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https://www.readbyqxmd.com/read/29346608/on-demand-intraoperative-3-dimensional-printing-of-custom-cranioplastic-prostheses
#1
Alexander I Evins, John Dutton, Sayem S Imam, Amal O Dadi, Tao Xu, Du Cheng, Philip E Stieg, Antonio Bernardo
BACKGROUND: Currently, implantation of patient-specific cranial prostheses requires reoperation after a period for design and formulation by a third-party manufacturer. Recently, 3-dimensional (3D) printing via fused deposition modeling has demonstrated increased ease of use, rapid production time, and significantly reduced costs, enabling expanded potential for surgical application. Three-dimensional printing may allow neurosurgeons to remove bone, perform a rapid intraoperative scan of the opening, and 3D print custom cranioplastic prostheses during the remainder of the procedure...
January 13, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29346300/trapezium-bone-density-a-comparison-of-measurements-by-dxa-and-ct
#2
Sebastian Breddam Mosegaard, Kamille Breddam Mosegaard, Nadia Bouteldja, Torben Bæk Hansen, Maiken Stilling
Bone density may influence the primary fixation of cementless implants, and poor bone density may increase the risk of implant failure. Before deciding on using total joint replacement as treatment in osteoarthritis of the trapeziometacarpal joint, it is valuable to determine the trapezium bone density. The aim of this study was to: (1) determine the correlation between measurements of bone mineral density of the trapezium obtained by dual-energy X-ray absorptiometry (DXA) scans by a circumference method and a new inner-ellipse method; and (2) to compare those to measurements of bone density obtained by computerized tomography (CT)-scans in Hounsfield units (HU)...
January 18, 2018: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29346243/pars-plana-vitrectomy-with-anterior-chamber-versus-gore-tex-sutured-posterior-chamber-intraocular-lens-placement-long-term-outcomes
#3
M Ali Khan, Omesh P Gupta, Kasim Pendi, Allen Chiang, James Vander, Carl D Regillo, Jason Hsu
PURPOSE: To compare clinical outcomes of combined pars plana vitrectomy (PPV) with anterior chamber intraocular lens (ACIOL) placement versus scleral fixation of a posterior chamber intraocular lens (PCIOL) using Gore-Tex suture. METHODS: Retrospective, interventional case series of eyes undergoing combined PPV and IOL placement for retained lens material, aphakia, or dislocated IOL. Eyes with history of amblyopia, corneal opacity, retinal, or optic nerve disease were excluded...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29346095/feature-map-quality-score-estimation-through-regression
#4
Ibrahim M H Rahman, Christopher Hollitt, Mengjie Zhang
Understanding the visual quality of a feature map plays a significant role in many active vision applications. Previous works mostly rely on object-level features, such as compactness, to estimate the quality score of a feature map. However, the compactness is leveraged on feature maps produced by salient object detection techniques where the maps tend to be compact. As a result, the compactness feature fails when the feature maps are blurry (e.g., fixation maps). In this paper, we regard the process of estimating the quality score of feature maps, specifically fixation maps, as a regression problem...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29345115/metatranscriptome-analysis-reveals-environmental-and-diel-regulation-of-a-heterosigma-akashiwo-raphidophyceae-bloom
#5
Nanjing Ji, Lingxiao Lin, Ling Li, Liying Yu, Yaqun Zhang, Hao Luo, Meizhen Li, Xinguo Shi, Da-Zhi Wang, Senjie Lin
Despite numerous laboratory studies on physiologies of harmful algal bloom (HAB) species, physiologies of these algae during a natural bloom are understudied. Here, we investigated a bloom of the raphidophyte Heterosigma akashiwo in the East China Sea in 2014 using metabarcode (18S rDNA) and metatranscriptome sequencing. Based on 18S rDNA analyses, the phytoplankton community shifted from high diversity in the pre-bloom stage to H. akashiwo predominance during the bloom. A sharp decrease in ambient dissolved inorganic phosphate and strong up-regulation of phosphate and dissolved organic phosphorus (DOP) uptake genes, including the rarely documented (ppGpp)ase, in H...
January 18, 2018: Environmental Microbiology
https://www.readbyqxmd.com/read/29344904/mgmt-assessment-in-pituitary-adenomas-comparison-of-different-immunohistochemistry-fixation-chemicals
#6
Alexander S G Micko, Romana Höftberger, Adelheid Wöhrer, Matthias Millesi, Engelbert Knosp, Stefan Wolfsberger
PURPOSE: Despite the established role of O6-methyl-guanine-DNA methyltransferase (MGMT) as a marker for temozolomide response, consensus of the most reliable method to assess MGMT expression in pituitary adenomas is still missing. Currently, immunohistochemistry (IHC) assessment of formaldehyde fixed tissue samples is most widely used in a semiquantitative description. As formaldehyde fails to completely preserve nucleic acids, RCL2, an alcohol-based formaldehyde-free fixative, has been proposed as a more reliable alternative in terms of cell stability...
January 17, 2018: Pituitary
https://www.readbyqxmd.com/read/29344873/laser-capture-microdissection-and-rna-extraction-from-perfusion-fixed-cartilage-and-bone-tissue-from-mice-implanted-with-human-ipsc-derived-mscs-in-a-calvarial-defect-model
#7
Xiaonan Xin, Xi Jiang, Alexander Lichtler, Mark Kronenberg, David Rowe, Joel S Pachter
Laser-capture microdissection (LCM) coupled to downstream RNA analysis poses unique difficulties for the evaluation of mineralized tissues. A rapid protocol was thus developed to enable sufficient integrity of bone and cartilage tissue for reliable sectioning, while minimizing RNA loss associated with prolonged decalcification and purification steps. Specifically, the protocol involves pump-assisted, cardiac perfusion-fixation with paraformaldehyde, and moderate digestion of LCM-acquired tissue with proteinase K followed by DNase treatment and separation of RNA using magnetic beads...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344861/laser-capture-microdissection-and-transcriptional-analysis-of-sub-populations-of-the-osteoblast-lineage-from-undecalcified-bone
#8
Efrain Pacheco, Rong Hu, Scott Taylor
Transcriptional analysis of tissue samples is a useful and widely applied approach to provide insight into the molecular mechanisms engaged in response to phenotypic changes or external stimuli. We describe a method that overcomes the technical challenges associated with the application of Laser Capture Microdissection to undecalcified bone enabling us to collect high-quality bone tissue with maintained cellular morphology that is suitable for cryosectioning, fixation, and cutting. Using this method, we obtain samples enriched for specific cell types from the mature osteoblast lineage (osteoblasts, lining cells, i...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344821/resistance-of-four-fixation-techniques-used-to-treat-subcondylar-fractures
#9
Lucas Cavalieri-Pereira, Guilherme Spagnol, Cássio Edvard Sverzut, Márcio de Moraes, Alexandre Elias Trivellato
OBJECTIVE: This study aimed to evaluate the resistance of four fixation techniques used to treat subcondylar fractures. The following techniques were evaluated: fixation with one 4-hole single straight plate; fixation with one 2-mm 4-hole system plate and one 1.5-mm 3-hole system plate; fixation with two 2-mm plates with a 3-hole anterior plate; and fixation with two 2-mm plates with four holes each. STUDY DESIGN: Each fixation technique was subjected to a resistance test...
January 17, 2018: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29344723/structural-associations-between-organelle-membranes-in-nectary-parenchyma-cells
#10
Silvia Rodrigues Machado, Elisa A Gregório, Tatiane M Rodrigues
The close association between membranes and organelles, and the intense chloroplast remodeling in parenchyma cells of extrafloral nectaries occurred only at the secretion time and suggest a relationship with the nectar secretion. Associations between membranes and organelles have been well documented in different tissues and cells of plants, but poorly explored in secretory cells. Here, we described the close physical juxtaposition between membranes and organelles, mainly with chloroplasts, in parenchyma cells of Citharexylum myrianthum (Verbenaeceae) extrafloral nectaries under transmission electron microscopy, using conventional and microwave fixation...
January 17, 2018: Planta
https://www.readbyqxmd.com/read/29343898/assessment-of-temporomandibular-joint-dysfunction-in-condylar-fracture-of-the-mandible-using-the-helkimo-index
#11
S Suhas, Sharad Ramdas, P P Lingam, H R Naveen Kumar, Aashish Sasidharan, R Aadithya
Introduction: Condylar fractures of the mandible are functionally important fractures as the condyle of the mandible being a part of the temporomandibular joint (TMJ) and can lead to TMJ dysfunction if not properly treated. Materials and Methods: This was a cross-sectional study of a total of 33 treated patients with fracture of the mandibular condyle who underwent examination as per the Helkimo index. Their dysfunction was quantified and clinicoepidemiological characteristics were assessed...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29343888/medial-femoral-condyle-vascularised-corticoperiosteal-graft-a-suitable-choice-for-scaphoid-non-union
#12
Samir Kumta, Sudhir Warrier, Leena Jain, Rani Ummal, Manik Menezes, Shrirang Purohit
Introduction: Scaphoid fractures are not very common and frequently remain undiagnosed, presenting in non-union and persistent wrist pain. Options for scaphoid fracture treatment have been described over several decades, however, none with an optimal solution to achieve union along with good hand function. We describe here, the use of vascularised corticoperiosteal bone grafts from the medial femoral condyle (MFC) as a solution for the difficult problem of scaphoid fracture non-union...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29343756/radiological-and-clinical-differences-among-three-assisted-technologies-in-pedicle-screw-fixation-of-adult-degenerative-scoliosis
#13
Yong Fan, Jin Peng Du, Ji Jun Liu, Jia Nan Zhang, Shi Chang Liu, Ding Jun Hao
The purpose of this study was to compare the clinical and radiological differences among three advanced guided technologies in adult degenerative scoliosis. A total of 1012 pedicle screws were inserted in 83 patients using a spine robot (group A), 886 screws were implanted in 75 patients using a drill guide template (group B), and 1276 screws were inserted in 109 patients using CT-based navigation (group C). Screw positions were evaluated using postoperative CT scans according to the Gertzbein and Robbins classification...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342830/methods-to-improve-osseointegration-of-dental-implants-in-low-quality-type-iv-bone-an-overview
#14
REVIEW
Hamdan S Alghamdi
Nowadays, dental implants have become more common treatment for replacing missing teeth and aim to improve chewing efficiency, physical health, and esthetics. The favorable clinical performance of dental implants has been attributed to their firm osseointegration, as introduced by Brånemark in 1965. Although the survival rate of dental implants over a 10-year observation has been reported to be higher than 90% in totally edentulous jaws, the clinical outcome of implant treatment is challenged in compromised (bone) conditions, as are frequently present in elderly people...
January 13, 2018: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29342496/-adverse-events-in-the-treatment-of-periprosthetic-fractures-around-the-knee-a-clinical-and-radiological-outcome-analysis
#15
Anna Janine Schreiner, Christoph Gonser, Christoph Ihle, Max Konstantin Zauleck, Tim Klopfer, Fabian Stuby, Ulrich Stöckle, Björn Gunnar Ochs
BACKGROUND: The incidence of periprosthetic fractures associated with total knee arthroplasty (PpFxK) has been reported to be 0.3 - 5.5%. 40% of all cases are related to revision TKA. The most common localisation is the distal femur. Classification is performed according to Rorabeck (RB). RB I - II fractures are usually treated with locked plating and retrograde intramedullary nailing, whereas RB III fractures are an indication for revision arthroplasty using a hinged endoprosthesis...
January 17, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29342324/different-atomic-terminations-associated-photocatalytic-nitrogen-fixation-of-bismuth-oxybromide-a-first-principles-study
#16
Hongxian Liu, Zhenxing Fang, Yongfei Su, Yuanli Suo, Shuping Huang, Yongfan Zhang, Kaining Ding
We have systematically investigated the electronic structures and activation capacities of BiOBr {001} facets with different atomic terminations by means of DFT methods. Our calculations reveal that oxygen vacancies (OVs) give a significant boost in band edges of the O-terminated BiOBr {001} facets, and excess electrons induced by OVs could exceed the reduction potentials of high-energy N2 intermediates. Interestingly, the Bi-terminated BiOBr {001} facets may be good candidates for photocatalytic nitrogen fixation due to the stronger activation ability of N2 molecules comparing with O-terminated BiOBr {001} facets with OVs...
January 17, 2018: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29342155/nanoscopic-x-ray-fluorescence-imaging-and-quantification-of-intracellular-key-elements-in-cryofrozen-friedreich-s-ataxia-fibroblasts
#17
Björn De Samber, Eline Meul, Brecht Laforce, Boel De Paepe, Joél Smet, Michiel De Bruyne, Riet De Rycke, Sylvain Bohic, Peter Cloetens, Rudy Van Coster, Peter Vandenabeele, Tom Vanden Berghe
Synchrotron radiation based nanoscopic X-ray fluorescence (SR nano-XRF) analysis can visualize trace level elemental distribution in a fully quantitative manner within single cells. However, in-air XRF analysis requires chemical fixation modifying the cell's chemical composition. Here, we describe first nanoscopic XRF analysis upon cryogenically frozen (-150°C) fibroblasts at the ID16A-NI 'Nano-imaging' end-station located at the European Synchrotron Radiation Facility (ESRF) in Grenoble (France). Fibroblast cells were obtained from skin biopsies from control and Friedreich's ataxia (FRDA) patients...
2018: PloS One
https://www.readbyqxmd.com/read/29342067/there-is-no-column-a-new-classification-for-acetabular-fractures
#18
Amir Herman, Shay Tenenbaum, Vladislav Ougortsin, Nachshon Shazar
BACKGROUND: The surgical treatment of acetabular fractures relies on the understanding of fracture architecture and their classification. The Judet and Letournel classification has been the cornerstone in understanding and treating acetabular fractures. Recently, there has been growing evidence of discrepancies and incompleteness in the Judet and Letournel classification, adversely affecting its clinical use. This study describes a novel comprehensive classification system that will direct surgical approach and fixation methods...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29342066/resident-participation-in-fixation-of-intertrochanteric-hip-fractures-analysis-of-the-nsqip-database
#19
Alexander L Neuwirth, Russell N Stitzlein, Madalyn G Neuwirth, Rachel K Kelz, Samir Mehta
BACKGROUND: Future generations of orthopaedic surgeons must continue to be trained in the surgical management of hip fractures. This study assesses the effect of resident participation on outcomes for the treatment of intertrochanteric hip fractures. METHODS: The National Surgical Quality Improvement Program (NSQIP) database (2010 to 2013) was queried for intertrochanteric hip fractures (International Classification of Diseases, 9th Revision, Clinical Modification [ICD-9-CM] code 820...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29342061/the-effect-of-alternative-bearing-surfaces-on-the-risk-of-revision-due-to-infection-in-minimally-stabilized-total-knee-replacement-an-analysis-of-326-603-prostheses-from-the-australian-orthopaedic-association-national-joint-replacement-registry
#20
Christopher J Vertullo, Peter L Lewis, Yi Peng, Stephen E Graves, Richard N de Steiger
BACKGROUND: The effect of alternative bearing materials on the risk of revision due to infection after total knee replacement remains uncertain. By reducing the immunomodulating polyethylene wear-particle burden and with different substrate bacterial adhesion properties, Oxinium oxidized zirconium and cross-linked polyethylene (XLPE) could alter infection risk. The purpose of the current study was to analyze the risk of revision for infection in 3 comparisons of bearing combinations. METHODS: To evaluate the risk of revision for infection with XLPE, cobalt-chromium (CoCr) on XLPE was compared with CoCr on non-cross-linked polyethylene (NXLPE)...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
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