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https://www.readbyqxmd.com/read/28329458/type-iv-total-anomalous-pulmonary-venous-connection
#1
James D St Louis, Elizabeth M Turk, Jeffrey P Jacobs, James E O'Brien
BACKGROUND: Mortality associated with correction of type IV total anomalous pulmonary venous connection (TAPVC) is generally reported in combination with other anatomic types. The objective of this study is to review surgical outcomes associated with the repair of type IV TAPVC by analyzing a multi-institutional cohort specific for this group. We also analyze patient-specific variables that may contribute to poor operative outcomes. METHODS: A retrospective review of the Pediatric Cardiac Care Consortium (PCCC) registry identified patients who underwent repair of type IV TAPVC between 1982 and 2007...
March 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28320532/atypical-histiocytosis-in-red-squirrels-sciurus-vulgaris
#2
S H Smith, K Stevenson, J Del-Pozo, S Moss, A Meredith
Four red squirrels (Sciurus vulgaris) were subjected to necropsy examination over a 3-year period as part of a broader surveillance study. The squirrels presented with cutaneous, subcutaneous and/or internal swellings and nodules that consisted microscopically of sheets of atypical round cells and multinucleated giant cells. There was moderate anisokaryosis with rare mitoses. Nuclei ranged from oval to indented or C-shaped and some were bizarre, twisted or multilobulated. Many giant cells also had a bizarre morphology, with anisokaryosis within individual cells...
March 17, 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28319526/anaplastic-variant-of-diffuse-large-b-cell-lymphoma-displays-intricate-genetic-alterations-and-distinct-biological-features
#3
Mingyang Li, Yixiong Liu, Yingmei Wang, Gang Chen, Qiongrong Chen, Hualiang Xiao, Fang Liu, Chubo Qi, Zhou Yu, Xia Li, Linni Fan, Ying Guo, Qingguo Yan, Shuangping Guo, Zhe Wang
Anaplastic diffuse large B-cell lymphoma (A-DLBCL) is a rare morphologic variant characterized by the presence of polygonal, bizarre-shaped tumor cells. However, the clinicopathologic and genetic features of this variant are largely unknown. In this study, we investigated 35 cases of A-DLBCL with regard to their clinical, pathologic, and genetic characteristics. The age of the patients ranged from 23 to 89 years (median age, 62 y) with a male to female ratio of 23:12. Twenty-two of 26 (85%) patients had Ann Arbor stage III or IV disease, and 17/26 (65%) patients had a high-intermediate or high International Prognostic Index score...
March 17, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28315695/an-unusual-primary-malignant-tumor-of-the-stomach-fetal-gut-like-gastric-adenocarcinoma-with-blastoma-like-component
#4
Altaf Taher, Nebojsa Denic, Sangeetha N Kalimuthu, Runjan Chetty
An unusual case of a polypoid, malignant gastric tumor in a 62-year man is presented. Endoscopy and subsequent polypectomy revealed an 8.5 x 6.5 x 4.5cm lesion in the body of the stomach. Microscopy showed surface dysplasia with an invasive adenocarcinoma displaying prominent tubulopapillary areas composed of large vacuolated cells, pleomorphic nuclei and occasional cytoplasmic hyaline globules. This component then blended with tubular structures lined by more primitive appearing vacuolated cells embedded within a stroma made up of cellular primitive, high-grade blastema-like areas and, less cellular more pleomorphic foci with spindle and several bizarre, large cells...
March 15, 2017: Human Pathology
https://www.readbyqxmd.com/read/28296914/evolutionary-and-natural-history-of-the-turtle-frog-myobatrachus-gouldii-a-bizarre-myobatrachid-frog-in-the-southwestern-australian-biodiversity-hotspot
#5
Samantha Vertucci, Mitzy Pepper, Danielle L Edwards, J Dale Roberts, Nicola Mitchell, J Scott Keogh
Southwest Australia (SWA) is a global biodiversity hotspot and a centre of diversity and endemism for the Australo-Papuan myobatrachid frogs. Myobatrachus gouldii (the turtle frog) has a highly derived morphology associated with its forward burrowing behaviour, largely subterranean habit, and unusual mode of reproduction. Its sister genera Metacrinia and Arenophryne have restricted distributions in Western Australia with significant phylogeographic structure, leading to the recent description of a new species in the latter...
2017: PloS One
https://www.readbyqxmd.com/read/28295234/adverse-drug-reactions-in-children-the-double-edged-sword-of-therapeutics
#6
Abdelbaset A Elzagallaai, Michael J E Greff, Michael J Rieder
Adverse drug reactions (ADRs) represent a major health problem worldwide with high morbidity and mortality rates. ADRs are classified into type A (augmented) and type B (bizarre) ADRs with the former group being more common and the later less common but often severe and clinically more problematic due to their unpredictable nature and occurrence at any dose. Pediatric populations are especially vulnerable to ADRs due to the lack of data for this age group from the drug development process and because of the wide use of Off-label and unlicensed use of drugs...
March 13, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28292639/oculomotor-prediction-a-window-into-the-psychotic-mind
#7
REVIEW
Katharine N Thakkar, Vaibhav A Diwadkar, Martin Rolfs
Psychosis - an impaired contact with reality - is a hallmark of schizophrenia. Many psychotic symptoms are associated with disruptions in agency - the sense that 'I' cause my actions. A failure to predict sensory consequences of one's own actions may underlie agency disturbances. Such predictions rely on corollary discharge (CD) signals, 'copies' of movement commands sent to sensory regions prior to action execution. Here, we make a case that the oculomotor system is a promising model for understanding CD in psychosis, building on advances in our understanding of the behavioral and neurophysiological correlates of CD associated with eye movements...
March 11, 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/28290977/actinomyces-related-tubo-ovarian-abscess-in-a-poorly-controlled-type-ii-diabetic-with-a-copper-intrauterine-device
#8
Ashley L Sawtelle, Nicole P Chappell, Caela R Miller
BACKGROUND: The historic association of Actinomyces israelii infection with intrauterine devices (IUDs) has long been recognized. In recent years, the risk of developing pelvic inflammatory disease with a copper or levonorgestrel IUD has been less than 1% in women who are low risk for sexually transmitted infections. IUD-related pelvic infections secondary to actinomyces have largely vanished from contemporary practice. CASE: A 49-year-old using a copper IUD for contraception with poorly controlled type II diabetes mellitus was admitted for suspected tubo-ovarian abscess on the basis of abdominopelvic pain, leukocytosis, and computed tomography findings...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28271635/a-case-of-ovarian-steroid-cell-tumor-with-bizarre-nuclear-atypia-and-ctnnb1-mutation
#9
Masaki Suzuki, Jun Matsushima, Takuya Yazawa, Satoshi Ota, Takako Kiyokawa, Hiroki Sonehara, Shinsuke Hanawa, Akira Mitsuhashi, Makio Shozu, Yukio Nakatani
No abstract text is available yet for this article.
March 8, 2017: Pathology International
https://www.readbyqxmd.com/read/28268143/a-case-report-of-heel-pain-mimicking-plantar-fasciitis-and-osteosarcoma-a-unique-presentation-of-a-nora-s-lesion
#10
Calvin J Rushing, Diana E Rogers, Steven M Spinner, David C Gajzer
Bizarre parosteal osteochondromatous proliferation, otherwise known as "Nora's lesion," is a rare benign neoplasm first described by Nora in 1983. The exact etiology of this neoplasm remains unknown, and its presentation in the lower extremity presents a diagnostic challenge, as both clinical and radiologic features cannot fully differentiate it from other neoplasms. We present the case of a 48-year-old female with plantar heel pain secondary to Nora's lesion mimicking plantar fasciitis and periosteal osteosarcoma...
March 3, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28258476/psychomotor-agitation-following-treatment-with-hydroxychloroquine
#11
Ciro Manzo, Pietro Gareri, Alberto Castagna
We describe the case of an elderly woman with elderly-onset rheumatoid arthritis, where the use of 4 mg/kg/day of hydroxychloroquine (HCQ) was followed by the onset of psychomotor agitation with marked physical and verbal violence towards her partner, including throwing objects at her partner. No disturbance in sleep and no anxiety, nervousness, or irritability had emerged before the onset of her psychomotor agitation. The disappearance of agitation following targeted pharmacologic intervention and HCQ interruption, its re-onset after reintroduction of the drug, and the high score (9) of Naranjo's algorithm are surely linked to the existence of a causal relationship between HCQ and psychomotor agitation...
December 2017: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/28255150/computed-tomography-of-the-thorax-with-3d-reconstruction-in-penetrating-chest-injury
#12
A Michael, Z O Yahya, I Mdrazali, H Hanif
Penetrating chest wounds is less common but more deadly then blunt trauma. Majority of penetrating chest trauma can be managed conservatively with observation and simple thoracotomy. This case report highlights a bizarre occupational hazard causing a penetrating chest injury and the option of non-invasive management with the aid of computed tomography with 3D reconstruction.
February 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28242485/cardiac-myxoma-report-of-a-case-with-bizarre-histiocytic-infiltration
#13
Deepika Savant, Leonard Kahn
No abstract text is available yet for this article.
February 14, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28241059/exceptionally-prolonged-tooth-formation-in-elasmosaurid-plesiosaurians
#14
Benjamin P Kear, Dennis Larsson, Johan Lindgren, Martin Kundrát
Elasmosaurid plesiosaurians were globally prolific marine reptiles that dominated the Mesozoic seas for over 70 million years. Their iconic body-plan incorporated an exceedingly long neck and small skull equipped with prominent intermeshing 'fangs'. How this bizarre dental apparatus was employed in feeding is uncertain, but fossilized gut contents indicate a diverse diet of small pelagic vertebrates, cephalopods and epifaunal benthos. Here we report the first plesiosaurian tooth formation rates as a mechanism for servicing the functional dentition...
2017: PloS One
https://www.readbyqxmd.com/read/28240187/the-endocannabinoid-system-modulating-levels-of-consciousness-emotions-and-likely-dream-contents
#15
Eric Murillo-Rodriguez, José Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cruz
Cannabinoids are derivatives that are either compounds occurring naturally in the plant, Cannabis sativa or synthetic analogs of these molecules. The first and most widely investigated of the cannabinoids is ∆9-tetrahydrocannabinol (Δ9-THC), which is the main psychotropic constituent of cannabis and undergoes significant binding to cannabinoid receptors. These cannabinoid receptors are seven-transmembrane receptors that received their name from the fact that they respond to cannabinoid compounds, including Δ9-THC...
February 23, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28223752/a-case-of-terra-firma-forme-dermatosis-treated-with-salicylic-acid-alcohol-peeling
#16
Sin Wook Chun, Suk Young Lee, Jong Baik Kim, Hoo Min Choi, Byung In Ro, Han Kyoung Cho
Terra firma-forme dermatosis (TFFD) is a bizarre, acquired and idiopathic dermatosis that etiology has still not been fully defined. It is characterized by the presence of asymptomatic, brownish dirt-like lesion maybe due to disorder of keratinization. These lesions cannot be removed with ordinary cleansing. Therefore, TFFD can be differentiated from dermatosis neglecta. Patient was a 17-year-old man with brownish lesions on his face for 1 month. The patient had a history of regular washing habit with soap and water...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28215361/osteochondroma-of-the-tibial-sesamoid-a-case-report-and-review-of%C3%A2-the-literature
#17
Kazuo Ouchi, Michiyuki Hakozaki, Shin-Ichi Kikuchi, Shoji Yabuki, Shin-Ichi Konno
Osteochondroma, one of the most common benign bone tumors, frequently occurs in the metaphysis of the long bones. We report an extremely rare case of osteochondroma that occurred in the tibial sesamoid. The patient was a 62-year-old Japanese male. He presented with a 1-year history of pain and a hard mass on the plantar aspect of the right forefoot sole. The osteochondroma protruded toward the sole from the tibial sesamoid, leading to pain on weightbearing. After tibial sesamoidectomy, the patient's symptoms were eliminated, and no pain or complications such as hallux valgus occurred after the surgery...
February 15, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28205345/differential-diagnosis-of-well-differentiated-squamous-cell-carcinoma-from-non-neoplastic-oral-mucosal-lesions-new-cytopathologic-evaluation-method-dependent-on-keratinization-related-parameters-but-not-nuclear-atypism
#18
Hitoshi Hara, Tsuneo Misawa, Eri Ishii, Miki Nakagawa, Saki Koshiishi, Kenji Amemiya, Toshio Oyama, Kazuya Tominaga, Jun Cheng, Akio Tanaka, Takashi Saku
BACKGROUND: The cytology of oral squamous cell carcinoma (SCC) is challenging because oral SCC cells tend to be well differentiated and lack nuclear atypia, often resulting in a false negative diagnosis. The purpose of this study was to establish practical cytological parameters specific to oral SCCs. METHODS: We reviewed 123 cases of malignancy and 53 of non-neoplastic lesions of the oral mucosa, which had been diagnosed using both cytology and histopathology specimens...
February 16, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28197997/children-s-use-of-memory-editing-strategies-to-reject-source-misinformation
#19
Kara N Moore, James M Lampinen, David A Gallo, Eryn J Adams, Ana J Bridges
This is the first reported study of children's use of two metacognitive strategies, recollection rejection and diagnostic monitoring, to reject misinformation. Recollection rejection involves the retrieval of details that disqualify an event, whereas diagnostic monitoring involves the failure to retrieve expected details. First (n = 56, age 7 years) and third graders (n = 52, age 9 years) witnessed a staged classroom interaction involving common and bizarre accidents, were presented with misinformation about the source of these events, and took a memory test...
February 15, 2017: Child Development
https://www.readbyqxmd.com/read/28191025/from-egg-to-no-body-an-overview-and-revision-of-developmental-pathways-in-the-ancient-arthropod-lineage-pycnogonida
#20
REVIEW
Georg Brenneis, Ekaterina V Bogomolova, Claudia P Arango, Franz Krapp
BACKGROUND: Arthropod diversity is unparalleled in the animal kingdom. The study of ontogeny is pivotal to understand which developmental processes underlie the incredible morphological disparity of arthropods and thus to eventually unravel evolutionary transformations leading to their success. Work on laboratory model organisms has yielded in-depth data on numerous developmental mechanisms in arthropods. Yet, although the range of studied taxa has increased noticeably since the advent of comparative evolutionary developmental biology (evo-devo), several smaller groups remain understudied...
2017: Frontiers in Zoology
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