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https://www.readbyqxmd.com/read/29134108/host-and-bacterial-proteases-influence-biofilm-formation-and-virulence-in-a-murine-model-of-enterococcal-catheter-associated-urinary-tract-infection
#1
Wei Xu, Ana L Flores-Mireles, Zachary T Cusumano, Enzo Takagi, Scott J Hultgren, Michael G Caparon
Enterococcus faecalis is a leading causative agent of catheter-associated urinary tract infection (CAUTI), the most common hospital-acquired infection. Its ability to grow and form catheter biofilm is dependent upon host fibrinogen (Fg). Examined here are how bacterial and host proteases interact with Fg and contribute to virulence. Analysis of mutants affecting the two major secreted proteases of E. faecalis OG1RF (GelE, SprE) revealed that while the loss of either had no effect on virulence in a murine CAUTI model or for formation of Fg-dependent biofilm in urine, the loss of both resulted in CAUTI attenuation and defective biofilm formation...
2017: NPJ Biofilms and Microbiomes
https://www.readbyqxmd.com/read/29124521/successful-peritoneal-dialysis-using-a-percutaneous-tube-for-peritoneal-drainage-in-an-extremely-low-birth-weight-infant-a-case-report
#2
Satoshi Yokoyama, Takayuki Nukada, Yuka Ikeda, Shigeto Hara, Akira Yoshida
BACKGROUND: Peritoneal dialysis (PD) for acute kidney injury (AKI) of newborns has been performed safely. AKI occurs in 8 to 24% of extremely low birth weight (ELBW) infants. Although PD has only been used occasionally in ELBW infants, prognosis is poor for ELBW infants with AKI. Several reports have described successful PD in these infants, but no guideline-based evidence concerning indications for renal replacement therapy in ELBW infants are currently available. Here, we report on our experience with PD in an ELBW infant with AKI resulting from septic shock...
November 9, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29118543/laser-induced-synlabia-cryptomenorrhea-and-urine-retention-a-case-report-and-literature-review
#3
Thoraya Fadul-Elahi, Nusrat Batool Janjua
Cosmetic laser use has many pros and cons. The worldwide use of laser for body hair removal has led to many medical complications. Unsupervised use of the laser for hair removal in vulva may result in many problems and can merely damage the vulva, although rarely, affecting the body image. This rare and novel case report is a 21 year old virgin who presented with acute urinary retention and cryptomenorrhea due to complete synlabia secondary to unsupervised vulval laser hair removal. The urinary retention was relieved by suprapubic catheterization initially...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29115369/useful-independent-factors-for-distinguish-infection-and-colonization-in-patients-with-urinary-carbapenemase-producing-enterobacteriaceae-isolation
#4
L López-González, F J Candel, J M Viñuela-Prieto, J González-Del Castillo, A B García, I Pena, I Rodríguez-Avial
OBJECTIVE: The aim of this study is to know epidemiologic and clinical differences among those patients colonized or infected by carbapenemase-producing Enterobacteriaceae (CPE) and develop a predictive model to facilitate the clinical approach concerning to start antimicrobial therapy. METHODS: Observational retrospective cohort study was performed involving all patients with Urine carbapenemase-producing Enterobacteriaceae isolation (UCPEI) between November 2013 and July 2015...
November 7, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/29105596/ureteral-reconstruction-in-goats-using-tissue-engineered-templates-and-subcutaneous-pre-implantation
#5
Paul K J D de Jonge, Marije Sloff, Heinz Peter Janke, Luuk R M Versteegden, Barbara B Kortmann, Robert P E de Gier, Paul J Geutjes, Egbert Oosterwijk, Wout Feitz
INTRODUCTION: Repair of long ureteral defects often requires long graft tissues and extensive surgery. This is associated with complications including a lack of suitable tissue and graft site morbidity. Tissue engineering may provide an attractive alternative to the autologous graft tissues. In this study, ureteral repair using (pre-implanted) tubular collagen-Vicryl templates was evaluated in a new goat model. MATERIALS AND METHODS: Tubular templates were prepared from tubularized Vicryl meshes and 0...
November 4, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29104788/comparison-of-tamsulosin-and-silodosin-in-the-management-of-acute-urinary-retention-secondary-to-benign-prostatic-hyperplasia-in-patients-planned-for-trial-without-catheter-a-prospective-randomized-study
#6
Siddangouda B Patil, Kshitiz Ranka, Vinay S Kundargi, Nilesh Guru
Introduction: We present a prospective randomized study to compare the efficacy of tamsulosin and silodosin in patients suffering from acute urinary retention caused by benign prostatic hyperplasia, planned for trial without catheter. Material and methods: Patients with acute urinary retention secondary to benign prostatic hyperplasia (total 160) were catheterized and randomized into two groups: Group A: tamsulosin 0.4 mg (80 patients) and Group B: silodosin 8 mg (80 patients)...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29099378/-prognostic-factors-predicting-failure-of-the-trial-without-catheter-after-tamsulosin-in-patients-with-acute-urinary-retention
#7
Oscar Luis Farelo-Trejos, Nahuel Eduardo Paesano, Juan José Serna-Hurtado, Mauro Fabián García, Juan Ignacio Monzó-Gardiner
OBJECTIVE: To analyze prognostic variables that impact on the trial without catheter after tamsulosin in patients with acute urine retention. METHODS: Retrospective analysis of a prospective database of a cohort of successive patients with acute urinary retention due to benign prostatic hyperplasia attended at the urology emergency room during one year time period. We analyzed the clinical and radiological characteristics and the international prostatic symptom score questionnaire of a total 65 male patients...
November 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29098196/perirenal-abscess-after-partial-nephrectomy-because-of-migration-of-upper-calix-stone-and-urine-leakage-a-case-report
#8
Sheng-Chun Hung, Li-Wen Chang, Cheng-Kuang Yang
Background: Nephron-sparing surgery has been shown to achieve oncological results equivalent to those of radical nephrectomy in patients with compromised renal function who have renal tumors <4 cm. However, technical difficulties and potential surgical complications remain challenges to the surgeon. Various factors, such as tumor size and location, collecting system invasion, and patient's expectations, are major concerns that may affect the feasibility of performing an effective partial nephrectomy. We report a patient with renal cell carcinoma who underwent open partial nephrectomy and suffered from complications of perirenal abscess because of stone migration, obstruction, and subsequence urine leakage...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29098192/forgotten-perinephric-drain-anchored-in-the-tissues-lessons-to-be-learned
#9
Prashant Kumar, Rishi Nayyar
Background: Drainage of any deep seated abscess often requires placement of catheters along with other conservative measures. These catheters are removed when the drainage volume reduces to clinically insignificant levels. However, if left in situ, there are potential complications. One such complication necessitating additional surgical procedure is highlighted in this case report. Malecot's catheter and children may be more at risk for such a complication. Case Presentation: A 7-year-old girl presented with recurrent episodes of right flank pain associated with high-grade fever with chills for the last 5 months and right perinephric drain in situ...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29080620/comparison-of-hypotensive-diuretic-and-renal-effects-between-cladodes-of-opuntia-ficus-indica-and-furosemide
#10
Meryem Bakour, Noori Al-Waili, Redouan El-Haskoury, Nawal El-Menyiy, Thia Al-Waili, Ali Al-Waili, Badiaa Lyoussi
OBJECTIVE: To investigate the diuretic, hypotensive and renal effect of Opuntia ficus-indica in two different species in oral and intravenous administration. METHODS: Diuretic activity was evaluated in rats with the plant cladode gel and aqueous extract administrated orally, and was evaluated in rabbits with plant extract administered intravenously. Single and repeated doses of cladode gel or aqueous extract of cladode were tested. Urine volume and blood and urine creatinine, sodium and potassium were measured, and creatinine clearance was calculated...
September 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29072566/does-cranberry-have-a-role-in-catheter-associated-urinary-tract-infections
#11
Dominique Thomas, Matthew Rutman, Kimberly Cooper, Andrew Abrams, Julia Finkelstein, Bilal Chughtai
INTRODUCTION: Catheter-associated urinary tract infections (CA-UTIs) are a prevalent and costly condition, with very few therapeutic options. We sought to evaluate the efficacy of an oral cranberry supplement on catheter-associated urinary tracts infections over a six-month period. METHODS: Subjects with long-term indwelling catheters and recurrent symptomatic CA-UTIs were enrolled to take a once-daily cranberry supplement - an oral cranberry supplement with 36 mg of the active ingredient proanthocyanidin (PACs)...
November 11, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29071162/evaluation-of-the-risk-factors-associated-with-the-development-of-post-transurethral-resection-of-the-prostate-persistent-bacteriuria
#12
Tarek Osman, Karim Omar ElSaeed, Hassan A Youssef, Mohamed Shabayek, Ahmed Emam, Mohammed Saad Hussein
OBJECTIVES: To determine the preoperative, intraoperative and postoperative risk factors that influence the development of persistent post-transurethral resection of the prostate (TURP) urinary tract infection (UTI) defined as pyuria and/or bacteriuria remaining for 3 weeks after surgery. PATIENTS AND METHODS: This is a prospective study including 100 patients scheduled for TURP. Urine analysis and culture was performed immediately after catheter removal, then at 1 and 3 weeks postoperatively, and the results were correlated to various preoperative, intraoperative and postoperative potential risk factors to detect any significant relation to persistent UTI...
September 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29053886/a-historical-perspective-and-evolution-of-the-treatment-of-male-urinary-incontinence
#13
Julio T Chong, Vannita Simma-Chiang
AIMS: To describe the historical changes from antiquity until present in the presentation and treatment of male urinary incontinence. METHODS: A literature review of PubMed articles in English pertaining to male incontinence was performed. RESULTS: Male urinary incontinence was first mentioned in Egyptian manuscripts in 1500 B.C. In 1564, Ambroise Pare designed portable urinals for incontinent males. Wilhem Hildanus created the first condom catheter with pig bladder in the 1600s and was also credited with fashioning the first penile clamp...
October 20, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29043532/changes-observed-in-urine-microbiology-following-replacement-of-long-term-urinary-catheters-need-to-modify-uti-guidelines-in-the-uk
#14
Deepak Batura, G Gopal Rao, Marion Foran, Fatmata Brempong
AIMS: Bacteria adherent to long-term urinary catheters (LTUC) may give misleading urine culture results. Guidelines in the USA recommend changing LTUC before urine collection to diagnose UTI and before commencing appropriate antimicrobial treatment. However, in the UK there is no such guidance. In this study, we evaluated differences in urine cultures before and after changing LTUC. METHODS: In a prospective study in a UK urology department, we made a quantitative and qualitative comparison between paired urines collected before and after catheter change in patients with LTUC...
October 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29024820/coating-of-silicone-with-mannoside-pamam-dendrimers-to-enhance-formation-of-non-pathogenic-escherichia-coli-biofilms-against-colonization-of-uropathogens
#15
Zhiling Zhu, Fei Yu, Haoqing Chen, Jun Wang, Analette I Lopez, Quan Chen, Siheng Li, Yuyu Long, Rabih O Darouiche, Richard A Hull, Lijuan Zhang, Chengzhi Cai
Bacterial interference using non-pathogenic Escherichia coli 83972 is a novel strategy for preventing catheter-associated urinary tract infection (CAUTI). Crucial to the success of this strategy is to establish a high coverage and stable biofilm of the non-pathogenic bacteria on the catheter surface. However, this non-pathogenic strain is sluggish to form biofilms on silicone as the most widely used material for urinary catheters. We have addressed this issue by modifying the silicone catheter surfaces with mannosides that promote the biofilm formation, but the stability of the non-pathogenic biofilms challenged by uropathogens over long-term remains a concern...
December 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29023188/preliminary-experience-with-instillation-of-triamcinolone-acetonide-into-the-urethra-for-idiopathic-urethritis-a-prospective-pilot-study
#16
Junaid Ashraf, Anna R Radford, Alexander Turner, Ramnath Subramaniam
BACKGROUND: Idiopathic bulbar urethritis (IBU) is characterized by hematuria ± dysuria without infection. Symptoms result from inflammation of the bulbar urethra, distal to external sphincter. IBU is difficult to manage and there is no recommended therapy. OBJECTIVE: To determine whether instillation of triamcinolone acetonide is a useful treatment of IBU and its associated complications. SETTING AND PARTICIPANTS: Data were prospectively collected, for 22 months, on 14 consecutive patients presenting with terminal hematuria or blood spotting ± dysuria to a pediatric urology unit...
November 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29021656/a-randomized-controlled-study-comparing-the-standard-tubeless-and-totally-tubeless-percutaneous-nephrolithotomy-procedures-for-renal-stones-from-a-tertiary-care-hospital
#17
Suresh Bhat, Jithin Lal, Fredrick Paul
INTRODUCTION: Percutaneous nephrolithotomy (PCNL) is an effective treatment for renal stones. Due to the significant pain and morbidity after standard PCNL because of nephrostomy tubes, various modifications of PCNL are being performed. We report a randomized trial comparing these modalities. MATERIALS AND METHODS: A total of 75 patients were randomized into three groups of 25 each: standard PCNL with nephrostomy tubes (Group 1), tubeless PCNL with ureteric stent and no nephrostomy (Group 2), and totally tubeless PCNL without ureteric catheter or nephrostomy (Group 3)...
October 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28986400/preoperative-selective-vs-non-selective-%C3%AE-blockade-in-ppgl-patients-undergoing-adrenalectomy
#18
Caojie Liu, Qingguo Lv, Xinlei Chen, Guangcheng Ni, Liru Hu, Yuwei Zhang, Nanwei Tong
PURPOSE: Preoperative preparation for adrenalectomy for pheochromocytomas and paragangliomas (PPGL) is universally recognized as necessary, while the optimal strategy remains controversial. Our aims were to increase intraoperative hemodynamic stability, expedite postoperative recovery, decrease side effects and reduce costs for patients with PPGL undergoing adrenalectomy. METHODS: We identified 526 patients undergoing open adrenalectomy for PPGL in the West China Hospital of Sichuan University between May, 2007 and December, 2016...
November 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28973965/biofilm-formation-by-uropathogenic-escherichia-coli-is-favored-under-oxygen-conditions-that-mimic-the-bladder-environment
#19
Allison R Eberly, Kyle A Floyd, Connor J Beebout, Spencer J Colling, Madison J Fitzgerald, Charles W Stratton, Jonathan E Schmitz, Maria Hadjifrangiskou
One of the most common urologic problems afflicting millions of people worldwide is urinary tract infection (UTI). The severity of UTIs ranges from asymptomatic bacteriuria to acute cystitis, and in severe cases, pyelonephritis and urosepsis. The primary cause of UTIs is uropathogenic Escherichia coli (UPEC), for which current antibiotic therapies often fail. UPEC forms multicellular communities known as biofilms on urinary catheters, as well as on and within bladder epithelial cells. Biofilm formation protects UPEC from environmental conditions, antimicrobial therapy, and the host immune system...
September 30, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28970961/microorganisms-identified-in-the-maternal-bladder-discovery-of-the-maternal-bladder-microbiota
#20
Kristin M Jacobs, Krystal J Thomas-White, Evann E Hilt, Alan J Wolfe, Thaddeus P Waters
Objective  The objective of this study was to characterize the bladder microbiota in pregnancy. Methods  A prospective observational study of 51 pregnant women, admitted to a tertiary care hospital, who underwent straight catheterization urine collection or transurethral Foley catheter placement. 16S rRNA gene sequencing and enhanced quantitative urine culture assessed the maternal bladder microbiota with comparisons made to standard urine culture results. Results  Enhanced quantitative urine culture and 16S rRNA gene sequencing detected bacteria in the majority of participants...
July 2017: American Journal of Perinatology Reports
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