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https://www.readbyqxmd.com/read/28220601/multiple-sclerosis-and-nephrolithiasis-a-matched-case-comparative-study
#1
Vishnu Ganesan, Wen Min Chen, Rajat Jain, Shubha De, Manoj Monga
OBJECTIVE: To compare stone composition and serum/urine biochemistries in stone formers with multiple sclerosis (MS) against stone formers without MS and to examine the association between mobility, methods of bladder emptying, and stone formation. MATERIALS AND METHODS: In this retrospective case-control study, we identified patients diagnosed with multiple sclerosis and kidney stone disease who were seen at our institution between 2001 and 2016. For the first part of the study, up to 2 controls (stone formers without a history of MS) were identified for each case and matched on age, body mass index (BMI), and sex...
February 20, 2017: BJU International
https://www.readbyqxmd.com/read/28220407/favourable-outcome-in-two-pregnancies-in-a-patient-with-3-hydroxy-3-methylglutaryl-coa-lyase-deficiency
#2
David Santosa, Markus G Donner, Stephan Vom Dahl, Markus Fleisch, Thomas Hoehn, Ertan Mayatepek, Katrin Heldt, Tim Niehues, Dieter Häussinger
In patients with 3-hydroxy-3-methylglutaryl(HMG)-CoA lyase deficiency (OMIM 246450), five pregnancies have been described worldwide, which were either terminated or resulted in severe metabolic sequelae during pregnancy or delivery. Here, we report on a patient with HMG-CoA lyase deficiency, who underwent two uncomplicated pregnancies. The 19-year-old patient was admitted because of recurrent vomiting and nausea. Diagnostics revealed pregnancy at week 8 of gestation. Metabolic analyses revealed normal lactate and blood glucose levels and normal acid-base status...
February 21, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28190700/epidemiology-of-escherichia-coli-bacteraemia-in-england-results-of-an-enhanced-sentinel-surveillance-programme
#3
J Abernethy, R Guy, E A Sheridan, S Hopkins, M Kiernan, M H Wilcox, A P Johnson, R Hope
BACKGROUND: Escherichia coli causes more than one-third of the bacteraemia cases in England each year, and the incidence of these infections is increasing. AIM: To determine the underlying risk factors associated with E. coli bacteraemia. METHODS: A three-month enhanced sentinel surveillance study involving 35 National Health Service hospitals was undertaken in the winter of 2012/13 to collect risk factor information and further details on the underlying source of infection to augment data already collected by the English national surveillance programme...
December 16, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28188050/successful-treatment-with-caspofungin-of-candiduria-in-a-child-with-wilms-tumor-review-of-literature
#4
M S Rezai, A Vaezi, H Fakhim, A Soleimani, H Mohammad Jafari, S Mohseni, H Badali
Symptomatic candiduria often occurs in patients with indwelling bladder catheters or immunocompromised host. Isolation of Candida in urine in high-risk patients should primarily be considered as a marker for candidemia. Hematological and genitourinary malignancies are one of the main risk factors associated with Candida urinary tract infections (CUTI). Fluconazole is a choice for initial treatment of CUTI, but it is fluctuate depending on the patient's condition including renal failure, site of urinary infection and Candida species...
February 7, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28186928/collecting-biological-material-from-palliative-care-patients-in-the-last-weeks-of-life-a-feasibility-study
#5
Séamus Coyle, Aileen Scott, Amara Callistus Nwosu, Richard Latten, James Wilson, Catriona R Mayland, Stephen Mason, Chris Probert, John Ellershaw
OBJECTIVE: To assess the feasibility of prospectively collecting biological samples (urine) from palliative care patients in the last weeks of life. SETTING: A 30-bedded specialist hospice in the North West of England. PARTICIPANTS: Participants were adults with a diagnosis of advanced disease and able to provide written informed consent. METHOD: Potential participants were identified by a senior clinician over a 12-week period in 2014...
November 10, 2016: BMJ Open
https://www.readbyqxmd.com/read/28183578/a-case-of-central-diabetes-insipidus-after-ketamine-infusion-during-an-external-to-internal-carotid-artery-bypass
#6
Sharib Gaffar, Jonathan P Eskander, Burton D Beakley, Brian P McClure, Peter Amenta, Nakeisha Pierre
STUDY OBJECTIVE: We report the first teenage case of ketamine-induced transient central diabetes insipidus. CASE SUMMARY: The patient was an 18-year-old woman with moyamoya disease undergoing an external carotid to internal carotid bypass and given a low-dose ketamine infusion. After approximately 2 hours in the supine position, with 0.5 Minimum Alveolar Concentration (MAC) of sevoflurane, a propofol infusion at 50 μg/kg/min, a remifentanil infusion at 0.5 μg/kg/min, and a ketamine infusion at a dose of 10 μg/kg/min, this patient had an excessive urine output...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28179199/robotic-cystotomy-for-pessary-extraction-with-vesicovaginal-fistula-repair
#7
Whitney Goldsberry, Daniel S Metzinger
STUDY OBJECTIVE: To demonstrate a robotic approach to foreign body extraction and vesicovaginal fistula repair. DESIGN: Video case presentation with narration discussing the step-by-step robotic surgical approach to the removal of a pessary, via cystotomy, followed by vesicovaginal fistula and cystotomy repair. SETTING: University of Louisville Hospital. The local Institutional Review Board deemed the video exempt from formal approval. PATIENT: A 77-year-old woman presented with complaints of vaginal leakage of urine, dysuria, and pelvic pain...
February 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28178895/repetitive-urine-and-blood-sampling-in-neonatal-and-weaned-piglets-for-pharmacokinetic-and-pharmacodynamic-modelling-in-drug-discovery-a-pilot-study
#8
Elke Gasthuys, Stijn Schauvliege, Thomas van Bergen, Joske Millecam, Ilaria Cerasoli, Ann Martens, Frank Gasthuys, Tim Vandecasteele, Pieter Cornillie, Wim Van den Broeck, Filip Boyen, Siska Croubels, Mathias Devreese
Piglets are considered to be suitable animal models for predicting the pharmacokinetics and pharmacodynamics (PK/PD) of test drugs for potential use in the paediatric population. Such PK/PD studies require multiple blood and urine samplings. The goal of the present study was to determine a suitable blood collection strategy applicable in the youngest age categories of six days, four weeks and eight weeks of age, as well as a urine collection technique for male piglets in the same age categories. Blood was collected either by a surgically-placed jugular vein catheter (six days old [ n = 4] and four weeks old [ n = 2] piglets) or by direct venepuncture of the jugular vein (four weeks old [ n = 2] and eight weeks old [ n = 4] piglets)...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/28178614/geraniol-alleviates-diabetic-cardiac-complications-effect-on-cardiac-ischemia-and-oxidative-stress
#9
Hany M El-Bassossy, Hanna Ghaleb, Ahmed A Elberry, Khadijah S Balamash, Salah A Ghareib, Ahmad Azhar, Zainy Banjar
The present study was planned to assess the possible protective effect of geraniol on cardiovascular complications in an animal model with diabetes. Diabetes was induced in rats by a single streptozotocin injection. In the treated group, geraniol (150mgkg(-1)day(-1)) was administered orally starting from the 15th day after induction of diabetes, and ending after 7 weeks; diabetic control rats were given vehicle for the same period. At the end of the study, cardiac contractility was assessed by using a Millar microtip catheter in anesthetised rats, and cardiac conductivity determined by a surface ECG...
February 5, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28177393/acidogenic-mineral-additions-increased-ca-mobilization-in-prepartum-sows
#10
C Darriet, D E Axe, T D Crenshaw
Increased sow milk production is associated with an increase in unexplained sow mortality during prepartum and early postpartum periods. This association has led to purported claims of hypocalcemic disorders. Assuming similar responses as dairy cows, feeding anionic mineral salts in late gestation and early lactation may reduce potential hypocalcemia related disorders in sows. Two experiments using CAD-MATE (Granco Minerals, Petersburg, VA), an acidogenic mineral supplement (AMS), were designed to determine the amount required to increase urinary Ca excretion and to identify renal compensatory responses to acid loads in sows...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28169451/an-optimized-transurethral-catheterization-cystometry-in-mice-and-comparison-with-classic-suprapubic-catheterization-cystometry
#11
Zhuoyi Xiang, Yaohui Li, Tingchang Bian, Minke He, Yeqing Xu, Guomin Wang, Jianming Guo, Hang Wang
AIMS: The aim of this study is to establish an optimized, minimally invasive transurethral catheterization cystometry (TUCC) and a novel urethral pressure profile (UPP) measurement for mice. METHODS: The optimized TUCC and the UPP measurement were first established. This optimized TUCC was then performed in 16 anesthetized female mice and compared with the suprapubic catheterization cystometry (SCC) in parallel after suprapubic catheters implantation (SCI; on zero, third, and seventh day, respectively)...
February 7, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28150092/antimicrobial-activity-study-of-triclosan-loaded-wbpu-on-proteus-mirabilis-in-vitro
#12
Ye Tian, Zhongyu Jian, Jianzhong Wang, Wei He, Qinyu Liu, Kunjie Wang, Hong Li, Hong Tan
OBJECTIVES: To evaluate the antimicrobial activity study of triclosan-loaded waterborne polyurethanes (WBPU) on Proteus mirabilis in vitro. MATERIALS AND METHODS: Inhibition zone assays on petri plates with triclosan-loaded WBPU samples were used to test its antimicrobial activity on Proteus mirabilis. Models of the catheterized bladder supplied with artificial urine infected with Proteus mirabilis were employed to confirm the antimicrobial activity of triclosan-loaded WBPU...
February 1, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28144131/cranberry-juice-concentrate-does-not-significantly-decrease-the-incidence-of-acquired-bacteriuria-in-female-hip-fracture-patients-receiving-urine-catheter-a-double-blind-randomized-trial
#13
Anna-Karin Gunnarsson, Lena Gunningberg, Sune Larsson, Kenneth B Jonsson
BACKGROUND: Urinary tract infection (UTI) is a common complication among patients with hip fractures. Receiving an indwelling urinary catheter is a risk factor for developing UTIs. Treatment of symptomatic UTIs with antibiotics is expensive and can result in the development of antimicrobial resistance. Cranberries are thought to prevent UTI. There is no previous research on this potential effect in patients with hip fracture who receive urinary catheters. AIM: The aim of this study is to investigate whether intake of cranberry juice concentrate pre-operatively decreases the incidence of postoperative UTIs in hip fracture patients that received a urinary catheter...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28137940/antimicrobial-resistance-in-uropathogens-and-appropriateness-of-empirical-treatment-a-population-based-surveillance-study-in-indonesia
#14
Adhi Kristianto Sugianli, Franciscus Ginting, R Lia Kusumawati, Emmy Hermiyati Pranggono, Ayodhia Pitaloka Pasaribu, Firza Gronthoud, Suzanne Geerlings, Ida Parwati, Menno D De Jong, Frank Van Leth, Constance Schultsz
OBJECTIVES: Urinary tract infections (UTIs) are a common reason for empirical treatment with broad-spectrum antibiotics worldwide. However, population-based antimicrobial resistance (AMR) prevalence data to inform empirical treatment choice are lacking in many regions, because of limited surveillance capacity. We aimed to assess the prevalence of AMR to commonly used antimicrobial drugs in Escherichia coli and Klebsiella pneumoniae isolated from patients with community- or healthcare-associated UTIs on two islands of Indonesia...
January 30, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28131923/does-size-matter-measured-and-modeled-effects-of-suprapubic-catheter-size-on-urinary-flow
#15
Calvin Lee, Bradley C Gill, Sandip Vasavada, Raymond R Rackley
OBJECTIVES: To quantify the effects of catheter size and urinary sediment on catheter drainage, and to determine the French size at which catheter upsizing yields a diminished marginal return in flow. METHODS: Latex Foley catheters (12-26 Fr) were connected to a simulated bladder. Passive drainage times of 450 ml water were measured over 5 successive trials for each catheter size. The effect of sediment was modeled by adding 2g of infant rice cereal to the water...
January 25, 2017: Urology
https://www.readbyqxmd.com/read/28124957/-antimicrobial-susceptibility-and-molecular-characterization-of-multidrug-resistant-acinetobacter-baumannii-isolated-in-an-university-hospital
#16
Şahin Direkel, Ayşegül Çopur Çiçek, Alper Karagöz, Nebahat Aydoğan Ejder, Efdal Oktay, Nuran Delialioğlu, Osman Birol Özgümüş, Rıza Durmaz
Acinetobacter baumannii, an aerobic, non-motile, gram-negative bacterium is an important nosocomial pathogen which shows resistance to the most antibiotics. Carbapenems are the most commonly used antibiotics for the treatment of infections caused by this pathogen. However the emergence of resistance against carbapenems in an increasing rate generates serious problems for antimicrobial therapy. The aims of this study were to detect the antibiotic susceptibility, and the presence of blaOXA resistance genes of clinical A...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28123500/effects-of-low-dose-tolvaptan-on-electrolyte-abnormality-and-hemodynamic-parameters-in-a-liver-cirrhosis-associated-portopulmonary-hypertension-patient-a-case-report
#17
Yoshito Ogihara, Norikazu Yamada, Kaoru Dohi, Akimasa Matsuda, Satoshi Ota, Ken Ishikura, Mashio Nakamura, Masaaki Ito
The present study reported a case of portopulmonary hypertension (POPH) that was secondary to underlying liver cirrhosis in a 58-year-old woman, who was successfully treated with low-dose tolvaptan. The patient had suffered from refractory peripheral edema and electrolyte abnormalities, including severe hypokalemia, under the combination therapy of sildenafil, ambrisentan, furosemide and spironolactone. Subsequent to the initiation of low-dose tolvaptan at 3.75 mg/day with concurrent de-escalation of the dose of furosemide, the daily urine volume increased, peripheral edema improved and the serum potassium level increased immediately...
January 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28122873/rising-stakes-for-healthcare-associated-infection-prevention-implications-for-the-clinical-microbiology-laboratory-revised
#18
Daniel J Diekema
Healthcare associated infection (HAI) rates are subject to public reporting, and are linked to hospital reimbursement from the Centers for Medicare and Medicaid Services (CMS). The increasing pressure to lower HAI rates comes at a time when advances in the clinical microbiology laboratory (CML) provide more precise and sensitive tests, altering HAI detection in ways that may increase reported HAI rates. I review how changing CML practices can impact HAI rates, and how the financial implications of HAI metrics may produce pressure to change diagnostic testing practices...
January 25, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28122140/disorders-of-micturition-in-small-animal-patients-clinical-significance-etiologies-and-management-strategies
#19
Eric Langfitt, Jennifer E Prittie, Yekaterina Buriko, Janine M Calabro
OBJECTIVES: To review the physiology of micturition, the pathophysiology of micturition disorders, and current pharmacological agents used to treat these disorders. To discuss different urinary catheterization techniques, along with the risks of catheter-associated urinary tract infections attributed with these techniques. ETIOLOGY: Many critically ill veterinary patients are at risk of developing a number of neurological and non neurological micturition-related disorders...
January 25, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28117816/a-murine-orthotopic-bladder-tumor-model-and-tumor-detection-system
#20
Sin Mun Tham, Kesavan Esuvaranathan, Ratha Mahendran
This protocol describes the generation of bladder tumors in female C57BL/6J mice using the murine bladder cancer cell line MB49, which has been modified to secrete human Prostate Specific Antigen (PSA), and the procedure for the confirmation of tumor implantation. In brief, mice are anesthetized using injectable drugs and are made to lay in the dorsal position. Urine is vacated from the bladder and 50 µL of poly-L-lysine (PLL) is slowly instilled at a rate of 10 µL/20 s using a 24 G IV catheter. It is left in the bladder for 20 min by stoppering the catheter...
January 12, 2017: Journal of Visualized Experiments: JoVE
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