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https://www.readbyqxmd.com/read/29166709/-effects-of-dexmedetomidine-on-myocardium-of-rats-with-severe-burn-at-early-stage
#1
D Wang, P L Yang, X Zhang, Y Liu
Objective: To investigate the effects of dexmedetomidine on myocardium of rats at early stage after severe burn. Methods: Twenty specific pathogen free male SD rats were immersed in 90 ℃ hot water for 20 s, causing 30% total body surface area (TBSA) full-thickness scald (hereafter referred to as burn) on the back. And then they were divided into burn resuscitation group (BR) and burn resuscitation+ dexmedetomidine group (BRD) according to the random number table, with 10 rats in each group. Sodium lactate Ringer's solution (2 mL·kg(-1)·%TBSA(-1)) were intraperitoneally injected into rats of both groups after burn...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166375/gastric-emptying-of-different-meal-volumes-of-identical-composition-in-preterm-infants-a-time-series-analysis
#2
Sharon L Perrella, Anna R Hepworth, Zoya Gridneva, Karen N Simmer, Peter E Hartmann, Donna T Geddes
BACKGROUND: Preterm infants' meals typically progress to higher volumes over time. Knowledge of gastric emptying (GE) responses to differing meal volumes may inform enteral feeding management. We examined the effect of meal volume and composition on preterm GE. METHODS: Forty infants were studied at 33.3±1.4 (29.7-35.6) weeks postmenstrual age when fully enteral fed (target 150 ml/kg/day). Intra-individual comparisons of GE were made for paired meals of 100 and 75% prescribed volume and identical composition of mother's own milk (n=21) and pasteurized donor human milk (n=19)...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29165881/nerve-injury-associated-with-high-intensity-focused-ultrasound-a-case-report
#3
Angkana Sathaworawong, Rungsima Wanitphakdeedecha
Skin laxity is a common cosmetic concern in middle-aged women. High-intensity focused ultrasound (HIFU) is one of noninvasive modalities that provides safe and effective improvement in skin laxity and tightening with minimal adverse effects. Concerning an extensive use of HIFU for facial rejuvenation, dermatologists should be aware of potential adverse effects of HIFU treatment. We herein present a case of 33-year-old Thai female with facial nerve injury after HIFU treatment for skin laxity.
November 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29165501/a-study-of-the-effectiveness-and-energy-efficiency-of-ultrasonic-emulsification
#4
Wu Li, Thomas S H Leong, Muthupandian Ashokkumar, Gregory J O Martin
Three essential experimental parameters in the ultrasonic emulsification process, namely sonication time, acoustic amplitude and processing volume, were individually investigated, theoretically and experimentally, and correlated to the emulsion droplet sizes produced. The results showed that with a decrease in droplet size, two kinetic regions can be separately correlated prior to reaching a steady state droplet size: a fast size reduction region and a steady state transition region. In the fast size reduction region, the power input and sonication time could be correlated to the volume-mean diameter by a power-law relationship, with separate power-law indices of -1...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29165099/recent-patents-and-formulation-of-nanopharmaceuticals-using-ultrasonication-technique
#5
Nidhi Saiwal, Mandeep Dahiya, Harish Dureja
BACKGROUND: Ultrasound (US) has the ever-rising role in the delivery of therapeutic agents that includes chemotherapeutic agents, proteins, and genetic material. The microbubbles are the cavitating gas bodies that act as the mediators through which the energy of relatively non-interactive pressure waves is accumulated to produce forces that can permeabilize cell membranes and disrupt the vesicles that carry the therapeutic agent. This shows that the microbubbles greatly enhance the delivery of smaller chemical agents, proteins and genetic material...
November 19, 2017: Recent Patents on Nanotechnology
https://www.readbyqxmd.com/read/29164530/ultrasound-guided-lateral-medial-transmuscular-quadratus-lumborum-block-for-analgesia-following-anterior-iliac-crest-bone-graft-harvesting-a-clinical-and-anatomical-study
#6
Rakesh V Sondekoppam, Vivian Ip, David F Johnston, Vishal Uppal, Marjorie Johnson, Sugantha Ganapathy, Ban C H Tsui
BACKGROUND: The anterior iliac crest (AIC) is one of the most common sites for harvesting autologous bone, but the associated postoperative pain can result in significant morbidity. Recently, the transmuscular quadratus lumborum block (TQL) has been described to anesthetize the thoraco-lumbar nerves. This study utilizes a combination of cadaveric models and clinical case studies to evaluate the dermatomal coverage and analgesic utility of TQL for AIC bone graft donor site analgesia. METHODS: Ten ultrasound-guided TQL injections were performed in five cadaver specimens using a lateral-to-medial transmuscular approach...
November 21, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29164399/efficacy-of-a-single-intra-articular-injection-of-ultra-high-molecular-weight-hyaluronic-acid-for-hip-osteoarthritis-a-randomized-controlled-study
#7
Daniele Clementi, Riccardo D'Ambrosi, Paride Bertocco, Miguel Simon Bucci, Carlo Cardile, Paolo Ragni, Graziella Giaffreda, Vincenza Ragone
BACKGROUND: Viscosupplementation with hyaluronic acid (HA) is increasingly used for the treatment of hip osteoarthritis (OA). The purpose of this study was to compare the efficacy of intra-articular injections of an ultra-high molecular weight viscosupplement (UHMW-HA, Fermathron S) with a medium molecular weight hyaluronan (MMW-HA, Hyalubrix 60) in hip OA. METHODS: Fifty-four patients with hip OA grade 3 on the Kellgren/Lawrence scale were randomized. All infiltrations were performed under ultrasound guidance...
November 21, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29163988/effect-of-mt3-on-retinal-and-choroidal-tgf-%C3%AE-2-and-has2-expressions-in-form-deprivation-myopia-of-guinea-pig
#8
Tao Li, Xiaodong Zhou, Bing Li, Bo Jiang
Purpose: To confirm its dose-dependent effect on form deprivation myopia and evaluate the effect of MT3 at different tissue concentrations on changes in mRNA and protein expression for TGF-β2 and HAS2. Methods: MT3 was intravitreally injected into deprived eyes at two-day intervals. Refraction was measured by streak retinoscopy after cycloplegia. The axial dimensions were measured by A-scan ultrasound. The quantitative RT-PCR and Western blot were used to detect the changes of TGF-β2 and HAS2 expressions in the retina and choroid of guinea pigs...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29163662/a-case-report-of-lung-ultrasound-missing-a-pneumothorax-due-to-patient-positioning
#9
David Schrift, Keith Barron, Michael Wagner, Rohan Arya
Lung ultrasound is increasingly utilized as a diagnostic tool for the detection of a pneumothorax. The effect of small changes in patient positioning on the accuracy of lung ultrasound to detect a pneumothorax is not well studied. We present the first known case of lung ultrasound missing a pneumothorax because of suboptimal patient positioning, and discuss the implications of our findings for clinicians that utilize lung ultrasound and for future research.
November 2017: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29163193/changes-in-muscle-and-cerebral-deoxygenation-and-perfusion-during-repeated-sprints-in-hypoxia-to-exhaustion
#10
Sarah J Willis, Laurent Alvarez, Grégoire P Millet, Fabio Borrani
During supramaximal exercise, exacerbated at exhaustion and in hypoxia, the circulatory system is challenged to facilitate oxygen delivery to working tissues through cerebral autoregulation which influences fatigue development and muscle performance. The aim of the study was to evaluate the effects of different levels of normobaric hypoxia on the changes in peripheral and cerebral oxygenation and performance during repeated sprints to exhaustion. Eleven recreationally active participants (six men and five women; 26...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29162245/ultrasound-guided-supra-acetabular-pin-placement-in-pelvic-external-fixation-description-of-a-surgical-technique-and-results
#11
Francisco Chana-Rodríguez, Manuel Cuervas-Mons, José Rojo-Manaute, Félix Mora, Juan Arnal, Javier Vaquero-Martín
INTRODUCTION: Pelvic fracture in trauma patients can lead to hemodynamic instability. External fixation is a treatment capable of stabilizing these injuries in the context of damage control surgery. Supra-acetabular pin offers the greater biomechanical stability but requires the use of intraoperative fluoroscopy. The aim of this study was to analyze our results for an ultrasound-guided supra-acetabular pinning. MATERIAL AND METHODS: Cross-sectional study with cadaveric specimens...
November 2017: Injury
https://www.readbyqxmd.com/read/29162156/the-use-of-5-fluorouracil-loaded-nanobubbles-combined-with-low-frequency-ultrasound-to-treat-hepatocellular-carcinoma-in-nude-mice
#12
Qiaoya Li, Hongyang Li, Chengjun He, Zhouhong Jing, Changan Liu, Juan Xie, Wenwen Ma, Huisheng Deng
OBJECTIVE: This study aimed to investigate the therapeutic effects of 5-fluorouracil (5-FU)-loaded nanobubbles irradiated with low-intensity, low-frequency ultrasound in nude mice with hepatocellular carcinoma (HCC). METHODS: A transplanted tumor model of HCC in nude mice was established in 40 mice, which were then randomly divided equally into four groups: group A (saline), group B (5-FU-loaded nanobubbles), group C (5-FU-loaded nanobubbles with non-low-frequency ultrasound), and group D (5-FU-loaded nanobubbles with low-frequency ultrasound)...
November 21, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29161924/ultrasound-guided-percutaneous-microwave-ablation-vs-surgical-resection-for-thoracoabdominal-wall-implants-from-hepatocellular-carcinoma-intermediate-term-results
#13
Chao An, Zi-Long Hu, Ping Liang, Zhi-Gang Cheng, Zhi-Yu Han, Jie Yu, Fang-Yi Liu
OBJECTIVE: The aims of this study were to compare the clinical outcomes between ultrasound (US)-guided percutaneous microwave ablation (MWA) and surgical resection (SR) in patients with thoracoabdominal wall implants from hepatocellular carcinom (HCC) and to identify the prognostic factors associated with the two treatment methods. MATERIALS AND METHODS: A total of 47 patients (mean age, 56.7 ± 15.9 years, range, 18-78 years; 34 men and 13 women) with 61 thoracoabdominal wall HCC seeding were included from April 2007 to May 2017...
November 21, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29161769/influence-of-biceps-brachii-tendon-mechanical-properties-on-elbow-flexor-force-steadiness-in-young-and-old-males
#14
Rowan R Smart, Stéphane Baudry, Andrey Fedorov, Samantha L Kuzyk, Jennifer M Jakobi
Elbow flexor force steadiness (FS) depends on strength and decreases with age. Achilles tendon mechanics effect standing balance and isometric plantarflexion FS. This study investigated the influence of distal biceps brachii (BB) tendon mechanics and elbow flexor strength on age-related decline in FS. Nine young (23±2 years) and 9 old (77±5 years) males performed submaximal isometric elbow flexion tasks at low (2.5, 5, 10% maximal voluntary contraction (MVC)) and high (20, 40, 60, 80%MVC) forces in a neutral forearm position...
November 21, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29161715/management-of-biochemical-recurrence-after-primary-curative-treatment-for-prostate-cancer-a-review
#15
Walter Artibani, Antonio Benito Porcaro, Vincenzo De Marco, Maria A Cerruto, Salvatore Siracusano
How to manage patients with prostate cancer (PCa) with biochemical recurrence (BCR) following primary curative treatment is a controversial issue. Importantly, this prostate-specific antigen (PSA)-only recurrence is a surrogate neither of PCa-specific survival nor of overall survival. Physicians are therefore challenged with preventing or delaying the onset of clinical progression in those deemed at risk, while avoiding over-treating patients whose disease may never progress beyond PSA-only recurrence. Adjuvant therapy for radical prostatectomy (RP) or local radiotherapy (RT) has a role in certain at-risk patients, although it is not recommended in low-risk PCa owing to the significant side-effects associated with RT and androgen deprivation therapy (ADT)...
November 21, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29161695/a-randomized-controlled-trial-of-comparing-ultrasound-guided-transversus-abdominis-plane-block-with-local-anesthetic-infiltration-in-peritoneal-dialysis-catheter-implantation
#16
Qi Li, Xiaohong Tang, Tian Tao, Wenjuan Zhang, Wei Qin, Jie Zhang, Zi Li
BACKGROUND: The ultrasound-guided transversus abdominis plane (TAP) block has been demonstrated as a useful analgesia technique in lower-abdomen surgeries. We hypothesized that it could be the principal anesthesia technique for end-stage renal disease (ESRD) patients undergoing peritoneal dialysis (PD) catheter (PDC) implantation using the open dissection method. METHODS: This was a single-center, prospective, randomized, and double-blinded study. All eligible patients were randomized into 2 groups: the TAP block group (n = 20) and the local anesthetic infiltration (LAI) group (n = 20)...
November 22, 2017: Blood Purification
https://www.readbyqxmd.com/read/29161293/high-intensity-focused-ultrasound-ablation-around-the-tubing
#17
Jun Yang Siu, Chenhui Liu, Yufeng Zhou
High-intensity focused ultrasound (HIFU) has been emerging as an effective and noninvasive modality in cancer treatment with very promising clinical results. However, a small vessel in the focal region could be ruptured, which is an important concern for the safety of HIFU ablation. In this study, lesion formation in the polyacrylamide gel phantom embedded with different tubing (inner diameters of 0.76 mm and 3 mm) at varied flow speeds (17-339 cm/s) by HIFU ablation was photographically recorded. Produced lesions have decreased length (~30%) but slightly increased width (~6%) in comparison to that without the embedded tubing...
2017: PloS One
https://www.readbyqxmd.com/read/29160551/effects-of-pilates-and-yoga-in-patients-with-chronic-neck-pain-a-sonographic-study
#18
Naime Uluğ, Öznur Tunca Yılmaz, Murat Kara, Levent Özçakar
BACKGROUND: Various studies have shown the efficacy of conventional isometric, Pilates and yoga exercises. However, data on the effects and comparison of these specific exercises on the cervical muscle morphology are insufficient or lacking. OBJECTIVE: To investigate the effects of different exercise treatments on neck muscles in patients with chronic neck pain. DESIGN: A randomized study. METHODS: Fifty-six patients with chronic neck pain were randomized into 3 groups as follows: Pilates group (n = 20), yoga group (n = 18) and isometric group (n = 18)...
November 16, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29160427/review-of-magnetic-resonance-guided-focused-ultrasound-in-the-treatment-of-uterine-fibroids
#19
Pedro Felipe Magalhães Peregrino, Marcos de Lorenzo Messina, Ricardo Dos Santos Simões, José Maria Soares-Júnior, Edmund Chada Baracat
Uterine leiomyoma is the most frequently occurring solid pelvic tumor in women during the reproductive period. Magnetic resonance-guided high-intensity focused ultrasound is a promising technique for decreasing menorrhagia and dysmenorrhea in symptomatic women. The aim of this study is to review the role of Magnetic resonance-guided high-intensity focused ultrasound in the treatment of uterine fibroids in symptomatic patients. We performed a review of the MEDLINE and Cochrane databases up to April 2016. The analysis and data collection were performed using the following keywords: Leiomyoma, High-Intensity Focused Ultrasound Ablation, Ultrasonography, Magnetic Resonance Imaging, Menorrhagia...
October 2017: Clinics
https://www.readbyqxmd.com/read/29160060/phase-transition-nanoparticles-as-multimodality-contrast-agents-for-the-detection-of-thrombi-and-targeting-thrombolysis-in-vitro-and-in-vivo-experiments
#20
Jie Xu, Jun Zhou, Yixin Zhong, Yu Zhang, Jia Liu, Yuli Chen, Liming Deng, Danli Sheng, Zhigang Wang, Haitao Ran, Dajing Guo
Thrombotic disease is extremely harmful to human health, and early detection and treatment can improve the prognosis and reduce mortality. Multimodal molecular imaging can provide abundant information about thrombi, but to date, few studies have used multimodal and multifunctional nanoparticles (NPs) for thrombus detection and targeting thrombolysis. In this study, phase transition multimodal and multifunctional NPs (EWVDV-Fe-Ink-PFH NPs) were constructed for the first time using a three-step emulsification and carbodiimide method, and the physical and chemical properties of the NPs were investigated...
November 21, 2017: ACS Applied Materials & Interfaces
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