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https://www.readbyqxmd.com/read/28602839/epidemiology-of-brucellosis-in-iran-a-comprehensive-systematic-review-and-meta-analysis-study
#1
REVIEW
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucellosis is still one of the most challenging issues for health and the economy in many developing countries such as Iran. Considering the high prevalence of brucellosis, the aim of the current study was to systematically review published data about the annual incidence rate of this infection from different parts of Iran and provide an overall relative frequency (RF) for Iran using meta-analysis. We searched several databases including PubMed, ISI Web of Science, Scopus, google scholar, IranMedex and Iranian Scientific Information Database (SID) by using the following keywords: "Brucella", "Brucellosis", "Malta fever", "Mediterranean fever", "undulant fever", "zoonosis" and "Iran" in Title/Abstract/Keywords fields...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28601944/glucocorticoid-induced-leucine-zipper-expression-is-associated-with-response-to-treatment-and-immunoregulation-in-systemic-lupus-erythematosus
#2
Saeed Mohammadi, Mohammad Reza Ebadpour, Sima Sedighi, Mohsen Saeedi, Ali Memarian
Systemic lupus erythematosus (SLE) is an autoimmune disorder in which cytokine balance is disturbed. Glucocorticoids (GCs) are shown to balance immune response by transcriptional regulation of glucocorticoid receptor target genes such as Glucocorticoid-induced leucine zipper (GILZ) which has been introduced as an endogenous anti-inflammatory mediator. In the present study, we assessed the expression of GILZ in association with interferon-γ (IFN-γ), interleukine-10 (IL-10), and B lymphocyte stimulator (BLyS) plasma levels in SLE patients...
June 10, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28573922/determining-the-binding-site-and-binding-affinity-of-estradiol-to-human-serum-albumin-and-holo-transferrin-fluorescence-spectroscopic-isothermal-titration-calorimetry-and-molecular-modeling-approaches
#3
Nazila Danesh, Zahra Navaee Sedighi, Sima Beigoli, Atena Sharifi-Rad, Mohammad Reza Saberi, Jamshidkhan Chamani
The interactions between estradiol and two carrier proteins, i.e. human serum albumin (HSA) and holo-transferrin (HTF) in aqueous solution at pH = 7.4 were studied by three-dimensional fluorescence emission spectroscopy, isothermal titration calorimetry (ITC), zeta-potential, resonance light-scattering and molecular modeling. Extensive fluorescence quenching was observed throughout the interaction between the drug and both proteins. Moreover, conformational changes were determined by observing the rearrangement of Trp residues during binding of estradiol with HSA and HTF at different concentrations...
June 2, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28506887/molecular-investigation-of-virulence-factors-of-brucella-melitensis-and-brucella-abortus-strains-isolated-from-clinical-and-non-clinical-samples
#4
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucella is zoonotic pathogen that induces abortion and sterility in domestic mammals and chronic infections in humans called Malta fever. It is a facultative intracellular potential pathogen with high infectivity. The virulence of Brucella is dependent upon its potential virulence factors such as enzymes and cell envelope associated virulence genes. The aim of this study was to investigate the Brucella virulence factors among strains isolated from humans and animals in different parts of Iran. Seventy eight strains of Brucella species isolated from suspected human and animal cases from several provinces of Iran during 2015-2016 and identified by phenotypic and molecular methods...
May 12, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28299009/clinical-practice-guidelines-for-prevention-diagnosis-and-management-of-early-and-delayed-onset-ocular-injuries-due-to-mustard-gas-exposure
#5
Zhale Rajavi, Sare Safi, Mohammad Ali Javadi, Mohammad Reza Jafarinasab, Sepehr Feizi, Mohammadreza Sedighi Moghadam, Khosrow Jadidi, Mahmoud Babaei, Armin Shirvani, Alireza Baradaran-Rafii, Hossein Mohammad-Rabei, Hossein Ziaei, Mohammad Ghassemi-Broumand, Siamak Delfaza Baher, Mostafa Naderi, Mahmoodreza Panahi-Bazaz, Siamak Zarei-Ghanavati, Shahriar Hanjani, Hassan Ghasemi, Ramin Salouti, Mojgan Pakbin, Bahareh Kheiri
PURPOSE: To develop clinical practice guidelines (CPGs) for prevention, diagnosis, treatment and follow-up of ocular injuries caused by exposure to mustard gas. METHODS: The clinical questions were designed by the guideline team. Websites and databases including National Guidelines Clearinghouse, National Institute for Clinical Excellence, Cochrane, and PubMed were searched to find related CPGs and explore possible answers to the clinical questions. Since there were no relevant CPGs in the literature, related articles in Persian and English languages were extracted...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28216445/labial-pain-swelling-and-fever-an-autoinflammatory-disorder
#6
Ethan T Craig, Reza Sedighi Manesh, Jonathan D Cuda, Allan C Gelber
No abstract text is available yet for this article.
February 16, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28197394/antibiogram-of-bacteria-isolated-from-automated-teller-machines-in-hamadan-west-iran
#7
Hassan Mahmoudi, Mohammad Reza Arabestani, Mohammad Yousef Alikhani, Iraj Sedighi, Hamed Farhadi Kohan, Mohammad Molavi
Aim: Bacteria are ubiquitous in the environment. In keeping with the continued expansion of urbanization and the growing population, an increasing number of people use automated banking, i.e. automated teller machines (ATMs). The aim of this study was to investigate the bacterial contamination and its antibiotic sensitivity on computer keyboards located at ATMs in Hamadan province, Iran. Method: Out of 360 ATMs at four locations in Hamadan, 96 were randomly selected for this study. The antibiotic susceptibility pattern of all isolates was determined by the agar disk diffusion method using gentamicin (10 µg), vancomycin (30 µg), trimethoprim/sulfamethoxazole (25 µg), amikacin (30 µg), tobramycin (10 µg), cephalotin (30 µg), norfloxacin (5 µg), and ceftizoxim (30 µg) disks...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/27888588/lps-responsive-beige-like-anchor-gene-mutation-associated-with-possible-bronchiolitis-obliterans-organizing-pneumonia-associated-with-hypogammaglobulinemia-and-normal-igm-phenotype-and-low-number-of-b-cells
#8
Sima Shokri, Mohammad Nabavi, Tatjana Hirschmugl, Asghar Aghamohammadi, Saba Arshi, Mohamad Hassan Bemanian, Morteza Fallahpour, Rasool Molatefi, Mahsa Rekabi, Narges Eslami, Javad Ahmadian, Kian Darabi, Gholam Reza Sedighi, Maryam Monajemzadeh, Mohammadreza Modaresi, Nima Parvaneh, Kaan Boztug, Nima Rezaei
LPS-Responsive Beige-like Anchor (LRBA) deficiency is a disease which has recently been described in a group of patients with common variable immunodeficiency (CVID) in association with autoimmunity and/or inflammatory bowel disease (IBD)-like phenotype. We here describe a 10-year-old boy who experienced recurrent infections, mainly in the respiratory system, associated with thrombocytopenia and anemia. Immunological workup showed low numbers of B cells and low IgG, but normal IgM levels. In spite of therapeutic doses of antibiotics, antivirals, and antifungal agents, in addition to immunoglobulin replacement therapy, he developed disseminated involvement of both lungs with peripheral nodules; transbronchial lung biopsy revealed possible bronchiolitis obliterans organizing pneumonia (BOOP)...
October 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27871917/gonococcal-conjunctivitis-a-case-report-of-an-unusual-mode-of-transmission
#9
Anna Jo Bodurtha Smith, Samuel B Holzman, Reza Sedighi Manesh, Trish M Perl
BACKGROUND: Outside of the newborn period, development of gonococcal conjunctivitis is rare and predominantly occurs through autoinoculation. We report an unusual case of gonococcal conjunctivitis in a young woman exposed through direct inoculation. CASE: A 19-year-old woman presented with purulent ocular discharge, severe pain, and decreased vision unresponsive to topical antibiotics or ganciclovir approximately 3 weeks after accidental ocular exposure to seminal fluid during unprotected oral sex...
November 18, 2016: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27612485/carotid-cavernous-fistula
#10
Christopher R Bailey, Nikhilesh Ray-Mazumder, Reza Sedighi Manesh
No abstract text is available yet for this article.
April 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27539653/the-missing-element
#11
REVIEW
Molly E Anderson, Katherine L DeNiro, Brian J Harte, Reza Sedighi Manesh
No abstract text is available yet for this article.
December 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/27486087/factoring-in-the-missing-link
#12
Nilay Sethi, Reza Sedighi Manesh, Adam Sperling, Scott C Bresler, Nathan T Connell, Lawrence M Tierney
No abstract text is available yet for this article.
January 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/27356654/efficacy-and-safety-of-levetiracetam-in-the-management-of-seizures-in-neonates
#13
Mostafa Sedighi, Farzaneh Asadi, Nasrin Moradian, Mazyar Vakiliamini, Mohamad Moradian
OBJECTIVE: To evaluate the efficacy and safety of levetiracetam (LEV) in the management of seizures in neonates. METHODS: A prospective non-blind, single arm clinical trial conducted in the Department of Neonatology and Pediatric Intensive Care, Mohamad Kermanshahi, and Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran from May 2014 to December 2014. Fifty out of 60 newborns with gestational age >/=30 weeks with clinically diagnosed seizures were included...
July 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27162861/epidemiological-and-clinical-features-of-cervical-column-and-cord-injuries-a-2-year-experience-from-a-large-trauma-center-in-southern-iran
#14
Hamid Reza Kamravan, Ali Haghnegahdar, Shahram Paydar, Mohamad Khalife, Mahsa Sedighi, Fariborz Ghaffarpasand
OBJECTIVE: To describe the epidemiological characteristics of patients with cervical spine injury admitted to Rajaee hospital, Shiraz, Iran. METHODS: This cross-sectional study includes all patients admitted with impression of cervical column injury with or without cervical cord injury from October 2009 to March 2012 to our level I trauma center in Shiraz. We recorded the patients' characteristics including age, sex, marital status, mechanism of injury, level of injury, concomitant injury, treatment(non-operative or operative) and clinical outcome...
January 2014: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27123904/effects-of-antioxidants-catalase-and-%C3%AE-tocopherol-on-cell-viability-and-oxidative-stress-variables-in-frozen-thawed-mice-spermatogonial-stem-cells
#15
Freshte Aliakbari, Mohamad Ali Sedighi Gilani, Hossein Yazdekhasti, Morteza Koruji, Hamid Reza Asgari, Maryam Baazm, Fariborz Izadyar, Ebrahim Kharrazi Nejad, Maryam Khanezad, Mehdi Abbasi
Cryopreservation of spermatogonial stem cells is considered as a useful procedure for preserving fertility in children with testis cancer. SSCs were isolated from testes mice, and then antioxidant was added to the freezing medium. The Bax expression level in antioxidant groups was significantly (P ≤ 0.05) lower than the control group and a significant rise of Bcl2 expression was detected in the antioxidant groups. ROS production with antioxidant was significantly lower compared with the control group...
February 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/26923893/surveillance-of-antibiotic-consumption-point-prevalence-survey-2014-antimicrobial-prescribing-in-pediatrics-wards-of-16-iranian-hospitals
#16
MULTICENTER STUDY
Alireza Fahimzad, Zahra Eydian, Abdollah Karimi, Farideh Shiva, Shirin Sayyahfar, Manijeh Kahbazi, Aliakbar Rahbarimanesh, Iraj Sedighi, Reza Arjmand, Gholamreza Soleimani, Anahita Sanaei Dashti, Babak Abdinia, Nasser Mostafavi, Roya Nikfar, Masomeh Abedini, Mohammad Sadegh Rezaei, Ali Mohammadpour, Houman Hashemian, Hossein Hidari, Keyghobad Ghadiri, Reza Entezari Heravi
BACKGROUND: Antibiotics are among the most commonly prescribed drugs in pediatrics. Due to lack of uniformity in pediatric antimicrobial prescribing and the emergence of antibiotic resistance, appropriate drug utilization studies have been found to be crucial to evaluate whether these drugs are properly used. METHODS: Data were collected between January 2014 and February 2014 in 16 Iranian pediatric hospitals using a standardized method. The point prevalence survey included all inpatient beds...
March 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/26892322/diffuse-alveolar-hemorrhage-blood-sweat-and-tears
#17
Kreshnik Zejnullahu, Shabnam Khatami, Reza Sedighi Manesh
No abstract text is available yet for this article.
July 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/26421128/dissemination-of-extended-spectrum-%C3%AE-lactamases-and-quinolone-resistance-genes-among-clinical-isolates-of-uropathogenic-escherichia-coli-in-children
#18
Iraj Sedighi, Mohammad Reza Arabestani, Ali Rahimbakhsh, Zahra Karimitabar, Mohammad Yousef Alikhani
BACKGROUND: Urinary tract infection (UTI) is one of the most common childhood bacterial infections and Escherichia coli is the major pathogen. Producing β-lactamase enzymes are the most common mechanism of bacterial resistance. OBJECTIVES: This study aimed to determine the prevalence of Extended-Spectrum β-Lactamases (ESBLs) and Quinolone Resistance (qnr) genes in E. coli strains isolated from UTIs. MATERIALS AND METHODS: In this study, a total of 120 isolates of E...
July 2015: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/26307386/diagnostic-scheming
#19
Marlene Martin, Reza Sedighi Manesh, Mark C Henderson, Jeffrey M Critchfield
No abstract text is available yet for this article.
December 2015: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/26063201/sutton-s-law-keep-going-where-the-money-is
#20
Satoshi Watanuki, Hitoshi Honda, Nobuyoshi Minemura, Reza Sedighi Manesh, Didier Raoult, Yasuharu Tokuda
No abstract text is available yet for this article.
November 2015: Journal of General Internal Medicine
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