keyword
MENU ▼
Read by QxMD icon Read
search

Asbergers

keyword
https://www.readbyqxmd.com/read/28718346/effect-of-desvenlafaxine-50-mg-and-100-mg-on-energy-and-lassitude-in-patients-with-major-depressive-disorder-a-pooled-analysis
#1
Raymond W Lam, Dalia B Wajsbrot, Ellen Meier, Elizabeth Pappadopulos, Joan A Mackell, Matthieu Boucher
Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from baseline to endpoint in 17-item Hamilton Rating Scale for Depression (HAM-D17) Work and Activities, Retardation, and Somatic Symptoms General items, HAM-D17 psychomotor retardation factor, and Montgomery-Åsberg Depression Rating Scale Lassitude item were analyzed with a mixed model for repeated measures analysis of variance...
July 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28712841/long-term-impact-of-subthalamic-stimulation-on-cognitive-function-in-patients-with-advanced-parkinson-s-disease
#2
M Acera, A Molano, B Tijero, G Bilbao, I Lambarri, R Villoria, J Somme, E Ruiz de Gopegui, I Gabilondo, J C Gomez-Esteban
OBJECTIVE: The aim of this study was to evaluate the effects of deep brain stimulation of the subthalamic nucleus (DBS-SN) on cognitive function in patients with Parkinson's disease (PD) 5 years after surgery. MATERIAL AND METHODS: We conducted a prospective study including 50 patients with PD who underwent DBS-SN (62.5% were men; mean age of 62.2±8.2 years; mean progression time of 14.1±6.3 years). All patients were assessed before the procedure and at one year after surgery; 40 patients were further followed up until the 5-year mark...
July 13, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28696415/genome-wide-association-studies-of-placebo-and-duloxetine-response-in-major-depressive-disorder
#3
M Maciukiewicz, V S Marshe, A K Tiwari, T M Fonseka, N Freeman, J L Kennedy, S Rotzinger, J A Foster, S H Kennedy, D J Müller
We investigated variants associated with treatment response in depressed patients treated with either the antidepressant duloxetine or placebo using a genome-wide approach. Our sample (N=391) included individuals aged 18-75 years, diagnosed with major depressive disorder and treated with either duloxetine or placebo for up to 8 weeks. We conducted genome-wide associations for treatment response as operationalized by percentage change in Montgomery-Åsberg Depression Rating Scale score from baseline, as well as mixed models analyses across five time points...
July 11, 2017: Pharmacogenomics Journal
https://www.readbyqxmd.com/read/28696022/outcomes-in-pancreas-transplantation-with-exocrine-drainage-through-a-duodenoduodenostomy-versus-duodenojejunostomy
#4
J P Lindahl, R Horneland, E Nordheim, A Hartmann, E M Aandahl, K Grzyb, H Haugaa, G Kjøsen, A Åsberg, T Jenssen
Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access for biopsies. This study assessed safety profiles with DD versus DJ procedures, and clinical outcomes with the DD technique in pancreas transplantation. DD patients (n=117; 62 simultaneous pancreas and kidney [SPKDD ] and 55 pancreas transplantation alone [PTADD ] with median follow-up 2...
July 11, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28689637/measurement-of-flow-of-thought-in-68-patients-monitored-in-post-emergency-outpatient-consultations-role-of-ideational-turmoil-in-the-anxiety-depressive-symptomatology
#5
J Vandevoorde, A Sanchez Valero, E Baudoin, S Kamar, B Chabert, T Baudoin
INTRODUCTION: Rumination, cognitive control deficits, cognitive saturation, and loss of inhibition are the major hypotheses used to explain depressive disorders. A few studies have nevertheless looked at the form of thought. In this study, we will test a double measurement of the number of thoughts and a double measurement of the flow of thought together with their correlation with well-being, mental pain, and depression. MATERIAL AND METHODS: Between May and September 2015, 68 subjects, initially admitted as emergencies for acute anxiety depressive disorders and/or suicide attempts and subsequently monitored as post-emergency outpatients in medico-psychological consultations agreed to complete a set of Visual Analogue Scales measuring their well-being, their mental pain, their estimated number of thoughts and the how agitated these thoughts are estimated to be...
July 6, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28685600/life-weariness-and-suicidal-thoughts-in-late-life-a-national-study-in-sweden
#6
Hanna Tuvesson, A Hellström, L Sjöberg, B-M Sjölund, E Nordell, C Fagerström
OBJECTIVES: This study aimed at investigating the point prevalence of life weariness and suicidal thoughts and their relationship with socio-demographic characteristics in a population of older adults in Sweden. METHOD: Data from 7913 individuals aged 60 years and older were drawn from the Swedish National Study on Aging and Care, a collaborative study in Sweden. Life weariness and suicidal thoughts were measured by one item derived from the Montgomery-Åsberg Depression Rating Scale...
July 7, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28678636/iron-loading-in-hfe-p-c282y-homozygotes-found-by-population-screening-relationships-to-hla-type-and-t-lymphocyte-subsets
#7
Ketil Thorstensen, Mona A Kvitland, Wenche Ø Irgens, Arne Åsberg, Berit Borch-Iohnsen, Torolf Moen, Kristian Hveem
Iron loading in p.C282Y homozygous HFE hemochromatosis subjects is highly variable, and it is unclear what factors cause this variability. Finding such factors could aid in predicting which patients are at highest risk and require closest follow-up. The degree of iron loading has previously been associated with certain HLA-types and with abnormally low CD8 + cell counts in peripheral blood. In 183 Norwegian, p.C282Y homozygotes (104 men, 79 women) originally found through population screening we determined HLA type and measured total T-lymphocytes, CD4 + and CD8 + cells, and compared this with data on iron loading...
July 5, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28677828/vortioxetine-for-depression-in-adults
#8
REVIEW
Markus Koesters, Giovanni Ostuzzi, Giuseppe Guaiana, Johanna Breilmann, Corrado Barbui
BACKGROUND: Major depressive disorder is a common mental disorder affecting a person's mind, behaviour and body. It is expressed as a variety of symptoms and is associated with substantial impairment. Despite a range of pharmacological and non-pharmacological treatment options, there is still room for improvement of the pharmacological treatment of depression in terms of efficacy and tolerability. The latest available antidepressant is vortioxetine. It is assumed that vortioxetine's antidepressant action is related to a direct modulation of serotonergic receptor activity and inhibition of the serotonin transporter...
July 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28670290/sex-differences-in-the-peripheral-immune-system-in-patients-with-depression
#9
Badari Birur, Ellen M Amrock, Richard C Shelton, Li Li
BACKGROUND: Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, the objective was to determine whether depressed females show higher inflammation compared to males in a cross-sectional study. MATERIALS AND METHODS: Two hundred participants were enrolled...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28667888/cognitive-impairment-as-measured-by-the-thinc-integrated-tool-thinc-it-association-with-psychosocial-function-in-major-depressive-disorder
#10
Danielle S Cha, Nicole E Carmona, Mehala Subramaniapillai, Rodrigo B Mansur, Yena Lee, Jae Hon Lee, JungGoo Lee, Joshua D Rosenblat, Margarita Shekotikhina, Caroline Park, Carola Rong, Tracy L Greer, Raymond Lam, Bernhard T Baune, John Harrison, Roger S McIntyre
BACKGROUND: Psychosocial impairment represents an important treatment target in major depressive disorder (MDD). The majority of patients with MDD do not regain premorbid levels of psychosocial functioning despite the resolution of core depressive symptoms. This study aimed to investigate the respective effects of cognitive function and depression severity on impaired psychosocial function in MDD. METHODS: Adults aged 18-65 with moderate-to-severe MDD (n = 100) and age-, sex-, and education-matched healthy controls participated in a cross-sectional study validating the THINC-integrated tool (THINC-it), a cognitive screening tool comprised of objective and subjective measures of cognitive function...
June 23, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28667664/tacrolimus-and-mycophenolate-regimen-and-subclinical-tubulo-interstitial-inflammation-in-low-immunological-risk-renal-transplants
#11
Irina B Torres, Anna V Reisaeter, Francesc Moreso, Anders Åsberg, Marta Vidal, Clara Garcia-Carro, Karsten Midtvedt, Finn P Reinholt, Helge Scott, Eva Castellà, Maite Salcedo, Christina Dörje, Joana Sellarés, Maria A Azancot, Manel Perello, Hallvard Holdaas, Daniel Serón
The aim was to evaluate the relationship between maintenance immunosuppression, subclinical tubulo-interstital inflammation and interstitial fibrosis/tubular atrophy (IF/TA) in surveillance biopsies performed in low immunological risk renal transplants at two transplant centers. The Barcelona cohort consisted of 109 early and 66 late biopsies in patients receiving high tacrolimus (TAC-C0 target at 1-year 6-10 ng/mL) and reduced MMF dose (500 mg bid at 1-year). The Oslo cohort consisted of 262 early and 237 late biopsies performed in patients treated with low TAC-C0 (target 3-7 ng/mL) and standard MMF dose (750 mg bid)...
July 1, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28657697/vascular-risk-factors-in-older-patients-with-depression-outcome-of-electroconvulsive-therapy-versus-medication
#12
Harm-Pieter Spaans, Rob M Kok, Filip Bouckaert, Julia F Van Den Berg, Orlaith C Tunney, Pascal Sienaert, Esmée Verwijk, King H Kho, Max L Stek
OBJECTIVE: Research suggests that in depression, vascular burden predicts a lower efficacy for medication (MED) and a more favourable outcome for electroconvulsive therapy (ECT). Therefore, we investigated the influence of the following vascular risk factors (VRF): hypercholesterolemia, hypertension, smoking, diabetes mellitus, cardiovascular disease, and cerebral vascular accident/transient ischemic attack, on remission from major depression after ECT versus MED. METHODS: The study sample consisted of 81 inpatients with a DSM-IV unipolar major depression diagnosis (mean age 72...
June 28, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28657644/communication-in-children-and-adolescents-after-acquired-brain-injury-an-exploratory-study
#13
Åsa Fyrberg, Göran Horneman, Jakob Åsberg Johnels, Gunilla Thunberg, Elisabeth Ahlsén
OBJECTIVE: The usability of the Communicative Effectiveness Index (CETI) in adolescents with acquired brain injury was investigated and compared with linguistic, cognitive and brain injury data. DESIGN: A prospective, longitudinal, between-group design. SUBJECTS: Thirty participants were divided into 2 subgroups: CETI+ and CETI- groups. METHODS: Parental CETI ratings of daily communication were compared with linguistic data and IQ test results...
June 28, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28652746/association-between-serotonin-transporter-polymorphisms-5-httlpr-and-the-madrs-dysphoria-retardation-and-vegetative-subscale-scores-in-the-treatment-of-depression
#14
Hitoshi Takahashi, Hisashi Higuchi, Kazuhiro Sato, Mitsuhiro Kamata, Keizo Yoshida, Katsuji Nishimura
OBJECTIVE: We investigated the association between serotonin- or 5-hydroxytryptamine (5-HT)-related gene polymorphisms and response to antidepressant treatment in a specific symptom cluster of major depression by using the three-factor model of the Montgomery-Åsberg Depression Rating Scale (MADRS), ie, dysphoria (items of sadness, pessimistic thoughts, and suicidal thoughts), retardation (items of lassitude, inability to feel, apparent sadness, and concentration difficulties), and vegetative symptoms (items of reduced sleep, reduced appetite, and inner tension)...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28638206/effect-of-repetitive-transcranial-magnetic-stimulation-on-cigarette-smoking-in-patients-with-schizophrenia
#15
Wanli Huang, Fang Shen, Jiangtao Zhang, Baoping Xing
BACKGROUND: The high smoking rate among patients with schizophrenia is an important public health problem, and researchers have been studying how to change the status quo. OBJECTIVE: We investigated the effects of high frequency (10Hz) repetitive transcranial magnetic stimulation on the amount of cigarette smoking in patients with schizophrenia. METHOD: This study enrolled 37 male patients with schizophrenia who were at a stable stage of treatment...
December 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28636896/early-maladaptive-schemas-of-emotional-deprivation-social-isolation-shame-and-abandonment-are-related-to-a-history-of-suicide-attempts-among-patients-with-major-depressive-disorders
#16
Mohammad Ahmadpanah, Sommayyeh Astinsadaf, Amineh Akhondi, Mohammad Haghighi, Dena Sadeghi Bahmani, Marzieh Nazaribadie, Leila Jahangard, Edith Holsboer-Trachsler, Serge Brand
BACKGROUND: Patients with psychiatric disorders have an exceptionally high risk of completed or attempted suicide. This holds particularly true for patients with major depressive disorders. The aim of the present study was to explore whether patients with major depressive disorders (MDD) and a history of suicide attempts differed in their early maladaptive schemas from patients with MDD but without such a history or from healthy controls. METHOD: Ninety participants took part in the study...
August 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28636572/mood-symptoms-in-stabilized-patients-with-schizophrenia-a-bipolar-type-with-predominant-psychotic-features
#17
Konstantinos N Fountoulakis, Dina Popovic, Mariela Mosheva, Melina Siamouli, Katerina Moutou, Xenia Gonda
BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BD) are traditionally distinguished on the basis of progressive deterioration and long-term outcome, but a more dimensional approach is warranted. There are limited data on the occurrence of manic symptoms in patients with schizophrenia. The aim of the current study was to search for patterns in the clinical symptomatology, which may suggest the presence of one or several mood disorders under the label of schizophrenia. SUBJECTS AND METHODS: Hundred-seventy-five patients diagnosed with schizophrenia according to DSM-5 were included in the study...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28632428/clinical-and-socio-demographic-correlates-of-anxious-distress-in-asian-outpatients-with-major-depressive-disorder
#18
Narong Maneeton, Sirijit Suttajit, Benchalak Maneeton, Surinporn Likhitsathian, Kanokkwan Eurviyanukul, Pichet Udomratn, Edwin Shih-Yen Chan, Tian-Mei Si, Ahmad Hatim Sulaiman, Chia-Hui Chen, Dianne Bautista, Manit Srisurapanont
BACKGROUND: Anxious distress in major depressive disorder (MDD) is common and associated with poor outcomes and management difficulties. AIMS: This post hoc analysis aimed to examine the socio-demographic and clinical correlates of anxiety distress in Asian outpatients with MDD. METHODS: Instead of two out of five specifiers defined by the Diagnostic and Statistical Manual Version-5, anxious distress defined in this study was operationalized as the presence of at least two out of four proxy items drawn from the 90-item Symptom Checklist, Revised (SCL-90-R)...
June 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28631695/-chronic-stress-and-mental-disorders-in-patients-with-systemic-scleroderma-results-of-an-interdisciplinary-study
#19
O F Seravina, T A Lisitsyna, M N Starovoytova, O V Desinova, O B Kovalevskaya, D Yu Veltishchev
AIM: To analyze of the prevalence of stressful factors and mental disorders (MDs), as well as their clinical psychopathological and clinical psychological characteristics to improve the comprehensive diagnosis and treatment of systemic scleroderma (SSD). SUBJECTS AND METHODS: Examinations were performed in 110 patients (predominantly women (n=97 (88.2%); mean age, 49.9±2.47 years) with a documented diagnosis of SSD (its mean duration, 7.25±0.42 years). 62 (56...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28628806/resilience-and-spirituality-in-patients-with-depression-and-their-family-members-a-cross-sectional-study
#20
Chisa Ozawa, Takefumi Suzuki, Yuya Mizuno, Ryosuke Tarumi, Kazunari Yoshida, Kazuhito Fujii, Jinichi Hirano, Hideaki Tani, Ellen B Rubinstein, Masaru Mimura, Hiroyuki Uchida
OBJECTIVE: The degree and quality of resilience in patients with depression have never been investigated in the context of remission status, spirituality/religiosity, and family members' resilience levels, which was addressed in this study. METHODS: This cross-sectional study recruited Japanese outpatients with depressive disorder according to ICD-10 and cohabitant family members who were free from psychiatric diagnoses. Resilience was assessed using the 25-item Resilience Scale (RS)...
June 8, 2017: Comprehensive Psychiatry
keyword
keyword
111401
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"