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https://www.readbyqxmd.com/read/29924785/-embryology-anatomy-and-rare-pathologies-of-the-popliteal-artery-peculiarities-of-surgical-treatment
#1
M R Kuznetsov, I V Reshetov, L A Magnitskiĭ, Vasiliev V, I P Marchenko, A D Matveev, A A Lugovoĭ, M S Tverskaia
Knowledge of anatomical variations of the division of the popliteal artery and specific lesions of the arterial segment involved is necessary for the surgeon, traumatologist-orthopaedist, vascular surgeon. The article contains a review of recent literature data on the prevalence of different variants of branching patterns of the arteries of the crus, also providing a detailed discussion of embryological development of the arterial system of the lower extremities, in many ways explaining the appearance of rare pathologies of the popliteal artery, such as for example popliteal artery entrapment syndrome...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29922650/ultrasound-and-infrared-based-imaging-modalities-for-diagnosis-and-management-of-cutaneous-diseases
#2
REVIEW
Sheliza Halani, F Stuart Foster, Maksym Breslavets, Neil H Shear
Non-invasive bedside imaging tools are becoming more prevalent for assessing cutaneous lesions. Ultrasound used at specific frequencies allows us to assess margins of lesions to minimize the extent of the biopsy that is performed and improve cosmetic outcomes. Vascularity, seen on Doppler ultrasound and contrast-enhanced ultrasound, and stiffness, assessed on tissue elastography, can help differentiate between benign and malignant lesions for clinicians to be more judicious in deciding whether to biopsy. Moreover, research has shown the efficacy in using ultrasound in monitoring flares of hidradenitis suppurativa, a disease affecting apocrine gland-rich areas of the body, for which the current gold standard involves examining and scoring inflammatory lesions with the naked eye...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29917073/detection-of-distant-interval-metastases-after-neoadjuvant-therapy-for-esophageal-cancer-with-18f-fdg-pet-ct-a-systematic-review-and-meta-analysis
#3
T E Kroese, L Goense, R van Hillegersberg, B de Keizer, S Mook, J P Ruurda, P S N van Rossum
Restaging after neoadjuvant therapy aims to reduce the number of patients undergoing esophagectomy in case of distant (interval) metastases. The aim of this study is to systematically review and meta-analyze the diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) and 18F-FDG PET/CT for the detection of distant interval metastases after neoadjuvant therapy in patients with esophageal cancer. PubMed/MEDLINE, Embase, and the Cochrane library were systematically searched...
June 16, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29910721/better-diffusion-segmentation-in-acute-ischemic-stroke-through-automatic-tree-learning-anomaly-segmentation
#4
Jens K Boldsen, Thorbjørn S Engedal, Salvador Pedraza, Tae-Hee Cho, Götz Thomalla, Norbert Nighoghossian, Jean-Claude Baron, Jens Fiehler, Leif Østergaard, Kim Mouridsen
Stroke is the second most common cause of death worldwide, responsible for 6.24 million deaths in 2015 (about 11% of all deaths). Three out of four stroke survivors suffer long term disability, as many cannot return to their prior employment or live independently. Eighty-seven percent of strokes are ischemic. As an increasing volume of ischemic brain tissue proceeds to permanent infarction in the hours following the onset, immediate treatment is pivotal to increase the likelihood of good clinical outcome for the patient...
2018: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/29908523/radiographic-study-of-haematogenous-septic-arthritis-in-dairy-calves
#5
Caroline Constant, Isabelle Masseau, Marie Babkine, Sylvain Nichols, David Francoz, Gilles Fecteau, Emma Marchionatti, Helene Larde, Andre Desrochers
OBJECTIVES:  (1) To develop an evaluation grid to provide a systematic interpretation of calves' articular radiographs, (2) to describe radiographic lesions of septic arthritis in dairy calves less than 6 months of age, (3) to investigate potential associations between demographic data or synovial bacteriological culture results and radiographic lesions (4) to determine whether an association is present between radiographic lesions, their severity and the long-term outcome. METHODS:  Medical records of 54 calves less than 180 days old treated for septic arthritis between 2009 and 2014 with radiographic images performed in the first 2 days after admission were reviewed...
June 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29887240/intratumor-heterogeneity-in-prostate-cancer
#6
REVIEW
Shalini S Yadav, Jennifer A Stockert, Victoria Hackert, Kamlesh K Yadav, Ashutosh K Tewari
Prostate cancer (PCa) has long been thought of as a disease with a heterogeneous phenotype. It can manifest in men as benign growths that can be safely watched or as more aggressive malignancies that can prove fatal. Recent investigations at the genomic, histopathological and molecular levels have identified tumor heterogeneity, the phenomenon of individual tumor cells presenting distinct genomic and phenotypic characteristics, as one of the most confounding and complex factors underlying PCa diagnosis, prognosis, and treatment...
June 7, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29886437/prevalence-of-knee-osteoarthritis-features-on-magnetic-resonance-imaging-in-asymptomatic-uninjured-adults-a-systematic-review-and-meta-analysis
#7
REVIEW
Adam G Culvenor, Britt Elin Øiestad, Harvi F Hart, Joshua J Stefanik, Ali Guermazi, Kay M Crossley
BACKGROUND: Knee MRI is increasingly used to inform clinical management. Features associated with osteoarthritis are often present in asymptomatic uninjured knees; however, the estimated prevalence varies substantially between studies. We performed a systematic review with meta-analysis to provide summary estimates of the prevalence of MRI features of osteoarthritis in asymptomatic uninjured knees. METHODS: We searched six electronic databases for studies reporting MRI osteoarthritis feature prevalence (ie, cartilage defects, meniscal tears, bone marrow lesions and osteophytes) in asymptomatic uninjured knees...
June 9, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29883968/relationship-of-in-vivo-mr-parameters-to-histopathological-and-molecular-characteristics-of-newly-diagnosed-nonenhancing-lower-grade-gliomas
#8
Tracy L Luks, Tracy Richmond McKnight, Llewellyn E Jalbert, Aurelia Williams, Evan Neill, Khadjia A Lobo, Anders I Persson, Arie Perry, Joanna J Phillips, Annette M Molinaro, Susan M Chang, Sarah J Nelson
The goal of this research was to elucidate the relationship between WHO 2016 molecular classifications of newly diagnosed, nonenhancing lower grade gliomas (LrGG), tissue sample histopathology, and magnetic resonance (MR) parameters derived from diffusion, perfusion, and 1 H spectroscopic imaging from the tissue sample locations and the entire tumor. A total of 135 patients were scanned prior to initial surgery, with tumor cellularity scores obtained from 88 image-guided tissue samples. MR parameters were obtained from corresponding sample locations, and histograms of normalized MR parameters within the T2 fluid-attenuated inversion recovery lesion were analyzed in order to evaluate differences between subgroups...
June 5, 2018: Translational Oncology
https://www.readbyqxmd.com/read/29881637/use-of-trachea-bronchial-swab-qpcr-testing-to-confirm-mycoplasma-hyopneumoniae-seropositivity-in-an-spf-breeding-herd
#9
Frédéric Vangroenweghe, Eveline Willems, Jiří Malášek, Olivier Thas, Dominiek Maes
Background: A dedicated program to monitor for freedom of several economically important diseases is present within most of the breeding companies that currently deliver high health breeding animals to their customers. Serology is therefore the preferential approach in order to screen for most of these diseases, including Mycoplasma hyopneumoniae ( M. hyopneumoniae ). However, in case of positive serology, further decisions on farm health status and the related consequences should be based on additional confirmation tests...
2018: Porcine Health Management
https://www.readbyqxmd.com/read/29872644/response-to-her2-inhibition-in-a-patient-with-brain-metastasis-with-egfr-tki-acquired-resistance-and-an-her2-amplification
#10
Arenda D Meedendorp, Arja Ter Elst, Nils A 't Hart, Harry J M Groen, Ed Schuuring, Anthonie J van der Wekken
A 62-year-old man was referred to our university hospital for treatment of advanced adenocarcinoma of the lung after disease progression on two lines of EGFR TKI and one line of chemotherapy. Fluorescent in situ hybridization analysis upon progression showed an HER2 amplification. At our weekly Molecular Tumor Board (MTB), a decision was made to treat this patient with afatinib, which resulted in a partial response. However, progression was observed with a facial nerve paresis due to a metastasis in the skull...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29860765/-the-role-of-preoperative-18-f-fdg-pet-ct-in-lymphatic-metastasis-diagnosis-of-cutaneous-malignant-melanoma-on-extremities-and-trunk
#11
X X Zhang, Y Fang, L B Xu, S F Xu, Z G Zhao, C Sun, P Q Ma, T Liu, S J Yu, W J Zhang
Objective: To evaluate the clinical value of preoperative (18)F-Fludeoxyglucose ((18)F-FDG PET-CT) in lymphatic metastasis diagnosis of cutaneous melanoma on extremities and trunk. Methods: 112 patients with cutaneous melanoma pathologically of extremities and trunk from January 2006 to December 2016, who received (18)F-FDG PET-CT examination preoperatively, were retrospectively reviewed. The correlations between the maximal diameters of lymph nodes, the maximal standard uptake value (SUV) and the diagnostic impression grades of PET-CT examination, and the final pathological diagnosis were analyzed...
May 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29851416/renal-mass-biopsy-an-oncological-conundrum
#12
Roshan M Patel, Egor Parkhomenko, Kamaljot S Kaler, Zhamshid Okhunov, Ralph V Clayman, Jaime Landman
PURPOSE OF REVIEW: We evaluate the reasons that the majority of urologists infrequently biopsy a T1a small renal mass (SRM). RECENT FINDINGS: The majority of urologists report that a renal mass biopsy will not change their management in patients with a SRM given concerns of safety and efficacy of the biopsy. However, when comparing the safety and efficacy of SRM biopsy with neoplasms in all other major organ systems (all of which require biopsy prior to treatment), renal mass biopsy results are favorable...
July 2018: Current Opinion in Urology
https://www.readbyqxmd.com/read/29846414/malignancy-rates-for-bethesda-iii-subcategories-in-thyroid-fine-needle-aspiration-biopsy-fnab
#13
Leticia Mosca, Luiz Fernando Ferraz da Silva, Paulo Campos Carneiro, Danielle Azevedo Chacon, Vergilius Jose Furtado de Araujo-Neto, Vergilius Jose Furtado de Araujo-Filho, Claudio Roberto Cernea
OBJECTIVES: Most thyroid diseases are nodular and have been investigated using ultrasound-guided fine needle aspiration biopsy (FNAB), the reports of which are standardized by the Bethesda System. Bethesda category III represents a heterogeneous group in terms of lesion characteristics and the malignancy rates reported in the literature. The objective of the present study was to evaluate the differences in the malignancy rates among Bethesda III subcategories. METHODS: Data from 1,479 patients who had thyroid surgery were reviewed...
2018: Clinics
https://www.readbyqxmd.com/read/29804736/a-systematic-review-and-meta-analysis-of-revascularization-outcomes-of-infrainguinal-chronic-limb-threatening-ischemia
#14
Jehad Almasri, Jayanth Adusumalli, Noor Asi, Sumaya Lakis, Mouaz Alsawas, Larry J Prokop, Andrew Bradbury, Philippe Kolh, Michael S Conte, M Hassan Murad
BACKGROUND: The optimal strategy for revascularization in infrainguinal chronic limb-threatening ischemia (CLTI) remains debatable. Comparative trials are scarce, and daily decisions are often made using anecdotal or low-quality evidence. METHOD: We searched multiple databases through May 7, 2017, for prospective studies with at least 1-year follow-up that evaluated patient-relevant outcomes of infrainguinal revascularization procedures in adults with CLTI. Independent pairs of reviewers selected articles and extracted data...
May 24, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29797507/the-ghent-global-iad-monitoring-tool-globiad-m-to-monitor-the-healing-of-incontinence-associated-dermatitis-iad-design-and-reliability-study
#15
Karen Van den Bussche, Sofie Verhaeghe, Ann Van Hecke, Dimitri Beeckman
The aim of this study was to design and evaluate the reliability of the Ghent Global incontinence-associated dermatitis (IAD) Monitoring Tool (GLOBIAD-M). The tool was designed based on the internationally validated Ghent Global IAD Categorisation Tool (GLOBIAD). After designing and validation by experts, one trained researcher carried out 36 observations of 9 patients affected with IAD. Photographs of the IAD lesions were independently assessed by a second trained researcher. Measures for inter-rater agreement (p o ) and reliability [Cohen's Kappa (ĸ) and intra-class correlation coefficients (ICC)] were analysed...
May 24, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29796909/clinical-impact-of-kras-and-gnas-analysis-added-to-cea-and-cytology-in-pancreatic-cystic-fluid-obtained-by-eus-fna
#16
Sandra Faias, Marlene Duarte, Cristina Albuquerque, João Pereira da Silva, Ricardo Fonseca, Ruben Roque, Antonio Dias Pereira, Paula Chaves, Marília Cravo
BACKGROUND: Pancreatic cysts are common incidental findings with malignant potential, raising diagnostic and treatment dilemmas. AIMS: To determine the added value of KRAS and GNAS mutation analysis on cyst classification and decision making. METHODS: We analyzed 52 frozen samples of pancreatic cystic fluid obtained by EUS-FNA between 2008 and 2014. In addition to cytology and CEA, mutations of GNAS (exons 8 and 9) and KRAS (exons 2 and 3) genes were analyzed using Sanger sequencing...
May 24, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29796401/learning-from-failure-in-cartilage-repair-surgery-an-analysis-of-the-mode-of-failure-of-primary-procedures-in-consecutive-cases-at-a-tertiary-referral-center
#17
Aaron J Krych, Mario Hevesi, Vishal S Desai, Christopher L Camp, Michael J Stuart, Daniel B F Saris
Background: As the number of cartilage restoration procedures is increasing, so is the number of revision procedures. However, there remains limited information on the reasons for failure of primary cartilage restoration procedures. Purpose: To determine the common modes of failure in primary cartilage restoration procedures to improve surgical decision making and patient outcomes. Study Design: Case series; Level of evidence, 4. Methods: Patients who presented for revision after failed cartilage repair surgery were evaluated for factors contributing to failure of the primary procedure...
May 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29795133/specializations-for-reward-guided-decision-making-in-the-primate-ventral-prefrontal-cortex
#18
REVIEW
Elisabeth A Murray, Peter H Rudebeck
The estimated values of choices, and therefore decision-making based on those values, are influenced by both the chance that the chosen items or goods can be obtained (availability) and their current worth (desirability) as well as by the ability to link the estimated values to choices (a process sometimes called credit assignment). In primates, the prefrontal cortex (PFC) has been thought to contribute to each of these processes; however, causal relationships between particular subdivisions of the PFC and specific functions have been difficult to establish...
May 23, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29794478/carious-lesion-diagnosis-methods-problems-thresholds
#19
Klaus W Neuhaus, Adrian Lussi
The difference between carious lesion diagnosis and carious lesion detection is discussed here. Concerning carious lesions, 3 diagnostic requirements should be fulfilled: to detect lesions, to assess surface integrity, and to assess lesion activity to support clinical decision making. The first and most important diagnostic method is meticulous visual-tactile inspection. This is the only method that potentially contributes to all 3 diagnostic requirements. All other methods that are presented in this chapter, i...
May 24, 2018: Monographs in Oral Science
https://www.readbyqxmd.com/read/29791295/ultrasonographic-detection-of-ingested-fishing-lines-in-loggerheads-caretta-caretta
#20
Delia Franchini, Carmela Valastro, Stefano Ciccarelli, Francesco Caprio, Diana Lenoci, Antonio Di Bello
Loggerhead sea turtles ( Caretta caretta) are among the most frequent victims of bycatch in drifting longlines, and the ingestion of fish hooks and fishing lines is one of the most frequent causes of death of sea turtles. The aim of this study was to evaluate whether coelomic ultrasound (US) can be decisive, not only for diagnosis but also to optimize surgical planning based on preoperative evaluation of the bowel conditions and, in addition, to see if there are characteristic sonographic findings in sea turtles associated with the ingestion of fishing lines...
May 23, 2018: Journal of Wildlife Diseases
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