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https://www.readbyqxmd.com/read/28944865/middle-pregnancy-ultrasound-screening-for-fetal-chromosomal-diseases
#1
Li Liu, Ping Zhou, Zemin Cao, Xiaojun Tan
Prenatal examinations, including serological screening and ultrasound screening, are the methods determining a risk of fetal chromosomal disease. The current study is aimed to assess whether ultrasound screening can effectively assist the screening for fetal chromosomal disease among pregnant women with a single abnormal serum marker. Following serologic screening, pregnant women at 18‑32 weeks underwent systematic fetal ultrasound analysis. In this study, 99 pregnant women with an abnormal serum marker and fetal ultrasound abnormalities underwent prenatal diagnosis of amniotic fluid or umbilical cord blood, with confirmation by pathological examination performed following birth or induced labor...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944824/efficient-gene-therapy-with-a-combination-of-ultrasound%C3%A2-targeted-microbubble-destruction-and-pei-dna-nls-complexes
#2
Yi-Jia Wang, Qing Zhou, Sheng Cao, Bo Hu, Qing Deng, Nan Jiang, Jingjing Cui
Current strategies of gene transfection are not efficient at achieving a notable therapeutic effect. The aim of the present study was to combine ultrasound‑targeted microbubble destruction (UTMD) with a polyethylenimine/pEGFP‑N3 plasmid/nuclear localization sequence (PEI/DNA/NLS) complex gene delivery system, and evaluate the transfection efficiency of enhanced green fluorescent protein (EGFP) gene delivery to 293T cells using this system. The formation of PEI/DNA/NLS complexes and the protective effects of PEI/NLS were verified by gel electrophoresis...
September 18, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944490/hybrid-ultrasound-mr-guided-hifu-treatment-method-with-3d-motion-compensation
#3
Zarko Celicanin, Gibran Manasseh, Lorena Petrusca, Klaus Scheffler, Vincent Auboiroux, Lindsey A Crowe, Jean-Noel Hyacinthe, Yutaka Natsuaki, Francesco Santini, Christoph D Becker, Sylvain Terraz, Oliver Bieri, Rares Salomir
PURPOSE: Treatments using high-intensity focused ultrasound (HIFU) in the abdominal region remain challenging as a result of respiratory organ motion. A novel method is described here to achieve 3D motion-compensated ultrasound (US) MR-guided HIFU therapy using simultaneous ultrasound and MRI. METHODS: A truly hybrid US-MR-guided HIFU method was used to plan and control the treatment. Two-dimensional ultrasound was used in real time to enable tracking of the motion in the coronal plane, whereas an MR pencil-beam navigator was used to detect anterior-posterior motion...
September 24, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28944192/intraocular-pressure-control-of-a-novel-glaucoma-drainage-device-in-vitro-and-in-vivo-studies
#4
Li-Jun Cui, Di-Chen Li, Jian Liu, Lei Zhang, Yao Xing
AIM: To evaluate the intraocular pressure (IOP) control of an artificial trabeculum drainage system (ATDS), a newly designed glaucoma drainage device, and postoperative complications in normal rabbit eyes. METHODS: Pressure drops in air and fluid of 30 ATDS were measured after being connected to a closed manometric system. Twenty of them were then chosen and implanted randomly into the eyes of 20 rabbits. Postoperative slit-lamp, gonioscopic examination and IOP measurements were recorded periodically...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28943307/the-role-of-ultrasound-technology-in-plastic-surgery
#5
REVIEW
Tyler Safran, Kevin Gorsky, Alex Viezel-Mathieu, Jonathan Kanevsky, Mirko S Gilardino
INTRODUCTION: The modern medical era is in part characterized by the increased availability of portable imaging devices. Ultrasound devices are used for either high-resolution non-invasive imaging or as a focused acoustic energy source capable of sculpting and shaping tissue. Given the broad scope of the field, plastic and reconstructive surgeons have the unique ability to implement and tailor the use of ultrasound in a variety of clinical situations. This article will review novel uses for ultrasound in the field of plastic surgery...
September 13, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28943161/ultrasound-guided-versus-landmark-guided-local-corticosteroid-injection-for-carpal-tunnel-syndrome-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#6
REVIEW
Arash Babaei-Ghazani, Peyman Roomizadeh, Bijan Forogh, Seyed-Mohammad Moeini-Taba, Amin Abedini, Mona Kadkhodaie, Fateme Jahanjoo, Bina Eftekharsadat
OBJECTIVE: To review the literature and assess the comparative effectiveness of ultrasound-guided versus landmark-guided local corticosteroid injections in patients with carpal tunnel syndrome (CTS). DATA SOURCES: Cochrane Central Register of Controlled Trials, MEDLINE (PubMed), EMBASE (Ovid), and Web of Science (from inception to 1 February 2017). STUDY SELECTION: Randomized controlled trials (RCTs) comparing ultrasound-guided injection to landmark-guided injection in patients with CTS were included...
September 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28943075/a-novel-absorbable-radiopaque-hydrogel-spacer-to-separate-the-head-of-the-pancreas-and-duodenum-in-radiation-therapy-for-pancreatic-cancer
#7
Avani D Rao, Ziwei Feng, Eun Ji Shin, Jin He, Kevin M Waters, Stephanie Coquia, Robert DeJong, Lauren M Rosati, Lin Su, Dengwang Li, Juan Jackson, Stephen Clark, Jeffrey Schultz, Danielle Hutchings, Seong-Hun Kim, Ralph H Hruban, Theodore L DeWeese, John Wong, Amol Narang, Joseph M Herman, Kai Ding
PURPOSE: We assessed the feasibility and theoretical dosimetric advantages of an injectable hydrogel to increase the space between the head of the pancreas (HOP) and duodenum in a human cadaveric model. METHODS AND MATERIALS: Using 3 human cadaveric specimens, an absorbable radiopaque hydrogel was injected between the HOP and duodenum by way of open laparotomy in 1 case and endoscopic ultrasound (EUS) guidance in 2 cases. The cadavers were subsequently imaged using computed tomography and dissected for histologic confirmation of hydrogel placement...
August 14, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28943040/treatment-of-musculo-skeletal-pain-in-haemophilia
#8
REVIEW
E Carlos Rodriguez-Merchan
Musculo-skeletal pain treatment is inadequate in many haemophilic patients. Analgesics are used only by 36% of adult patients. FVIII/FIX intravenous infusion is mainly used to lessen pain, followed in frequency by usage of NSAIDS (primarily COX-2 inhibitors). In about 30% of patients, pain continues after infusion of F VIII/IX. In acute haemarthroses pain treatment must continue until total disappearance (checked by ultrasonography) and include haematologic treatment, short-term rest of the involved joint, cryotherapy, joint aspiration and analgesic medication (paracetamol in mild pain, metamizole for more intense pain, and in a few precise patients, soft opioids such as codeine or tramadol)...
September 19, 2017: Blood Reviews
https://www.readbyqxmd.com/read/28942695/ovarian-stimulation-under-the-effect-of-isotretinoin
#9
Mauro Cozzolino, Javier Domingo, Sérgio Reis Soares
Isotretinoin (13-cis-retinoic acid) is a pharmaceutical vitamin A analog that is frequently used in the treatment of severe cystic acne, many women at reproductive age being exposed to this substance. This drug has a clearly documented teratogenicity and data from rodents and humans indicate that a direct aggression to ovarian follicles also occurs. Here we report the case of a 29-year-old woman with breast cancer referred for emergency preservation of reproductive potential that used isotretinoin up to the day before the initiation of ovarian stimulation...
September 23, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28942682/near-infrared-light-mediated-photochemotherapy-for-efficiently-treating-deep-orthotopic-tumors-guided-by-ultrasound-imaging
#10
Zuhua Wang, Shaoyan Xuan, Wenqi Qiu, Jiang Zhu, Xiaomeng Guo, Wei Li, Hanbo Zhang, Xiuliang Zhu, Yong-Zhong Du, Jian You
Recently, Combined cancer photothermal-chemotherapy has become a highly promising strategy in cancer treatment for its enhanced therapeutic efficacy, controlled drug release and reduced systemic toxicity. Almost all the reported strategies based on photothermal-chemotherapy have only focused on the treatment of superficial or subcutaneous cancer, which are not considered as a more clinically relevant and better predictive models of drug efficacy than orthotopic tumor models. Here, we reported an EphB4 receptor-targeting polymeric nanoplatform containing hollow gold nanospheres (HAuNS) and the anticancer drug paclitaxel (PTX) for cancer photothermal-chemotherapy...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28942661/-etanercept-induced-subacute-thyroiditis-case-report-and-literature-review
#11
Zoltán Hella, László Hodinka, Piroska Turbucz, Gábor László Kovács
65 years old male patient received 4 mg/day methylprednisolone baseline therapy and 50 mg/week etanercept treatment for 5 years due to rheumatoid arthritis. The patient experienced pain in neck, and developed weakness, fever and dysphagia. He had normal blood count but accelerated erythrocyte sedimentation rate (88 mm/hour), elevated CRP (49.3 mg/l) and hyperthyroidism (TSH 0.006 mIU/l, fT4 27.22 pmol/l, fT3 5.61 pmol/l). The autoimmune origin could be excluded because of normal values of antibodies against thyreoidea peroxidase and TSH receptor...
October 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28942271/microstructure-changes-in-ultrafine-grained-nickel-processed-by-high-pressure-torsion-under-ultrasonic-treatment
#12
A A Samigullina, A A Mukhametgalina, S N Sergeyev, A P Zhilyaev, A A Nazarov, Yu R Zagidullina, N Yu Parkhimovich, V V Rubanik, Yu V Tsarenko
Commercially pure nickel was processed by high pressure torsion (HPT) and subjected to ultrasonic treatment (UST) with different amplitudes of compression-tension stresses in the zone of stress antinode of a standing wave. It was found that microstructure parameters such as the dislocation density, low- and high-angle grain boundary fractions, microhardness, and the stored excess energy as well, non-monotonically depend on the ultrasound amplitude. A structure relaxation leading to a reduction of internal stresses and stored energy and increase of the fraction of high-angle boundaries was observed at some intermediate amplitudes of the oscillating stress...
September 15, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28942118/carpal-tunnel-syndrome-effectiveness-of-physical-therapy-and-electrophysical-modalities-an-updated-systematic-review-of-randomized-controlled-trials
#13
REVIEW
Bionka M A Huisstede, Peter Hoogvliet, Thierry P C Franke, Manon S Randsdorp, Bart W Koes
OBJECTIVE: To review scientific literature studying the effectiveness of physical therapy and electrophysical modalities for carpal tunnel syndrome (CTS). DATA SOURCES: The Cochrane Library, PubMed, EMBASE, CINAHL, and PEDro. STUDY SELECTION: Two reviewers independently applied the inclusion criteria to select potential eligible studies. DATA EXTRACTION: Two reviewers independently extracted the data and assessed the methodological quality using the Cochrane Risk of Bias Tool...
September 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28941973/left-handed-skeletally-mature-baseball-players-have-smaller-humeral-retroversion-in-the-throwing-arm-than-right-handed-players
#14
Tetsuya Takenaga, Hideyuki Goto, Katsumasa Sugimoto, Atsushi Tsuchiya, Masaki Fukuyoshi, Hiroki Nakagawa, Masahiro Nozaki, Satoshi Takeuchi, Takanobu Otsuka
BACKGROUND: It is known that the humeral retroversion of baseball players is greater in the throwing arm than in the nonthrowing arm. An investigation measuring dry bone specimens also showed that the right humerus had greater retroversion than the left. Considering these facts, it was hypothesized that humeral retroversion would differ between right- and left-handed players. This study aimed to compare the bilateral humeral retroversion between right- and left-handed skeletally mature baseball players...
September 20, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28941918/impact-of-lesion-visibility-on-transrectal-ultrasound-on-the-prediction-of-clinically-significant-prostate-cancer-gleason-score-%C3%A2-3-4-with-trus-mri-fusion-biopsy
#15
Kirema Garcia-Reyes, Hao G Nguyen, Ronald J Zagoria, Katsuto Shinohara, Peter R Carroll, Spencer C Behr, Antonio C Westphalen
PURPOSE: The purpose of this study was to estimate the impact of lesion visibility with TRUS on the prediction of CS-PCA with TRUS-MRI fusion biopsy. MATERIALS AND METHODS: This HIPAA-compliant, IRB-approved retrospective study included 178 men (age, 64.7 years; PSA, 8.9 ng/ml) who underwent TRUS-MRI fusion biopsy from January/2013 to September/2016. Visible lesions on MRI were those assigned a PI-RADS v2 score ≥ 3. TRUS was positive when a hypoechoic lesion was identified...
September 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28941396/real-time-ultrasound-angiography-using-superharmonic-dual-frequency-2-25mhz-30mhz-cylindrical-array-in-vitro-study
#16
Zhuochen Wang, K Heath Martin, Paul A Dayton, Xiaoning Jiang
Recent studies suggest that dual-frequency intravascular ultrasound (IVUS) transducers allow detection of superharmonic bubble signatures, enabling acoustic angiography for microvascular and molecular imaging. In this paper, a dual-frequency IVUS cylindrical array transducer was developed for real-time superharmonic imaging. A reduced form-factor lateral mode transmitter (2.25MHz) was used to excite microbubbles effectively at 782kPa with single-cycle excitation while still maintaining the small size and low profile (5Fr) (3Fr=1mm) for intravascular imaging applications...
September 15, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28940899/low-intensity-pulsed-ultrasound-activates-erk1-2-and-pi3k-akt-signalling-pathways-and-promotes-the-proliferation-of-human-amnion-derived-mesenchymal-stem-cells
#17
Li Ling, Tianqin Wei, Lianli He, Yaping Wang, Yan Wang, Xiushan Feng, Wenqian Zhang, Zhengai Xiong
OBJECTIVES: This study was to investigate the effect and mechanism of low-intensity pulsed ultrasound (LIPUS) on the proliferation of human amnion-derived mesenchymal stem cells (hAD-MSCs). METHODS: Human amnion-derived mesenchymal stem cells were isolated from the amnion of term placentas and identified by flow cytometry and differentiation culture. Proliferation of hAD-MSCs was investigated by Cell Counting Kit-8, cell cycle and EdU assays. Western blotting was used to determine the protein expression levels...
September 22, 2017: Cell Proliferation
https://www.readbyqxmd.com/read/28940658/community-based-screening-to-detect-school-readiness-problems-in-very-preterm-children
#18
Nitin Rajput, Chris McKinlay, Gordon Purdie, Julia Filipovska, Malcolm Battin, Harshad Patel, Pat Tuohy
AIM: Very preterm (VPT) children (≤32 weeks) have school readiness difficulties across multiple domains, but routine follow-up is often limited. We assessed the performance of VPT children on the Before School Check (B4SC), a community-based screening programme of school readiness at 4 years of age. METHODS: VPT children discharged from Wellington and Auckland Neonatal Intensive Care Units (2005-2009) were compared to a national control cohort born during the same period...
September 20, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28940638/does-l-citrulline-supplementation-improve-exercise-blood-flow-in-older-adults
#19
Joaquin U Gonzales, Andrea Raymond, John Ashley, Youngdeok Kim
L-citrulline (Cit) increases arginine (Arg), the primary substrate for nitric oxide biosynthesis. We tested the hypothesis that muscle blood flow during exercise would be enhanced by Cit supplementation in older adults. Femoral artery blood flow was measured during calf exercise using Doppler ultrasound, and vascular conductance (FVC) was calculated in 25 older adults (13W, 12M) before and after 14 days of Cit (6 g day(-1) ) and placebo (maltodextrin) in a randomized, double-blind, crossover study. Plasma [Arg] and resting blood pressure were also measured before and after each condition...
September 20, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28940451/effect-of-the-novel-selective-progesterone-receptor-modulator-vilaprisan-on-ovarian-activity-in-healthy-women
#20
Barbara Schütt, Marcus-Hillert Schultze-Mosgau, Corinna Draeger, Xinying Chang, Stephanie Löwen, Andreas Kaiser, Beate Rohde
This randomized, double-blind, parallel-group study in healthy young women investigated the effect of treatment with vilaprisan (0.5, 1, 2, or 4 mg/day for 12 weeks) on ovarian function by assessing the Hoogland score, which is based on the size of follicle-like structures as determined by transvaginal ultrasound and on estradiol and progesterone serum concentrations. Ovulation inhibition (ie, Hoogland score <6 in treatment weeks 1-4 and 8-12) was observed in >80% of the subjects receiving vilaprisan ≥1 mg/day...
September 21, 2017: Journal of Clinical Pharmacology
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