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https://www.readbyqxmd.com/read/28214452/calorie-counting-and-fitness-tracking-technology-associations-with-eating-disorder-symptomatology
#1
Courtney C Simpson, Suzanne E Mazzeo
The use of online calorie tracking applications and activity monitors is increasing exponentially. Anecdotal reports document the potential for these trackers to trigger, maintain, or exacerbate eating disorder symptomatology. Yet, research has not examined the relation between use of these devices and eating disorder-related attitudes and behaviors. This study explored associations between the use of calorie counting and fitness tracking devices and eating disorder symptomatology. Participants (N=493) were college students who reported their use of tracking technology and completed measures of eating disorder symptomatology...
February 9, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28214127/functionalized-superparamagnetic-iron-oxide-nanoparticles-provide-highly-efficient-iron-labeling-in-macrophages-for-magnetic-resonance-based-detection-in-vivo
#2
Jack Sharkey, Philip J Starkey Lewis, Michael Barrow, Salamah M Alwahsh, June Noble, Eilidh Livingstone, Ross J Lennen, Maurits A Jansen, Jaime Garcia Carrion, Neill Liptrott, Shareen Forbes, Dave J Adams, Amy E Chadwick, Stuart J Forbes, Patricia Murray, Matthew J Rosseinsky, Christopher E Goldring, B Kevin Park
BACKGROUND AIMS: Tracking cells during regenerative cytotherapy is crucial for monitoring their safety and efficacy. Macrophages are an emerging cell-based regenerative therapy for liver disease and can be readily labeled for medical imaging. A reliable, clinically applicable cell-tracking agent would be a powerful tool to study cell biodistribution. METHODS: Using a recently described chemical design, we set out to functionalize, optimize and characterize a new set of superparamagnetic iron oxide nanoparticles (SPIONs) to efficiently label macrophages for magnetic resonance imaging-based cell tracking in vivo...
February 15, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28213914/novel-method-to-assess-intrinsic-heart-rate-recovery-in-ambulatory-ecg-recordings-tracks-cardioprotective-effects-of-chronic-autonomic-regulation-therapy-in-patients-enrolled-in-the-anthem-hf-study
#3
Gerrard M Carlson, Imad Libbus, Badri Amurthur, Bruce H KenKnight, Richard L Verrier
BACKGROUND: Postexercise heart rate recovery (HRR) is a powerful and independent predictor of mortality. Autonomic regulation therapy (ART) with chronic vagus nerve stimulation (VNS) has been shown to improve ventricular function in patients with chronic heart failure. However, the effect of ART on HRR in patients with heart failure remains unknown. METHODS: A new measure involving quantification of intrinsic HRR was developed for 24-hr ambulatory ECG (AECG) recordings based on spontaneous heart rate changes observed during daily activity in patients with symptomatic heart failure and reduced ejection fraction...
February 17, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28213127/quantitation-of-lead-210-210-pb-using-lead-203-203-pb-as-a-massless-yield-tracer
#4
D May, A N Nelson, M K Schultz
Determination of Pb-210 ((210)Pb) in aqueous solution is a common radioanalytical challenge in environmental science. Widely used methods for undertaking these analyses (e.g., ASTM D7535) rely on the use of stable lead (Pb) as a yield tracer that takes into account losses of (210)Pb that inevitably occur during elemental/radiochemical separations of the procedures. Although effective, these methods introduce technical challenges that can be difficult to track and potentially introduce uncertainty that can be difficult to quantify...
February 14, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28212087/dual-deep-network-for-visual-tracking
#5
Zhizhen Chi, Hongyang Li, Huchuan Lu, Minghsuan Yang
Visual tracking addresses the problem of identifying and localizing an unknown target in a video given the target specified by a bounding box in the first frame. In this paper, we propose a dual network to better utilize features among layers for visual tracking. It is observed that features in higher layers encode semantic context while its counterparts in lower layers are sensitive to discriminative appearance. Thus we exploit the hierarchical features in different layers of a deep model and design a dual structure to obtain better feature representation from various streams, which is rarely investigated in previous work...
February 15, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28212075/towards-photoplethysmography-based-estimation-of-instantaneous-heart-rate-during-physical-activity
#6
Delaram Jarchi, Alex Casson
OBJECTIVE: Recently numerous methods have been proposed for estimating average heart rate using photoplethysmography (PPG) during physical activity, overcoming the significant interference that motion causes in PPG traces. We propose a new algorithm framework for extracting instantaneous heart rate from wearable PPG and ECG signals to provide an estimate of heart rate variability during exercise. METHODS: For ECG signals we propose a new spectral masking approach which modifies a particle filter tracking algorithm, and for PPG signals constrains the instantaneous frequency obtained from the Hilbert transform to a region of interest around a candidate heart rate measure...
February 13, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28211965/first-synthesis-of-an-oridonin-conjugated-iridium-iii-complex-for-the-intracellular-tracking-of-nf-%C3%AE%C2%BAb-in-living-cells
#7
Wanhe Wang, Chao Yang, Sheng Lin, Kasipandi Vellaisamy, Guodong Li, Weihong Tan, Chung-Hang Leung, Dik-Lung Ma
NF-κB is a critical transcription factor that plays an important role in mediating inflammation, the immune response, and cell proliferation. The activation of NF-κB leads to an enhancement of proinflammatory mediator expression, which is implicated in the pathogenesis of a variety of diseases. Therefore, methods that allow the intracellular tracking of NF-κB are particularly attractive as they can provide information regarding the pathways or stimulation responses that are involved in the activation of NF-κB...
February 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28211844/a-tool-named-iris-for-versatile-high-throughput-phenotyping-in-microorganisms
#8
George Kritikos, Manuel Banzhaf, Lucia Herrera-Dominguez, Alexandra Koumoutsi, Morgane Wartel, Matylda Zietek, Athanasios Typas
Advances in our ability to systematically introduce and track controlled genetic variance in microorganisms have, in the past decade, fuelled high-throughput reverse genetics approaches. When coupled to quantitative readouts, such approaches are extremely powerful at elucidating gene function and providing insights into the underlying pathways and the overall cellular network organization. Yet, until now, all efforts to quantify microbial macroscopic phenotypes have been restricted to monitoring growth in a small number of model microorganisms...
February 17, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28210658/patellar-maltracking-persists-in-adolescent-females-with-patellofemoral-pain-a-longitudinal-study
#9
Victor R Carlson, Barry P Boden, Aricia Shen, Jennifer N Jackson, Katharine E Alter, Frances T Sheehan
BACKGROUND: Patellofemoral pain is one of the most common conditions seen in sports medicine practices, particularly among adolescent females. However, the natural history of the underlying pathology in patellofemoral pain during puberty remains poorly understood. PURPOSE: The purpose of this longitudinal study is to assess changes in patellar maltracking patterns in subjects with patellofemoral pain as they mature from mid- to late adolescence. STUDY DESIGN: Cohort study; Level of evidence, 3...
February 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28208763/iterative-development-of-an-online-dietary-recall-tool-intake24
#10
Emma Simpson, Jennifer Bradley, Ivan Poliakov, Dan Jackson, Patrick Olivier, Ashley J Adamson, Emma Foster
Collecting large-scale population data on dietary intake is challenging, particularly when resources and funding are constrained. Technology offers the potential to develop novel ways of collecting large amounts of dietary information while making it easier, more convenient, intuitive, and engaging for users. INTAKE24 is an online multiple pass 24 h dietary recall tool developed for use in national food and nutrition surveys. The development of INTAKE24 was a four-stage iterative process of user interaction and evaluation with the intended end users, 11-24 years old...
February 9, 2017: Nutrients
https://www.readbyqxmd.com/read/28208719/micro-computed-tomography-detection-of-gold-nanoparticle-labelled-mesenchymal-stem-cells-in-the-rat-subretinal-layer
#11
Pooi Ling Mok, Sue Ngein Leow, Avin Ee-Hwan Koh, Hairul Harun Mohd Nizam, Suet Lee Shirley Ding, Chi Luu, Raduan Ruhaslizan, Hon Seng Wong, Wan Haslina Wan Abdul Halim, Min Hwei Ng, Ruszymah Binti Hj Idrus, Shiplu Roy Chowdhury, Catherine Mae-Lynn Bastion, Suresh Kumar Subbiah, Akon Higuchi, Abdullah A Alarfaj, Kong Yong Then
Mesenchymal stem cells are widely used in many pre-clinical and clinical settings. Despite advances in molecular technology; the migration and homing activities of these cells in in vivo systems are not well understood. Labelling mesenchymal stem cells with gold nanoparticles has no cytotoxic effect and may offer suitable indications for stem cell tracking. Here, we report a simple protocol to label mesenchymal stem cells using 80 nm gold nanoparticles. Once the cells and particles were incubated together for 24 h, the labelled products were injected into the rat subretinal layer...
February 8, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28208620/a-review-of-wearable-technologies-for-elderly-care-that-can-accurately-track-indoor-position-recognize-physical-activities-and-monitor-vital-signs-in-real-time
#12
REVIEW
Zhihua Wang, Zhaochu Yang, Tao Dong
Rapid growth of the aged population has caused an immense increase in the demand for healthcare services. Generally, the elderly are more prone to health problems compared to other age groups. With effective monitoring and alarm systems, the adverse effects of unpredictable events such as sudden illnesses, falls, and so on can be ameliorated to some extent. Recently, advances in wearable and sensor technologies have improved the prospects of these service systems for assisting elderly people. In this article, we review state-of-the-art wearable technologies that can be used for elderly care...
February 10, 2017: Sensors
https://www.readbyqxmd.com/read/28207341/visual-loss-and-subsequent-activity-limitations-in-the-elderly-the-french-three-city-cohort
#13
Karine Pérès, Fanny Matharan, Vincent Daien, Virginie Nael, Arlette Edjolo, Isabelle Bourdel-Marchasson, Karen Ritchie, Christophe Tzourio, Cécile Delcourt, Isabelle Carrière
OBJECTIVES: To investigate the relationship between vision and disability in the elderly. METHODS: We used a baseline visual indicator (combining near acuity with Snellen equivalent < 20/30 and self-reported distance visual loss) to explore the association between visual loss and subsequent disability (mobility, instrumental activities of daily living [IADLs], ADLs, and participation restriction) from 1999 to 2007 in 8491 elderly participants of the French Three-City Cohort (Bordeaux, Dijon, and Montpellier)...
February 16, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28204846/regulation-of-end-binding-protein-eb1-in-the-control-of-microtubule-dynamics
#14
REVIEW
Anne Nehlig, Angie Molina, Sylvie Rodrigues-Ferreira, Stéphane Honoré, Clara Nahmias
The regulation of microtubule dynamics is critical to ensure essential cell functions, such as proper segregation of chromosomes during mitosis or cell polarity and migration. End-binding protein 1 (EB1) is a plus-end-tracking protein (+TIP) that accumulates at growing microtubule ends and plays a pivotal role in the regulation of microtubule dynamics. EB1 autonomously binds an extended tubulin-GTP/GDP-Pi structure at growing microtubule ends and acts as a molecular scaffold that recruits a large number of regulatory +TIPs through interaction with CAP-Gly or SxIP motifs...
February 15, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28202571/temporal-dynamics-of-retinal-and-extraretinal-signals-in-the-fefsem-during-smooth-pursuit-eye-movements
#15
Leah Bakst, Jerome Fleuriet, Michael J Mustari
Neurons in the smooth eye movement subregion of the Frontal Eye Field (FEFsem) are known to play an important role in voluntary smooth pursuit eye movements. Underlying this function are projections to parietal and prefrontal visual association areas and subcortical structures, all known to play vital, but differing roles in the execution of smooth pursuit. Additionally, the FEFsem has been shown to carry a diverse array of signals (e.g. eye velocity, acceleration, gain control). We hypothesized that distinct subpopulations of FEFsem neurons subserve these diverse functions and projections, and that the relative weights of retinal and extraretinal signals could form the basis for categorization of units...
February 15, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28202527/-18f-2s-4r-4-fluoroglutamine-pet-detects-glutamine-pool-size-changes-in-triple-negative-breast-cancer-in-response-to-glutaminase-inhibition
#16
Rong Zhou, Austin R Pantel, Shihong Li, Brian P Lieberman, Karl Ploessl, Hoon Choi, Eric Blankemeyer, Hsiaoju Lee, Hank Kung, Robert H Mach, David Mankoff
Glutaminolysis is a metabolic pathway adapted by many aggressive cancers, including triple-negative breast cancers (TNBC), to utilize glutamine for survival and growth. In this study, we examined the utility of [18F](2S,4R)4-fluoroglutamine ([18F]4F-Gln) PET to measure tumor cellular glutamine pool size, whose change might reveal the pharmacodynamic (PD) effect of drugs targeting this cancer-specific metabolic pathway. High glutaminase (GLS) activity in TNBC tumors resulted in low cellular glutamine pool size assayed via high-resolution 1H magnetic resonance spectroscopy (MRS)...
February 15, 2017: Cancer Research
https://www.readbyqxmd.com/read/28199052/the-flipped-classroom-approach-stimulating-positive-learning-attitudes-and-improving-mastery-of-histology-among-medical-students
#17
Xin Cheng, Kenneth Ka Ho Lee, Eric Y Chang, Xuesong Yang
Traditional medical education methodologies have been dramatically impacted by the introduction of new teaching approaches over the past few decades. In particular, the "flipped classroom" format has drawn a great deal of attention. However, evidence regarding the effectiveness of the flipped model remains limited due to a lack of outcome-based studies. In the present study, a pilot histology curriculum of the organ systems was implemented among 24 Traditional Chinese Medicine (TCM) students in a flipped classroom format at Jinan University...
November 4, 2016: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28198848/three-wavelengths-parallel-phase-shift-interferometry-for-real-time-focus-tracking-and-vibration-measurement
#18
Michael Ney, Avner Safrani, Ibrahim Abdulhalim
Instantaneous high-resolution, wide-range focus tracking and a vibrometry system based on three-wavelength (3λ) parallel phase-shift polarization interferometry using three detectors per wavelength is presented. The system, implementing 3λ in-parallel three-phase-shift-interferometry channels for the first time, to the best of our knowledge, allows single-shot position tracking of motion profiles with extremely high velocities and vibration rates, long inter-step heights, and sub-nanometer scale accuracy...
February 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28198109/progenitors-in-peripheral-nerves-launch-heterotopic-ossification
#19
Elizabeth A Olmsted-Davis, Elizabeth A Salisbury, Diana Hoang, Eleanor L Davis, ZaWaunyka Lazard, Corinne Sonnet, Thomas A Davis, Jonathan A Forsberg, Alan R Davis
Studies presented here, using a murine model of bone morphogenetic protein type 2 (BMP2)-induced heterotopic ossification (HO) show that the protein initiates HO by signaling through progenitors in the endoneurium of peripheral nerves. In the mouse, these cells were identified in the endoneurium one day after BMP2 induction using antibody against phosphoSMAD (PS) 1, 5, and 8. Studies conducted in a tracking mouse that contains a tamoxifen-regulated Wnt1-Cre recombinase crossed with a td Tomato red (TR) reporter (Wnt1(CreErt) :Ai9Tm) confirmed their neural origin...
February 15, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28196404/a-p57-conditional-mutant-allele-that-allows-tracking-of-p57-expressing-cells
#20
Despoina Mademtzoglou, Sonia Alonso-Martin, Ted Hung-Tse Chang, Keren Bismuth, Bernadette Drayton-Libotte, Frédéric Aurade, Frédéric Relaix
p57(Kip2) (p57) is a maternally expressed imprinted gene regulating growth arrest which belongs to the CIP/KIP family of Cyclin-Dependent Kinase Inhibitors. While initially identified as a cell cycle arrest protein through inhibition of cyclin and cyclin-dependent kinase complexes, p57 activity has also been linked to differentiation, apoptosis, and senescence. In addition, p57 has recently been shown to be involved in tumorigenesis and cell fate decisions in stem cells. Yet, p57 function in adult tissues remains poorly characterized due to the perinatal lethality of p57 knock-out mice...
February 14, 2017: Genesis: the Journal of Genetics and Development
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