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https://www.readbyqxmd.com/read/28714426/suicide-following-acute-admissions-for-physical-illnesses-across-england-and-wales
#1
S E Roberts, A John, U Kandalama, J G Williams, R A Lyons, K Lloyd
BACKGROUND: The study aim was to establish and quantify suicide risk following acute admissions for all major physical illnesses, for confirmatory purposes, from two independent information sources from different countries. METHODS: Record linkage of inpatient and death certificate data for 11 004 389 acute admissions for physical illnesses in England and 713 496 in Wales. The main outcome measure was standardised mortality ratios (SMRs) for suicide at 1 year following discharge from hospital...
July 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28690533/dysphagia-in-perry-syndrome-pharyngeal-pressure-in-two-cases
#2
George Umemoto, Yoshio Tsuboi, Hirokazu Furuya, Takayasu Mishima, Shinsuke Fujioka, Naoki Fujii, Hajime Arahata, Miwa Sugahara, Mitsuaki Sakai
BACKGROUND: To investigate the impact of dysphagia in Perry syndrome (PS), an autosomal dominant parkinsonism caused by mutation of DCTN1, which is associated with hypoventilation, depression, and weight loss. CASE PRESENTATION: We used tongue pressure measurements and manofluorography to investigate swallowing function in 2 patients with PS. Case 1, a 60-year-old male showing parkinsonism, and case 2, a 49-year-old male admitted with pneumonia, were diagnosed as having PS based on the DCTN1 gene analysis...
May 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/28652714/the-safety-issues-and-hardware-related-complications-of-deep-brain-stimulation-therapy-a-single-center-retrospective-analysis-of-478-patients-with-parkinson-s-disease
#3
Jing Zhang, Tao Wang, Chen-Cheng Zhang, Kristina Zeljic, Shikun Zhan, Bo-Min Sun, Dian-You Li
INTRODUCTION: Deep brain stimulation (DBS) is a well-established therapy for the treatment of advanced Parkinson's disease (PD) in patients experiencing motor fluctuations and medication-refractory tremor. Despite the relative tolerability and safety of this procedure, associated complications and unnatural deaths are still unavoidable. METHODS: In this study, hardware-related complications and the causes of unnatural death were retrospectively analyzed in 478 patients with PD who were treated with DBS...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28560917/caring-for-patients-with-parkinson-s-disease-in-general-hospital-settings
#4
Vicky Queen
Parkinson's disease (PD) is a common progressive neurological condition. There are 127,000 people with the disease in the UK, that is, one in every 500 of the population. In 2014-15 there were 14,000 hospital admissions of people with PD in England. However, PD is often not the primary cause of admission. Urinary tract infections and pneumonia, for example, are frequent causes of hospital admission for people with PD. Therefore, nurses on general medical and surgical wards will often care for people with PD...
May 31, 2017: Nursing Older People
https://www.readbyqxmd.com/read/28473650/a-descriptive-study-of-lewy-body-dementia-with-functional-imaging-support-in-a-chinese-population-a-preliminary-study
#5
Y F Shea, L W Chu, S C Lee
INTRODUCTION: Lewy body dementia includes dementia with Lewy bodies and Parkinson's disease dementia. There have been limited clinical studies among Chinese patients with Lewy body dementia. This study aimed to review the presenting clinical features and identify risk factors for complications including fall, dysphagia, aspiration pneumonia, pressure sores, and mortality in Chinese patients with Lewy body dementia. We also wished to identify any difference in clinical features of patients with Lewy body dementia with and without an Alzheimer's disease pattern of functional imaging...
May 5, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28447217/swallowing-disorders-in-schizophrenia
#6
REVIEW
Deepika P Kulkarni, Vandan D Kamath, Jonathan T Stewart
Disorders of swallowing are poorly characterized but quite common in schizophrenia. They are a source of considerable morbidity and mortality in this population, generally as a result of either acute asphyxia from airway obstruction or more insidious aspiration and pneumonia. The death rate from acute asphyxia may be as high as one hundred times that of the general population. Most swallowing disorders in schizophrenia seem to fall into one of two categories, changes in eating and swallowing due to the illness itself and changes related to psychotropic medications...
August 2017: Dysphagia
https://www.readbyqxmd.com/read/28253409/enhancing-care-for-hospitalized-patients-with-parkinson-s-disease-development-of-a-formal-educational-program-for-nursing-staff
#7
Mary C DiBartolo
Although not generally a primary admission diagnosis, Parkinson's disease (PD) can be a significant comorbidity during hospitalization. Hospitalized individuals with PD can experience a variety of complications, such as confusion, pneumonia, and urinary infections. More than 20% of patients experience deterioration in symptoms and hospital stays are extended by an average of 4 days. Late, omitted, or inappropriate medications are frequent culprits leading to serious consequences, including falls and aspiration...
May 1, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27795943/tailored-deep-brain-stimulation-optimization-for-improved-airway-protective-outcomes-in-parkinson-s-disease
#8
Michelle S Troche, Alexandra E Brandimore, Karen W Hegland, Pamela R Zeilman, Kelly D Foote, Michael S Okun
There is no consensus regarding the effects of deep brain stimulation (DBS) surgery on swallowing outcomes in Parkinson's disease (PD). No prospective studies have compared airway protective outcomes following DBS to the subthalamic nucleus (STN) versus globus pallidus interna (GPi). A recent retrospective study described swallowing outcomes pre- and post-STN vs. GPi DBS in a cohort of 34 patients with PD. The results revealed that the patients who received GPi DBS maintained their swallowing function post-DBS, while those in the STN group significantly worsened in swallowing safety...
September 2016: Interdisciplinary Neurosurgery: Advanced Techniques and Case Management
https://www.readbyqxmd.com/read/27662326/acute-hospital-admissions-of-individuals-with-a-known-parkinson-s-disease-diagnosis-in-ireland-2009-2012-a-short-report
#9
Bróna Kelly, Catherine Blake, Olive Lennon
BACKGROUND: The rate of people with Parkinson's disease (PD) is predicted to double by 2030 resulting in an even greater burden to an already struggling Irish health care system. There is a paucity of information regarding hospital utilisation among the PD population in an Irish context. OBJECTIVE: To examine trends of acute hospital in-patient admissions of patients admitted with a secondary diagnosis of PD between 2009 and 2012 in Ireland. METHOD: Data concerning patients, aged over and under 65 years with a previously existing diagnosis of Parkinson's Disease were requested from the HIPE database for the years 2009-2012...
October 19, 2016: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/27649015/-hospital-mortality-in-parkinson-s-disease-retrospective-analysis-in-a-portuguese-tertiary-centre
#10
Joana Martins, Adriana Rua, Nuno Vila Chã
INTRODUCTION: Parkinson's disease is associated with high hospital mortality. Male gender, late age at onset, higher disability and the coexistence of cognitive impairment or depression have been suggested to be risk factors of death. Pneumonia and cardiovascular diseases are the leading causes of death. OBJECTIVE: To characterize the mortality (causes of hospital admission and death) of Parkinson's disease patients in a tertiary hospital, as well as demographic and clinical characteristics...
May 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27533053/premotor-symptoms-as-predictors-of-outcome-in-parkinsons-disease-a-case-control-study
#11
Yu-Hsuan Wu, Wei-Ju Lee, Yi-Huei Chen, Ming-Hong Chang, Ching-Heng Lin
BACKGROUND: To evaluate the association between the premotor symptoms and the prognosis of PD. METHODS: A total of 1213 patients who were diagnosed of PD from January 2001 to December 2008 were selected from the Taiwan's National Health Insurance Research Database. Patients were traced back to determine the presence of premotor symptoms, including rapid eye movement sleep behavior disorder (RBD), depression, and constipation. Cox's regression analysis was used to detect the risks between the occurrence of premotor symptoms and the outcome (including death, psychosis, accidental injury, dementia and aspiration pneumonia)...
2016: PloS One
https://www.readbyqxmd.com/read/27532657/effectiveness-of-allied-health-therapy-in-the-symptomatic-management-of-progressive-supranuclear-palsy-a-systematic-review
#12
Erica Tilley, James McLoughlin, Simon A Koblar, Sebastian H Doeltgen, Cindy Stern, Sarahlouise White, Micah D J Peters
BACKGROUND: Progressive supranuclear palsy (PSP) is an adult onset neurodegenerative condition associated with mobility, balance, speech, swallowing, vision and cognitive changes. The condition is diagnosed using the National Institute for Neurological Disorders and Stroke (NINDS) and the Society of Progressive Supranuclear Palsy (SPSP) criteria. Therapeutic interventions for PSP are important, and a healthcare team should include a physiotherapist, occupational therapist and speech therapist...
June 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27462817/a-novel-excitatory-network-for-the-control-of-breathing
#13
Tatiana M Anderson, Alfredo J Garcia, Nathan A Baertsch, Julia Pollak, Jacob C Bloom, Aguan D Wei, Karan G Rai, Jan-Marino Ramirez
Breathing must be tightly coordinated with other behaviours such as vocalization, swallowing, and coughing. These behaviours occur after inspiration, during a respiratory phase termed postinspiration. Failure to coordinate postinspiration with inspiration can result in aspiration pneumonia, the leading cause of death in Alzheimer's disease, Parkinson's disease, dementia, and other neurodegenerative diseases. Here we describe an excitatory network that generates the neuronal correlate of postinspiratory activity in mice...
August 4, 2016: Nature
https://www.readbyqxmd.com/read/27461481/reflex-cough-and-disease-duration-as-predictors-of-swallowing-dysfunction-in-parkinson-s-disease
#14
Michelle S Troche, Beate Schumann, Alexandra E Brandimore, Michael S Okun, Karen W Hegland
Patients with Parkinson's disease (PD) have progressive and pervasive disorders of airway protection. Recent work has highlighted the relationship between reflex and voluntary cough and swallowing safety. The goal of this study was to test the sensitivity and specificity of several airway protective and disease-specific factors for predicting swallowing safety outcomes in PD. Sixty-four participants (44 males) completed measures of voluntary and reflex cough, and swallowing safety. Clinical predictors included disease severity and duration, and cough airflow and sensitivity measures...
July 26, 2016: Dysphagia
https://www.readbyqxmd.com/read/27446780/the-functional-dysphagia-scale-is-a-useful-tool-for-predicting-aspiration-pneumonia-in-patients-with-parkinson-disease
#15
Jong Hwa Lee, Kyeong Woo Lee, Sang Beom Kim, Sook Joung Lee, Sang Myung Chun, Sung Moon Jung
OBJECTIVE: To describe the correlation between the functional dysphagia scale and aspiration pneumonia and which characteristics influence the occurrence of aspiration pneumonia in patients with idiopathic Parkinson disease. METHODS: Fifty-three patients with idiopathic Parkinson disease were prospectively evaluated in this study. Disease severity and functional status were measured by modified Hoehn and Yahr (H&Y) staging, Schwab and England activities of daily living (S-E ADL) scale and Korean version of Mini-Mental State Examination (K-MMSE)...
June 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27321989/risk-and-prognostic-factors-for-pneumonia-and-choking-amongst-parkinson-s-disease-patients-with-dysphagia
#16
Kwang-Hwee Goh, Sanchalika Acharyya, Samuel Yong-Ern Ng, Jasmine Pei-Ling Boo, Amanda Hui-Juan Kooi, Hwee-Lan Ng, Wei Li, Kay-Yaw Tay, Wing-Lok Au, Louis Chew-Seng Tan
OBJECTIVE: To evaluate the time to hospitalisation and baseline factors associated with pneumonia/choking in Parkinson's Disease (PD) patients. BACKGROUND: Although dysphagia and pneumonia are common problems in PD, scarce research has been performed. METHODS: A total of 194 PD patients who underwent a VFS evaluation were retrospectively selected. The mode of feeding and admissions for pneumonia/choking were analyzed. Baseline clinical and demographic variables were compared between feeding groups...
August 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/27299944/-dysphagia-in-parkinson-s-disease-pathophysiology-diagnosis%C3%A2-and-therapy
#17
I Suttrup, T Warnecke
Oropharyngeal and esophageal dysphagia are a frequent, but seldom diagnosed symptom of Parkinson's disease (PD). More than 80 % of patients with PD develop dysphagia during the course of their disease leading to a reduced quality of life, complicated medication intake, malnutrition and aspiration pneumonia, which is a major cause of death in PD. The underlying pathophysiology is poorly understood. Impaired dopaminergic and non-dopaminergic mechanisms of the cortical swallowing network as well as peripheral neuromuscular involvement have been suggested to contribute to its multifactorial genesis...
July 2016: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/27276074/-perioperative-management-of-pd-patients
#18
H Reichmann
Both patients and caregivers but also treating physicians are concerned about complications along with surgical interventions. A major problem is abrupt cessation of anti-Parkinson medication, which leads to manifold disturbances, sometimes even to an akinetic crisis. There are several means to guarantee continuous dopaminergic stimulation even in patients that are not allowed to take medication orally before they undergo surgery. Amongst others rectally applied levodopa, amantadine infusions, and especially the use of a rotigotine patch are good means to overcome oral intake...
July 2016: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/27269197/swallowing-disorders-in-parkinson-s-disease
#19
Sandra Mamolar Andrés, María Liliana Santamarina Rabanal, Carla María Granda Membiela, María José Fernández Gutiérrez, Paloma Sirgo Rodríguez, César Álvarez Marcos
INTRODUCTION: Parkinson's disease is a type of chronic neurodegenerative pathology with a typical movement pattern, as well as different, less studied symptoms such as dysphagia. Disease-related disorders in efficacy or safety in the process of swallowing usually lead to malnutrition, dehydration or pneumonias. The aim of this study was identifying and analyzing swallowing disorders in Parkinson's disease. SUBJECTS AND METHODS: The initial sample consisted of 52 subjects with Parkinson's disease to whom the specific test for dysphagia SDQ was applied...
January 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/27242063/epidemiology-of-inpatient-stay-in-parkinson-s-disease-in-the-united-states-insights-from-the-nationwide-inpatient-sample
#20
Abhimanyu Mahajan, Poojitha Balakrishnan, Achint Patel, Ioannis Konstantinidis, Dominic Nistal, Narender Annapureddy, Priti Poojary, Girish N Nadkarni, Christos Sidiropoulos
The total number of people living with Parkinson's disease (PD) worldwide is expected to double by 2030. The risk factors for emergency department visits in PD patients have been described before, however, there is limited data on inpatient hospitalizations of PD patients. We derived our study cohort from the Nationwide Inpatient Sample (NIS) database from 2002-2011. The NIS is a stratified 20% sample of discharges from all U.S. hospitals. We extracted causes of hospitalization using International Classification of Diseases, 9th revision, Clinical Modification (ICD-9-CM) codes and calculated inpatient mortality, length of stay and cost...
September 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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