keyword
MENU ▼
Read by QxMD icon Read
search

acute pancreatitis

keyword
https://www.readbyqxmd.com/read/29678717/a-tandem-mass-tag-tmt-proteomic-analysis-during-the-early-phase-of-experimental-pancreatitis-reveals-new-insights-in-the-disease-pathogenesis
#1
Violeta García-Hernández, Carmen Sánchez-Bernal, Domitille Schvartz, José J Calvo, Jean-Charles Sanchez, Jesús Sánchez-Yagüe
Changes in the protein expression occurring within the initiation phase of acute pancreatitis (AP) might be vital in the development of this complex disease. However, the exact mechanisms involved in the onset of AP remains elusive and most of our knowledge about the pathobiology of AP comes from animal models. We performed in a rat pancreatitic model a high-throughput shotgun proteomic profiling of the soluble and whole membrane fractions from the pancreas during the early phase of cerulein (Cer)-induced AP...
April 17, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29678582/reversion-of-aging-related-dheas-decline-in-mouse-plasma-alleviates-aging-related-glucose-tolerance-impairment-by-potentiation-of-glucose-stimulated-insulin-secretion-of-acute-phase
#2
Junlei Ma, Jiang Yue, Rong Huang, Yu Liao, Shengxian Li, Wei Liu
AIMS/HYPOTHESIS: The latest research proposes mild age-related diabetes (MARD) as a subgroup of type 2 diabetes. While in human circulating dehydroepiandrosterone sulfate (DHEAS) decline with age is related to MARD, the role of circulating DHEAS in insulin secretion remains little known. METHODS: After intraperitoneal administration of glucose (2 g/kg) together with DHEAS (50 μg/kg) or equivalent DMSO to young (6-8 week old) or aging (12 month old) male C57BL/6 mice, plasma DHEAS and blood glucose were measured at indicated time point...
April 17, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29675786/the-microbiology-of-infected-pancreatic-necrosis-in-the-era-of-minimally-invasive-therapy
#3
Nadav Sahar, Richard A Kozarek, Zaheer S Kanji, Shingo Chihara, S Ian Gan, Shayan Irani, Michael Larsen, Andrew S Ross, Michael Gluck
We aimed to determine the microbiology of infected walled-off pancreatic necrosis (WON) in an era of minimally invasive treatment, since current knowledge is based on surgical specimens performed over two decades ago. We retrospectively analyzed a prospectively maintained database of patients who were treated for symptomatic WON using combined endoscopic and percutaneous drainage between 2008 and 2017. Aspirates from WON at initial treatment were evaluated. One hundred eighty-two patients were included with a mean age of 56 of whom 67% were male...
April 19, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29672966/rhubarb-combined-with-trypsin-inhibitor-for-severe-acute-pancreatitis-a-systematic-review-and-meta-analysis
#4
REVIEW
Jing Hu, Peilin Li, Tao Zhang
The objective of this study is to evaluate the efficacy and safety of rhubarb combined with trypsin inhibitor for severe acute pancreatitis (SAP). This meta-analysis was performed in accordance with the Transparent Reporting of Systematic Reviews and Meta-analysis protocol (PRISMA-P) and Cochrane Handbook. Relevant studies from inception to 2016 were searched through 7 related databases. The Cochrane Library was searched to assess the bias of the included trials. Data were analysed with Review Manager 5.3 software...
April 19, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29672416/determinants-of-severity-in-acute-pancreatitis-a-nation-wide-multicenter-prospective-cohort-study
#5
Hanna Sternby, Federico Bolado, Héctor J Canaval-Zuleta, Carlos Marra-López, Ana I Hernando-Alonso, Adolfo Del-Val-Antoñana, Guillermo García-Rayado, Robin Rivera-Irigoin, Francisco J Grau-García, Lluís Oms, Judith Millastre-Bocos, Isabel Pascual-Moreno, David Martínez-Ares, Juan A Rodríguez-Oballe, Antonio López-Serrano, María L Ruiz-Rebollo, Alejandro Viejo-Almanzor, Belén González-de-la-Higuera, Aitor Orive-Calzada, Ignacio Gómez-Anta, José Pamies-Guilabert, Fátima Fernández-Gutiérrez-Del-Álamo, Isabel Iranzo-González-Cruz, Mónica E Pérez-Muñante, María D Esteba, Ana Pardillos-Tomé, Pedro Zapater, Enrique de-Madaria
OBJECTIVE: The aim of this study was to compare and validate the different classifications of severity in acute pancreatitis (AP) and to investigate which characteristics of the disease are associated with worse outcomes. SUMMARY OF BACKGROUND DATA: AP is a heterogeneous disease, ranging from uneventful cases to patients with considerable morbidity and high mortality rates. Severity classifications based on legitimate determinants of severity are important to correctly describe the course of disease...
April 18, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29672331/tigecycline-associated-acute-pancreatitis
#6
Sana Akhter, Prathik Krishnan, Pratibha Kaul
No abstract text is available yet for this article.
April 10, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29671058/transcatheter-arterial-embolization-for-bleeding-peptic-ulcers-a-multicenter-study
#7
Stavros Spiliopoulos, Riccardo Inchingolo, Pierleone Lucatelli, Roberto Iezzi, Athanasios Diamantopoulos, Alessandro Posa, Bryan Barry, Carmelo Ricci, Marco Cini, Chrysostomos Konstantos, Konstantinos Palialexis, Lazaros Reppas, Artemis Trikola, Michele Nardella, Andreas Adam, Elias Brountzos
PURPOSE: To investigate the outcomes of transcatheter arterial embolization (TAE) for the treatment of peptic ulcer bleeding (PUB). MATERIALS AND METHODS: This is a retrospective, multicenter study, which investigated all patients who underwent TAE for the treatment of severe upper gastrointestinal hemorrhage from peptic ulcers in five European centers, between January 1, 2012 and May 1, 2017. All patients had undergone failed endoscopic hemostasis. Forty-four patients (male; mean age 74...
April 18, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29669309/emodin-ameliorates-ulcerative-colitis-by-the-flagellin-tlr5-dependent-pathway-in-mice
#8
Shuang Luo, Xiangliang Deng, Qi Liu, Zengfeng Pan, Zhongxiang Zhao, Lian Zhou, Xia Luo
Emodin is an anthraquinone compound derived from Rheum officinale Baill. Several reports showed that emodin had efficacy on acute pancreatitis, keratitis, myocarditis, and rheumatoid arthritis. However, the potency of emodin on ulcerative colitis(UC) remains unclear. In this study, we investigated the effect of emodin on dextran sodium sulfate (DSS)-induced ulcerative colitis in mice. Our results showed that emodin significantly alleviated the symptoms of DSS-induced UC in mice, involving prevented the loss of body weight and colon shortening, decreased the disease activity index (DAI), intestinal damages and the count of white blood cells (WBC) in peripheral blood...
April 15, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29668665/combination-of-electronic-choledochoscopy-and-holmium-laser-lithotripsy-for-complicated-biliary-calculus-treatment-a-new-exploration
#9
Zhong-Kai Ni, Hai-Min Jin, Xiao-Wen Li, Ye Li, Hai Huang
The safety and efficacy of the combination of electronic choledochoscopy and holmium laser lithotripsy for complicated bile duct stones were assessed. In total, 20 patients participated in this study, which was conducted between 2012 and 2017. None of the patients were candidates for endoscopic retrograde cholangiopancreatography with stone extraction. Outcome measures included complete stone clearance and complications postprocedure. Mean stone size was 17±5.2 mm (8 to 30 mm) and mean number of stones was 1...
April 17, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29667750/association-between-body-mass-index-and-pancreatitis-in-children-with-acute-lymphoblastic-leukemia
#10
Pernille R Mogensen, Benjamin O Wolthers, Kathrine Grell, Kjeld Schmiegelow, Thomas L Frandsen
No abstract text is available yet for this article.
April 18, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29667415/rectal-diclofenac-does-not-prevent-post-ercp-pancreatitis-in-consecutive-high-risk-and-low-risk-patients
#11
Lourdes Del Olmo Martínez, Benito Velayos Jiménez, Ana Almaraz Gómez
OBJECTIVE: rectal diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that is used to prevent pancreatitis in high-risk patients during endoscopic retrograde cholangiopancreatography (ERCP). The European Society of Gastrointestinal Endoscopy (ESGE) recommends the use of prophylaxis with indomethacin or diclofenac in all patients undergoing ERCP, including those at low or intermediate risk of pancreatitis. A study to investigate the efficacy of this recommendation was performed...
April 18, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29665121/homoharringtonine-could-induce-quick-protein-synthesis-of-psmd11-through-activating-mek1-erk1-2-signaling-pathway-in-pancreatic-cancer-cells
#12
Lele Wang, Linlin Zhao, Guo Wei, Dieter Saur, Barbara Seidler, Junyan Wang, Chuanxin Wang, Tonggang Qi
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most devastating disease with the 5-year survival rate less than 6%. In this study, we investigated if inhibiting protein synthesis directly with homoharringtonine (HHT) could induce acute apoptosis in pancreatic cancer cells through quick depletion of multiple short-lived critical members of the central proteome, example, PSMD11(26S proteasome non-ATPase regulatory subunit 11). It was shown that although HHT could inhibit proliferation and growth of MiaPaCa-2 and PANC-1 cells in a time- and dose-dependent manner, only part of pancreatic cancer cells could be induced to die through acute apoptosis...
April 17, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29663140/poorly-differentiated-ductal-adenocarcinoma-of-the-pancreas-with-rapid-progression-in-a-young-man
#13
Koji Tezuka, Tomoharu Ishiyama, Akiko Takeshita, Hidekazu Matsumoto, Akira Jingu, Jiro Kikuchi, Hideyuki Yamaya, Rintaro Ohe, Tetsuya Ishizawa
Pancreatic cancer in young adults is very rare. We report a case of young-onset poorly differentiated pancreatic ductal adenocarcinoma with rapid progression and poor prognosis in a 31-year-old Japanese man with no obvious family history of malignancy. Preoperative examinations revealed a mass lesion in the body of the pancreas, accompanied by a slightly dilated main pancreatic duct distal to the mass lesion. Pancreatic cancer with acute pancreatitis was suspected because of an elevation of serum pancreatic enzyme and tumor marker, along with imaging findings...
April 16, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29663019/-retrieval-of-a-migrated-plastic-stent-in-a-51-year-old-man
#14
A Poszler, P Klare, A Weber, M Abdelhafez, K Holzapfel, R M Schmid, S von Delius
BACKGROUND: Endosonographically guided transgastric drainage is the first-line interventional therapy of walled-off necrosis and symptomatic pancreatic pseudocysts in necrotizing pancreatitis. Plastic stents or lumen apposing metal stents are commonly used. A possible complication of endoscopic therapy is stent migration. CASE REPORT: We report upon a 51-year-old man who presented with acute necrotizing pancreatitis. Transgastric necrosectomy was performed and 5 transmural double-pigtail stents (DPS) were left in situ to drain the residual retroperitoneal cavity...
April 16, 2018: Der Internist
https://www.readbyqxmd.com/read/29662703/aortic-dissection-presenting-as-acute-pancreatitis-suspecting-the-unexpected
#15
Adam Hafeez, Dillon Karmo, Adrian Mercado-Alamo, Alexandra Halalau
Aortic dissection is a life-threatening condition in which the inner layer of the aorta tears. Blood surges through the tear, causing the inner and middle layers of the aorta to separate (dissect). It is considered a medical emergency. We report a case of a healthy 56-year-old male who presented to the emergency room with sudden onset of epigastric pain radiating to his back. His blood pressure was 167/91 mmHg, equal in both arms. His lipase was elevated at 1258 U/L, and he was clinically diagnosed with acute pancreatitis (AP)...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29662656/stereotactic-body-radiation-therapy-for-palliative-management-of-pancreatic-adenocarcinoma-in-elderly-and-medically-inoperable-patients
#16
John F Ryan, Lauren M Rosati, Vincent P Groot, Dung T Le, Lei Zheng, Daniel A Laheru, Eun J Shin, Juan Jackson, Joseph Moore, Amol K Narang, Joseph M Herman
Stereotactic body radiation therapy (SBRT) represents a promising treatment option for patients with localized pancreatic ductal adenocarcinoma (PDAC) who cannot tolerate surgical therapy. We retrospectively reviewed the records of patients with localized PDAC treated with SBRT at our institution between 2010 and 2016 to identify patients deemed medically inoperable due to poor performance status, advanced age, and/or comorbid conditions. Overall survival (OS), progression-free survival (PFS), and local progression-free survival (LPFS) were estimated using Kaplan-Meier curves...
March 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29662328/hyporeninemic-hypoaldosteronism-in-a-patient-with-diabetes-mellitus-an-unforgettable-case-report
#17
Naziha Chelaghma, Samson O Oyibo
A 58-year-old man presented with a 3-year history of chronic and intermittent hyperkalemia requiring recurrent attendances to the emergency department for urgent treatment. His medical history included secondary diabetes mellitus following a bout of acute pancreatitis and a previous splenectomy for a spontaneous splenic rupture. He also had a history of prolonged use of non-steroidal anti-inflammatory drugs for back pain and painful neuropathy. He was not on any medication or diet that would cause a raised serum potassium level and his renal function was normal...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29660323/nationwide-trends-in-acute-and-chronic-pancreatitis-among-privately-insured-children-and-non-elderly-adults-in-the-united-states-2007-2014
#18
Zachary M Sellers, Donna MacIsaac, Helen Yu, Melody Dehghan, Ke-You Zhang, Rachel Bensen, Jessie J Wong, Cindy Kin, K T Park
BACKGROUND & AIMS: Epidemiologic analyses of acute and chronic pancreatitis (AP and CP) provide insight into causes and strategies for prevention, and affect allocation of resources to its study and treatment. We sought to determine current and accurate incidences of AP and CP, along with the prevalence of CP, in children and adults in the United States. METHODS: We collected data from the Truven MarketScan Research Databases of commercial inpatient and outpatient insurance claims in the United States from 2007 through 2014 (patients 0-64 years old)...
April 13, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29659879/orlistat-therapy-for-children-with-type-1-hyperlipoproteinemia-a-randomized-clinical-trial
#19
Nivedita Patni, Claudia Quittner, Abhimanyu Garg
Context: Patients with Type I Hyperlipoproteinemia (T1HLP), a rare genetic disorder, present with significant chylomicronemia and recurrent episodes of acute pancreatitis. Currently, the only therapeutic option is to consume an extremely low fat diet, as the triglyceride lowering medications are not efficacious. Objective: To determine the efficacy of Orlistat, a gastric and pancreatic lipase inhibitor, Orlistat, in reducing serum triglyceride levels in patients with T1HLP...
April 5, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29659085/gastrointestinal-recurrent-acute-pancreatitis-with-a-large-fluid-collection-pseudocyst-or-else
#20
Z Nabi, J R Singh, D Nageshwar Reddy
No abstract text is available yet for this article.
May 2018: Journal of Gastroenterology and Hepatology
keyword
keyword
1115
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"