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https://www.readbyqxmd.com/read/29150794/shunt-surgery-in-idiopathic-normal-pressure-hydrocephalus-is-cost-effective-a-cost-utility-analysis
#1
Mats Tullberg, Josefine Persson, Jakob Petersen, Per Hellström, Carsten Wikkelsø, Åsa Lundgren-Nilsson
BACKGROUND: The objective was to evaluate the cost-effectiveness of shunt surgery in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS: Health-related quality of life was evaluated before and 6 months after surgery using the EQ-5D-3 L (EuroQOL group five-dimensions health survey) in 30 patients (median age, 71 years; range, 65-89 years) diagnosed with iNPH. The costs associated with shunt surgery were assessed by a detailed survey with interviews and extraction of register data concerning the cost of hospital care, primary care, residential care, home-care service and informal care...
November 17, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29150767/cell-migration-in-1d-and-2d-nanofiber-microenvironments
#2
Horacio M Estabridis, Aniket Jana, Amrinder Nain, David J Odde
Understanding how cells migrate in fibrous environments is important in wound healing, immune function, and cancer progression. A key question is how fiber orientation and network geometry influence cell movement. Here we describe a quantitative, modeling-based approach toward identifying the mechanisms by which cells migrate in fibrous geometries having well controlled orientation. Specifically, U251 glioblastoma cells were seeded onto non-electrospinning Spinneret based tunable engineering parameters fiber substrates that consist of networks of suspended 400 nm diameter nanofibers...
November 17, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29150752/women-s-reproductive-health-in-sociocultural-context
#3
EDITORIAL
Yael Benyamini, Irina Todorova
PURPOSE: The special issue on Women's Reproductive Health in Cultural Context covers multiple dimensions of women's reproductive health and how it might be shaped by cultural meanings, social and gender inequities, and power differentials, employing a variety of methodological approaches. On the one hand, it aims to bring to the forefront the conversation about how women's health is uniquely experienced and constructed in local settings, and on the other hand, it aims to draw broader conclusions from a perspective of interconnectedness of women and the shared issues that they face...
November 17, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29150622/evidence-of-quantum-phase-transition-in-real-space-vacuum-entanglement-of-higher-derivative-scalar-quantum-field-theories
#4
S Santhosh Kumar, S Shankaranarayanan
In a bipartite set-up, the vacuum state of a free Bosonic scalar field is entangled in real space and satisfies the area-law- entanglement entropy scales linearly with area of the boundary between the two partitions. In this work, we show that the area law is violated in two spatial dimensional model Hamiltonian having dynamical critical exponent z = 3. The model physically corresponds to next-to-next-to-next nearest neighbour coupling terms on a lattice. The result reported here is the first of its kind of violation of area law in Bosonic systems in higher dimensions and signals the evidence of a quantum phase transition...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150186/articular-scaling-and-body-mass-estimation-in-platyrrhines-and-catarrhines-modern-variation-and-application-to-fossil-anthropoids
#5
Jonathan M G Perry, Siobhán B Cooke, Jacqueline A Runestad Connour, M Loring Burgess, Christopher B Ruff
Body mass is an important component of any paleobiological reconstruction. Reliable skeletal dimensions for making estimates are desirable but extant primate reference samples with known body masses are rare. We estimated body mass in a sample of extinct platyrrhines and Fayum anthropoids based on four measurements of the articular surfaces of the humerus and femur. Estimates were based on a large extant reference sample of wild-collected individuals with associated body masses, including previously published and new data from extant platyrrhines, cercopithecoids, and hominoids...
November 14, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/29149893/association-between-severity-of-illicit-drug-dependence-and-quality-of-life-in-a-psychosocial-care-center-in-brazil-cross-sectional-study
#6
Selva Rios Campêlo, Maria Alves Barbosa, Danilo Rocha Dias, Camila Cardoso Caixeta, Cláudio Rodrigues Leles, Celmo Celeno Porto
BACKGROUND: Quality of life must be one of the main purposes for the treatment of drug users, requiring a better understanding of the association between the quality of life and the severity of dependency. This study aimed to investigate the correlation between severity of substance use in various areas of human functioning and quality of life of illicit drug users in a psychosocial care center for alcohol and drugs. METHODS: This cross-sectional study included 60 participants - illicit drug users - treated at a psychosocial care center for alcohol and drugs...
November 17, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29149579/doing-for-the-greater-good-what-price-in-academe
#7
Suniya S Luthar
In discussing how merit is commonly judged in academia, my focus in this article is not on dimensions that are currently considered but on those that warrant more attention. Grounded in suggestions offered by Sternberg, I argue here for increased recognition of faculty's commitment to intrinsic values-focused on community and relationships-and not just extrinsic ones that connote personal fame or status. I first summarize evidence of disillusionment among today's promising young scholars and then provide exemplars of role models who have, in fact, maintained high standards in both intrinsic and extrinsic domains...
November 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29149323/should-the-dilated-ascending-aorta-be-repaired-at-the-time-of-bicuspid-aortic-valve-replacement
#8
Tsuyoshi Kaneko, Prem Shekar, Vladimir Ivkovic, Nicholas T Longford, Chuan-Chin Huang, Martin I Sigurdsson, Robert C Neely, Maroun Yammine, Julius I Ejilofor, Vanessa Montiero Vieira, Jasmine T Shahram, Karam M Habchi, Gregory W Malzberg, Peter S Martin, Jordan Bloom, Eric M Isselbacher, J Daniel Muehlschlegel, Thoralf M Sundt, Simon C Body
OBJECTIVES: Bicuspid aortic valve (BAV) is the most common congenital valvular abnormality and frequently presents with accelerated calcific aortic valve disease, requiring aortic valve replacement (AVR) and thoracic aortic aneurysm and dissection. Supporting evidence for Association Guidelines of aortic dimensions for aortic resection is sparse. We sought to determine whether concurrent repair of dilated or aneurysmal aortic disease during AVR in patients with BAV substantially improves morbidity and mortality outcomes...
November 14, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29149039/growth-of-anisotropic-gold-nanoparticle-assemblies-via-liposome-fusion
#9
Kouta Sugikawa, Tatsuya Kadota, Kotaro Matsuo, Kazuma Yasuhara, Atsushi Ikeda
Anisotropic assembly of nanoparticles (NPs) has attracted extensive attention because of the potential applications in materials science, biology, and medicine. However, assembly control (e.g., the number of assembled NPs) has not been adequately studied. Here, the growth of anisotropic gold NP assemblies on a liposome surface is reported. Citrate-coated gold NPs adsorbed on liposome surfaces were assembled in one dimension at temperatures above the phase transition temperature of the lipid bilayer. Growth of the anisotropic assemblies depended on the heating time...
November 17, 2017: Materials
https://www.readbyqxmd.com/read/29148697/synthesis-of-hierarchical-sisal-like-v2o5-with-exposed-stable-001-facets-as-long-life-cathode-materials-for-advanced-lithium-ion-batteries
#10
Naiteng Wu, Wuzhou Du, Guilong Liu, Zhan Zhou, Hong-Ru Fu, Qianqian Tang, Xianming Liu, Yan-Bing He
Vanadium pentoxide (V2O5) is considered a promising cathode material for advanced lithium-ion batteries due to its high specific capacity and low cost. However, the application of V2O5-based electrodes has been hindered by their inferior conductivity, cycling stability and power performance. Herein, hierarchical sisal-like V2O5 microstructures consisting of primary one-dimension (1D) nanobelt with [001] facets orientation growth and rich oxygen vacancies are synthesized through a facile hydrothermal process using polyoxyethylene-20-cetyl-ether as surface control agent, and followed by calcination...
November 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29148597/three-dimensional-analysis-of-bone-remodeling-following-ridge-augmentation-of-compromised-extraction-sockets-in-periodontitis-patients-a-randomized-controlled-study
#11
Mario Aimetti, Valeria Manavella, Lisa Corano, Elena Ercoli, Cristina Bignardi, Federica Romano
OBJECTIVES: The aim of this study was to analyze linear and volumetric hard tissue changes in severely resorbed alveolar sockets after ridge augmentation procedure and to compare them with spontaneous healing using three-dimensional cone beam computed tomography (CBCT). MATERIAL AND METHODS: Thirty patients (mean age 53.2 ± 6.3 years) requiring tooth extraction for advanced periodontitis were randomly allocated to test and control groups. The test sites were grafted using a collagenated bovine-derived bone (DBBM-C) covered with a collagen membrane, while control sites had spontaneous healing...
November 17, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29148432/a-singular-value-decomposition-linear-programming-svdlp-optimization-technique-for-circular-cone-based-robotic-radiotherapy
#12
Bin Liang, Yongbao Li, Wei Ran, Bin Guo, Xuang Xu, Bo Liu, Jiafeng Li, Qiuwen Wu, Fugen Zhou
With robot-controlled linac positioning, the robotic radiotherapy system such as CyberKnife significantly increases the freedom in radiation beam placement, but also imposes more challenges on treatment plan optimization. The resampling mechanism in vendor supplied treatment planning system (MultiPlan) could not fully explore the increased beam direction search space. Besides, a sparse treatment plan (using fewer beams) is desired to improve the treatment efficiency. This study proposes a singular value decomposition linear programming (SVDLP) optimization technique for circular collimator based robotic radiotherapy...
November 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29148096/performance-of-the-dimension-tac-assay-and-comparison-of-multiple-platforms-for-the-measurement-of-tacrolimus
#13
Eun-Jung Cho, Dae-Hyun Ko, Woochang Lee, Sail Chun, Hae-Kyung Lee, Won-Ki Min
BACKGROUND: Therapeutic monitoring of tacrolimus is essential for reducing organ rejection and adverse effects. The measurement of tacrolimus in whole blood is taken by many automated platforms. We evaluated the analytical performance of the Dimension TAC assay, which is an upgraded reagent from the previous Dimension TACR assay. METHODS: The evaluations involved determination of precision, linearity, detection capability, and reagent lot-to-lot variability between three lot numbers...
November 17, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29148092/an-inductively-coupled-ultra-thin-flexible-and-passive-rf-resonator-for-mri-marking-and-guiding-purposes-clinical-feasibility
#14
Akbar Alipour, Sayim Gokyar, Oktay Algin, Ergin Atalar, Hilmi Volkan Demir
PURPOSE: The purpose of this study is to develop a wireless, flexible, ultra-thin, and passive radiofrequency-based MRI resonant fiducial marker, and to validate its feasibility in a phantom model and several body regions. METHODS: Standard microfabrication processing was used to fabricate the resonant marker. The proposed marker consists of two metal traces in the shape of a square with an edge length of 8 mm, with upper and lower traces connected to each other by a metalized via...
November 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29148084/size-shape-and-sex-dependent-variation-in-force-production-by-crayfish-chelae
#15
Brian M Malavé, Joseph M Styga, Ethan D Clotfelter
The ability to generate large closing forces is important for many animals. Several studies have demonstrated that bite or pinching force capacity is usually related to the linear dimensions of the closing apparatus. However, relatively few studies have applied geometric morphometrics to examine the effects of size-independent shape on force production, particularly in studies of crustacean pinching force. In this study, we utilized traditional and geometric morphometric techniques to compare the pinching force of Procambarus clarkii crayfish to their chela morphology...
November 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29147699/strain-relaxation-and-ambipolar-electrical-transport-in-gaas-insb-core-shell-nanowires
#16
Torsten Rieger, Patrick Zellekens, Natalia Demarina, Ali Al Hassan, Franz Josef Hackemüller, Hans Lüth, Ullrich Pietsch, Thomas Schäpers, Detlev Grützmacher, Mihail Ion Lepsa
The growth, crystal structure, strain relaxation and room temperature transport characteristics of GaAs/InSb core-shell nanowires grown using molecular beam epitaxy are investigated. Due to the large lattice mismatch between GaAs and InSb of 14%, a transition from island-based to layer-like growth occurs during the formation of the shell. High resolution transmission electron microscopy in combination with geometric phase analyses as well as X-ray diffraction with synchrotron radiation are used to investigate the strain relaxation and prove the existence of different dislocations relaxing the strain on zinc blende and wurtzite core-shell nanowire segments...
November 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/29147698/molecular-spin-qudits-for-quantum-algorithms
#17
REVIEW
Eufemio Moreno-Pineda, Clément Godfrin, Franck Balestro, Wolfgang Wernsdorfer, Mario Ruben
Presently, one of the most ambitious technological goals is the development of devices working under the laws of quantum mechanics. One prominent target is the quantum computer, which would allow the processing of information at quantum level for purposes not achievable with even the most powerful computer resources. The large-scale implementation of quantum information would be a game changer for current technology, because it would allow unprecedented parallelised computation and secure encryption based on the principles of quantum superposition and entanglement...
November 17, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29147146/relationships-between-short-and-fast-brain-timescales
#18
Eva Déli, Arturo Tozzi, James F Peters
Brain electric activity exhibits two important features: oscillations with different timescales, characterized by diverse functional and psychological outcomes, and a temporal power law distribution. In order to further investigate the relationships between low- and high- frequency spikes in the brain, we used a variant of the Borsuk-Ulam theorem which states that, when we assess the nervous activity as embedded in a sphere equipped with a fractal dimension, we achieve two antipodal points with similar features (the slow and fast, scale-free oscillations)...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29146967/splenic-glucocorticoid-resistance-following-psychosocial-stress-requires-physical-injury
#19
Sandra Foertsch, Andrea M Füchsl, Sandra D Faller, Hannah Hölzer, Dominik Langgartner, Joanna Messmann, Gudrun Strauß, Stefan O Reber
Mice exposed to chronic subordinate colony housing (CSC) stress show glucocorticoid (GC) resistance of in vitro lipopolysaccharide (LPS)-stimulated splenocytes, increased anxiety and colitis. Similar effects were reported in wounded mice exposed to social disruption (SDR). Here we show that CSC exposure induced GC resistance in isolated and in vitro LPS-stimulated, but not unstimulated, splenocytes, and these effects were absent when CD11b(+) splenocytes were depleted. Moreover, re-active coping behaviour during CSC correlated with the attacks and bites received by the resident, which in turn highly correlated with the dimension of splenic GC resistance, as with basal and LPS-induced in vitro splenocyte viability...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29146960/assessing-species-biomass-contributions-in-microbial-communities-via-metaproteomics
#20
Manuel Kleiner, Erin Thorson, Christine E Sharp, Xiaoli Dong, Dan Liu, Carmen Li, Marc Strous
Microbial community structure can be analyzed by quantifying cell numbers or by quantifying biomass for individual populations. Methods for quantifying cell numbers are already available (e.g., fluorescence in situ hybridization, 16-S rRNA gene amplicon sequencing), yet high-throughput methods for assessing community structure in terms of biomass are lacking. Here we present metaproteomics-based methods for assessing microbial community structure using protein abundance as a measure for biomass contributions of individual populations...
November 16, 2017: Nature Communications
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