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https://www.readbyqxmd.com/read/28544131/sclerocorneal-graft-and-sequential-removal-of-melted-cornea-after-severe-corneal-burn-with-perforation
#1
Anja Viestenz, Berthold Seitz, Hans-Gert Struck, Arne Viestenz
INTRODUCTION: Corneal burn grade IV usually leads to blindness. Several different surgical techniques remain challenging owing to the extensive tissue damage. Here, we introduce a novel technique with a 15 mm corneoscleral and limbal homologous graft combined with sequential autologous corneal removal ab interno, with a vitrectomy probe to save the anterior chamber angle. In vivo anatomy with optical coherence tomography is the surgical key. METHOD: A large 15 mm sclerocorneal graft is sutured on top of the remainder of the destroyed cornea and sclera after removal of the epithelium and conjunctiva, with anterior synechiolysis if necessary, peripheral iridectomy and conjunctivoplasty...
May 22, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28543020/morphological-and-functional-aspects-of-the-epidermis-of-the-sea-lamprey-petromyzon-marinus-throughout-development
#2
R Rodríguez-Alonso, M Megías, M A Pombal, P Molist
The development of the epidermis of sea lamprey Petromyzon marinus along the whole life cycle was studied using conventional staining techniques and lectin histochemistry. The epidermis undergoes variations in morphology and thickness throughout development. The simple cuboidal epithelium found in the epidermis of prolarvae becomes stratified cubic in the adult by increasing the number of cell layers. The cuticle thickness undergoes a steady increase during the larval period. There are changes in the glycoconjugate composition of the three main cell types of the P...
May 22, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28542904/can-resonance-frequency-analysis-rfa-detect-narrow-marginal-bone-defects-around-dental-implants-an-ex-vivo-animal-pilot-study
#3
Coral Jie Yao, Li Ma, Nikos Mattheos
BACKGROUND: Resonance Frequency Analysis (RFA) is widely applied to assess implant stability, as expressed by Implant Stability Quotient (ISQ). However, the relation between ISQ value and the presence and extent of narrow marginal bone defects around implants has not been documented. PURPOSE: To investigate the potential of RFA devices to identify the presence and extent of marginal bone defects around implants, as expressed by the ISQ values. MATERIALS AND METHODS: 28 Straumann bone level implants (BL) and 28 bone level tapered implants (BLT), were placed ex-vivo in porcine ribs...
May 25, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28541957/the-cutting-edge-of-retinopathy-of-prematurity-care-expanding-the-boundaries-of-diagnosis-and-treatment
#4
Yoshihiro Yonekawa, Benjamin J Thomas, Aristomenis Thanos, Bozho Todorich, Kimberly A Drenser, Michael T Trese, Antonio Capone
PURPOSE: To discuss the latest advances and controversies in the diagnosis and care of infants with retinopathy of prematurity (ROP). METHODS: Literature review. RESULTS: Retinopathy of prematurity remains a major global issue. Industrialized nations now treat profoundly premature infants with posterior and aggressive disease, and middle-income nations are experiencing ROP epidemics. Remote digital imaging may address the decreasing ratio of ROP providers to premature infants, in addition to improving patient care...
May 24, 2017: Retina
https://www.readbyqxmd.com/read/28541927/comparison-of-nitrogen-vacancy-complexes-in-diamond-and-cubic-sic-dose-dependencies-and-spin-hamiltonian-parameters
#5
Taras Leonidovych Petrenko, V Bryksa
At present nitrogen-vacancy (NV) complex in diamond is the most promising defect for application in the area of quantum computing. This provides a stimulus for extensive search of another defects in semiconductors with similar properties. Recently it was shown that N$_{C}$V$_{Si}$ defect complex in SiC is perspective for this goal as well. In the present work we perform comparative \textit{ab initio} studies of NV complexes in diamond and 3\textit{C}-SiC. We focus both on radiospectroscopic characterization of these defects and on calculation of equilibrium concentration of complexes in irradiated crystals...
May 25, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28541767/gas-filled-microbubbles-novel-mucosal-antigen-delivery-system-for-induction-of-anti-pathogen-s-immune-responses-in-the-gut
#6
Blaise Corthésy, Gilles Bioley
Despite important success in protecting individuals against many pathogenic infections, parenteral vaccination is not optimal to induce immunity at the site of pathogen entry, i.e. mucosal surfaces. Moreover, designing adequate delivery systems and safe adjuvants to overcome the inherent tolerogenic environment of the mucosal tissue is challenging, in particular in the gastrointestinal tract prone to antigen degradation. We recently demonstrated that intranasal administration of a Salmonella-derived antigen associated with gas-filled microbubbles induced specific Ab and T cell responses in the gut and was associated with a reduction in local and systemic bacterial load after oral Salmonella infection...
May 25, 2017: Gut Microbes
https://www.readbyqxmd.com/read/28540940/modelling-charge-transfer-processes-in-c-2-tetrahydrofuran-collision-for-ion-induced-radiation-damage-in-dna-building-blocks
#7
Ewa Erdmann, Marie-Christine Bacchus-Montabonel, Marta Łabuda
Investigations of collision-induced processes involving carbon ions and molecules of biological interest, in particular DNA building blocks, are crucial to model the effect of radiation on cells in order to improve medical treatments for cancer therapy. Using carbon ions appears to be one of the most efficient ways to increase biological effectiveness to damage cancerous cells by irradiating deep-seated tumors. Therefore, interest in accurate calculations to understand fundamental processes occurring in ion-molecule collision systems has been growing recently...
May 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28540732/mouse-model-of-colonization-of-the-digestive-tract-with-acinetobacter-baumannii-and-subsequent-pneumonia
#8
Noémie Coron, Silvie Pavlickova, Angélique Godefroy, Hélène Pailhoriès, Marie Kempf, Viviane Cassisa, Laurent Marsollier, Estelle Marion, Marie-Laure Joly-Guillou, Matthieu Eveillard
AIM: Implementing a mouse model of Acinetobacter baumannii (AB) digestive colonization and studying the propensity of an intestinal reservoir of AB to be at the origin of pneumonia. MATERIALS & METHODS: After a disruption of the digestive flora by piperacillin-tazobactam, two multidrug-resistant AB strains were intranasally inoculated to two cohorts of ten mice daily. For each strain, five mice were rendered transiently neutropenic. RESULTS & CONCLUSION: One strain persisted several weeks in the digestive tract, even after stopping piperacillin-tazobactam injections, leading to the hypothesis that some AB strains can authentically colonize the gut...
May 25, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28540719/one-step-toward-a-new-generation-of-c-mos-compatible-oxide-p-n-junctions-structure-of-the-lsmo-zno-interface-elucidated-by-an-experimental-and-theoretical-synergic-work
#9
Daniele Pullini, Mauro Francesco Sgroi, Agnes Nora Mahmoud, Nicolas Gauquelin, Lorenzo Maschio, Anna Maria Ferrari, Rik Groenen, Cas Damen, Guus Rijnders, Karel H W van den Bos, Sandra Van Aert, Johan Verbeeck
Heterostructures formed by La0.7Sr0.3MnO3/ZnO (LSMO/ZnO) interfaces exhibit extremely interesting electronic properties making them promising candidatea for novel oxide p-n junctions with multifunctional features. In this work, the structure of the interface is studied through a combined experimental/theoretical approach, . Hetero-structures were grown epitaxially and homogeneously on 4" silicon wafers, characterized by advanced electron microscopy imaging and spectroscopy, and simulated by ab-initio DFT calculations...
May 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28540696/negative-conversion-of-high-serum-p53-antibody-titers-in-a-patient-with-gastric-cancer-at-31%C3%A2-months-after-surgery
#10
Kenji Murayama, Tatsuki Nanami, Takashi Suzuki, Yoko Oshima, Satoshi Yajima, Tetsuo Nemoto, Hideaki Shimada
We performed distal gastrectomy with D2 lymph node dissection, pathological stage was Stage IB (T2N0M0), in a 68-year-old male with gastric adenocarcinoma. We then monitored serum p53 antibody titers for 5 years and found it consistently decreased, without disease recurrence. Although the s-p53-Ab titer remained positive even after 2 years, it decreased to 16.5, 4.45, 2.66, 1.55, and 1.18 U/ml at 3 months, 7 months, 1 year, 2 years and 3 years after surgery, respectively. The s-p53-Ab titer finally converted from positive to negative at 31 months postoperatively without any sign of recurrence by computed tomography examination at 5 years after surgery...
May 24, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28540182/mannose-binding-lectin-mbl-gene-polymorphisms-in-susceptibility-to-pulmonary-tuberculosis-among-the-lur-population-of-lorestan-province-of-iran
#11
Ali Amiri, Toomaj Sabooteh, Farhad Shahsavar, Khatereh Anbari, Flora Pouremadi
OBJECTIVE: Tuberculosis (TB) is caused by infection of Mycobacterium tuberculosis. Host genetic variability is an important determinant of the risk of developing TB in humans. Although the association between MBL polymorphisms and TB has been studied in various populations, the results are controversial. The aim of this study was to investigate mannose-binding lectin (MBL) gene polymorphisms with susceptibility to pulmonary tuberculosis (PTB) in a Lur population of Iran. METHODS: In this case-control study, four functional MBL gene polymorphisms (HL, XY, PQ and AB) were genotyped by using PCR Single Strand Conformation Polymorphism (SSCP) technique in a Lur population living in Lorestan Province, consisting of 100 patients with pulmonary tuberculosis (PTB) age and sex matched 100 healthy controls (HCs)...
June 2017: Genomics Data
https://www.readbyqxmd.com/read/28539866/effect-of-diet-on-type-2-diabetes-mellitus-a-review
#12
REVIEW
Waqas Sami, Tahir Ansari, Nadeem Shafique Butt, Mohd Rashid Ab Hamid
Globally, type 2 diabetes mellitus (T2DM) is considered as one of the most common diseases. The etiology of T2DM is complex and is associated with irreversible risk factors such as age, genetic, race, and ethnicity and reversible factors such as diet, physical activity and smoking. The objectives of this review are to examine various studies to explore relationship of T2DM with different dietary habits/patterns and practices and its complications. Dietary habits and sedentary lifestyle are the major factors for rapidly rising incidence of DM among developing countries...
April 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28539822/induction-of-mitotic-delay-in-pharyngeal-and-nasopharyngeal-carcinoma-cells-using-an-aqueous-extract-of-ajuga-bracteosa
#13
Yu-Tsai Lin, Chih-Che Lin, Hung-Chen Wang, Yi-Chiang Hsu
Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, for which radiotherapy and/or chemotherapy are the primary treatment methods. Many herbs are known to have potential uses in chemotherapy; however, the mechanisms underlying the observed antitumor activity of Ajuga bracteosa (AB) against NPC remain unclear. We explored the antitumor effects of AB, which was shown specifically to induce mitotic delay in pharyngeal (Detroit 562) and nasopharyngeal (Hone-1) cancer cells. Proliferation of cancer cells after exposure to aqueous extract of A...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28539436/nontrivial-berry-phase-in-magnetic-bamnsb2-semimetal
#14
Silu Huang, Jisun Kim, W A Shelton, E W Plummer, Rongying Jin
The subject of topological materials has attracted immense attention in condensed-matter physics because they host new quantum states of matter containing Dirac, Majorana, or Weyl fermions. Although Majorana fermions can only exist on the surface of topological superconductors, Dirac and Weyl fermions can be realized in both 2D and 3D materials. The latter are semimetals with Dirac/Weyl cones either not tilted (type I) or tilted (type II). Although both Dirac and Weyl fermions have massless nature with the nontrivial Berry phase, the formation of Weyl fermions in 3D semimetals require either time-reversal or inversion symmetry breaking to lift degeneracy at Dirac points...
May 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28539189/the-individual-and-population-genetics-of-antibody-immunity
#15
REVIEW
Corey T Watson, Jacob Glanville, Wayne A Marasco
Antibodies (Abs) produced by immunoglobulin (IG) genes are the most diverse proteins expressed in humans. While part of this diversity is generated by recombination during B-cell development and mutations during affinity maturation, the germ-line IG loci are also diverse across human populations and ethnicities. Recently, proof-of-concept studies have demonstrated genotype-phenotype correlations between specific IG germ-line variants and the quality of Ab responses during vaccination and disease. However, the functional consequences of IG genetic variation in Ab function and immunological outcomes remain underexplored...
May 20, 2017: Trends in Immunology
https://www.readbyqxmd.com/read/28539096/influence-of-olive-oil-on-alveolar-bone-response-during-orthodontic-retention-period-rabbit-model-study
#16
Afrah K Al-Hamdany, Ali R Al-Khatib, Hafidh I Al-Sadi
OBJECTIVES: This study attempted to evaluate clinically and histologically the effects of olive oil (Ol) consumption on orthodontic relapse after the retention period. DESIGN: Thirty apparently healthy female albino rabbits, weight more than 1000 g each was used in this study. The animals were grouped randomly into six groups of five animals each: two control and four experimental groups. In control groups, the relapse was estimated either at zero day, or at the end of the fourth week after orthodontic retention period...
May 24, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28538388/myxedema-coma-a-case-report-of-pediatric-emergency-care
#17
Yueniu Zhu, Wenjuan Qiu, Mengyan Deng, Xiaodong Zhu
RAIONALE: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases. PATIENT CONCERNS: A 6-year-old Chinese girl presented with coma and hypothermia preceded by pneumonia. Her lab results were: free thyroxin (T4) 4.18 pmol/L and thyroid-stimulating hormone (TSH) > 150 μIU/mL with extremely elevated anti-thyroid peroxidase (TPO-Ab) and anti-thyroglobulin...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28537944/behavioural-responses-of-zebrafish-larvae-to-acute-ethosuximide-exposure
#18
Yongxia Ji, Jia Lin, Xiaolan Peng, Xiuyun Liu, Fei Li, Yinglan Zhang, Ning Guo, Qiang Li
The anticonvulsant drug ethosuximide has shown diverse anxiety-related activity in rodents, but research in zebrafish is limited. To evaluate the effects of acute ethosuximide exposure on locomotor activity and anxiety-related thigmotaxis behaviours of zebrafish larvae, the activity of AB strain zebrafish larvae at 5 and 7 days postfertilization (dpf) was analysed under normal constant illumination and stressful light-dark transitions. Under constant illumination, ethosuximide at concentrations of 2, 5 and 10 mmol/l increased the distances travelled and intensified locomotor responses to a novel environment...
May 19, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28537729/stretching-induced-conductance-variations-as-fingerprints-of-contact-configurations-in-single-molecule-junctions
#19
Yong-Hoon Kim, Hu Sung Kim, Juho Lee, Makusu Tsutsui, Tomoji Kawai
Molecule-electrode contact atomic structures are a critical factor that characterizes molecular devices, but their precise understanding and control still remain elusive. Based on combined first-principles calculations and single-molecule break junction experiments, we herein establish that the conductance of alkanedithiolate junctions can both increase and decrease with mechanical stretching and the specific trend is determined by the S-Au linkage coordination number (CN) or the molecule-electrode contact atomic structure...
May 24, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28537223/structural-evolution-behavior-of-manganese-monophosphide-under-high-pressure-experimental-and-theoretical-study
#20
Zhenhai Yu, Wei Wu, Pengchao Lu, Jinggeng Zhao, Jinguang Cheng, Qingyang Hu, Ye Yuan, Xin Li, Cuiying Pei, Fengjiao Chen, Zhipeng Yan, Shuai Yan, Ke Yang, Jian Sun, Jianlin Luo, Lin Wang
The influence of external pressure on the structural properties of manganese monophosphides (MnP) at room temperature has been studied using in situ angle dispersive synchrotron x-ray powder diffraction (AD-XRD) with a diamond anvil cell. The crystal structure of MnP is stable between 0 to 15 GPa. However, the compressibility of b-axis is much larger than those of a- and c-axes. From this result we suggested that the occurrence of superconductivity in MnP was induced by suppression of the long-range antiferromagnetically ordered state rather than a structural phase transition...
May 24, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
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