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Pediatric urologic oncology

Leszek Komasara, Joanna Stefanowicz, Anna Bryks-Laszkowska, Andrzej Gołębiewski, Piotr Czauderna
OBJECTIVES: To present versatile surgical reconstructive techniques and their outcomes in pediatric patients with genitourinary rhabdomyosarcoma. METHODS: We retrospectively analyzed the oncological and urological outcomes of seven patients treated between 1992 and 2014 according to the Cooperative Weichteilsarkom Studiengruppe protocols. Intergroup Rhabdomyosarcoma Study staging: local, six patients; and IV, one patient. HISTOLOGY: embryonal, five patients; unclassified, one patient; triton tumor one patient...
August 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
Shakilu Iumanne, Aika Shoo, Larry Akoko, Patricia Scanlan
BACKGROUND: Xanthogranulomatous pyelonephritis (XGP) is a rare renal tumor that arises as a complication of chronic obstructive pyelonephritis of uncertain etiology. It is primarily an adult tumor seen occasionally in children associated with urinary tract obstruction due to congenital urological anomalies, nephrolithiasis, and recurrent urinary tract infections. Radiologically, it may show neoplastic features such as those seen in common pediatric renal malignancies like wilms' tumor and renal cell carcinoma...
2016: BMC Urology
Armando J Lorenzo, Rodrigo L P Romao
OBJECTIVE: This review aims at evaluating the current status of minimally invasive surgery at the difficult crossroad between the attractiveness of innovation faced against the solid outcomes offered by the current gold standard, specifically concerning pediatric and adolescent urologic oncology conditions. METHODS: This is a critical review of the literature and current paradigms on the use of minimally invasive surgery for pediatric and adolescent urologic oncology cancers...
May 2016: Urology
Nicholas G Cost, Jeffrey A Stock
No abstract text is available yet for this article.
May 2016: Urology
Fernando Ferrer
No abstract text is available yet for this article.
February 2016: Urologic Oncology
Nicholas G Cost, Jeffrey A Stock
No abstract text is available yet for this article.
February 2016: Urologic Oncology
Nicholas G Cost, Jeffrey A Stock
No abstract text is available yet for this article.
January 2016: Urologic Oncology
Jonathan H Ross
At most institutions, pediatric urologists play a limited role in the care of children with cancer. Pediatric urologists have a unique experience and skill set to contribute to the care of these patients. Interested pediatric urologists should become experts in pediatric urologic oncology and demonstrate this interest by participating in tumor board and relevant academic activities. They should advocate for a collaborative approach with pediatric general surgeons in the surgical management of children with genitourinary as such an approach benefits patient care, contributes to professional development of all parties, and develops relationships that contribute to programmatic development for the institution in oncology and other areas...
January 2016: Urologic Oncology
Christian Piolat, Frédéric Lavrand, Sabine Sarnacki
Thoracic surgery for pediatric tumors may induce a large variety of sequelae that mainly concern skin, muscles and bones (ribs), thoracic nerve and spinal cord and respiratory system. Muscle-sparing thoracotomy, intrathoracic expanders inserted after right pneumonectomy, early orthopedic evaluation and follow-up are useful preventive proceedings able to decrease postoperative sequelae. Surgery for abdominal tumors in children is part of a sequence where each therapeutic treatment can induce its own sequelae possibly potentiated by other therapies...
July 2015: Bulletin du Cancer
Matthieu Peycelon, Georges Audry, Sabine Irtan
INTRODUCTION: Minimally invasive surgery (MIS) has emerged as an alternative to open approach for cancer diagnosis in children ∼20 years ago, but only recently for tumor resection. The purpose of this review is to update the use of MIS in pediatric oncological surgery over the past five years. METHODS: The authors conducted a systematic review of papers published between 2009 and 2014 focusing on indications and results of the technique. RESULTS: New indications in Wilms tumor, pheochromocytoma, and lung nodules have emerged, thanks to the growing use of MIS in benign urological and thoracic surgery with satisfactory results...
December 2014: European Journal of Pediatric Surgery
Joanna Kemp, Miguel A Guzman, Colleen M Fitzpatrick, Samer K Elbabaa
BACKGROUND AND IMPORTANCE: Anterior sacral meningoceles are lesions that are uncommonly reported and can be associated with other pathology including presacral masses, tethered spinal cord, and syringomyelia. Tethered spinal cord and syringomyelia can result in neurologic deficits, while large meningoceles and presacral masses can have gastroenterologic, urologic, reproductive, and oncologic consequences. CLINICAL PRESENTATION: The authors report a case of a 14-year-old girl with an anterior sacral meningocele, tailgut cyst, and tethered cord with holocord syringomyelia who presented with a tethered cord syndrome, manifested by constipation, urinary retention, bilateral lower extremity weakness, and sensory deficits...
June 2014: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Francisco Tibor Dénes, Ricardo Jordão Duarte, Lílian Maria Cristófani, Roberto Iglesias Lopes
Tumors of the kidney, bladder, prostate, testis, and adrenal represent a large part of the adult urologic practice, but are relatively infrequent in children. The natural history and management of these tumors in the pediatric age is different from that of the adults. As result of the successful work of several clinical trial groups in recent decades, there has been a significant improvement in their cure rates. The aim of this article is to review their most significant clinical aspects, as well as to present an update in their management...
2013: Frontiers in Pediatrics
T Kutluk, K Mutlu Hayran, S Kilickap, D Yuce, I Celik, M Erman, S Yalcin
PURPOSE: High-quality hospital-based cancer registry systems are the key elements of a healthy population-based cancer data. The purpose of this study was to present a recent history of establishing a valuable and reliable hospital- based cancer registry in a university hospital in Turkey, and the data gathered by this system in the last 9 years. METHODS: This study included the cancer registry records of Hacettepe University Hospitals between 1-Jan-2003, and 31-Dec-2011...
October 2013: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Jason R Woo, David Sisul, George Kaplan, George Chiang
PURPOSE: To evaluate long-term urologic outcomes of patients with pelvic neuroblastoma (NB) presenting with urinary retention. METHODS: Five cases of pelvic NB presenting with urinary retention were identified between 1971 and 2011. Clinical presentation, treatment, survival and long-term voiding outcomes were analyzed. RESULTS: All five patients presented with acute urinary retention and pelvic outlet dysfunction including bladder perforation (20%), constipation (40%), or fecal incontinence (20%)...
October 2013: Pediatric Hematology and Oncology
Edward J Nehus, Benjamin L Laskin, Thelma I Kathman, John J Bissler
BACKGROUND: Limited data exist on the performance of cystatin C-based glomerular filtration rate (GFR) equations in pediatric transplant recipients and other high-risk patients. The aim of our study was therefore to evaluate the performance of current cystatin C-based equations in this population. METHODS: This was a retrospective, cross-sectional study of 141 consecutive patients (58 % post-transplant) who received a nuclear medicine GFR (NucGFR) examination using (99m)Tc- diethylenetriaminepentaacetic acid at our institution...
March 2013: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Nicholas G Cost, Carrye R Cost, James I Geller, W Robert Defoor
Recent Surveillance Epidemiology and End Results (SEER) data indicate that the annual cancer incidence in adolescents is higher than in children, and is on the rise. However, the amount of attention, research funding, and therapeutic progress made in the adolescent oncology population pales in comparison with that of pediatric oncology. Issues of adolescent oncology have only recently been acknowledged by leaders in the field, and current efforts now focus on raising awareness of this unique patient group. In urology, there have been many gains made in pediatric urologic oncology, most notably in Wilms tumor and genitourinary rhabdomyosarcoma (genitourinary [GU] rhabdomyosarcoma [RMS]); however, there has been little to no progress in the adolescent population...
February 2014: Urologic Oncology
Gwen M Grimsby, Michael L Ritchey
This article reviews common pediatric urologic cancers involving the genitourinary system. Rhabdomyosarcoma may occur in the bladder, prostate, paratesticular regions, vagina, or uterus. Some of these locations, such as the paratesticular region, have a more favorable outcome. Benign neoplasms account for the majority of pediatric testicular tumors and most are managed with testis-sparing surgery. Most genitourinary malignancies are expected to have a good outcome. One focus of treatment is organ preservation but not at the expense of a good oncologic outcome...
August 2012: Pediatric Clinics of North America
E Ann Gormley
Urology has always been seen as being on the cutting edge of technology and this has been especially prevalent in the past 10 to 15 years with a move to robotic surgery, increased use of laser technology, and stem cell research leading to organ regeneration. Urology has a number of subspecialties including pediatrics, urologic oncology, renal transplantation, male infertility and andrology, calculi, female urology, neurourology, and trauma and reconstruction. Urologists have a wide array of practice options ranging from performing major oncologic procedures with extensive reconstruction to having an office-based practice and performing endoscopic cases with everything else in between...
July 2012: American Journal of Surgery
Jason R Axt, Andrew J Murphy, Patrick G Arbogast, Harold N Lovvorn
INTRODUCTION: Adults undergoing oncologic resections at low-volume centers experience increased perioperative morbidity and mortality. The volume-outcome effect has not been extensively studied in pediatric oncologic resections. METHODS: To clarify volume-outcome effects in pediatric oncologic resections, we analyzed resection of renal malignancies in children less than 15 y of age. We conducted a cross-sectional analysis of hospital discharges included in the health care utilization project kids' inpatient database from 1997 to 2009, examining in-hospital operative complications, length of stay (LOS), and inflation-adjusted hospital charges...
September 2012: Journal of Surgical Research
Frederic H Fahey, S Ted Treves, S James Adelstein
The value of pediatric nuclear medicine is well established. Pediatric patients are referred to nuclear medicine from nearly all pediatric specialties including urology, oncology, cardiology, gastroenterology, and orthopedics. Radiation exposure is associated with a potential, small, risk of inducing cancer in the patient later in life and is higher in younger patients. Recently, there has been enhanced interest in exposure to radiation from medical imaging. Thus, it is incumbent on practitioners of pediatric nuclear medicine to have an understanding of dosimetry and radiation risk to communicate effectively with their patients and their families...
March 2012: Journal of Nuclear Medicine Technology
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