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Fernando velayos

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https://www.readbyqxmd.com/read/27765687/changing-paradigms-in-detection-of-dysplasia-and-management-of-patients-with-inflammatory-bowel-disease-is-colectomy-still%C3%A2-necessary
#1
Fernando Velayos, Priya Kathpalia, Emily Finlayson
This review chronicles the evolution of dysplasia detection and management in inflammatory bowel disease since 1925, the year the first case report of colitis-related colorectal cancer was published. We have grouped advances in colorectal cancer research, endoscopic techniques, surgery, and technology into 4 unequally timed eras, before colonoscopy, early era of colonoscopy, new century, and 2017 and beyond. We conclude that colorectal cancer prevention and dysplasia management for patients with inflammatory bowel disease has changed during these periods, from somewhat hopeless to hopeful...
October 17, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27189916/appropriateness-of-testing-for-anti-tumor-necrosis-factor-agent-and-antibody-concentrations-and-interpretation-of%C3%A2-results
#2
Gil Y Melmed, Peter M Irving, Jennifer Jones, Gilaad G Kaplan, Patricia L Kozuch, Fernando S Velayos, Leonard Baidoo, Miles P Sparrow, Brian Bressler, Adam S Cheifetz, Shane M Devlin, Laura E Raffals, Niels Vande Casteele, Diane R Mould, Jean-Fred Colombel, Marla Dubinsky, William J Sandborn, Corey A Siegel
BACKGROUND & AIMS: The availability of tests for blood concentrations of anti-tumor necrosis factor (TNF) agents and antibodies against these drugs could improve dose selection for patients with inflammatory bowel disease (IBD). However, there is little consensus on when to test and how to interpret test results. We used the RAND/UCLA Appropriateness Method to determine when these tests are appropriate and how to clinically interpret their results. METHODS: We conducted a systematic literature search in November 2013 to identify observational or experimental studies of the measurement of anti-TNF drug and antibody concentrations in patients with IBD and interpretation of their results...
September 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27057680/recommendations-for-quality-colonoscopy-reporting-for-patients-with-inflammatory-bowel-disease-results-from-a-rand-appropriateness-panel
#3
Shane M Devlin, Gil Y Melmed, Peter M Irving, David T Rubin, Asher Kornbluth, Patricia L Kozuch, Laura E Raffals, Fernando S Velayos, Miles P Sparrow, Leonard Baidoo, Brian Bressler, Adam S Cheifetz, Jennifer Jones, Gilaad G Kaplan, Corey A Siegel
BACKGROUND: Consensus on what constitutes a quality colonoscopy report for patients with inflammatory bowel disease (IBD) is lacking. We developed a template for quality colonoscopy reporting that can be used broadly by endoscopists. METHODS: After a literature review of topics relevant to colonoscopy reporting, members of the Building Research in Inflammatory Bowel Disease Globally (BRIDGe) group and 2 external experts proposed candidate reporting elements. The RAND/University of California, Los Angeles appropriateness method was applied to rate the importance and feasibility of elements for inclusion in colonoscopy reports for patients with IBD...
June 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/26364967/a-roadmap-to-the-implementation-of-chromoendoscopy-in-inflammatory-bowel-disease-colonoscopy-surveillance-practice
#4
Silvia Sanduleanu, Tonya Kaltenbach, Alan Barkun, Robert P McCabe, Fernando Velayos, Michael F Picco, Loren Laine, Roy Soetikno, Kenneth R McQuaid
No abstract text is available yet for this article.
January 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26142167/effects-of-concomitant-immunomodulator-therapy-on-efficacy-and-safety-of-anti-tumor-necrosis-factor-therapy-for-crohn-s-disease-a-meta-analysis-of-placebo-controlled-trials
#5
REVIEW
Jennifer L Jones, Gilaad G Kaplan, Laurent Peyrin-Biroulet, Leonard Baidoo, Shane Devlin, Gil Y Melmed, Divine Tanyingoh, Laura Raffals, Peter Irving, Patricia Kozuch, Miles Sparrow, Fernando Velayos, Brian Bressler, Adam Cheifetz, Jean-Frederic Colombel, Corey A Siegel
BACKGROUND & AIMS: There is debate over whether patients with Crohn's disease who start anti-tumor necrosis factor (TNF) therapy after failed immunomodulator therapy should continue to receive concomitant immunomodulators. We conducted a meta-analysis of subgroups from randomized controlled trials (RCTs) of anti-TNF agents to compare the efficacy and safety of concomitant immunomodulator therapy vs anti-TNF monotherapy. METHODS: We performed a systematic review of literature published from 1980 through 2008 and identified 11 RCTs of anti-TNF agents in patients with luminal or fistulizing Crohn's disease...
December 2015: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/25721001/colorectal-cancer-screening-and-surveillance-in-the-elderly-updates-and-controversies
#6
REVIEW
Lukejohn W Day, Fernando Velayos
Colorectal cancer is common worldwide, and the elderly are disproportionately affected. Increasing age is a risk factor for the development of precancerous adenomas and colorectal cancer, thus raising the issue of screening and surveillance in older patients. Elderly patients are a diverse and heteroge-neous group, and special considerations such as comorbid medical conditions, functional status and cognitive ability play a role in deciding on the utility of screening and sur-veillance. Colorectal cancer screening can be beneficial to patients, but at certain ages and under some circumstances the harm of screening outweighs the benefits...
March 2015: Gut and Liver
https://www.readbyqxmd.com/read/25325227/braden-scale-and-norton-scale-modified-by-insalud-in-an-acute-care-hospital-validity-and-cutoff-point
#7
Jose M González-Ruiz, Tomas Sebastián-Viana, Marta E Losa-Iglesias, Isabel Lema-Lorenzo, Fernando J Núñez Crespo, Gema Martín-Merino, Maria R García-Martín, Eva Velayos-Rodríguez, Carmen G Nogueiras-Quintas
OBJECTIVE: The objective of this article was to determine the most suitable cutoff point (CP) for the Braden Scale and Norton Modified Scale by INSALUD Scale (Norton-MI) in an acute care hospital. DESIGN: The authors have designed a prospective, descriptive study of patients from their hospital. From December 2008 to March 2009, a nurse collected and recorded adult patient data daily, including the appearance of pressure ulcers. PATIENTS: Adult patients in medical and surgical wards...
November 2014: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/24975529/quality-bowel-preparation-for-surveillance-colonoscopy-in-patients-with-inflammatory-bowel-disease-is-a-must
#8
REVIEW
Andrew Nett, Fernando Velayos, Kenneth McQuaid
Colonoscopy is routinely performed in patients with inflammatory bowel disease (IBD) for surveillance of dysplasia. Thorough bowel preparation is necessary to facilitate lesion detection. Patients with IBD do not have poorer bowel preparation outcomes but may have decreased preparation tolerance affecting adherence to surveillance protocols. A low-fiber prepreparation diet may improve preparation tolerance without affecting preparation quality. The standard preparation regimen should consist of split-dose administration of a polyethylene glycol-based purgative...
July 2014: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/24938590/colorectal-cancer-of-the-elderly
#9
Lukejohn W Day, Fernando Velayos
Colorectal cancer (CRC) disproportionately affects the elderly. Older age is a strong risk factor for both the development of precancerous adenomas and CRC, thus raising the issue of screening and surveillance in older patients. However, screening and surveillance decisions in the elderly can be complex and challenging. Elderly patients are a diverse and heterogeneous group and special considerations such as co-morbid medical conditions, functional status, and cognitive ability play a role in one's decisions regarding the utility of screening and surveillance...
September 2014: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/24282056/on-the-question-of-ethnicity-and-its-impact-on-ibd-related-outcomes
#10
EDITORIAL
Caroline Hwang, Fernando Velayos
No abstract text is available yet for this article.
January 2014: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/24280882/challenges-in-designing-a-national-surveillance-program-for-inflammatory-bowel-disease-in-the-united-states
#11
REVIEW
Millie D Long, Susan Hutfless, Michael D Kappelman, Hamed Khalili, Gilaad G Kaplan, Charles N Bernstein, Jean Frederic Colombel, Corinne Gower-Rousseau, Lisa Herrinton, Fernando Velayos, Edward V Loftus, Geoffrey C Nguyen, Ashwin N Ananthakrishnan, Amnon Sonnenberg, Andrew Chan, Robert S Sandler, Ashish Atreja, Samir A Shah, Kenneth J Rothman, Neal S Leleiko, Renee Bright, Paolo Boffetta, Kelly D Myers, Bruce E Sands
This review describes the history of U.S. government funding for surveillance programs in inflammatory bowel diseases (IBD), provides current estimates of the incidence and prevalence of IBD in the United States, and enumerates a number of challenges faced by current and future IBD surveillance programs. A rationale for expanding the focus of IBD surveillance beyond counts of incidence and prevalence, to provide a greater understanding of the burden of IBD, disease etiology, and pathogenesis, is provided. Lessons learned from other countries are summarized, in addition to potential resources that may be used to optimize a new form of IBD surveillance in the United States...
February 2014: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/24267607/colorectal-cancer-and-the-elderly
#12
REVIEW
Lukejohn W Day, Fernando Velayos
Colorectal cancer and precancerous adenomas disproportionately affect the elderly, necessitating the need for screening and surveillance in this group. However, screening and surveillance decisions in the elderly can be challenging. Special considerations such as comorbid medical conditions, functional status, and cognitive ability play a role in one's decisions regarding the utility of screening and surveillance as well as the success and safety of various screening modalities. This article explores the evidence for screening and surveillance in the elderly, and addresses key challenges unique to this population...
February 2014: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/24183955/avoiding-rash-decision-making-skin-cancer-screening-of-patients-with-inflammatory-bowel-disease
#13
EDITORIAL
Derrick Siao, Fernando Velayos
No abstract text is available yet for this article.
February 2014: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/24173809/racial-and-ethnic-differences-in-health-care-utilization-and-outcomes-among-ulcerative-colitis-patients-in-an-integrated-health-care-organization
#14
COMPARATIVE STUDY
Dan Li, Bernadette Collins, Fernando S Velayos, Liyan Liu, James D Lewis, James E Allison, Nicole T Flowers, Susan Hutfless, Oren Abramson, Lisa J Herrinton
BACKGROUND: Current knowledge of racial disparities in healthcare utilization and disease outcomes for ulcerative colitis (UC) is limited. We sought to investigate these differences among Caucasian, African American, Asian, and Hispanic patients with ulcerative colitis in Kaiser Permanente, a large integrated health-care system in Northern California. METHODS: This retrospective cohort study used computerized clinical data from 5,196 Caucasians, 387 African-Americans, 550 Asians, and 801 Hispanics with prevalent UC identified between 1996 and 2007...
February 2014: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/24091907/serologic-markers-associated-with-development-of-crohn-s-disease-after-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#15
Brindusa Truta, Dan X Li, Uma Mahadevan, Elena R Fisher, Yunn-Y Chen, Kim Grace, Fernando Velayos, Jonathan P Terdiman
BACKGROUND AND AIMS: One of the causes of pouch failure after ileal pouch anal anastomosis (IPAA) for ulcerative colitis (UC) is the development of de novo Crohn's disease (CD). Our aim was to clearly define factors associated with post-IPAA CD. METHODS: We conducted a cross-sectional study to compare demographic, clinical, and serological characteristics of patients with and without post-IPAA CD. All subjects underwent testing for anti-neutrophil cytoplasm antibodies, anti-Saccaromyces cerevisiae antibodies, anti-outer membrane porin C antibodies, and anti-CBir1 flagellin (anti-CBir1)...
January 2014: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/23727492/looking-forward-to-understanding-and-reducing-colorectal-cancer-risk-in-inflammatory-bowel-disease
#16
EDITORIAL
Fernando S Velayos, Thomas A Ullman
No abstract text is available yet for this article.
July 2013: Gastroenterology
https://www.readbyqxmd.com/read/23357488/a-test-based-strategy-is-more-cost-effective-than-empiric-dose-escalation-for-patients-with-crohn-s-disease-who-lose-responsiveness-to-infliximab
#17
Fernando S Velayos, James G Kahn, William J Sandborn, Brian G Feagan
BACKGROUND & AIMS: Patients with Crohn's disease who become unresponsive to therapy with tumor necrosis factor antagonists are managed initially with either empiric dose escalation or testing-based strategies. The comparative cost effectiveness of these 2 strategies is unknown. We investigated whether a testing-based strategy is more cost effective than an empiric dose-escalation strategy. METHODS: A decision analytic model that simulated 2 cohorts of patients with Crohn's disease compared outcomes for the 2 strategies over a 1-year time period...
June 2013: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/22623078/systematic-review-the-role-of-race-and-socioeconomic-factors-on-ibd-healthcare-delivery-and-effectiveness
#18
REVIEW
Justin L Sewell, Fernando S Velayos
BACKGROUND: Race and socioeconomic status (SES) significantly affect the content and delivery of healthcare for multiple chronic disease states. Inflammatory bowel disease (IBD) is a set of complex, chronic diseases with the potential for significant morbidity if the content or delivery of healthcare is suboptimal. However, the literature related to race, SES, and IBD remains fragmented. METHODS: Using guidelines published by the Centre for Reviews and Dissemination, we performed a systematic review of the world's literature to identify studies related to: 1) IBD, 2) race/ethnicity, 3) SES, 4) healthcare delivery, and 5) healthcare effectiveness...
March 2013: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/22609382/incidence-and-mortality-of-colorectal-adenocarcinoma-in-persons-with-inflammatory-bowel-disease-from-1998-to-2010
#19
Lisa J Herrinton, Liyan Liu, Theodore R Levin, James E Allison, James D Lewis, Fernando Velayos
BACKGROUND & AIMS: The relationship between inflammatory bowel disease (IBD) and the incidence and mortality of colorectal adenocarcinoma (CRC) has not been evaluated recently. METHODS: We calculated the incidence and standardized incidence and mortality rate ratios of CRC among adult individuals with intact colons using Kaiser Permanente of Northern California's database of members with IBD and general membership data for the period of 1998 to June 2010 (data through 2008 were used to calculate mortality)...
August 2012: Gastroenterology
https://www.readbyqxmd.com/read/22537371/radiation-enteritidis-diagnosed-by-wireless-capsule-endoscopy
#20
María Lourdes Ruiz-Rebollo, Fernando de-la-Calle, Benito Velayos, Luis Fernández-Salazar, Rocío Aller-de-la-Fuente, José Manuel González
No abstract text is available yet for this article.
April 2012: Revista Española de Enfermedades Digestivas
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