Capucine Baldini, Patricia Martin Romano, Andreea Varga, Stéphane Champiat, Sarah Dumont, Frédéric Dhermain, Guillaume Louvel, Aurélien Marabelle, Sophie Postel-Vinay, Eric Angevin, Anas Gazzah, Vincent Ribrag, Rastio Bahleda, Jean-Marie Michot, Antoine Hollebecque, Jean-Charles Soria, Christophe Massard
Targeting the immune system as a therapeutic strategy in solid tumors has shown great efficacy in various tumor types. However the role and success of this approach in glioblastomas remain to be determined. Recent studies demonstrated that central nervous system is no longer considered as an immunoprivileged sanctuary with impressive immune response without blood brain barrier's disruption. Improving our understanding of immune privilege in the central nervous system could lead to better treatment strategies in gliobastomas...
December 2018: Bulletin du Cancer