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https://www.readbyqxmd.com/read/29040454/to-fly-as-a-pilot-after-cardiac-surgery
#1
Thomas Syburra, Ed Nicol, Stuart Mitchell, Denis Bron, Ulrich Rosendahl, John Pepper
Aircrew are responsible for safe and reliable aircraft operations. Cardiovascular disease accounts for 50% of all pilot licences declined or withdrawn for medical reasons in Western Europe and is the most common cases of sudden incapacitation in flight. Aircrew retirement age is increasing (up to age 65) in a growing number of airlines and the burden of subclinical, but potentially significant, coronary atherosclerosis is unknown in qualified pilots above age 40. Safety considerations are paramount in aviation medicine, and the most dreaded cardiovascular complications are thromboembolic events and rhythm disturbances due to their potential for sudden incapacitation...
October 13, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29040244/a-prospective-study-of-the-causes-of-bruises-in-premobile-infants
#2
Kenneth W Feldman, Tricia M Tayama, Leslie E Strickler, Lee A Johnson, Gauri Kolhatkar, Catherine A DeRidder, Dana C Matthews, Robert Sidbury, James A Taylor
OBJECTIVE: This study had 2 objectives. First, to determine the behavior of physicians evaluating premobile infants with bruises. Second, and most importantly, to learn whether infants with unexplained bruising who had been initially evaluated by primary care and emergency department (ED) physicians are as likely to have their bruises attributed to child abuse as those children evaluated by child abuse physicians. METHODS: Primary care, ED, and child abuse pediatricians (CAPs) in King County, Washington, San Mateo, Calif, Albuquerque, NM, La Crosse, Wis, and Torrance, Calif prospectively identified and studied infants younger than 6 months with less than 6 bruises, which were judged by the evaluating clinician to be explained or unexplained after their initial clinical examination...
October 16, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29040071/prevalence-and-direct-costs-of-emergency-department-visits-and-hospitalizations-for-selected-diseases-that-can-be-transmitted-by-water-united-states
#3
E A Adam, S A Collier, K E Fullerton, J W Gargano, M J Beach
National emergency department (ED) visit prevalence and costs for selected diseases that can be transmitted by water were estimated using large healthcare databases (acute otitis externa, campylobacteriosis, cryptosporidiosis, Escherichia coli infection, free-living ameba infection, giardiasis, hepatitis A virus (HAV) infection, Legionnaires' disease, nontuberculous mycobacterial (NTM) infection, Pseudomonas-related pneumonia or septicemia, salmonellosis, shigellosis, and vibriosis or cholera). An estimated 477,000 annual ED visits (95% CI: 459,000-494,000) were documented, with 21% (n = 101,000, 95% CI: 97,000-105,000) resulting in immediate hospital admission...
October 2017: Journal of Water and Health
https://www.readbyqxmd.com/read/29036574/differential-expression-of-hypertensive-phenotypes-in-bxd-mouse-strains-in-response-to-angiotensin-ii
#4
Wenyuan Zhao, Tieqiang Zhao, Yuanjian Chen, Syamal K Bhattacharya, Lu Lu, Yao Sun
BACKGROUND: Besides environmental risk factors, genetic factors play a crucial role in the pathogenesis of primary hypertension. The current study is to unravel whether hypertensive phenotypes vary in mice with different genetic background. METHODS: Hypertension was induced in C57BL/6J (B6), DBA/2J (D2), and 25 BXD strains by administrating angiotensin (Ang)II (2.5 mg/kg/day infused by osmotic minipump) for 4 weeks. Systolic blood pressure was monitored before (baseline) and after 4 weeks of AngII treatment by tail cuff...
September 23, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/29036573/complexviewer-visualization-of-curated-macromolecular-complexes
#5
Colin W Combe, Marine Dumousseau Sivade, Henning Hermjakob, Joshua Heimbach, Birgit H M Meldal, Gos Micklem, Sandra Orchard, Juri Rappsilber
Summary: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. Availability and implementation: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www...
August 3, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036031/value-of-the-delta-neutrophil-index-for-predicting-28-day-mortality-in-patients-with-acute-pulmonary-embolism-in-the-emergency-department
#6
Taeyoung Kong, Yoo Seok Park, Hye Sun Lee, Sinae Kim, Jong Wook Lee, Gina Yu, Claire Eun, Je Sung You, Hyun Soo Chung, Incheol Park, Sung Phil Chung
PURPOSE: Acute pulmonary embolism (PE), frequently seen in the emergency department (ED), is a leading cause of cardiovascular morbidity and mortality. The delta neutrophil index (DNI) reflects the fraction of circulating immature granulocytes as a component of the systemic inflammatory response syndrome criteria. The pathogenesis of acute PE is significantly associated with inflammation. The aim of the study was to investigate the clinical usefulness of the DNI as a marker of severity in patients with acute PE admitted to the ED...
October 14, 2017: Shock
https://www.readbyqxmd.com/read/29036004/the-utility-of-clinical-ultrasonography-in-identifying-distal-forearm-fractures-in-the-pediatric-emergency-department
#7
Iratxe Galletebeitia Laka, Frederic Samson, Inigo Gorostiza, Andrés Gonzalez, Carlos Gonzalez
OBJECTIVE: The aim of this study is to evaluate the utility of Point-Of-Care Ultrasound (POCUS) for diagnosing distal forearm fractures in pediatric emergency departments (ED). PATIENTS AND METHODS: A prospective observational study was carried out in children aged younger than 15 years attended in an ED with an indication of radiography because of a suspected distal forearm fracture. The POCUS was performed considering cortical irregularity or disruption compatible with fracture...
October 13, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29035611/are-people-who-inject-drugs-frequent-users-of-emergency-department-services-a-cohort-study-2008-2013
#8
Dhanya Nambiar, Tim Spelman, Mark Stoové, Paul Dietze
BACKGROUND: Although people who inject drugs (PWID) have been described as frequent users of emergency services, the majority of research is cross-sectional and involves records from a single emergency department (ED). OBJECTIVES: We describe characteristics of state-wide ED presentations in a cohort of PWID, and compare presentation rates to the general population. We also examine characteristics associated with frequent ED use. METHODS: We used data from a retrospective linkage of public ED presentations from a cohort of 678 PWID between January 2008 and June 2013...
October 16, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29035152/empirically-derived-classes-of-eating-pathology-in-male-and-female-college-students
#9
Brittany L Stevenson, Mun Yee Kwan, Robert D Dvorak, Kathryn H Gordon
BACKGROUND: The empirical structure of eating disorder (ED) pathology has often been studied in female, clinical samples, leaving questions about the structure of ED pathology in males and nonclinical samples. METHOD: A latent class analysis was performed on data combined from two different studies (N = 1,751) using the behavioral items in the Eating Disorder Examination Questionnaire (EDE-Q; binge eating, self-induced vomiting, laxative use, and excessive exercise), with the addition of an item representing restraint...
October 16, 2017: Eating Disorders
https://www.readbyqxmd.com/read/29035034/ultrasmall-mno-nanoparticles-supported-on-nitrogen-doped-carbon-nanotubes-as-efficient-anode-materials-for-sodium-ion-batteries
#10
Yanzhen He, Ping Xu, Bin Zhang, Yunchen Du, Song Bo, Xijiang Han, Huisheng Peng
Sodium ion batteries (SIBs) have attracted increasing attentions as promising alternatives to lithium ion batteries (LIBs). Herein, we design and synthesize ultrasmall MnO nanoparticles (~4 nm) supported on nitrogen-doped carbon nanotubes (NDCT@MnO) as promising anode materials of SIBs. It is revealed that the carbonization temperature can greatly influence the structural features and thus the Na-storage behavior of the NDCT@MnO nanocomposites. The synergetic interaction between MnO and NDCT in the NDCT@MnO nanocomposites provides high rate capability and long-term cycling life due to high surface area, electrical conductivity, enhanced diffusion rate of Na+ ions, and prevent-ed agglomeration and high stability of MnO nanoparticles...
October 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29033616/nationwide-trends-of-clinical-characteristics-and-economic-burden-of-emergency-department-visits-due-to-acute-ischemic-stroke
#11
Mark Stuntz, Katsiaryna Busko, Shumaila Irshad, Taylor Paige, Veranika Razhkova, Tim Coan
We aimed to provide estimates of the volume and associated charges of acute ischemic stroke (AIS) visits in the US, as well as to assess predictors of patient disposition following an emergency department (ED) visit for AIS. Our study was conducted using the 2010-2013 data from the Nationwide Emergency Department Sample. We identified adult visits with AIS as the primary diagnosis. A generalized linear model was used to calculate mean charges per visit after adjusting for covariates. Multinomial logistic regression was used to assess predictors of patient disposition following an ED visit for AIS...
2017: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/29033297/no-easy-way-out-a-case-of-physician-assisted-dying-in-the-emergency-department
#12
David H Wang
Currently, 1 out of 6 Americans lives within a jurisdiction in which physician-assisted dying is legally authorized. In most cases, patients ingest lethal physician-assisted dying medications at home without involvement of emergency medical services (EMS) or the emergency department (ED). However, occasionally the dying process is interrupted as a result of incomplete ingestion or vomiting of medications, confusion about timing of dying trajectory, familial emotional distress, and other variables. A case is presented here of a patient who arrived by ambulance to an urban ED after ingesting physician-assisted dying medication...
October 12, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29033296/a-comparison-of-headache-treatment-in-the-emergency-department-prochlorperazine-versus%C3%A2-ketamine
#13
Tony Zitek, Melanie Gates, Christopher Pitotti, Alexandria Bartlett, Jayme Patel, Aryan Rahbar, Wesley Forred, Joseph S Sontgerath, Jill M Clark
STUDY OBJECTIVE: Intravenous subdissociative-dose ketamine has been shown to be effective for pain management, but has not been specifically studied for headaches in the emergency department (ED). For this reason, we designed a study to compare standard treatment (prochlorperazine) with ketamine in patients with benign headaches in the ED. METHODS: This study was a multicenter, double-blind, randomized, controlled trial with a convenience sample of patients presenting to the ED with benign headaches...
October 13, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29033166/early-peripheral-endothelial-dysfunction-predicts-myocardial-infarct-extension-and-microvascular-obstruction-in-patients-with-st-elevation-myocardial-infarction
#14
Sérgio Bravo Baptista, Mariana Faustino, Luís Brizida, José Loureiro, João Augusto, João Abecasis, Célia Monteiro, Paulo Leal, Maura Nédio, Pedro Farto E Abreu, Victor Gil, Carlos Morais
INTRODUCTION AND OBJECTIVES: The role of endothelial dysfunction (ED) in patients with ST-elevation myocardial infarction (STEMI) is poorly understood. Peripheral arterial tonometry (PAT) allows non-invasive evaluation of ED, but has never been used for this purpose early after primary percutaneous coronary intervention (P-PCI). Our purpose was to analyze the relation between ED assessed by PAT and both the presence of microvascular obstruction (MVO) and infarct extension in STEMI patients...
October 12, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29033137/the-global-problem-of-early-deaths-in-acute-promyelocytic-leukemia-a-strategy-to-decrease-induction-mortality-in-the-most-curable-leukemia
#15
REVIEW
A P Jillella, V K Kota
Acute promyelocytic leukemia (APL) is a hyper-acute illness and presents with profound cytopenias in most patients and disseminated intravascular coagulation (DIC). Excellent treatment options are now available with drugs such as all-trans retinoic acid (ATRA), arsenic trioxide (ATO), anthracyclines and cytarabine. The outcome in APL has improved tremendously in the last 50years due to better understanding of the disease, development of effective targeted agents and improvement in supportive care. Carefully selected groups of patients treated in large multi-center trials on a protocol and in experienced centers have shown survival rates in excess of 85%...
September 18, 2017: Blood Reviews
https://www.readbyqxmd.com/read/29033028/the-implications-and-applications-of-learning-via-instructions
#16
EDITORIAL
Baptist Liefooghe, Senne Braem, Nachshon Meiran
Whereas psychology knows a long tradition of studies that focused on the role of practice and training in acquiring new skills or knowledge, systematic studies into learning via instructions remain relatively scarce. This is surprising given the tremendous influence instructions have on human behavior and cognition. In recent years, however, a (re)new(ed) interest into learning via instructions resulted in new paradigms and findings that can inspire future research in this understudied domain. We offer a brief overview of the articles in this special issue, which present some of the latest empirical developments dedicated to unraveling the implications and applications of learning via instructions...
October 12, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/29032870/insurance-status-and-access-to-urgent-primary-care-follow-up-after-an-emergency-department%C3%A2-visit-in-2016
#17
Shih-Chuan Chou, Yanhong Deng, Jerry Smart, Vivek Parwani, Steven L Bernstein, Arjun K Venkatesh
STUDY OBJECTIVE: We examine the availability of follow-up appointments for emergency department (ED) patients without established primary care by insurance and clinical condition. METHODS: We used "secret shopper" methodology, employing 2 black men to telephone all 53 primary care practices in greater New Haven, posing as new patients discharged from the ED and requesting follow-up appointments. Each practice received 6 scripted calls from each caller during an 8-month period, reflecting all possible scenarios based on 3 insurance types (Medicaid, state exchange, and commercial) and 2 conditions (hypertension and back pain)...
October 4, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29032791/deconstructing-the-4-h-rule-for-access-to-emergency-care-and-putting-patients-first
#18
Ian Scott, Clair Sullivan, Andrew Staib, Anthony Bell
Evidence suggests improved outcomes for patients requiring emergency admission to hospital are associated with improved emergency department (ED) efficiency and lower transit times. Factors preventing timely transfers of emergency patients to in-patient beds across the ED-in-patient interface are major causes for ED crowding, for which several remedial strategies are possible, including parallel processing of probable admissions, direct-to-ward admissions and single-point medical registrars for receiving and processing all referrals directed at specific speciality units...
October 16, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29032788/using-the-bergman-paris-question-to-screen-seniors-in-the-emergency-department
#19
Antoine Lague, Philippe Voyer, Marie-Christine Ouellet, Vale Rie Boucher, Marianne Giroux, Mathieu Pelletier, E Milie Gouin, Raoul Daoust, Simon Berthelot, Miche le Morin, Thien Tuong Minh Vu, Jacques Lee, Audrey-Anne Brousseau, Marie-Jose E Sirois, Marcel E Mond
OBJECTIVES: In the fast pace of the Emergency Department (ED), clinicians are in need of tailored screening tools to detect seniors who are at risk of adverse outcomes. We aimed to explore the usefulness of the Bergman-Paris Question (BPQ) to expose potential undetected geriatric syndromes in community-living seniors presenting to the ED. METHODS: This is a planned sub-study of the INDEED multicentre prospective cohort study, including independent or semi-independent seniors (≥65 years old) admitted to hospital after an ED stay ≥8 hours and who were not delirious...
October 16, 2017: CJEM
https://www.readbyqxmd.com/read/29032703/the-use-of-telepsychiatry-to-provide-cost-efficient-care-during-pediatric-mental-health-emergencies
#20
John F Thomas, Douglas K Novins, Patrick W Hosokawa, Christina A Olson, Dru Hunter, Alison S Brent, Gerard Frunzi, Anne M Libby
OBJECTIVE: This study evaluated a videoconference-based psychiatric emergency consultation program (telepsychiatry) at geographically dispersed emergency department (ED) sites that are part of the network of care of an academic children's hospital system. The study compared program outcomes with those of usual care involving ambulance transport to the hospital for in-person psychiatric emergency consultation prior to disposition to inpatient care or discharge home. METHODS: This study compared process outcomes in a cross-sectional, pre-post design at five network-of-care sites before and after systemwide implementation of telepsychiatry consultation in 2015...
October 16, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
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