborne pollen concentrations and visiting rate of patients with allergic rhinitis (AR) and their correlation during 2012-2014 in Beijing. Methods: Daily airborne pollen concentrations (55 998 numbers in total and 549 numbers in average) and its constitution from April to September each year (2012 to 2014) were compared. The number of patients with AR (44 203 in total) who visited the outpatient department of Otorhinolaryngology Head and Neck Surgery, Peking University Third Hospital between January 2012 and December 2014 was analyzed by month...
January 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28102718/vitamin-d-status-aeroallergen-sensitization-and-allergic-rhinitis-a-systematic-review-and-meta-analysis
#2
Zahra Aryan, Nima Rezaei, Carlos A Camargo
PURPOSE: The role of vitamin D status in the etiology of allergic diseases is uncertain. The aim of this study was to investigate the association of vitamin D status with risk of two main outcomes: aeroallergen sensitization and allergic rhinitis (AR). METHODS: We performed a systematic review of Medline, Scopus, Science Citation Index, and Google Scholar databases. Studies were included if they reported on prevalent or incident cases of aeroallergen sensitization or AR according to vitamin D status...
January 19, 2017: International Reviews of Immunology
https://www.readbyqxmd.com/read/28102062/the-role-of-il-17-in-a-lipopolysaccharide-induced-rhinitis-model
#3
Jun Sang Bae, Ji Hye Kim, Eun Hee Kim, Ji Hun Mo
PURPOSE: Lipopolysaccharide (LPS) is a cell wall component of Gram-negative bacteria and important for pro-inflammatory mediators. This study aimed to establish a rhinitis model using ovalbumin (OVA) and LPS in order to evaluate the role of interleukin (IL)-17 in the pathogenesis of an LPS-induced non-eosionophilic rhinitis model. METHODS: Mice were divided into 4 groups and each group consisted of 10 mice (negative control group, allergic rhinitis model group, 1-μg LPS treatment group, and 10-μg LPS treatment group)...
March 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28102058/neonatal-immune-state-is-influenced-by-maternal-allergic-rhinitis-and-associated-with-regulatory-t-cells
#4
Lu Tan, Jing Ou, Zezhang Tao, Yonggang Kong, Yu Xu
PURPOSE: Maternal influences contribute to the origin of allergic diseases, but the mechanisms are not clear. The current literature prompted the role of epigenetics in the development of allergic diseases. We sought to investigate the roles of regulatory T (Treg) cells and Forkhead box p3 (Foxp3) DNA methylation in the process of maternal transmission of allergic rhinitis (AR) susceptibility. METHODS: BALB/c female mice (AR mother) were sensitized by intraperitoneal injection of Dermatophagoides pteronyssinus (Der p) 1 on day 1 and 7...
March 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28101683/allergy-histamine-and-antihistamines
#5
Martin K Church
This chapter concentrates on the role in allergic disease of histamine acting on H1-receptors. It is clear that allergy has its roots in the primary parasite rejection response in which mast cell-derived histamine creates an immediate hostile environment and eosinophils are recruited for killing. This pattern is seen in allergic rhinitis where the early events of mucus production and nasal itching are primarily histamine mediated whereas nasal blockage is secondary to eosinophil infiltration and activation...
January 19, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28100959/hydrogen-rich-saline-attenuates-eosinophil-activation-in-a-guinea-pig-model-of-allergic-rhinitis-via-reducing-oxidative-stress
#6
Shaoqing Yu, Chuanliang Zhao, Na Che, Lin Jing, Rongming Ge
BACKGROUND: It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute to elevating oxidative stress. Hydrogen, emerging as a novel antioxidant, has been proven effective in selectively reducing ROS in animals models of oxidative damage. We herein aim to verify protective effects of hydrogen on eosinophils cells in guinea pigs models of AR...
2017: Journal of Inflammation
https://www.readbyqxmd.com/read/28098165/combination-of-mometasone-furoate-and-oxymetazoline-for-the-treatment-of-adenoid-hypertrophy-concomitant-with-allergic-rhinitis-a-randomized-controlled-trial
#7
Wenlong Liu, Lifeng Zhou, Qingxiang Zeng, Renzhong Luo
In the clinic, approximately 30% of children with adenoid hypertrophy (AH) concomitant with allergic rhinitis (AR) report poor responses to intranasal steroids. To determine whether the combination of mometasone furoate (MF) and oxymetazoline (OXY) is more effective than either agent alone, we performed a two-stage, parallel, randomized, double-blind, double-dummy, clinical trial with 240 AH children with concomitant perennial AR. During the first stage, all children were randomly assigned to the MF or control group for six weeks of treatment...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28096738/clinical-management-expectations-and-satisfaction-of-patients-with-moderate-to-severe-allergic-rhinoconjunctivitis-treated-with-sq-standardized-grass-allergen-tablet-under-routine-clinical-practice-conditions-in-spain
#8
Tomás Chivato, Pedro Álvarez-Calderón, Carmen Panizo, Ricardo Abengozar, César Alías, Ali Al-Baech, José Arias-Irigoyen, M José Caballero, Lluis Conill, Silvia de Miguel, Rafael Laguna, Joan Martínez-Benazet, Francisco Matoses, Jose Camilo Martínez-Alonso, Lourdes Mendizábal, Celsa Pérez-Carral, Carlos Puerto, Joan Serra-Batllés, Adolfo Vélez, Jonathan Vicente, Fernando de la Torre
BACKGROUND: Sublingual immunotherapy has been proven as a well-tolerated and effective treatment for allergic rhinitis. Within this type of treatment, GRAZAX(®) is the most documented product in terms of safety and efficacy. The objective of this study was to identify the patients' expectations and level of treatment satisfaction, as well as the clinical management of patients with moderate/severe allergic rhinoconjunctivitis treated with GRAZAX(®). METHODS: This was a non-interventional, observational, multi-centre, open-label study involving a total of 131 adult patients aged 18-66 years with confirmed diagnosis of grass-allergy and initiated treatment with GRAZAX(®) between June 2010 and April 2011...
2017: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/28091681/microbial-rrna-sequencing-analysis-of-evaporative-cooler-indoor-environments-located-in-the-great-basin-desert-region-of-the-united-states
#9
Angela R Lemons, Mary Beth Hogan, Ruth A Gault, Kathleen Holland, Edward Sobek, Kimberly A Olsen-Wilson, Yeonmi Park, Ju-Hyeong Park, Ja Kook Gu, Michael L Kashon, Brett J Green
Recent studies conducted in the Great Basin Desert region of the United States have shown that skin test reactivity to fungal and dust mite allergens are increased in children with asthma or allergy living in homes with evaporative coolers (EC). The objective of this study was to determine if the increased humidity previously reported in EC homes leads to varying microbial populations compared to homes with air conditioners (AC). Children with physician-diagnosed allergic rhinitis living in EC or AC environments were recruited into the study...
January 16, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28087907/-effect-of-methyleugenol-on-expression-of-muc5ac-in-nasal-mucosa-of-rats-with-allergic-rhinitis
#10
Nannan Meng, Yun Hou, Yan Gui, Kehu Xi, Youhu Wang, Jing Yang, Hong Chen, Xiaobing Zhang
Objective: To investigate the effect of methyleugenol on expression of MUC5AC in nasal mucosa of rats with allergic rhinitis (AR). Methods: Seventy-two Wistar rats were randomly divided into 6 groups:normal control group, AR group, loratadine group, low-dose methyleugenol group, middle-dose methyleugenol group and high-dose methyleugenol group with 12 rats in each group. AR was induced by intraperitoneal injection of ovalbumin in latter 5 groups. 10 mg loratadine q.d was given to rats in loratadine group by gavage; and 10 mg/kg, 20 mg/kg and 40 mg/kg methyleugenol were given by gavege q...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28078863/nasal-irrigation-with-nasir%C3%A2-in-children-a-preliminary-experience-on-nasal-cytology
#11
M Gelardi, S Taliente, K Piccininni, G Silvestre, N Quaranta, G Ciprandi
Allergic rhinitis (AR) and upper airway respiratory infections are frequent in children, and both have a relevant impact on some social aspects, including school attendance and performance, sleep, quality of life (also of the parents), and costs. Saline nasal irrigation is widely employed to reduce nasal congestion and mucopurulent secretion, to stimulate cleansing of the nasal and paranasal cavities, and to induce restoration of mucociliary clearance. The present study evaluated the effects of nasal irrigation on nasal cytology, using the new device Nasir® in 66 children (40 males, 26 females, mean age 7...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28074172/non-allergic-rhinitis-in-children-epidemiological-aspects-pathological-features-diagnostic-methodology-and-clinical-management
#12
REVIEW
Dimitri Poddighe, Matteo Gelardi, Amelia Licari, Michele Miraglia Del Giudice, Gian Luigi Marseglia
Chronic rhinitis is a very common disease, as the prevalence in the general population resulted to be 40%. Allergic rhinitis has been considered to be the most frequent form of chronic rhinitis, as non-allergic rhinitis has been estimated to account for 25%. However, several evidences suggested that non-allergic rhinitis have been underrated, especially in children. In pediatrics, the diagnostic definition of non-allergic rhinitis has been often limited to the exclusion of an allergic sensitization. Actually, local allergic rhinitis has been often misdiagnosed as well as mixed rhinitis has not been recognized in most cases...
December 26, 2016: World Journal of Methodology
https://www.readbyqxmd.com/read/28073613/effect-of-nasal-allergen-challenge-in-allergic-rhinitis-on-mitochondrial-function-of-peripheral-blood-mononuclear-cells
#13
Shanshan Qi, Cindy Barnig, Anne-Laure Charles, Anh Poirot, Alain Meyer, Raphaël Clere-Jehl, Fréderic de Blay, Bernard Geny
No abstract text is available yet for this article.
January 7, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28072463/pilot-study-of-mobile-phone-technology-in-allergic-rhinitis-in-european-countries-the-mask-rhinitis-study
#14
J Bousquet, D P Caimmi, A Bedbrook, M Bewick, P W Hellings, P Devillier, S Arnavielhe, C Bachert, K C Bergmann, G W Canonica, N Chavannes, A A Cruz, R Dahl, P Demoly, G De Vries, E Mathieu-Dupas, A Fink Wagner, J Fonseca, N Guldemond, T Haahtela, B Hellqvist-Dahl, J Just, T Keil, L Klimek, M L Kowalski, M Kuitunen, P Kuna, V Kvedariene, D Laune, A M Pereira, P Carreiro-Martins, E Melén, M Morais-Almeida, J Mullol, A Muraro, R Murray, L Nogueira-Silva, N G Papadopoulos, G Passalacqua, F Portejoie, D Price, D Ryan, B Samolinski, A Sheikh, V Siroux, O Spranger, A Todo Bom, P V Tomazic, A Valero, E Valovirta, A Valiulis, O VandenPlas, S van der Meulen, M van Eerd, M Wickman, T Zuberbier
BACKGROUND: The use of Apps running on smartphones and tablets profoundly affects medicine. The MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) App (Allergy Diary) assesses allergic rhinitis symptoms, disease control and impact on patients' lives. It is freely available in 20 countries (iOS and Android platforms). AIMS: To assess in a pilot study whether (i) Allergy Diary users were able to properly provide baseline characteristics (ii) simple phenotypic characteristics based upon data captured by the Allergy Diary could be identified and (iii) information gathered by this study could suggest novel research questions...
January 10, 2017: Allergy
https://www.readbyqxmd.com/read/28066101/comparison-of-efficacy-safety-and-cost-effectiveness-of-montelukast-levocetirizine-and-montelukast-fexofenadine-in-patients-of-allergic-rhinitis-a-randomized-double-blind-clinical-trial
#15
Mohini Sachin Mahatme, Ganesh Natthuji Dakhale, Kanchan Tadke, Sachin Keshaorao Hiware, S D Dudhgaonkar, Sumit Wankhede
OBJECTIVES: Allergic rhinitis (AR) is a global health problem. Almost 10%-25% of population worldwide is affected by AR. Oral/intranasal H1-antihistamine, decongestants, leukotriene receptor antagonists, and intranasal corticosteroids are the pillars in the management of AR. The combination therapy of montelukast with antihistaminic provides enhancing and complimentary effects, thereby reducing the symptoms effectively, but there are scanty data regarding the comparisons of combinations...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28065341/allergen-immunotherapy-for-a-teenager-with-seasonal-allergic-rhinitis-due-to-grass-pollen-subcutaneous-or-sublingual-route
#16
REVIEW
Harold S Nelson, Stephen R Durham
No abstract text is available yet for this article.
January 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28065336/sublingual-immunotherapy-dosing-regimens-what-is-ideal
#17
Jay J Jin, James T Li, Ludger Klimek, Oliver Pfaar
Sublingual immunotherapy (SLIT) is a treatment for allergic respiratory diseases that has demonstrated efficacy and safety. Several formulations of SLIT are now available worldwide for treatment of allergic rhinitis (AR). Grass tablets containing 15 to 25 μg of group 5 major allergen reduced combined AR symptoms and medication use by 23% to 41% in 3 treatment years and 2 follow-up years. Ragweed pollen tablets (12 μg of Ambrosia artemisiifolia 1) and liquid extracts (50 μg of Ambrosia artemisiifolia 1) reduced combined AR symptoms and medication use by 26% and 43%, respectively...
January 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28063043/subcutaneous-and-sublingual-immunotherapy-in-a-mouse-model-of-allergic-asthma
#18
Laura Hesse, Martijn C Nawijn
Allergic asthma, caused by inhaled allergens such as house dust mite or grass pollen, is characterized by reversible airway obstruction, associated with an eosinophilic inflammation of the airways, as well as airway hyper responsiveness and remodeling. The inhaled allergens trigger a type-2 inflammatory response with involvement of innate lymphoid cells (ILC2) and Th2 cells, resulting in high production of immunoglobulin E (IgE) antibodies. Consequently, renewed allergen exposure results in a classic allergic response with a distinct early and late phase, both resulting in bronchoconstriction and shortness of breath...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28054753/t-helper-2-cytokine-induced-heat-shock-protein-70-secretion-and-its-potential-association-with-allergic-rhinitis
#19
Hyun Jin Min, Kyung Soo Kim, Joo-Heon Yoon, Chang-Hoon Kim, Hyung-Ju Cho
BACKGROUND: Various inflammatory mediators have been found to be involved in the pathogenesis of allergic disease (AR). The role of heat shock proteins in AR has not been studied. The aim of this study was to investigate the levels of heat shock protein 70 (Hsp70) in the nasal lavage fluids of AR patients and controls to elucidate the role of Hsp70 in the pathogenesis of AR. METHODS: Using an enzyme-linked immunosorbent assay, the levels of Hsp70, Hsp90, interleukin (IL)-4, IL-13, and IL-8 in nasal lavage fluid from patients were measured and statistically analyzed...
January 5, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28052339/overview-of-systematic-reviews-in-allergy-epidemiology
#20
REVIEW
Jon Genuneit, Annina M Seibold, Christian J Apfelbacher, George N Konstantinou, Jennifer J Koplin, Stefania La Grutta, Kirsty Logan, Michael R Perkin, Carsten Flohr
BACKGROUND: There is a substantial body of evidence on the epidemiology of allergic conditions, which has advanced the understanding of these conditions. We aimed to systematically identify systematic reviews and meta-analyses on the epidemiology of allergic diseases to assess what has been studied comprehensively and what areas might benefit from further research. METHODS: We searched PubMed and EMBASE up to 12/2014 for systematic reviews on epidemiological research on allergic diseases...
January 4, 2017: Allergy
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