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https://www.readbyqxmd.com/read/27933638/nursing-interventions-for-smoking-cessation-in-hospitalized-patients-a-systematic-review
#1
REVIEW
Z Kazemzadeh, Z S Manzari, Z Pouresmail
AIM: This study aimed to clarify the role of nurses in planning and implementation of nursing interventions related to smoking cessation. BACKGROUND AND INTRODUCTION: Nearly half of all smokers die from smoking-related illnesses. Quitting smoking can reduce these problems. Smoking cessation interventions include various types helping smokers successfully quit. Studies suggest that hospitalization can be a golden opportunity for nurses helping patients to quit smoking because of No Smoking regulations...
December 9, 2016: International Nursing Review
https://www.readbyqxmd.com/read/27886972/the-resident-run-minor-surgery-clinic-a-pilot-study-to-safely-increase-operative-autonomy
#2
REVIEW
Brandon M Wojcik, Zhi Ven Fong, Madhukar S Patel, David C Chang, Emil Petrusa, John T Mullen, Roy Phitayakorn
OBJECTIVE: General surgery training has evolved to align with changes in work hour restrictions, supervision regulations, and reimbursement practices. This has culminated in a lack of operative autonomy, leaving residents feeling inadequately prepared to perform surgery independently when beginning fellowship or practice. A resident-run minor surgery clinic increases junior resident autonomy, but its effects on patient outcomes have not been formally established. This pilot study evaluated the safety of implementing a resident-run minor surgery clinic within a university-based general surgery training program...
November 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27871921/eeg-frequency-tagging-using-ultra-slow-periodic-heat-stimulation-of-the-skin-reveals-cortical-activity-specifically-related-to-c-fiber-thermonociceptors
#3
Elisabeth Colon, Giulia Liberati, André Mouraux
The recording of event-related brain potentials triggered by a transient heat stimulus is used extensively to study nociception and diagnose lesions or dysfunctions of the nociceptive system in humans. However, these responses are related exclusively to the activation of a specific subclass of nociceptive afferents: quickly-adapting thermonociceptors. In fact, except if the activation of Aδ fibers is avoided or if A fibers are blocked, these responses specifically reflect activity triggered by the activation of Type 2 quickly-adapting A fiber mechano-heat nociceptors (AMH-2)...
November 19, 2016: NeuroImage
https://www.readbyqxmd.com/read/27865989/drug-delivery-across-intact-and-disrupted-skin-barrier-identification-of-cell-populations-interacting-with-penetrated-thermoresponsive-nanogels
#4
F Rancan, M Giulbudagian, J Jurisch, U Blume-Peytavi, M Calderón, A Vogt
Nanoscaled soft particles, such as nanogels, can be designed to incorporate different types of compounds and release them in a controlled and triggered manner. Thermoresponsive nanogels (tNG), releasing their cargo above a defined temperature, are promising carrier systems for inflammatory skin diseases, where the temperature of diseased skin differs from that of healthy skin areas. In this study a polyglycerol-based tNG with diameter of 156 nm was investigated for penetration and release properties upon topical application on ex vivo human skin with intact or disrupted barrier...
November 16, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27851645/2011-skin-tags-benign-entities-leading-to-a-deadly-condition
#5
Ann John, Elizabeth John, William Lambert
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27829444/potential-molecular-characteristics-in-situ-in-response-to-repetitive-uvb-irradiation
#6
Wenqi Chen, Jinhai Zhang
BACKGROUND: To identify molecular characteristics in situ in response to repetitive UVB (ultraviolet-B) irradiation. METHODS: Microarray data from the Gene Expression Omnibus were re-analyzed to identify DEGs (differentially expressed genes) between UVB-irradiated and non-irradiated skin biopsies. Enrichment and annotation analyses were performed respectively using DAVID, and TSGene and TAG databases. PPIs (protein-protein interactions) were analyzed using STRING, and miRNAs (microRNAs) and TFs (transcription factors) were predicted separately by miRNA-related databases and ENCODE...
November 10, 2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27815622/-cutaneous-manifestations-of-metabolic-syndrome
#7
REVIEW
G Holzer, B Straßegger, B Volc-Platzer
BACKGROUND: Metabolic syndrome (MetS) is a cluster of risk factors which increase the risk of developing cardiovascular diseases and type II diabetes mellitus. High blood pressure, hyperglycemia, dyslipidemia, and central obesity are the main risk factors. While MetS is not a dermatological diagnosis per se, several cutaneous manifestations can serve as a clinical indicator for impending MetS and facilitate an early diagnosis and therapy in order to prevent its long-term sequelae...
December 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27755556/muscadine-grape-skin-extract-induces-an-unfolded-protein-response-mediated-autophagy-in-prostate-cancer-cells-a-tmt-based-quantitative-proteomic-analysis
#8
Liza J Burton, Mariela Rivera, Ohuod Hawsawi, Jin Zou, Tamaro Hudson, Guangdi Wang, Qiang Zhang, Luis Cubano, Nawal Boukli, Valerie Odero-Marah
Muscadine grape skin extract (MSKE) is derived from muscadine grape (Vitis rotundifolia), a common red grape used to produce red wine. Endoplasmic reticulum (ER) stress activates the unfolded protein response (UPR) that serves as a survival mechanism to relieve ER stress and restore ER homeostasis. However, when persistent, ER stress can alter the cytoprotective functions of the UPR to promote autophagy and cell death. Although MSKE has been documented to induce apoptosis, it has not been linked to ER stress/UPR/autophagy...
2016: PloS One
https://www.readbyqxmd.com/read/27755235/late-recognition-of-a-case-of-oculo-auriculo-vertebral-spectrum
#9
Jeylan El Mansoury, Joyce N Mbekeani
PURPOSE: To report the late recognition of a case oculo-auriculo-vertebral spectrum (OAVS). CASE REPORT: A 14-year-old male patient with a history of spinal scoliosis and anal atresia presented with a right ocular growth that was increasing in size and causing irritation. He was discovered to have a right limbal dermoid and forniceal lipodermoid. All visual functions were normal and the rest of the anterior and posterior segments were unremarkable. External examination revealed facial asymmetry and ipsilateral hemifacial microsomia and a pre-auricular skin tag...
October 13, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27723447/anal-health-care-basics
#10
Jason Chang, Elisabeth Mclemore, Talar Tejirian
Despite the fact that countless patients suffer from anal problems, there tends to be a lack of understanding of anal health care. Unfortunately, this leads to incorrect diagnoses and treatments. When treating a patient with an anal complaint, the primary goals are to first diagnose the etiology of the symptoms correctly, then to provide an effective and appropriate treatment strategy.The first step in this process is to take an accurate history and physical examination. Specific questions include details about bowel habits, anal hygiene, and fiber supplementation...
2016: Permanente Journal
https://www.readbyqxmd.com/read/27688981/a-method-for-high-precision-sequencing-of-near-full-length-16s-rrna-genes-on-an-illumina-miseq
#11
Catherine M Burke, Aaron E Darling
BACKGROUND: The bacterial 16S rRNA gene has historically been used in defining bacterial taxonomy and phylogeny. However, there are currently no high-throughput methods to sequence full-length 16S rRNA genes present in a sample with precision. RESULTS: We describe a method for sequencing near full-length 16S rRNA gene amplicons using the high throughput Illumina MiSeq platform and test it using DNA from human skin swab samples. Proof of principle of the approach is demonstrated, with the generation of 1,604 sequences greater than 1,300 nt from a single Nano MiSeq run, with accuracy estimated to be 100-fold higher than standard Illumina reads...
2016: PeerJ
https://www.readbyqxmd.com/read/27647359/cutaneous-problems-in-elderly-diabetics-a-population-based-comparative-cross-sectional-survey
#12
N Asokan, V G Binesh
BACKGROUND: There are few population-based studies on prevalence of cutaneous problems in diabetes mellitus. AIMS: To identify skin problems associated with diabetes mellitus among elderly persons in a village in Kerala. METHODS: In this population-based cross-sectional survey, we compared the prevalence of skin problems among 287 elderly diabetics (aged 65 years or more) with 275 randomly selected elderly persons without diabetes mellitus...
September 20, 2016: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/27646399/ep10-08-three-dimensional-prenatal-diagnosis-of-lateral-facial-cleft-and-preauricular-skin-tags
#13
D Atanassova, E Pavlova, I Markova, P Markov, V Stoykova, D Markov, S Patishanov, G Radinski
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27551823/large-scale-recombinant-expression-and-purification-of-human-tyrosinase-suitable-for-structural-studies
#14
Xuelei Lai, Montserrat Soler-Lopez, Harry J Wichers, Bauke W Dijkstra
Human tyrosinase (TYR) is a glycoprotein that initiates the first two reactions in the melanin biosynthesis pathway. Mutations in its encoding gene cause Oculocutaneous Albinism type I (OCA1), the most severe form of albinism, which is a group of autosomal recessive disorders characterized by reduced or absent production of melanin in skin, hair and eyes. Despite extensive structural and characterization studies of its homologues in lower eukaryotic organisms, the catalytic mechanism of human TYR and the molecular basis of OCA1 are largely unknown...
2016: PloS One
https://www.readbyqxmd.com/read/27522318/male-and-female-aphallia-associated-with-severe-urinary-tract-dysplasia
#15
Ariella A Friedman, Paul F Zelkovic, Edward F Reda, Israel Franco, Lane S Palmer
INTRODUCTION: Aphallia is exceedingly rare (1/30 million births). Previous reports have provided limited detail on associated urinary tract findings. OBJECTIVE: We reviewed urinary tract anomalies in two boys with aphallia (patients 1 and 2) and a girl with urinary tract dysplasia, a similar external appearance and lack of corporal tissue (patient 3), also consistent with aphallia. CASE REPORTS (FIGURE): Patients 1 and 2 both had a 46XY karyotype, bilateral descended testes in well-formed scrotums, and posterior skin tags containing rudimentary urethras...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27496467/benign-cutaneous-disease-among-polish-renal-transplant-recipients
#16
B Imko-Walczuk, A Okuniewska, A Prędota-Głowacka, J Jaśkiewicz, W Placek, Z Włodarczyk, A Dębska-Ślizień, B Rutkowski
BACKGROUND: Organ transplant recipients are an at-risk group for skin cancers and benign cutaneous diseases. Immunosuppression type, dosage, and treatment length dictates the frequency of benign lesions. MATERIAL AND METHODS: Two hundred twenty-three consecutive adult renal transplant recipients (RTRs) were enrolled and screened for benign skin lesions. During examination, swabs, skin scrapings, and nail clippings were collected from any suspected areas infection and any cutaneous lesions marked for quality and quantity on a special questionnaire...
June 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27486796/live-cell-bioorthogonal-chemical-imaging-stimulated-raman-scattering-microscopy-of-vibrational-probes
#17
Lu Wei, Fanghao Hu, Zhixing Chen, Yihui Shen, Luyuan Zhang, Wei Min
Innovations in light microscopy have tremendously revolutionized the way researchers study biological systems with subcellular resolution. In particular, fluorescence microscopy with the expanding choices of fluorescent probes has provided a comprehensive toolkit to tag and visualize various molecules of interest with exquisite specificity and high sensitivity. Although fluorescence microscopy is currently the method of choice for cellular imaging, it faces fundamental limitations for studying the vast number of small biomolecules...
August 16, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27485780/the-microbiome-of-aseptically-collected-human-breast-tissue-in-benign-and-malignant-disease
#18
Tina J Hieken, Jun Chen, Tanya L Hoskin, Marina Walther-Antonio, Stephen Johnson, Sheri Ramaker, Jian Xiao, Derek C Radisky, Keith L Knutson, Krishna R Kalari, Janet Z Yao, Larry M Baddour, Nicholas Chia, Amy C Degnim
Globally breast cancer is the leading cause of cancer death among women. The breast consists of epithelium, stroma and a mucosal immune system that make up a complex microenvironment. Growing awareness of the role of microbes in the microenvironment recently has led to a series of findings important for human health. The microbiome has been implicated in cancer development and progression at a variety of body sites including stomach, colon, liver, lung, and skin. In this study, we assessed breast tissue microbial signatures in intraoperatively obtained samples using 16S rDNA hypervariable tag sequencing...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27441553/the-dermis-as-a-delivery-site-of-trypanosoma-brucei-for-tsetse-flies
#19
Guy Caljon, Nick Van Reet, Carl De Trez, Marjorie Vermeersch, David Pérez-Morga, Jan Van Den Abbeele
Tsetse flies are the sole vectors of Trypanosoma brucei parasites that cause sleeping sickness. Our knowledge on the early interface between the infective metacyclic forms and the mammalian host skin is currently highly limited. Glossina morsitans flies infected with fluorescently tagged T. brucei parasites were used in this study to initiate natural infections in mice. Metacyclic trypanosomes were found to be highly infectious through the intradermal route in sharp contrast with blood stream form trypanosomes...
July 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27416624/-impact-of-low-level-laser-therapy-on-skin-blood-flow
#20
Jacek Podogrodzki, Michał Lebiedowski, Mieczysław Szalecki, Izabela Kępa, Małgorzata Syczewska, Sergiusz Jóźwiak
UNLABELLED: The aim of this study was to objectively assess the impact of low level laser therapy on skin blood flow, in terms of two of its components - the flow and trophic and therapeutic effect. MATERIAL AND METHODS: Nineteen children aged 3-15 years have been included in the study (seven boys and twelve girls) with a diagnosis of meningomyelocele in the lumbosacral area. In nine of them (47.3%) bedsores were found in the area of paresis location. Studies of skin blood flow were performed using xenon 133 clearance in the Department of Nuclear Medicine of the Children's Memorial Health Institute...
January 2016: Developmental Period Medicine
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