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High Density mapping

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https://www.readbyqxmd.com/read/28821300/t1-refblochi-high-resolution-3d-post-contrast-t1-myocardial-mapping-based-on-a-single-3d-late-gadolinium-enhancement-volume-bloch-equations-and-a-reference-t1
#1
Chenxi Hu, Albert J Sinusas, Steffen Huber, Stephanie Thorn, Mitchel R Stacy, Hamid Mojibian, Dana C Peters
BACKGROUND: High resolution 3D T1 mapping is important for assessment of diffuse myocardial fibrosis in left atrium or other thin-walled structures. In this work, we investigated a fast single-TI 3D high resolution T1 mapping method that directly transforms a 3D late gadolinium enhancement (LGE) volume to a 3D T1 map. METHODS: The proposed method, T1-refBlochi, is based on Bloch equation modeling of the LGE signal, a single-point calibration, and assumptions that proton density and T2* are relatively uniform in the heart...
August 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28821183/improvement-of-the-threespine-stickleback-genome-using-a-hi-c-based-proximity-guided-assembly
#2
Catherine L Peichel, Shawn T Sullivan, Ivan Liachko, Michael A White
Scaffolding genomes into complete chromosome assemblies remains challenging even with the rapidly increasing sequence coverage generated by current next-generation sequence technologies. Even with scaffolding information, many genome assemblies remain incomplete. The genome of the threespine stickleback (Gasterosteus aculeatus), a fish model system in evolutionary genetics and genomics, is not completely assembled despite scaffolding with high-density linkage maps. Here, we first test the ability of a Hi-C based proximity-guided assembly (PGA) to perform a de novo genome assembly from relatively short contigs...
September 1, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/28819820/genome-wide-characterization-of-the-wrky-gene-family-in-radish-raphanus-sativus-l-reveals-its-critical-functions-under-different-abiotic-stresses
#3
Bernard Kinuthia Karanja, Lianxue Fan, Liang Xu, Yan Wang, Xianwen Zhu, Mingjia Tang, Ronghua Wang, Fei Zhang, Everlyne M'mbone Muleke, Liwang Liu
The radish WRKY gene family was genome-widely identified and played critical roles in response to multiple abiotic stresses. The WRKY is among the largest transcription factors (TFs) associated with multiple biological activities for plant survival, including control response mechanisms against abiotic stresses such as heat, salinity, and heavy metals. Radish is an important root vegetable crop and therefore characterization and expression pattern investigation of WRKY transcription factors in radish is imperative...
August 17, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28819756/nanofibers-grafted-on-titanium-alloy-the-effects-of-fiber-alignment-and-density-on-osteoblast-mineralization
#4
Hsin-Yi Lin, Zhao-Xiang Peng
The surface of medical implant alloy Ti-6Al-4V was chemically modified to allow it to covalently bond with collagen/PVA nanofibers. These nanofibers were successfully attached to the Ti-6Al-4V surface in three different morphologies: randomly oriented high-density fiber, COL(H); randomly oriented low-density fiber, COL(L); and aligned high-density fiber, COL(A). The effects of the morphology of these covalently-bound collagen nanofibers on the growth and differentiation of osteoblasts were studied for 21 days...
August 17, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28815992/the-spatial-distribution-of-soil-organic-carbon-in-tidal-wetland-soils-of-the-continental-united-states
#5
Audra L Hinson, Rusty A Feagin, Marian Eriksson, Raymond G Najjar, Maria Herrmann, Thomas S Bianchi, Michael Kemp, Jack A Hutchings, Steve Crooks, Thomas Boutton
Tidal wetlands contain large reservoirs of carbon in their soils and can sequester carbon dioxide (CO2 ) at a greater rate per unit area than nearly any other ecosystem. The spatial distribution of this carbon influences climate and wetland policy. To assist with international accords such as the Paris Climate Agreement, national-level assessments such as the United States (U.S.) National Greenhouse Gas Inventory, and regional, state, local, and project-level evaluation of CO2 sequestration credits, we developed a geodatabase (CoBluCarb) and high-resolution maps of soil organic carbon (SOC) distribution by linking National Wetlands Inventory data with the U...
August 17, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28812079/computational-evaluation-of-aluminophosphate-zeotypes-for-co2-n2-separation
#6
Michael Fischer
Zeolites and structurally related materials (zeotypes) have received considerable attention as potential adsorbents for selective carbon dioxide adsorption. Within this group, zeotypes with aluminophosphate composition (AlPOs) could be an interesting alternative to the more frequently studied aluminosilicate zeolites. So far, however, only a few AlPOs have been characterised experimentally in terms of their CO2 adsorption properties. In this study, force-field based grand-canonical Monte Carlo (GCMC) simulations were used to evaluate the potential of AlPOs for CO2/N2 separation, a binary mixture that constitutes a suitable model system for the removal of carbon dioxide from flue gases...
August 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28810831/application-of-a-bayesian-non-linear-model-hybrid-scheme-to-sequence-data-for-genomic-prediction-and-qtl-mapping
#7
Tingting Wang, Yi-Ping Phoebe Chen, Iona M MacLeod, Jennie E Pryce, Michael E Goddard, Ben J Hayes
BACKGROUND: Using whole genome sequence data might improve genomic prediction accuracy, when compared with high-density SNP arrays, and could lead to identification of casual mutations affecting complex traits. For some traits, the most accurate genomic predictions are achieved with non-linear Bayesian methods. However, as the number of variants and the size of the reference population increase, the computational time required to implement these Bayesian methods (typically with Monte Carlo Markov Chain sampling) becomes unfeasibly long...
August 15, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28809947/high-density-genetic-linkage-map-construction-by-f2-populations-and-qtl-analysis-of-early-maturity-traits-in-upland-cotton-gossypium-hirsutum-l
#8
Libei Li, Shuqi Zhao, Junji Su, Shuli Fan, Chaoyou Pang, Hengling Wei, Hantao Wang, Lijiao Gu, Chi Zhang, Guoyuan Liu, Dingwei Yu, Qibao Liu, Xianlong Zhang, Shuxun Yu
Due to China's rapidly increasing population, the total arable land area has dramatically decreased; as a consequence, the competition for farming land allocated for grain and cotton production has become fierce. Therefore, to overcome the existing contradiction between cotton grain and fiber production and the limited farming land, development of early-maturing cultivars is necessary. In this research, a high-density linkage map of upland cotton was constructed using genotyping by sequencing (GBS) to discover single nucleotide polymorphism (SNP) markers associated with early maturity in 170 F2 individuals derived from a cross between LU28 and ZHONG213...
2017: PloS One
https://www.readbyqxmd.com/read/28808612/para-i-famagu-on-ta-fruit-and-vegetable-intake-food-store-environment-and-childhood-overweight-obesity-in-the-children-s-healthy-living-program-on-guam
#9
Lenora Matanane, Marie Kainoa Fialkowski, Joshua Silva, Fenfang Li, Claudio Nigg, Rachael T Leon Guerrero, Rachel Novotny
This cross-sectional study examined the: (1) association between food store environment (FSE), fruit and vegetable (FV) availability and access, and prevalence of early childhood overweight/obesity (COWOB); and (2) influence of young child actual FV intake on the relationship between the FSE and early COWOB prevalence. Anthropometric and socio-demographic data of children (2 to 8 years; N=466) in baseline communities on Guam participating in the Children's Healthy Living (CHL) Program community trial were included...
August 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28805257/three-representative-inter-and-intra-subspecific-crosses-reveal-the-genetic-architecture-of-reproductive-isolation-in-rice
#10
Guangwei Li, Xiaoting Li, Yuan Wang, Jiaming Mi, Feng Xing, Dahan Zhang, Qiyan Dong, Xianghua Li, Jinghua Xiao, Qifa Zhang, Yidan Ouyang
Systematic characterization of genetic and molecular mechanisms in formation of hybrid sterility is of fundamental importance in understanding reproductive isolation and speciation. Using ultra-high-density genetic maps, 43 single-locus QTLs and 223 digenic interactions for embryo-sac, pollen, and spikelet fertility are depicted from three crosses between representative varieties of japonica and two varietal groups of indica, which provide an extensive archive for investigating the genetic basis of reproductive isolation in rice...
August 14, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28801212/intraoperative-validation-of-quantitative-t2-mapping-in-patients-with-articular-cartilage-lesions-of-the-knee
#11
S Soellner, A Goldmann, D Muelheims, G H Welsch, M Pachowsky
OBJECTIVE: The aim of this study was to compare T2 relaxation times of knee cartilage with intraoperative results for the assessment of early osteoarthritis (OA) and to define T2 values for the differentiation between healthy and degenerated cartilage. DESIGN: Twenty-one patients with cartilage lesions or moderate OA were examined using 3T magnetic resonance imaging (MRI). In this prospective study, a total of 882 regions of interest (ROIs) were examined by a sagittal, multi-echo, spin-echo T2 sequence and a morphological high-resolution three-dimensional, fat-saturated proton-density space sequence...
August 8, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28799375/comparison-of-liquid-state-anomalies-in-stillinger-weber-models-of-water-silicon-and-germanium
#12
Debdas Dhabal, Charusita Chakravarty, Valeria Molinero, Hemant K Kashyap
We use molecular dynamics simulations to compare and contrast the liquid-state anomalies in the Stillinger-Weber models of monatomic water (mW), silicon (Si), and germanium (Ge) over a fairly wide range of temperatures and densities. The relationships between structure, entropy, and mobility, as well as the extent of the regions of anomalous behavior, are discussed as a function of the degree of tetrahedrality. We map out the cascade of density, structural, pair entropy, excess entropy, viscosity, and diffusivity anomalies for these three liquids...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28797676/electrogram-signature-of-specific-activation-patterns-analysis-of-atrial-tachycardias-at-high-density-endocardial-mapping
#13
Antonio Frontera, Masateru Takigawa, Ruairidh Martin, Nathaniel Thompson, Ghassen Cheniti, Gregoire Massouille, Josselin Duchateau, JeanYves Wielandts, Elvis Teijera, Takeshi Kitamura, Michael Wolf, Nora Al-Jefairi, Konstantinos Vlachos, Seigo Yamashita, Sana Amraoui, Arnaud Denis, Meleze Hocini, Hubert Cochet, Frederic Sacher, Pierre Jaïs, Michel Haïssaguerre, Nicolas Derval
BACKGROUND: The significance of fractionated electrograms (EGMs) is object of debate with multiple mechanisms described. OBJECTIVE: Using Rhythmia™, a high-density mapping system, we sought to investigate the relationship between specific electrophysiological phenomena and EGM characteristics at those sites. METHODS: 25 consecutive patients underwent High Density (HD) atrial mapping during Atrial Tachycardias (ATs). Bipolar EGMs were recorded with a 64-electrode basket catheter...
August 7, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28797038/plant-diversity-and-structure-describe-the-presence-of-a-new-threatened-australian-marsupial-within-its-highly-restricted-post-fire-habitat
#14
Eugene D Mason, Jennifer Firn, Harry B Hines, Andrew M Baker
Management of critical habitat for threatened species with small ranges requires location-specific, fine-scale survey data. The silver-headed antechinus (Antechinus argentus) is known from only two isolated, fire-prone locations. At least one of these populations, at Kroombit Tops National Park in central-eastern Queensland, Australia, possesses a very small range. Here, we present detailed vegetation species diversity and structure data from three sites comprising the known habitat of A. argentus at Kroombit Tops and relate it to capture data obtained over two years...
2017: PloS One
https://www.readbyqxmd.com/read/28794480/chromosome-structural-variation-of-two-cultivated-tetraploid-cottons-and-their-ancestral-diploid-species-based-on-a-new-high-density-genetic-map
#15
Wen-Wen Wang, Zhao-Yun Tan, Ya-Qiong Xu, Ai-Ai Zhu, Yan Li, Jiang Yao, Rui Tian, Xiao-Mei Fang, Xue-Ying Liu, You-Ming Tian, Zhong-Hua Teng, Jian Zhang, Da-Jun Liu, De-Xin Liu, Hai-Hong Shang, Fang Liu, Zheng-Sheng Zhang
A high-resolution genetic map is a useful tool for assaying genomic structural variation and clarifying the evolution of polyploid cotton. A total of 36956 SSRs, including 11289 released in previous studies and 25567 which were newly developed based on the genome sequences of G. arboreum and G. raimondii, were utilized to construct a new genetic map. The new high-density genetic map includes 6009 loci and spanned 3863.97 cM with an average distance of 0.64 cM between consecutive markers. Four inversions (one between Chr08 and Chr24, one between Chr09 and Chr23 and two between Chr10 and Chr20) were identified by homology analysis...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28792356/kinetic-evaluation-and-test-retest-reproducibility-of-11-c-ucb-j-a-novel-radioligand-for-positron-emission-tomography-imaging-of-synaptic-vesicle-glycoprotein-2a-in-humans
#16
Sjoerd J Finnema, Nabeel B Nabulsi, Joël Mercier, Shu-Fei Lin, Ming-Kai Chen, David Matuskey, Jean-Dominique Gallezot, Shannan Henry, Jonas Hannestad, Yiyun Huang, Richard E Carson
Synaptic vesicle glycoprotein 2A (SV2A) is ubiquitously present in presynaptic terminals. Here we report kinetic modeling and test-retest reproducibility assessment of the SV2A positron emission tomography (PET) radioligand [(11)C]UCB-J in humans. Five volunteers were examined twice on the HRRT after bolus injection of [(11)C]UCB-J. Arterial blood samples were collected for measurements of radiometabolites and free fraction. Regional time-activity curves were analyzed with 1-tissue (1T) and 2-tissue (2T) compartment models to estimate volumes of distribution ( VT)...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28791136/range-contractions-of-the-world-s-large-carnivores
#17
Christopher Wolf, William J Ripple
The majority of the world's terrestrial large carnivores have undergone substantial range contractions and many of these species are currently threatened with extinction. However, there has been little effort to fully quantify the extent of large carnivore range contractions, which hinders our ability to understand the roles and relative drivers of such trends. Here we present and analyse a newly constructed and comprehensive set of large carnivore range contraction maps. We reveal the extent to which ranges have contracted since historical times and identify regions and biomes where range contractions have been particularly large...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28777822/quantifying-gaze-and-mouse-interactions-on-spatial-visual-interfaces-with-a-new-movement-analytics-methodology
#18
Urška Demšar, Arzu Çöltekin
Eye movements provide insights into what people pay attention to, and therefore are commonly included in a variety of human-computer interaction studies. Eye movement recording devices (eye trackers) produce gaze trajectories, that is, sequences of gaze location on the screen. Despite recent technological developments that enabled more affordable hardware, gaze data are still costly and time consuming to collect, therefore some propose using mouse movements instead. These are easy to collect automatically and on a large scale...
2017: PloS One
https://www.readbyqxmd.com/read/28777720/delay-differential-analysis-of-seizures-in-multichannel-electrocorticography-data
#19
Claudia Lainscsek, Jonathan Weyhenmeyer, Sydney S Cash, Terrence J Sejnowski
High-density electrocorticogram (ECoG) electrodes are capable of recording neurophysiological data with high temporal resolution with wide spatial coverage. These recordings are a window to understanding how the human brain processes information and subsequently behaves in healthy and pathologic states. Here, we describe and implement delay differential analysis (DDA) for the characterization of ECoG data obtained from human patients with intractable epilepsy. DDA is a time-domain analysis framework based on embedding theory in nonlinear dynamics that reveals the nonlinear invariant properties of an unknown dynamical system...
August 4, 2017: Neural Computation
https://www.readbyqxmd.com/read/28776822/ripple-mapping-initial-multicenter-experience-of-an-intuitive-approach-to-overcoming-the-limitations-of-3d-activation-mapping
#20
Vishal Luther, Nuno Cortez-Dias, Luis Carpinteiro, João de Sousa, Richard Navaratnum Balasubramaniam, Sharad C Agarwal, David Farwell, Solomon Mark Sopher, Girish Babu, Richard Till, Nikki Jones, Stuart Tan, Anthony Chow, Martin Lowe, Jem Lane, Naveen Pappachan, Nick Wf Linton, Prapa Kanagaratnam
BACKGROUND: Ripple Mapping (RM) displays electrograms as moving bars over a 3D surface displaying bipolar voltage, and has shown in a single-center series to be effective for atrial tachycardia (AT) mapping without annotation of local activation time or window-of-interest assignment. We tested the reproducibility of these findings in operators naive to RM, using it for the first time in post ablation AT. METHODS: Maps were collected with multielectrode catheters and CARTO ConfiDENSE...
August 4, 2017: Journal of Cardiovascular Electrophysiology
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