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https://www.readbyqxmd.com/read/29154448/significance-of-bizarre-cells-in-cervical-screening-liquid-based-cytology-a-prospective-study-of-15-cases
#1
O Ondič, R Ferko, J Kičinová, J Bouda, I Kinkorová-Luňáčková, L Kupcová, M Zůchová, J Chytra, T Waloschek, M Tůmová Bartošková, R Alaghehbandan, J Němcová
OBJECTIVE: The aim of this study was to assess the significance of bizarre cells (cells of squamous origin with a superficial squamous cell-type cytoplasm and characterised by multinucleation that produces bizarre nuclear shapes) in liquid-based cytology (LBC) Papanicoaou (pap) smears with clinical and histological follow-up correlation. METHODS: Fifteen patients, all with LBC samples containing bizarre cells, were identified in routine ThinPrep(®) LBC workload...
November 20, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29153818/expect-the-unexpected-a-bizarre-lookalike-of-left-atrial-tumor
#2
Federico Cammertoni, Piergiorgio Bruno, Christian Colizzi, Biagio Merlino, Natalia Pavone, Marialisa Nesta, Massimo Massetti
No abstract text is available yet for this article.
December 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29151090/de-cl%C3%A3-rambault-syndrome-othello-syndrome-folie-%C3%A3-deux-and-variants
#3
Montserrat G Delgado, Julien Bogousslavsky
Non-bizarre delusion, defined as a false belief possible although highly unlikely, is the main manifestation of delusional disorders, previously known as paranoia. Based on the predominant delusional themes, 5 main subtypes may be described - erotomanic, grandiose, jealous, persecutory, and somatic. We present here 2 main delusional disorders, the De Clérambault syndrome and the Othello syndrome, and another closely related to the previous ones - Folie à deux. In the De Clérambault syndrome, the main delusional theme is erotomanic type, related to passional delirium where the patient has strong sexual feelings towards another person and has the belief that this other person is deeply in love with him or her...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29150427/delayed-encounter-of-parental-genomes-can-lead-to-aneuploidy-in-saccharomyces%C3%A2-cerevisiae
#4
Alan Michael Tartakoff, David Dulce, Elizabeth Landis
We have investigated an extreme deviation from the norm of genome unification that occurs during mating in the yeast, Saccharomyces cerevisiae This deviation is encountered when yeast that carry a mutation of the spindle pole body protein, Kar1, are mated with wildtype cells. In this case, nuclear fusion is delayed and the genotypes of a fraction of zygotic progeny suggest that chromosomes have "transferred" between the parental nuclei in zygotes. This classic yet bizarre occurrence is routinely used to generate aneuploid (disomic) yeast...
November 17, 2017: Genetics
https://www.readbyqxmd.com/read/29138945/glioblastoma-in-neurofibromatosis-1-patients-without-idh1-braf-v600e-and-tert-promoter-mutations
#5
Ichiyo Shibahara, Yukihiko Sonoda, Hiroyoshi Suzuki, Akifumi Mayama, Masayuki Kanamori, Ryuta Saito, Yasuhiro Suzuki, Shoji Mashiyama, Hiroshi Uenohara, Mika Watanabe, Toshihiro Kumabe, Teiji Tominaga
Pilocytic astrocytomas and low-grade gliomas are more common compared with glioblastomas in patients with neurofibromatosis 1 (NF1). A recent genome-wide analysis has shown frequent NF1 gene alterations in the mesenchymal subtype of a glioblastoma; however, little is known about clinicopathological features of glioblastomas in NF1 patients (NF1 glioblastomas). We analyzed four NF1 glioblastomas. Radiographical and intraoperative findings showed well-circumscribed tumors from surrounding brain. Pathological analysis presented a paucity of processes with an eosinophilic cytoplasm, bizarre nuclei, xanthomatous-like appearance, multinucleated giant cells, and histiocytoid appearance...
November 14, 2017: Brain Tumor Pathology
https://www.readbyqxmd.com/read/29137100/ultrasonic-and-pathological-characteristics-of-ovarian-mucinous-cystic-tumors-with-malignant-mural-nodules-two-cases-report
#6
Yan Zhang, Zheng Yuan, Kai Sun, Peifeng Li
RATIONALE: Sarcomatous or anaplastic carcinoma mural nodules presenting in ovarian mucinous cystic tumors are very rare. Here, we reported the ultrasonic and pathological features of 2 such cases. PATIENT CONCERNS: A 60-year-old woman presented with a complaint of lower abdominal pain. Physical examination revealed a hard, palpable mass in her right lower abdomen with mild tenderness. In addition, a 48-year-old woman presented with left abdominal pain and abdominal fullness...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29132723/ovarian-sex-cord-stromal-tumours-and-their-mimics
#7
REVIEW
Robert H Young
Sex cord-stromal tumours of the ovary include many of the most morphologically intriguing ovarian neoplasms and albeit many of them are rare, they factor into the differential diagnosis more often than their frequency might suggest. The most common malignant form, the adult granulosa cell tumour, may grossly simulate various surface epithelial neoplasms. Microscopically, confusion with endometrioid carcinoma may occur because the cords and microfollicles of the granulosa cell tumour may be mimicked by endometrioid carcinoma and the latter may have pale nuclei with nuclear grooves...
November 10, 2017: Pathology
https://www.readbyqxmd.com/read/29118471/cytomorphologic-diversity-of-papillary-thyroid-carcinoma
#8
Vidya Monappa, Ranjini Kudva
Introduction: Cytologic features of papillary thyroid carcinoma (PTC) have been extensively documented in literature. However, PTC variants can prove to be diagnostically challenging on fine needle aspiration cytology (FNAC). Aims: To study the FNAC features of PTC and its variants and explore the causes for misdiagnosis. Materials and Methods: This is a retrospective study. All cases of histopathologically (HP) confirmed cases of PTC during a 2-year period (January 2012 to December 2013) with presurgical FNAC were included...
October 2017: Journal of Cytology
https://www.readbyqxmd.com/read/29111237/imaging-findings-of-primary-hepatic-angiosarcoma-on-gadoxetate-disodium-enhanced-liver-mri-comparison-with-hepatic-haemangiomas-of-similar-size
#9
B Kim, J H Byun, J H Lee, B J Park, H-J Kwon, J H Lee, S J Lee, H J Won, Y M Shin, P N Kim
AIM: To describe imaging characteristics of primary hepatic angiosarcoma on gadoxetate disodium-enhanced dynamic magnetic resonance imaging (MRI) and to determine features that differentiate angiosarcomas from similar-sized haemangiomas. MATERIALS AND METHODS: The study included 15 patients with hepatic angiosarcomas and 35 patients with size-matched hepatic haemangiomas who underwent gadoxetate disodium-enhanced liver MRI. The number, size, growth pattern, signal intensity (SI) characteristics, and SI changes on dynamic scans were evaluated and compared between the two entities...
October 27, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29099806/chromosomal-evolution-in-mole-voles-ellobius-cricetidae-rodentia-bizarre-sex-chromosomes-variable-autosomes-and-meiosis
#10
Sergey Matveevsky, Oxana Kolomiets, Alexey Bogdanov, Mikhayil Hakhverdyan, Irina Bakloushinskaya
This study reports on extensive experimental material covering more than 30 years of studying the genetics of mole voles. Sex chromosomes of Ellobius demonstrate an extraordinary case of mammalian sex chromosomes evolution. Five species of mole voles own three types of sex chromosomes; typical for placentals: XY♂/XX♀; and atypical X0♂/X0♀; or XX♂/XX♀. Mechanisms of sex determination in all Ellobius species remain enigmatic. It was supposed that the Y chromosome was lost twice and independently in subgenera Bramus and Ellobius...
November 3, 2017: Genes
https://www.readbyqxmd.com/read/29084359/self-strangulation-turning-into-partial-hanging-for-a-suicide-victim
#11
Rajanikanta Swain, Mantaran Singh Bakshi, Shivani Dhaka, Krishna Kumar Singh, Asit Kumar Sikary
Hanging is the most common asphyxial method of suicide, whereas suicide by strangulation is unusual. Here, we are reporting a particular methodology of the asphyxial method of suicide in which a case of self-strangulation culminated into partial hanging. A 30-year-old male wrapped one end of the cable wire around his neck. He then passed the other end over a curtain rod and tied that end around the right hand. He pulled the hand down, using the curtain rod as a fulcrum, to tighten the noose around the neck in an attempt to strangulate himself...
October 30, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29074331/intra-individual-variability-and-psychotic-like-experiences-in-adolescents-findings-from-the-alspac-cohort
#12
Simon Wallace, Richard J Linscott
Clinical and epidemiological studies have demonstrated associations between elevated intra-individual variability (IIV) of reaction time and psychotic disorders. However, little attention has been paid to the relationship between performance stability and psychotic-like experiences (PLE) in adolescence, before psychotic disorder onset. Data from 6702 children from the Avon Longitudinal Study of Parents and Children (ALSPAC) were used to address this issue. Children took part in a semi-structured clinical interview regarding psychotic symptoms at age 12 and 18, and reaction time variability was assessed at age 13 and 15...
October 24, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29074230/a-novel-differential-susceptibility-framework-for-the-study-of-nightmares-evidence-for-trait-sensory-processing-sensitivity
#13
REVIEW
Michelle Carr, Tore Nielsen
Research on nightmares has largely focused on the nightmare itself and its associated negative consequences, framing nightmare sufferers as victims of a diathesis-stress induced form of psychopathology. However, there is evidence that frequent nightmare recallers are sensitive to a wide range of sensory and emotional experiences, and report vivid, bizarre and even intensely positive dream and daydream experiences. We propose sensory processing sensitivity as a novel trait marker that underlies the unique symptoms and imaginative richness found in nightmare-prone individuals...
December 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29071265/freezing-fort-knox-mesenteric-carcinoid-cryoablation
#14
Erik Soule, Arya Bagherpour, Jerry Matteo
BACKGROUND: Neuroendocrine malignancy is indolent, yet relentless in its propensity to metastasize to the liver, where it may cause bizarre paraneoplastic syndromes. The pathophysiologic mechanism behind this predilection for hepatic metastasis is twofold: the portal venous system drains the most likely primary sites for neuroendocrine tumors, and the relatively immunosuppressed environment within the hepatic parenchyma is permissive for tumor growth. The standard of care for patients with metastatic neuroendocrine tumor is surgical resection of at least 90% of the tumor burden...
September 2017: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/29064946/synthetic-cannabinoids-a-review-of-the-clinical-implications-of-a-new-drug-of-choice
#15
Shaina A Freund, Adrian S Banning
Synthetic marijuana use is an emerging public health problem in the United States, and can cause agitation, severe psychosis, bizarre hallucinations, and possibly death. This article describes these products, which are unregulated and can vary widely in composition, and how clinicians can recognize patients with synthetic cannabinoid toxicity and treat them appropriately to minimize morbidity and mortality.
November 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29057913/heterochronic-evolution-explains-novel-body-shape-in-a-triassic-coelacanth-from-switzerland
#16
Lionel Cavin, Bastien Mennecart, Christian Obrist, Loïc Costeur, Heinz Furrer
A bizarre latimeriid coelacanth fish from the Middle Triassic of Switzerland shows skeletal features deviating from the uniform anatomy of coelacanths. The new form is closely related to a modern-looking coelacanth found in the same locality and differences between both are attributed to heterochronic evolution. Most of the modified osteological structures in the new coelacanth have their developmental origin in the skull/trunk interface region in the embryo. Change in the expression of developmental patterning genes, specifically the Pax1/9 genes, may explain a rapid evolution at the origin of the new coelacanth...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29043155/catatonia-as-a-putative-nosological-entity-a-historical-sketch
#17
REVIEW
Gábor Gazdag, Rozalia Takács, Gabor S Ungvari
Kahlbaum was the first to propose catatonia as a separate disease following the example of general paresis of the insane, which served as a model for establishing a nosological entity. However, Kahlbaum was uncertain about the nosological position of catatonia and considered it a syndrome, or "a temporary stage or a part of a complex picture of various disease forms". Until recently, the issue of catatonia as a separate diagnostic category was not entertained, mainly due to a misinterpretation of Kraepelin's influential views on catatonia as a subtype of schizophrenia...
September 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/29033957/reacquisition-of-new-meristematic-sites-determines-the-development-of-a-new-organ-the-cecidomyiidae-gall-on-copaifera-langsdorffii-desf-fabaceae
#18
Renê G S Carneiro, Rosy M S Isaias, Ana S F P Moreira, Denis C Oliveira
The development of gall shapes has been attributed to the feeding behavior of the galling insects and how the host tissues react to galling stimuli, which ultimately culminate in a variable set of structural responses. A superhost of galling herbivores, Copaifera langsdorffii, hosts a bizarre "horn-shaped" leaflet gall morphotype induced by an unidentified species of Diptera: Cecidomyiidae. By studying the development of this gall morphotype under the anatomical and physiological perspectives, we demonstrate the symptoms of the Cecidomyiidae manipulation over plant tissues, toward the cell redifferentiation and tissue neoformation...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29033765/celiac-disease-associated-with-a-benign-granulomatous-mass-demonstrating-self-regression-after-initiation-of-a-gluten-free-diet
#19
Abhinav Tiwari, Himani Sharma, Khola Qamar, Zubair Khan, Umar Darr, Anas Renno, Ali Nawras
Celiac disease is a chronic immune-mediated enteropathy in which dietary gluten induces an inflammatory reaction predominantly in the duodenum. Celiac disease is known to be associated with benign small bowel thickening and reactive lymphadenopathy that often regresses after the institution of a gluten-free diet. A 66-year-old male patient with celiac disease presented with abdominal pain and diarrheal illness. Computerized tomography of the abdomen revealed a duodenal mass. Endoscopic ultrasound-guided fine needle aspiration of the mass revealed bizarre stromal cells which represent a nonspecific tissue reaction to inflammation...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29020721/artefact-mimicking-torsades-treat-the-patient-not-the-ecg
#20
Una Bergin, Richard M Lynch
ECG interpretation is an essential skill in the management of the acutely unwell patient and in addition to history taking and physical examination has been shown to have a significant effect on referral patterns to cardiologists. One of the basic initial steps in ECG interpretation is assessment for the presence of artefact which if present can dramatically influence the diagnosis. The most common sources of artefact are tremor e.g. in Parkinson’s disease, loose skin electrodes and electromagnetic interference from other medical devices and mobile phones...
February 2017: Practitioner
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