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liposarcoma testicular

Subramaniyan Ramanathan, Vineetha Raghu, Devendra Kumar, Venkata R P Sempiege
Sclerosing liposarcoma of epididymis is a rare extratesticular scrotal tumor with variable prognosis. Ultrasonography is the initial imaging modality of choice for the evaluation of scrotal mass and helps to differentiate testicular and extratesticular masses, thereby narrowing down the differential diagnosis. Magnetic resonance imaging with its excellent soft tissue resolution can help in the further characterization of the nature of the tumor. In this case report, we highlight the role of chemical shift imaging in making a confident preoperative diagnosis of liposarcoma thereby guiding optimal and timely management...
July 2016: Indian Journal of Radiology & Imaging
Takumi Kageyama, Yuji Ogura, Ikuo Hyodo, Yasushi Yatabe, Norihito Soga
A 69-year-old man was referred to our hospital with the chief complaint of a painless right scrotal swelling gradually increasing in size during the past 10 years. Testicular tumor markers were within the normal range. Ultrasonography showed an intrascrotal homogeneous mass. Computed tomography and magnetic resonance imaging revealed an inguinal mass, which mainly consisted of fat signal area and partially well enhanced in vascular density. Pre-surgical diagnosis was liposarcoma of spermatic cord estimated by radiographic examination and resection of the right intrascrotal tumor with high inguinal orchitectomy was performed...
September 2016: Hinyokika Kiyo. Acta Urologica Japonica
Tateki Yoshino, Koji Wake, Tomohiko Yamamoto, Hideyuki Onuma, Kazuo Kawakami
A 92-year-old man had noticed enlargement of a mass in the right scrotum and inguinal region for nine months. The patient was introduced to our department for right testicular tumor. Physical examination showed an over fist-sized, hard mass in the right scrotum. Magnetic resonance imaging (MRI) showed the mass, which consisted of fatty and solid contents. In addition, MRI revealed a bladder tumor simultaneously. Computed tomography revealed no distant metastases. The patient underwent right high orchiectomy with the mass resection and transurethral resection of the bladder tumor (TURBT)...
July 2016: Hinyokika Kiyo. Acta Urologica Japonica
Satoru Taguchi, Haruki Kume, Hiroshi Fukuhara, Teppei Morikawa, Shigenori Kakutani, Yuta Takeshima, Hideyo Miyazaki, Motofumi Suzuki, Tetsuya Fujimura, Tohru Nakagawa, Akira Ishikawa, Yasuhiko Igawa, Yukio Homma
The prognostic factors of retroperitoneal liposarcoma have yet to be clearly determined due to its rarity, whereas the prognostic value of symptoms at diagnosis has never been evaluated to date. In this context, we reviewed 24 consecutive patients with primary retroperitoneal liposarcoma who underwent surgical resection with curative intent at our institution. The Kaplan-Meier analysis and the log-rank test were used to estimate progression-free survival (PFS; primary endpoint) and sarcoma-specific survival (SSS; secondary endpoint)...
February 2016: Molecular and Clinical Oncology
E V Zolotareva, Yu Yu Andreeva, G A Frank, V I Rodionov
The paper reviews the literature on primary paratesticular tumors. It describes the classification, brief characteristics of liposarcomas and the morphological pattern of the tumor with an immunohistochemical profile. A clinical case of differentiated liposarcoma of the spermatic cord with myxoid and rhabdomyoblastic differentiation is depicted in a 61-year-old man.
May 2015: Arkhiv Patologii
Stefano Chiodini, Lorenzo G Luciani, Tommaso Cai, Alberto Molinari, Luca Morelli, Chiara Cantaloni, Mattia Barbareschi, Gianni Malossini
Liposarcoma accounts for 20% of all sarcomas and is a rare occurrence in the paratesticular region. We present the case of a 66-year-old man with a massive liposarcoma of the right scrotum invading the lower limb and the abdominal wall skin. The case concerns an unusually large and aggressive liposarcoma (25 cm), presenting with multiple lung and nodal metastases. The patient had an unfavourable evolution with rapid progression of metastases, although there were no signs of local disease. In this case, a wide local excision was performed in order to obtain local control of the disease...
March 2015: Archivio Italiano di Urologia, Andrologia
Zehani Alia, Chelly Ines, Azouz Haifa, Bellil Khedija, Haouet Slim, Kchir Nidhameddine
No abstract text is available yet for this article.
May 2014: La Tunisie Médicale
Maryam Abolhasani, Mashaallah Babashahi, Tina Shooshtarizadeh, Mojgan Asgari, Hossein Shahrokh, Pejman Shadpour, Maryam Emami
Spermatic cord liposarcomas are very rare tumors. Patients usually present with painless growing scrotal swellings which are clinically misdiagnosed as hernia. The correct diagnosis is not common and usually they present as operative or histological surprises. To our knowledge, there are about 186 similar cases reported in the literature. Herein we report three cases of spermatic cord liposarcoma with clinical presentation of scrotal bulging, mimicking inguinal hernia in one case and resembling a testicular tumor in the other two cases...
2014: Medical Journal of the Islamic Republic of Iran
Raimondo Gabriele, Giuseppe Ferrara, Maria Rita Tarallo, Alessio Giordano, Antonietta De Gori, Luciano Izzo, Marco Conte
Paratesticular liposarcomas are rare tumors that typically affect adult. Diagnosis is very difficult and inadequate surgical excision leads to a high rate of recurrence.We report a case of local recurrence of paratesticular liposarcoma diagnosed six months following surgery.Since there is low response to adjuvant treatments, extensive surgery remains the only curative approach, as shown by the case described here and the following review of the literature.
2014: World Journal of Surgical Oncology
Margarida Matias, Miguel Carvalho, Luisa Xavier, José Alberto Teixeira
Paratesticular sarcomas are rare and account for less than 1% of all adult sarcomas. Intrascrotal tumours can be testicular or paratesticular, paratesticular tumours being rarer (7-10%). Only 30% of paratesticular tumours are malignant and 90% of these are sarcomas. Histological subtypes include leiomyosarcoma, rhabdomyosarcoma, liposarcoma and undifferentiated high-grade pleomorphic sarcoma. Recurrence is frequent in this type of tumour and can occur years from initial diagnosis. These reports show two cases of paratesticular sarcoma with very distinct evolutions...
2014: BMJ Case Reports
Mohammed Raza, Hagadur Gurureddy Vinay, Mirzeeshan Ali, Gurubasappa Siddesh
Paratesticular liposarcomas are rare tumors and are often reported as isolated cases. Patients usually present with a painless scrotal or inguinal mass, mimicking inguinal hernia. They refer to liposarcomas arising from the spermatic cord, testicular tunics, and epididymis. We report a case of bilateral scrotal swelling which was misdiagnosed as inguinal hernia. Intraoperative diagnosis of testicular tumor was made. High inguinal orchiectomy was done. Histopathological examination revealed it to be liposarcoma of the cord...
January 2014: Journal of Surgical Technique and Case Report
Kalaivani Vinayagam, Vijayakumar Hosamath, Sridhar Honnappa, Aarathi Ranga Rau
Paratesticular liposarcomas are rare tumours which account for 12% of all liposarcomas. Probably there are about 186 cases which have been reported till date. They must be differentiated from tumours of testicular origin which have extension to the spermatic cord. We are reporting a case of a 50-year-old male who had presented with a painless swelling in the right hemiscrotum, which was of 20 years' duration. Inititally, a clinical diagnosis of testicular tumour was made; however, CT of the scrotum revealed paratesticular tumour? liposarcoma and testis being normal and displaced postero-inferiorly...
February 2014: Journal of Clinical and Diagnostic Research: JCDR
William Londeree, Tamie Kerns
This is a case of a 70-year-old male who presented with a mass in his right testicle. He was treated with antibiotics for epididymitis while undergoing serial ultrasounds for one year due to testicular swelling and pain. His fourth ultrasound revealed a mild hydrocele with a large paratesticular mass of undescribed size, superior to the right testicle, thought to be an inguinal hernia. Preoperative CT scan demonstrated a large fat-containing inguinal hernia extending into the scrotal sac. An inguinal hernia repair was complicated by fatty tissue surrounding the testicle requiring a right orchiectomy...
2014: Case Reports in Medicine
Jessica A Hemminger, Amanda Ewart Toland, Thomas J Scharschmidt, Joel L Mayerson, Denis C Guttridge, O Hans Iwenofu
Myxoid and round-cell liposarcoma is a frequently encountered liposarcoma subtype. The mainstay of treatment remains surgical excision with or without chemoradiation. However, treatment options are limited in the setting of metastatic disease. Cancer-testis antigens are immunogenic antigens with the expression largely restricted to testicular germ cells and various malignancies, making them attractive targets for cancer immunotherapy. Gene expression studies have reported the expression of various cancer-testis antigens in liposarcoma, with mRNA expression of CTAG1B, CTAG2, MAGEA9, and PRAME described specifically in myxoid and round-cell liposarcoma...
September 2014: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Leona A Doyle, Derrick Tao, Adrián Mariño-Enríquez
A recurrent intrachromosomal rearrangement on chromosome 12q in solitary fibrous tumor leads to the formation of a NAB2-STAT6 fusion oncogene. As a result, nuclear expression of the cytoplasmic transcription factor STAT6 is found in solitary fibrous tumor and serves as a useful diagnostic marker. STAT6 is located in 12q13, a region containing well-characterized oncogenes that are commonly amplified in dedifferentiated liposarcoma; we have previously reported that STAT6 is expressed in a subset of dedifferentiated liposarcoma...
September 2014: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Sophia K McKinley, Nicolas Abreu, Eva Patalas, Arthur Chang
While inguinal hernia is common in the primary care office, the differential diagnosis is extensive and includes infectious, inflammatory and neoplastic processes. Varicocele is another frequent, generally benign condition which occasionally reflects serious disease entities. Left-sided or bilateral varicoceles account for the overwhelming majority of varicoceles because the left gonadal vein drains into the left renal vein in contrast to the right gonadal vein, which drains directly into the inferior vena cava, thus making left-sided or bilateral venous congestion more likely...
2013: Case Reports in Radiology
Filip Vukmirović, Nihad Zejnilović, Jovan Ivović
INTRODUCTION: Liposarcomas are malignant tumors derived from fat tissues. Liposarcoma of the paratesticular tissue is rare. CASE REPORT: We presented a 51-year-old man with liposarcoma of paratesticular tissue and the spermatic cord, mimicking a testicular tumor. Ultrasound examination of this scrotal mass was hyperechogenic and homogeneous and separated from the testis and epididymis. The patient was operated, and the orchidectomy was performed. Histology revealed well-differentiated lipoma-like liposarcoma of the paratesticular tissue and spermatic cord...
July 2013: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Kazuhito Hatanaka, Takako Yoshioka, Takashi Tasaki, Akihide Tanimoto
UNLABELLED: Paratesticular liposarcoma is a rare neoplasm, described in single case studies or components of larger studies, as histologically well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DL). However, leiomyosarcomatous differentiation is an extremely rare occurrence in WDL and DL. We report a case of leiomyosarcomatous differentiation in a 77-year-old man. The patient presented with a painless right scrotal mass. Magnetic resonance imaging showed a large mass along the right spermatic cord...
2013: Diagnostic Pathology
Alfredo D'Andrea, Francesco Coppolino, Elviro Cesarano, Anna Russo, Salvatore Cappabianca, Eugenio Annibale Genovese, Paolo Fonio, Luca Macarini
BACKGROUND: The acute scrotum is a medical emergency . The acute scrotum is defined as scrotal pain, swelling, and redness of acute onset. Scrotal abnormalities can be divided into three groups , which are extra-testicular lesion, intra-testicular lesion and trauma. This is a retrospective analysis of 164 ultrasound examination performed in patient arriving in the emergency room for scrotal pain.The objective of this article is to familiarize the reader with the US features of the most common and some of the least common scrotal lesions...
July 15, 2013: Critical Ultrasound Journal
Xiao-Rong Wen, Jing Huang, Yang Chen, Kun-Jie Wang, Yong-Zhong Li
OBJECTIVE: To study the ultrasound imaging characteristics of scrotum sarcoma. METHODS: Retrospective analyses of the ultrasound and clinical data of 9 patients with scrotum sarcoma were performed. RESULTS: Of the 9 patients, 5 had scrotum rhabdomyosarcoma, which included 2 cases of alveolus rhabdomyosarcoma and 3 cases of embryonic rhabdomyosarcoma (including 2 embryonic rhabdomyosarcoma of the tunica dartos in the scrotum). Their ultrasound imaging showed single or multiple hypoechoic mass located in the scrotum with distinct boundary and vascularity within the tumor...
May 2013: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
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