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Uma S Babu, Monika Proszkowiec-Weglarz, Girdhari M Sharma, Marion Pereira, Kannan V Balan
Salmonella enterica serovar Oranienburg (SO) was linked to a human salmonellosis outbreak in the Midwest in 2015 and 2016 from consumption of eggs. However, unlike Salmonella enterica serovar Enteritidis (SE), little is known regarding the potential of SO to colonize in laying hens and contaminate eggs. We used in vivo and in vitro models to evaluate tissue colonization and survival capacity of SO. Twenty eight-week-old laying hens were each challenged with an oral dose of approximately 107 (n = 92) or 109 (n = 96) colony-forming units (CFU) in 1 mL saline and evaluated after 1, 2, and 4 wk...
May 18, 2018: Poultry Science
Iván C Balán, Timothy Frasca, Curtis Dolezal, Alex Carballo-Diéguez
No abstract text is available yet for this article.
May 4, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Ramya Cheramangalath Balan, Rajakumar Balla
Cl-initiated photo-oxidation reaction of methyl propionate was investigated experimentally using relative rate method. Gas chromatography/mass spectrometry (GC-MS) and GC/infrared spectroscopy (GC-IR) were used as analytical tools to follow the concentrations of reactants and products during reaction. The gas-phase kinetics of methyl propionate with Cl atoms was measured over the temperature range of 263-363 K at 760 Torr in N2 atmosphere using C2 H6 and C2 H4 as reference compounds. The temperature-dependent rate coefficient for the reaction of methyl propionate with Cl atom was obtained as k(T) = [(3...
May 15, 2018: Environmental Science and Pollution Research International
Thapelo Mokomele, Leonardo da Costa Sousa, Venkatesh Balan, Eugéne van Rensburg, Bruce E Dale, Johann F Görgens
Background: Expanding biofuel markets are challenged by the need to meet future biofuel demands and mitigate greenhouse gas emissions, while using domestically available feedstock sustainably. In the context of the sugar industry, exploiting under-utilized cane leaf matter (CLM) in addition to surplus sugarcane bagasse as supplementary feedstock for second-generation ethanol production has the potential to improve bioenergy yields per unit land. In this study, the ethanol yields and processing bottlenecks of ammonia fibre expansion (AFEX™) and steam explosion (StEx) as adopted technologies for pretreating sugarcane bagasse and CLM were experimentally measured and compared for the first time...
2018: Biotechnology for Biofuels
Linda Pudelko, Steven Edwards, Mirela Balan, Daniel Nyqvist, Jonathan Al-Saadi, Johannes Dittmer, Ingrid Almlöf, Thomas Helleday, Lars Bräutigam
Background: Glioblastoma (GBM) is an aggressive form of brain cancer with poor prognosis. Although murine animal models have given valuable insights into the GBM disease biology, they cannot be used in high-throughput screens to identify and profile novel therapies. The only vertebrate model suitable for large-scale screens, the zebrafish, has proven to faithfully recapitulate biology and pathology of human malignancies and clinically relevant orthotopic zebrafish models have been developed...
May 10, 2018: Neuro-oncology
Aravind Puthirath Balan, Sruthi Radhakrishnan, Cristiano F Woellner, Shyam K Sinha, Liangzi Deng, Carlos de Los Reyes, Banki Manmadha Rao, Maggie Paulose, Ram Neupane, Amey Apte, Vidya Kochat, Robert Vajtai, Avetik R Harutyunyan, Ching-Wu Chu, Gelu Costin, Douglas S Galvao, Angel A Martí, Peter A van Aken, Oomman K Varghese, Chandra Sekhar Tiwary, Anantharaman Malie Madom Ramaswamy Iyer, Pulickel M Ajayan
With the advent of graphene, the most studied of all two-dimensional materials, many inorganic analogues have been synthesized and are being exploited for novel applications. Several approaches have been used to obtain large-grain, high-quality materials. Naturally occurring ores, for example, are the best precursors for obtaining highly ordered and large-grain atomic layers by exfoliation. Here, we demonstrate a new two-dimensional material 'hematene' obtained from natural iron ore hematite (α-Fe2 O3 ), which is isolated by means of liquid exfoliation...
May 7, 2018: Nature Nanotechnology
Shabeesh Balan, Manabu Toyoshima, Takeo Yoshikawa
Schizophrenia is one of the leading causes of disability among mental disorders, contributing to a substantial socioeconomic burden. Our understanding of the mechanisms of the pathogenesis of the disease has largely been limited by its inherent complexity imparted by the polygenicity and interactions with environmental factors. Since pathobiological events are initiated in the schizophrenic brain long before the onset of the psychotic manifestations, characterizing these processes is limited, mainly due to a lack of access to neuronal tissues...
May 2, 2018: Neurobiology of Disease
Anakkathil Balan Sudeep, Neda Shaikh, Youwaraj Ghodke, Viswas Ingale, Mangesh Gokhale
Chittoor virus (CHITV), a mosquito-borne bunyavirus (Orthobunyavirus: Bunyaviridae) isolated in India, has been found to be antigenically close to the Batai virus (BATV),which has a wide distribution across Asia, Europe and Africa. The latter causes influenza-like illness in humans and mild illness in sheep and goats. BATV has been involved in genetic reassortment with other bunyaviruses, generating novel genome combinations and causing severe clinical manifestations including hemorrhagic fever. Conversely, CHITV has never been associated with any major outbreaks in India, although neutralizing antibodies have been detected in humans and domestic animals...
May 2, 2018: Canadian Journal of Microbiology
Dongmei Tong, Erik Lönnblom, Anthony C Y Yau, Kutty Selva Nandakumar, Bibo Liang, Changrong Ge, Johan Viljanen, Lei Li, Mirela Bãlan, Lars Klareskog, Andrei S Chagin, Inger Gjertsson, Jan Kihlberg, Ming Zhao, Rikard Holmdahl
Background: Collagen XI (CXI) is a heterotrimeric molecule with triple helical structure in which the α3(XI) chain is identical to the α1(II) chain of collagen II (CII), but with extensive posttranslational modifications. CXI molecules are intermingled in the cartilage collagen fibers, which are mainly composed of CII. One of the alpha chains in CXI is shared with CII and contains the immunodominant T cell epitope, but it is unclear whether there are shared B cell epitopes as the antibodies tend to recognize the triple helical structures...
2018: Frontiers in Immunology
Md Shaifur Rahman, Lucas-Sebastian Spitzhorn, Wasco Wruck, Carsten Hagenbeck, Percy Balan, Nina Graffmann, Martina Bohndorf, Audrey Ncube, Pascale V Guillot, Tanja Fehm, James Adjaye
BACKGROUND: Established therapies for managing kidney dysfunction such as kidney dialysis and transplantation are limited due to the shortage of compatible donated organs and high costs. Stem cell-based therapies are currently under investigation as an alternative treatment option. As amniotic fluid is composed of fetal urine harboring mesenchymal stem cells (AF-MSCs), we hypothesized that third-trimester amniotic fluid could be a novel source of renal progenitor and differentiated cells...
April 25, 2018: Stem Cell Research & Therapy
Marius Alexandru Moga, Oana Gabriela Dimienescu, Andreea Bălan, Ioan Scârneciu, Barna Barabaș, Liana Pleș
Botulinum toxins (BoNTs) are produced by several anaerobic species of the genus Clostridium and, although they were originally considered lethal toxins, today they find their usefulness in the treatment of a wide range of pathologies in various medical specialties. Botulinum neurotoxin has been identified in seven different isoforms (BoNT-A, BoNT-B, BoNT-C, BoNT-D, BoNT-E, BoNT-F, and BoNT-G). Neurotoxigenic Clostridia can produce more than 40 different BoNT subtypes and, recently, a new BoNT serotype (BoNT-X) has been reported in some studies...
April 21, 2018: Toxins
Irina Balan, Kaitlin T Warnock, Adam Puche, Marjorie C Gondre-Lewis, Harry June, Laure Aurelian
Alcoholism initiates with episodes of excessive alcohol drinking, known as binge drinking, which is one form of excessive drinking (NIAAA Newsletter, 2004) that is related to impulsivity and anxiety (Ducci et al., 2007; Edenberg et al., 2004) and is also predictive of smoking status. The predisposition of non-alcohol exposed subjects to initiate binge drinking is controlled by neuroimmune signaling that includes an innately activated neuronal Toll-like receptor 4 (TLR4) signal. This signal also regulates cognitive impulsivity, a heritable trait that defines drug abuse initiation...
April 21, 2018: Brain Sciences
Olouyomi Gnimassou, Rodrigo Fernández-Verdejo, Matthew Brook, Damien Naslain, Estelle Balan, Mariwan Sayda, Jessica Cegielski, Henri Nielens, Anabelle Decottignies, Jean-Baptiste Demoulin, Kenneth Smith, Philip J Atherton, Marc Francaux, Louise Deldicque
We hypothesized that a single session of resistance exercise performed in moderate hypoxic (FiO2 : 14%) environmental conditions would potentiate the anabolic response during the recovery period spent in normoxia. Twenty subjects performed a 1-leg knee extension session in normoxic or hypoxic conditions. Muscle biopsies were taken 15 min and 4 h after exercise in the vastus lateralis of the exercised and the nonexercised legs. Blood and saliva samples were taken at regular intervals before, during, and after the exercise session...
April 19, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Daniel Balan, Orsolya Martha, Calin Bogdan Chibelean, Sabin Tataru, Septimiu Voidezan, Anca Sin, Victor Deliu Matei, Mihai Dorin Vartolomei, Giuseppe Lucarelli, Antonio Cioffi, Francesco Del Giudice, Ettore De Berardinis, Angela Borda, Gian Maria Busetto, Matteo Ferro, Akos Pytel, Daniel Porav-Hodade
To compare long-term overall survival (OS) in patients with G1 and G2 grade Ta bladder cancer after transurethral resection of bladder tumors (TURBTs). Secondary aim was to investigate clinical and pathologic prognostic factors for OS of Ta patients, except G3/high grade (HG).A total of 243 patients, retrospectively selected, with Ta nonmuscle invasive bladder cancer (NMIBC) underwent TURBT between January 2006 and December 2008 (median follow-up 109 months). Inclusion criteria were: Ta at first manifestation, G1 or G2 grade with no associated carcinoma in situ (CIS)...
April 2018: Medicine (Baltimore)
Federico Martinelli, Gina Cannarozzi, Bipin Balan, Fredy Siegrist, Annett Weichert, Regula Blösch, Zerihun Tadele
Tef [Eragrostis tef (Zucc.) Trotter], a staple food crop in the Horn of Africa and particularly in Ethiopia, has several beneficial agronomical and nutritional properties, including waterlogging and drought tolerance. In this study, we performed microRNA profiling of tef using the Illumina HiSeq 2500 platform, analyzing both shoots and roots of two tef genotypes, one drought-tolerant (Tsedey) and one drought-susceptible (Alba). We obtained more than 10 million filtered reads for each of the 24 sequenced small cDNA libraries...
March 29, 2018: Journal of Plant Physiology
Ana Marcos-Pinto, Luís Soares-de-Almeida, João Borges-Costa
Context: A variety of nonvenereal diseases can affect the penis and diminish quality of life. Many present similar clinical features and a cutaneous biopsy may be necessary to clarify the diagnosis. Aims: To characterize nonvenereal penile dermatoses with histological confirmation in a southwestern Europe hospital during a 9-year period. Materials and Methods: A retrospective study was conducted. We reviewed all penile biopsies performed between January 1, 2007 and December 31, 2015 and studied the causes of the nonvenereal penile dermatoses...
March 2018: Indian Dermatology Online Journal
Tom C Nguyen, Juan B Umana-Pizano, Gina P Landinez, Prakash Balan
No abstract text is available yet for this article.
April 4, 2018: Seminars in Thoracic and Cardiovascular Surgery
Hafis Muhammed, Ram V Nampoothiri, Balan Louis Gaspar, Sanjay Jain
No abstract text is available yet for this article.
April 5, 2018: BMJ Case Reports
Rahul Malhotra, Choy-Lye Chei, Edward Balan Menon, Wai-Leng Chow, Stella Quah, Angelique Chan, Shweta Ajay, David Bruce Matchar
Objective To delineate positive aspects of caregiving trajectories among family caregivers of stroke-survivors and determine the impact of stroke-survivor disability, a time-varying factor, on the delineated trajectories. Methods In a longitudinal study, family caregivers of 173 stroke-survivors in Singapore were administered the Positive Aspects of Caregiving scale (PAC scale) thrice (baseline/3 months/6 months). Group-based trajectory modeling delineated positive aspects of caregiving trajectories and identified the impact of stroke-survivor disability on the trajectories...
March 26, 2018: Topics in Stroke Rehabilitation
Roberto Lewis-Fernández, Angela A Coombs, Iván C Balán, Alejandro Interian
No abstract text is available yet for this article.
March 6, 2018: Journal of Clinical Psychiatry
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