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https://www.readbyqxmd.com/read/29228529/efficacy-of-bronchial-washing-and-brushing-cytology-in-the-diagnosis-of-non-neoplastic-lung-diseases
#1
Rahil Giti, Massood Hosseinzadeh
Flexible fiberoptic bronchoscopy is often the initial technique for diagnosis of lung and bronchial tumors. Many studies have shown the high accuracy rate of bronchial washing and brushing cytology in the evaluation of neoplastic and non-neoplastic bronchopulmonary lesions. The aim of this study is to emphasize the value of the bronchial cytologic findings for diagnosis of non-neoplastic bronchopulmonary lesions. In a cross-sectional study, we retrieved all cases with bronchial washing and brushing cytology from 21 Mach 2014 to 21 December 2015...
October 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29220357/difference-of-the-progression-of-pulmonary-cysts-assessed-by-computed-tomography-among-copd-lymphangioleiomyomatosis-and-birt-hogg-dub%C3%A3-syndrome
#2
Kazunori Tobino, Toyohiro Hirai, Takeshi Johkoh, Kiminori Fujimoto, Atsushi Kawaguchi, Noriyuki Tomiyama, Kazuhisa Takahashi, Kuniaki Seyama
Many groups developed the methods to quantitatively analyze low attenuation area (LAA) on chest CT in patients with cystic lung diseases. Especially in COPD, it was reported that the cumulative size distribution of LAA clusters follows a power law characterized by the exponent D, which reflect the fractal dimension of terminal airspace geometry. We hypoyhesized that the quantitative charateristics of LAA clusters including fractal property might indicate the different features of the progression of cysts in cystic lung diseases...
2017: PloS One
https://www.readbyqxmd.com/read/29216800/vascular-ehlers-danlos-syndrome-with-a-novel-missense-col3a1-mutation-present-with-pulmonary-complications-and-iliac-arterial-dissection
#3
Guangchao Gu, Hang Yang, Lijia Cui, Yuanyuan Fu, Fangda Li, Zhou Zhou, Yuehong Zheng
Vascular Ehlers-Danlos syndrome (vEDS) is a life-threatening connective tissue disorder due to its high tendency of arterial and organ rupture. Pulmonary complications in vEDS are rare. We present a young male patient with vEDS who developed severe pulmonary complications and severe rupture of the iliac artery at different stages of his life. Vascular Ehlers-Danlos syndrome was diagnosed based on clinical manifestations and confirmed by the identification of COL3A1 gene mutation. Due to high bleeding tendency and weak cardiopulmonary capacity, conservative treatment was taken for him...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29209615/simultaneous-hepatic-and-mesenteric-hydatid-disease-a-case-report
#4
Daniel Paramythiotis, Anestis Karakatsanis, Petros Bangeas, Konstantinia Kofina, Vassileios Papadopoulos, Stylianos Apostolidis, Antonios Michalopoulos
Introduction: Hydatid cysts most commonly present in the liver and the lungs; however, they can appear more rarely in other locations, such as the mesentery, with a rather unclear mechanism of manifestation. Herein, we present a case of simultaneous presence of hydatid cysts in the liver and the mesentery of a young man. Case report: A 39-year-old man was referred to our Department for further investigation of intermittent abdominal pain, especially in the right upper quadrant, and abdominal distension...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29204236/hydatid-cyst-presented-as-a-subcutaneous-thigh-mass
#5
Leyla Acu, Berat Acu, Rusen Acu, S Ahmet Sahin
Hydatid disease is an endemic zoonosis, and patients are generally from cattle- and sheep-raising regions of the world, such as Central Europe, the Mediterranean, the Middle East, China, South America, Australia, New Zealand, South Africa, and Russia (Lewall and McCorkell in Radiology 155:773-775, 1985). Furthermore, hydatid cyst is a disease of immigrants in non-endemic countries and in developed countries (Stojkovic et al. in PLoS Negl Trop Dis 6:e1880, 2012). The most common affected organs are liver and lungs...
December 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/29201483/purulent-appearing-material-in-an-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-of-mediastinal-lymph-node-a-diagnostic-challenge
#6
Damaris Pena, Gilda Diaz-Fuentes, Sindhaghatta Venkatram
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has increasingly been performed for the diagnosis and staging of thoracic malignancies. Findings of a necrotic lymph node raise concern for infectious process and malignancy. A hypoechoic area on ultrasound/EBUS within a lymph node without blood flow is suggestive of pathologies like infections or malignancy. Inspection of the fluid could suggest a diagnosis; clear aspirates usually suggest bronchogenic or mediastinal cysts and purulent material suggests abscesses or necrotic lymph nodes...
2017: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/29197847/perforated-neuroenteric-cyst-masquerading-as-congenital-pulmonary-airway-malformation
#7
Sreekar Gundapaneni, Vishesh Jain, Shilpa Sharma, Devendra Kumar Gupta
A 3-month-old child was presented with haemoptysis with respiratory distress. Imaging was suggestive of a cavitary lesion in the lung with surrounding consolidation. Diagnosis of a primary lung pathology like congenital pulmonary airway malformation was considered. Based on clinical suspicion and prior experience, a Tc-99m pertechnetate radionuclide study was performed, which clinched the diagnosis of foregut duplication cyst. Intraoperative findings confirmed the presence of a neuroenteric cyst. The child remains asymptomatic on follow-up awaiting neurosurgical intervention for the intraspinal component of the cyst...
December 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29184259/isolated-peritoneal-mesenteric-and-omental-hydatid-cyst-a-clinicopathologic-narrative-review
#8
REVIEW
Bita Geramizadeh
Hydatid disease (HD) is caused by Echinococcus granulosus and is endemic in many parts of the world. This parasitic tapeworm can produce cysts in almost every organ of the body, with the liver and lung being the most frequently targeted organs. Peritoneum, omentum, and mesentery are among these unusual locations, which can cause diagnostic challenge and treatment delay. This review provides information on the reported cases of the peritoneal, omental, and mesenteric hydatid cyst in the world during the last 20 years...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184009/disseminated-hydatid-cyst-of-liver-and-lung
#9
Nousheen Iqbal, Muhammad Hussain, Romana Idress, Muhammad Irfan
Hydatid cyst commonly affects liver followed by lung, but rarely affects both organs simultaneously. Here we presented a patient who presented with concurrent involvement of both lungs and liver. Patient presented with dyspnoea and generalised weakness with bilateral rounded opacities throughout the lung field of variable sizes. CT scan chest with contrast showed multiple rounded soft tissue density in both lungs and liver. Patient underwent mini thoracotomy which revealed multiple cystic lesions throughout lung...
November 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29183851/a-retrospective-study-of-human-cystic-echinococcosis-in-basrah-province-iraq
#10
Mohanad F Abdulhameed, Ihab Habib, Suzan A Al-Azizz, Ian Robertson
Human cystic echinococcosis (CE) is a parasitic zoonosis with serious clinical burden and constitutes a challenge to public health in endemic areas worldwide. We performed a retrospective study to investigate the occurrence of CE in patients at six hospitals in Basrah province, Iraq. In the current study setting, data retrieval and validation of the quality of hospital records was very challenging considering the difficult situation Iraq is unfortunately facing. Hospitalization records were reviewed from January 2005 to December 2015...
November 26, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29177384/-echinococcosis-hyper-endemic-and-cystic-fertility-in-pigs-of-the-inter-andean-valley-of-huancarama-peru
#11
Rony Sierra-Ramos, Aldo Valderrama-Pomé
The objective of the research was to determine the percentage of echinococcosis infection in swine, cystic fertility and associated factors. Cross-sectional study. The population was formed by 579 pigs slaughtered in the slaughterhouse of Huancarama. Hydatid cysts were detected by postmortem evaluation. Fertility was determined by measuring the diameter of the cysts and microscopically observing the germinative membrane in search of protoscoleces. The percentage of cystic echinococcosis infection was 76.7% (CI 95%: 73...
April 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29175081/epithelial-mesenchymal-crosstalk-influences-cellular-behavior-in-a-3d-alveolus-fibroblast-model-system
#12
Katherine J R Lewis, Jessica K Hall, Emi A Kiyotake, Tova Christensen, Vivek Balasubramaniam, Kristi S Anseth
Interactions between lung epithelium and interstitial fibroblasts are increasingly recognized as playing a major role in the progression of several lung pathologies, including cancer. Three-dimensional in vitro co-culture systems offer tissue-relevant platforms to study the signaling interplay between diseased and healthy cell types. Such systems provide a controlled environment in which to probe the mechanisms involved in epithelial-mesenchymal crosstalk. To recapitulate the native alveolar tissue architecture, we employed a cyst templating technique to culture alveolar epithelial cells on photodegradable microspheres and subsequently encapsulated the cell-laden spheres within poly (ethylene glycol) (PEG) hydrogels containing dispersed pulmonary fibroblasts...
November 15, 2017: Biomaterials
https://www.readbyqxmd.com/read/29169151/cystic-lung-disease-in-genetic-syndromes-with-deficient-tumor-suppressor-gene-function
#13
Cécile Daccord, Laurent P Nicod, Romain Lazor
Cystic lung diseases constitute a distinct group of rare lung disorders, among which two result from monogenic defects affecting tumor suppressor genes: lymphangioleiomyomatosis, either sporadic or associated with tuberous sclerosis complex, and Birt-Hogg-Dubé syndrome. These disorders have similarities in their clinical expression, including occurrence in young adults, multiple pulmonary cysts, recurrent pneumothorax, skin hamartomas, and renal tumors. However, they markedly differ in their gender distribution, pathogenesis, disease course, and prognosis...
November 23, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29157599/skin-lesions-of-birt-hogg-dub%C3%A3-syndrome-clinical-and-histopathological-findings-in-31-japanese-patients-who-presented-with-pneumothorax-and-or-multiple-lung-cysts
#14
Chikako Iwabuchi, Hiroki Ebana, Akira Ishiko, Azusa Negishi, Teruaki Mizobuchi, Toshio Kumasaka, Masatoshi Kurihara, Kuniaki Seyama
BACKGROUND: Birt-Hogg-Dubé syndrome (BHDS) (OMIM #135150) is an autosomal dominant disease, characterized by fibrofolliculomas (FFs) of the skin, pulmonary cysts with/without pneumothorax, and renal tumors. The prevalence of skin manifestations reported for Japanese BHDS patients is lower (<30%) compared with that of Western countries (75∼90%), which appear to be underestimated. OBJECTIVE: To precisely examine the prevalence of skin lesions with dermoscopy and histopathology with reference to genetic analyses...
November 2, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29145875/re-visiting-the-detection-of-porcine-cysticercosis-based-on-full-carcass-dissections-of-naturally-taenia-solium-infected-pigs
#15
Mwelwa Chembensofu, K E Mwape, I Van Damme, E Hobbs, I K Phiri, M Masuku, G Zulu, A Colston, A L Willingham, B Devleesschauwer, A Van Hul, A Chota, N Speybroeck, D Berkvens, P Dorny, S Gabriël
BACKGROUND: Taenia solium is a neglected zoonotic parasite. The performances of existing tools for the diagnosis of porcine cysticercosis need further assessment, and their shortcomings call for alternatives. The objective of this study was to evaluate the performance of tongue palpation and circulating antigen detection for the detection of porcine cysticercosis in naturally infected pigs of slaughter age compared to full carcass dissections (considered the gold standard). Additionally, alternative postmortem dissection procedures were investigated...
November 16, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143119/infectious-and-non-infectious-diseases-causing-the-air-crescent-sign-a-state-of-the-art-review
#16
REVIEW
Joyce Betta Sevilha, Rosana Souza Rodrigues, Miriam Menna Barreto, Gláucia Zanetti, Bruno Hochhegger, Edson Marchiori
Aspergilloma, also known as mycetoma or fungus ball, is characterized by a round or oval mass with soft-tissue attenuation within a preexisting lung cavity. The typical computed tomography (CT) aspect of an aspergilloma is a mass separated from the wall of the cavity by an airspace of variable size and shape, resulting in the air crescent sign, also known as the meniscus sign. This CT feature is non-specific and can be simulated by several other entities that result in intracavitary masses. This review describes the main clinical and imaging aspects of the infectious and non-infectious diseases that may present with fungus-ball appearance, including pulmonary hydatid cyst, Rasmussen aneurysm, pulmonary gangrene, intracavitary clot, textiloma, lung cancer, metastasis, and teratoma, focusing on the differential diagnosis...
November 15, 2017: Lung
https://www.readbyqxmd.com/read/29141314/-a-novel-compound-heterozygous-mutation-in-abca3-gene-in-a-child-with-diffuse-parenchymal-lung-disease
#17
Y M Bao, X L Liu, X L Liu, J H Chen, Y J Zheng
Objective: To summarize the clinical characteristics of the diffuse parenchymal lung diseases in a child caused by a novel compound heterozygous ABCA3 mutation and explore the association between the phenotype and ABCA3 mutation. Method: The clinical material of a patient diagnosed with diffuse parenchymal lung disease with ABCA3 mutation in December 2016 in Shenzhen Children's Hospital was analyzed. The information about ABCA3 gene mutation updated before April, 2017 was searched and collected from the gene databases (including 1000Genomes, HGMD, EXAC) and the literatures (including Wanfang Chinese database and Pubmed)...
November 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29114148/the-enzymes-and-electrolytes-profiles-in-hydatid-cyst-fluid-of-naturally-infected-iranian-domestic-ruminants
#18
Mohammad Yakhchali, Siamak Asri-Rezaie, Saeid Samimirad, Hadi Rezaie
Cystic echinoccoccosis is a zoonotic and prevalent disease which causes health problems and economic looses worldwide. The biochemical components of hydatid cyst fluid (HCF) have important role in metabolism and growth of unilocular hydatid cyst. The aim of the current study was to determine HCF level of enzymes and electrolytes profiles in naturally infected Iranian domestic ruminants. The livers and lungs infected with hydatid cysts were collected and HCF was aspirated from a total of 100 cysts obtained from livers (50 cysts) and lungs (50 cysts) of slaughtered domestic ruminants...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29114140/analysis-of-hospital-records-of-children-with-hydatid-cyst-in-south-of-iran
#19
Anahita Sanaei Dashti, Mohammad Rahim Kadivar, Abdolvahab Alborzi, Esmaeel Sadeghi, Gholam Reza Pouladfar, Neda Bagherian, Naser Honar, Masoomeh Khalifeh
The clinical manifestations of hydatidosis are various and related to anatomic location. Defining frequent symptoms and signs of the disease is imperative for early management of it. The aim of this report was to analyse the clinical features of infected children with hydatid cysts located in different organs. In this study, medical charts of 57 children between 3 and 16 years of age with hydatid cyst admitted to Pediatric Wards of Nemazee Hospital were evaluated over a 12 year period (from 2003 to 2014, prospectively)...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29114137/gross-and-histopathological-alterations-associated-with-cystic-echinococcosis-in-small-ruminants
#20
Akeel Bashir Beigh, Mohmommad Maqbool Darzi, Samina Bashir, Bisma Kashani, Aazima Shah, Showkat Ahmad Shah
Hydatidosis, an important parasitic zoonoses is a major public health as well as economic concern throughout the world. A total of 2100, sheep (2052) and goats (48), slaughtered or spontaneously dead, from various areas of Kashmir valley were screened for the presence of hydatidosis. Out of 2100 cases, 85 were positive for hydatidosis. The frequently infected organs were lungs and liver. The liver was observed to be the most frequently infected organ with relative prevalence of 61.17% followed by lungs (38...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
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