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https://www.readbyqxmd.com/read/29202922/simultaneous-analysis-of-multiple-allergens-in-food-products-by-lc-ms-ms
#1
Lee Sun New, Andre Schreiber, Jianru Stahl-Zeng, Hua-Fen Liu
There is currently no cure for food allergies, and sufferers can only rely on the correct labeling of foods toavoid allergens. Hence, it is important that analytical methods are sensitive and accurate enough to screen for the presence of multiple allergens in food products. In this study, we developed an LC-tandem MS method that is able to simultaneously screen or quantify the signature tryptic peptides of multiple allergen commodities. This method is capable of screening and identifying egg white, skim milk, peanut, soy, and tree nuts (almond, Brazil nut, cashew, hazelnut, pecan, pine nut, pistachio, and walnut) at a detection limit of 10 ppm in incurred bread and cookies...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29186859/peanuts-aflatoxins-and-undernutrition-in-children-in-sub-saharan-africa
#2
REVIEW
Innocent Mupunga, Pamella Mngqawa, David R Katerere
Peanuts (Arachis hypogaea) is an important and affordable source of protein in most of Sub-Saharan Africa (SSA) and a popular commodity and raw material for peanut butter, paste and cooking oil. It is a popular ingredient for foods used at the point of weaning infants from mother's milk. It is at this critical point that childhood undernutrition occurs and the condition manifests as stunting, wasting and growth restriction and accounts for nearly half of all deaths in children under five years of age in SSA...
November 26, 2017: Nutrients
https://www.readbyqxmd.com/read/29168062/tree-nut-peanut-and-peanut-butter-intake-and-risk-of-postmenopausal-breast-cancer-the-netherlands-cohort-study
#3
Piet A van den Brandt, Lisette Nieuwenhuis
PURPOSE: Nut intake has been associated with reduced mortality and risk of cardiovascular diseases, but there is only limited evidence on cancer. We investigated the relationship between nut intake and risk of postmenopausal breast cancer, and estrogen/progesterone receptor (ER/PR) subtypes. METHODS: In The Netherlands Cohort Study, 62,573 women aged 55-69 years provided information on dietary and lifestyle habits in 1986. After 20.3 years of follow-up, 2,321 incident breast cancer cases and 1,665 subcohort members were eligible for multivariate case-cohort analyses...
November 22, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29130802/oral-immunotherapy-using-polymeric-nanoparticles-loaded-with-peanut-proteins-in-a-murine-model-of-fatal-anaphylaxis
#4
Carlos Gamazo, Maddi García-Azpíroz, Juliana De Souza Rebouças, Gabriel Gastaminza, Marta Ferrer, Juan M Irache
BACKGROUND: Peanut allergy is the most common cause of anaphylaxis and food-related death. However, there is currently no approved immunotherapy treatment. Hence, this warrants the need for relevant and convenient animal models to test for adequate immunotherapies. MATERIALS & METHODS: In this study, we compared three mouse strains: CD1, BALB/c and C57, to select a model of peanut allergy. After that, we conducted then a therapeutic study using an immunogenic peanut extract encapsulated in nanoparticles made with polymer Gantrez(®) following the solvent displacement method...
November 2017: Immunotherapy
https://www.readbyqxmd.com/read/29026953/application-of-molecularly-imprinted-polymers-for-the-analysis-of-polycyclic-aromatic-hydrocarbons-in-lipid-matrix-based-biological-samples
#5
Ying Sun, Yiming Pang, Jingxu Zhang, Zhiwen Li, Jufen Liu, Bin Wang
High-accuracy analyses of polycyclic aromatic hydrocarbons (PAHs) in lipid matrix-based biological samples are highly necessary. We investigated the cleanup performance of the commercially available molecularly imprinted polymers (MIPs) to analyze PAHs in various biological samples (i.e., butter, peanut oil, pork belly, and human umbilical cord), and compared this method with the commonly used gel permeation chromatography (GPC). After primary cleanup with a MIP or GPC column, the extracts were further cleaned with a neutral aluminum oxide column...
October 12, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28938036/please-pass-the-peanut-butter
#6
Rochelle P Walensky
No abstract text is available yet for this article.
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28917229/peanut-butter-increases-the-bioavailability-and-bioconversion-of-kale-%C3%AE-carotene-to-vitamin-a
#7
Tawanda Muzhingi, Kyung-Jin Yeum, Odilia Bermudez, Guangwen Tang, Andrew Hlanganiso Siwela
BACKGROUND AND OBJECTIVES: Kale is a rich source of provitamin A- β-carotene. This study used intrinsically labeled kale [2H9] β-carotene to determine the effect of peanut butter on the bioconversion of kale β-carotene to vitamin A in preschool children. METHODS AND STUDY DESIGN: Preschool children (n=37; age 12-36 mo) were randomly assigned to 50 g cooked kale (1.5 mg β-carotene content) with either 33 g peanut butter (PBG) or with 16 g lard (LG) and a reference dose of 1 mg [13C10] retinyl acetate capsule...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28768652/nut-and-peanut-butter-consumption-and-the-risk-of-esophageal-and-gastric-cancer-subtypes
#8
Maryam Hashemian, Gwen Murphy, Arash Etemadi, Sanford M Dawsey, Linda M Liao, Christian C Abnet
Background: Nut consumption has been associated with decreased risk of colorectal, endometrial, lung, and pancreatic cancers. Polyphenols, fiber, vitamins, and minerals in nuts may confer this observed protective effect. To our knowledge, no prospective study has evaluated the effect of nut consumption on esophageal and gastric cancers.Objective: The objective was to evaluate the associations between nut and peanut butter consumption and the risk of esophageal and gastric cancers and their different subtypes...
September 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28709968/specific-allergen-profiles-of-peanut-foods-and-of-diagnostic-or-therapeutic-allergenic-products
#9
Stephanie Filep, Denise Block, Bryan R E Smith, Eva M King, Scott Commins, Michael Kulis, Brian P Vickery, Martin D Chapman
RATIONALE: 'Generic' immunoassays for peanut cannot discriminate between allergen levels in peanut derived food products or therapeutics. Clinical trials of oral immunotherapy are strengthened by using standardized peanut preparations, with defined doses of major allergens. OBJECTIVE: This paper describes measurement of Ara h 1, Ara h 2 and Ara h 6 in peanut foods and in peanut flour extracts used for allergy diagnosis and oral immunotherapy. METHODS: Monoclonal antibody-based enzyme immunoassays for Ara h 1, Ara h 2 and Ara h 6 were used to compare allergen levels in peanut (n=19) and tree nut (n=16) butter, peanut flour (n=11); oils (n=8); extracts used for diagnosis and oral immunotherapy (n=5); and the National Institute for Standards and Technology Peanut Butter Standard Reference Material® 2387...
July 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28676973/chronic-consumption-of-fructose-in-combination-with-trans-fatty-acids-but-not-with-saturated-fatty-acids-induces-nonalcoholic-steatohepatitis-with-fibrosis-in-rats
#10
Sugeedha Jeyapal, Uday Kumar Putcha, Venkata Surekha Mullapudi, Sudip Ghosh, Anil Sakamuri, Suryam Reddy Kona, Sai Santosh Vadakattu, Chandana Madakasira, Ahamed Ibrahim
PURPOSE: Consumption of Western diet high in fat and fructose has been attributed to the recent epidemic of nonalcoholic fatty liver disease (NAFLD). However, the impact of specific fatty acids on the progression of NAFLD to nonalcoholic steatohepatitis (NASH) is poorly understood. In the present study, we investigated the chronic effects of consumption of fructose in combination with saturated fatty acids (SFA) or trans fatty acids (TFA) on the development of NAFLD. METHODS: Male Sprague-Dawley rats were randomly assigned to six isocaloric starch/high fructose (44% of calories), high fat (39% calories) diet containing either starch-peanut oil, fructose-peanut oil, fructose-palmolein, fructose-clarified butter, fructose-coconut oil or fructose-partially hydrogenated vegetable oil and fed for 24 weeks...
July 4, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28535077/sticky-situations-cyanoacrylate-exposures-reported-to-a-poison-control-system
#11
Shaun D Carstairs, Cynthia Koh, Lily Qian, Mariam Qozi, Grant Seivard, F Lee Cantrell
INTRODUCTION: Cyanoacrylate (Super Glue(®)) exposures are commonly reported to poison control centers, but little has been published in the medical literature regarding these exposures. We sought to characterize cyanoacrylate exposures reported to a poison control system. METHODS: We performed a retrospective review of a poison system's database for all cases of single-substance human exposure to cyanoacrylate-containing products from 2005 to 2015. Data collected included age, gender, route of exposure, clinical effects, treatments recommended and medical outcome...
November 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28520477/minimum-stocking-requirements-for-retailers-in-the-special-supplemental-nutrition-program-for-women-infants-and-children-disparities-across-us-states
#12
Jennifer E Pelletier, Liana R N Schreiber, Melissa N Laska
OBJECTIVES: To examine state variation in minimum stocking requirements for Special Supplemental Nutrition Program for Women, Infants, and Children (WIC)-authorized small food retailers. METHODS: We obtained minimum stocking requirements for 50 states and the District of Columbia in 2017 from WIC Web pages or e-mail from the state WIC agency. We developed a coding protocol to compare minimum quantities and varieties required for 12 food and beverage categories. We calculated the median, range, and interquartile range for each measure...
July 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28508267/will-it-be-cheese-bologna-or-peanut-butter
#13
Walter C Willett
No abstract text is available yet for this article.
April 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28492845/a-simple-effective-analogy-to-elucidate-the-mohs-micrographic-surgery-procedure-the-peanut-butter-cup
#14
Elizabeth Lee, Jay E Wolverton, Ally-Khan Somani
No abstract text is available yet for this article.
August 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28469710/single-nucleotide-polymorphism-typing-analysis-for-molecular-subtyping-of-salmonella-tennessee-isolates-associated-with-the-2007-nationwide-peanut-butter-outbreak-in-the-united-states
#15
Hee-Jin Dong, Seongbeom Cho, David Boxrud, Shelly Rankin, Francis Downe, Judith Lovchik, Jim Gibson, Matt Erdman, A Mahdi Saeed
BACKGROUND: In 2007, a nationwide Salmonella Tennessee outbreak occurred via contaminated peanut butter. Here, we developed a single-nucleotide polymorphism (SNP)-typing method for S. Tennessee to determine the clonal subtypes of S. Tennessee that were associated with the peanut butter outbreak. METHODS AND RESULTS: One seventy-six S. Tennessee isolates from various sources, including humans, animals, food, and the environment, were analyzed by using the SNP technique...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28431184/editor-s-highlight-congener-specific-disposition-of-chiral-polychlorinated-biphenyls-in-lactating-mice-and-their-offspring-implications-for-pcb-developmental-neurotoxicity
#16
Izabela Kania-Korwel, Tracy Lukasiewicz, Christopher D Barnhart, Marianna Stamou, Haeun Chung, Kevin M Kelly, Stelvio Bandiera, Pamela J Lein, Hans-Joachim Lehmler
Chiral polychlorinated biphenyl (PCB) congeners have been implicated by laboratory and epidemiological studies in PCB developmental neurotoxicity. These congeners are metabolized by cytochrome P450 (P450) enzymes to potentially neurotoxic hydroxylated metabolites (OH-PCBs). The present study explores the enantioselective disposition and toxicity of 2 environmentally relevant, neurotoxic PCB congeners and their OH-PCB metabolites in lactating mice and their offspring following dietary exposure of the dam. Female C57BL/6N mice (8-weeks old) were fed daily, beginning 2 weeks prior to conception and continuing throughout gestation and lactation, with 3...
July 1, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28366815/liraglutide-suppression-of-caloric-intake-competes-with-the-intake-promoting-effects-of-a-palatable-cafeteria-diet-but-does-not-impact-food-or-macronutrient-selection
#17
Kellie M Hyde, Ginger D Blonde, Carel W le Roux, Alan C Spector
Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is used as a treatment for Type 2 diabetes mellitus and obesity because it improves glycemia and decreases food intake. Here, we tested whether chronic activation of the GLP-1 receptor system with liraglutide would induce decreases in intake accompanied by changes in proportional food or macronutrient intake similar to those seen following RYGB in rats when a variety of palatable food options are available. A "cafeteria diet" was used that included: laboratory rodent chow, refried beans (low-fat/low-sugar), low-fat yogurt (low-fat/high-sugar), peanut butter (high-fat/low-sugar) and sugar-fat whip (high-fat/high-sugar)...
August 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28343725/newly-developed-method-for-mouse-olfactory-behavior-tests-using-an-automatic-video-tracking-system
#18
Hyung-Ju Cho, Yong Hyuk Lee, Bo Ra Kim, Hong-Kyung Kim, Hyo Jin Chung, Sang Chul Park, Je Kyung Seong, Joo-Heon Yoon, Chang-Hoon Kim
OBJECTIVE: The mouse is the most popular animal model in olfactory research. Behavior tests with odorants are essential for determining olfactory phenotype. To the best of our knowledge, the mouse olfactory behavior test has not been standardized, making the results vulnerable to inter-observer variation. We sought to develop a new mouse olfactory behavior test assessed by an automatic video tracking system with minimal inter-observer variation. METHODS: A video-tracking system was used to automatically track mouse behavior in standard breeding cages with C57BL/6N mice...
March 23, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28266703/changes-to-infant-feeding-guidelines-relevance-to-dermatologists
#19
REVIEW
Celestine C Wong, Katrina J Allen, David Orchard
The newly revised Australian Infant Feeding Guidelines recommends that all infants, including those at high risk of allergy, be introduced foods traditionally considered allergenic (such as peanut butter, dairy, wheat and egg) within the first year of life. High-risk infants are those with early onset eczema (<3-months old) or with moderate to severe eczema not responding to treatment (<6-months old). Eczema can also represent a symptom of allergy presentation and the recommended introduction of some foods in this group may lead to allergic reactions at home...
November 2017: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/28194094/food-seeking-in-a-risky-environment-a-method-for-evaluating-risk-and-reward-value-in-food-seeking-and-consumption-in-mice
#20
Sarah H Lockie, Clare V McAuley, Sasha Rawlinson, Natalie Guiney, Zane B Andrews
Most studies that measure food intake in mice do so in the home cage environment. This necessarily means that mice do not engage in food seeking before consumption, a behavior that is ubiquitous in free-living animals. We modified and validated several commonly used anxiety tests to include a palatable food reward within the anxiogenic zone. This allowed us to assess risk-taking behavior in food seeking in mice in response to different metabolic stimuli. We modified the open field test and the light/dark box by placing palatable peanut butter chips within a designated food zone inside the anxiogenic zone of each apparatus...
2017: Frontiers in Neuroscience
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