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Mannitol aki cardiac surgery

Raquel Moreira, Tiago Jacinto, Paulo Neves, Luís Vouga, Cristina Baeta
INTRODUCTION: Acute kidney injury (AKI) in the postoperative period of cardiac surgery occurs in 1 to 30% of the patients, mainly caused by ischemia secondary to renal hypoperfusion. Cardiopulmonary bypass (CPB) has a deleterious effect on renal function, constituting an aggression to the patient's homeostasis. AIM: To evaluate the incidence of AKI in the postoperative period of cardiac surgery in patients without preoperative renal insufficiency who underwent cardiac surgery with CPB, and explore the association between incidence of AKI and predictors related to CPB...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Yasuhisa Okamoto, Tosihiro Nohmi, Koichiro Seki, Yuki Higa
Chronic renal failure (CRF) is related to cardiac diseases. Cardiac surgery is also related to postoperative acute kidney injury (AKI). It means heart and kidney have close relationship. We analyzed recent published data to understand how to manage CRF patients undergoing cardiovascular surgeries. We compared endovascular surgery and open procedure for aortic aneurysm, especially about contrast media-related renal damage, On or Off CABG or PCI for ischemic heart disease. We also discussed the relation between cardiopulmonary bypass and AKI and the risk factors causing AKI after CPB...
November 2013: Masui. the Japanese Journal of Anesthesiology
Gudrun Bragadottir, Bengt Redfors, Sven-Erik Ricksten
INTRODUCTION: Acute kidney injury (AKI), which is a major complication after cardiovascular surgery, is associated with significant morbidity and mortality. Diuretic agents are frequently used to improve urine output and to facilitate fluid management in these patients. Mannitol, an osmotic diuretic, is used in the perioperative setting in the belief that it exerts reno-protective properties. In a recent study on uncomplicated postcardiac-surgery patients with normal renal function, mannitol increased glomerular filtration rate (GFR), possibly by a deswelling effect on tubular cells...
August 17, 2012: Critical Care: the Official Journal of the Critical Care Forum
Rossana Romani, Marja Silvasti-Lundell, Aki Laakso, Hanna Tuominen, Juha Hernesniemi, Tomi Niemi
BACKGROUND: Surgery of skull base meningiomas by the lateral supraorbital (LSO) approach requires relaxed brain. Therefore, we assessed combined effects of the elements of neuroanesthesia on neurosurgical conditions during craniotomy. METHODS: The anesthesiological and surgical charts of 66 olfactory groove, 73 anterior clinoidal, and 52 tuberculum sellae meningioma patients operated on by the senior author (J.H.) at the Department of Neurosurgery of Helsinki University Central Hospital, Helsinki, Finland, between September 1997 and August 2010, were retrospectively analyzed...
2011: Surgical Neurology International
Ling Guanghui Ling, Ni Zeng, Jiajun Liu, Youming Peng, Shaobin Duan, Yuncheng Xia, Hong Liu, Yinghong Liu, Jun Li, Ying Li, Lin Sun, Fuyou Liu
OBJECTIVE: To determine the incidence and risk factors associated with acute kidney injury (AKI) in patients after cardiac surgery with extracorporeal circulation. METHODS: A retrospective case control study was done in patients who underwent cardiac surgery from 2003 to 2007 in Second Xiangya Hospital, with 340 patients in an AKI group and the other 4 760 patients without AKI as a control group. All variables were analyzed by univariate analysis, Mann-Whitney U test and logistic regression...
September 2009: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
R Lombardi
Acute kidney injury (AKI) is a frequent and severe disorder that is observed in a variety of clinical settings. Early recognition of this syndrome is of critical importance in order to prevent progression to more severe forms, which are associated with a higher risk of complications and death. Efforts to prevent AKI have been made through a variety of interventions and drugs. However, no benefit has been demonstrated to date except for volume expansion and avoidance of nephrotoxic drugs. Diuretics have been extensively studied because of their main pharmacokinetic actions: reduction of renal vascular resistance and inhibition of active transport in the thick ascending limb, which reduces the energy requirement and eventually protects cells under ischemic conditions...
September 2008: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
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