keyword
MENU ▼
Read by QxMD icon Read
search

stress ulcers

keyword
https://www.readbyqxmd.com/read/29450747/efficacy-of-bifidobacterium-breve-fermented-milk-in-maintaining-remission-of-ulcerative-colitis
#1
Katsuyoshi Matsuoka, Yukari Uemura, Takanori Kanai, Reiko Kunisaki, Yasuo Suzuki, Kaoru Yokoyama, Naoki Yoshimura, Toshifumi Hibi
BACKGROUND: Fermented milk products containing Bifidobacterium breve strain Yakult (BFM) may improve clinical status in ulcerative colitis (UC) patients. AIMS: To assess efficacy of BFM in maintaining remission in Japanese patients with quiescent UC. METHODS: This double-blind study (B-FLORA) enrolled 195 patients with quiescent UC, randomized to receive one pack of BFM fermented milk per day [Bifidobacterium breve strain Yakult (10 billion bacteria) and Lactobacillus acidophilus (1 billion bacteria)] (n = 98) or matching placebo (n = 97) for 48 weeks...
February 15, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29448206/regulation-of-jak2-stat3-and-nf-%C3%AE%C2%BAb-signal-transduction-pathways-veronica-polita-alleviates-dextran-sulfate-sodium-induced-murine-colitis
#2
Md Rashedunnabi Akanda, Hyeon-Hwa Nam, Weishun Tian, Anowarul Islam, Byung-Kil Choo, Byung-Yong Park
Ulcerative colitis (UC) is a major inflammatory bowel disease (IBD) has become a worldwide emergent disease. Veronica polita (VP) is a medicinal herb that has strong antioxidant and anti-inflammatory properties. In the present study, we studied the protective effect of VP on dextran sulfate sodium (DSS)-induced experimental colitis in mice. Phytochemical screening of VP extract demonstrated the presence of high total phenolic and flavonoid contents. Compared with the DSS group, VP significantly reduced clinical symptoms with less weight loss, bloody stool, shortening of the colon, and the severity of colitis was considerably inhibited as evidenced by the reduced disease activity index (DAI) and degree of histological damage in the colon and spleen...
February 12, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29438840/efficacy-and-safety-of-combined-low-doses-of-either-diclofenac-or-celecoxib-with-gabapentin-versus-their-single-high-dose-in-treatment-of-neuropathic-pain-in-rats
#3
Mohamed A Ibrahim, Walaa Yehia Abdelzaher, Remon R Rofaeil, Soha Abdelwahab
Neuropathic pain is a worldwide health problem with no consensus regarding its optimal therapy. This study compared the analgesic effect and gastric, hepatic, and renal safety of combined low doses of diclofenac and celecoxib with gabapentin versus their individual high doses in the treatment of neuropathic pain in rats. Left sciatic nerve ligation was used as neuropathic pain model. Rats were allocated into 7 groups (7 rats for each): sham control; model group (received vehicle); Gaba-group (received gabapentin (100 mg/kg /day); Diclo 10-group (received diclofenac (10 mg/kg); Cele 10-group (received celecoxib (10 mg/kg/day); Gaba + Diclo 5 (receivedgabapentin(100 mg/kg /day) plus diclofenac (5 mg/kg); Gaba + Cele 5 (received gabapentin (100 mg/kg/day) plus celecoxib (5 mg/kg))...
February 10, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29434945/peroxiredoxin-1-expression-in-active-ulcerative-colitis-mucosa-identified-by-proteome-analysis-and-involvement-of-thioredoxin-based-on-immunohistochemistry
#4
Kayo Horie, Tetuo Mikami, Tsutomu Yoshida, Yuichi Sato, Isao Okayasu
Ulcerative colitis (UC) is a chronic, relapsing, inflammatory bowel disease, and patients with long-standing UC are at high risk of developing colorectal cancer as a typical case of the organ-specific chronic inflammation-carcinoma sequence. Interactions between epithelial and stromal cells and alterations in a variety of stromal microenvironments have been demonstrated to have important roles in the carcinogenesis of UC-associated carcinoma. Therefore, the identification of proteins in the inflammatory microenvironment is important not only in the epithelium, however also in the stroma of UC inflammatory foci...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29404169/ranitidine-induced-anaphylaxis-in-a-patient-with-acute-copd-exacerbation
#5
İnsu Yılmaz, Murat Türk
Ranitidine is a well-tolerated H2-receptor antagonist commonly used in peptic ulcer treatment and stress ulcer prophylaxis. Anaphylaxis is rarely observed with ranitidine. We report the case of a patient who developed anaphylaxis after intravenous injection of ranitidine for acute COPD exacerbation. This article underlines the importance of awareness that in COPD acute exacerbation treatment, ranitidine, which is usually administered with methylprednisolone, also has anaphylaxis potential.
July 2017: Turkish thoracic journal
https://www.readbyqxmd.com/read/29403613/profile-of-peptic-ulcer-disease-and-its-risk-factors-in-arar-northern-saudi-arabia
#6
Afaf Shuaib Badi Albaqawi, Nagah Mohamed Abo El-Fetoh, Reem Faleh Abdullah Alanazi, Najah Salah Farhan Alanazi, Sara Emad Alrayya, Arwa Nughaymish Mulfi Alanazi, Shoug Zeid Trad Alenezi, Rehab Abdallah Alrkowi Alanazi, Anfal Muaddi Alshalan, Omar Tabaan Alenezi, Wafaa Mohamed Bakr Ali
Background: Peptic ulcer disease is a multifactorial health problem, and its prevalence and risk factors have changed considerably within the past century. Objective: To determine the prevalence of peptic ulcer among the population of Arar city and to identify risk factors for peptic ulcer and to estimate their relative impact on ulcer incidence. Methods: A cross-sectional study was carried out on the population of Arar city, Northern Saudi Arabia from November 01, 2016 to April 30, 2017...
November 2017: Electronic Physician
https://www.readbyqxmd.com/read/29402807/recent-advances-and-future-opportunities-to-address-challenges-in-offloading-diabetic-feet-a-mini-review
#7
Ryan T Crews, Abagayle L King, Sai V Yalla, Noah J Rosenblatt
Diabetic foot ulcers (DFU) are a substantial dilemma for geriatric individuals with diabetes. The breakdown in tissue associated with DFU is typically a result of repetitive cycles of physical stress placed on the feet during weight-bearing activity. Accordingly, a key tenet in healing as well as preventing DFU is the use of offloading footwear to redistribute physical stress away from high stress locations such as bony prominences. Over the last several years there has been a substantial amount of effort directed at better understanding and implementing the practice of offloading...
January 16, 2018: Gerontology
https://www.readbyqxmd.com/read/29402605/botulinum-toxin-b-suppresses-the-pressure-ulcer-formation-in-cutaneous-ischemia-reperfusion-injury-mouse-model-possible-regulation-of-oxidative-and-endoplasmic-reticulum-stress
#8
Akiko Sekiguchi, Sei-Ichiro Motegi, Akihiko Uchiyama, Akihito Uehara, Chisako Fujiwara, Sahori Yamazaki, Buddhini Perera, Hideharu Nakamura, Sachiko Ogino, Yoko Yokoyama, Ryoko Akai, Takao Iwawaki, Osamu Ishikawa
BACKGROUND: We previously identified that botulinum toxin A (BTX-A) suppressed pressure ulcer (PU) formation after cutaneous ischemia-reperfusion (I/R) injury; however, regulation of cutaneous I/R-induced oxidative and endoplasmic reticulum (ER) stress by BTX-B was not investigated. Additionally, the efficacy of BTX-B injection has never been examined. OBJECTIVE: Objective was to assess the effects of BTX-B on the formation of PU by cutaneous I/R injury, and the regulation of oxidative and ER stress in I/R injury by BTX-B...
February 2, 2018: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29401402/potential-of-lactobacillus-plantarum-zdy2013-and-bifidobacterium-bifidum-wbin03-in-relieving-colitis-by-gut-microbiota-immune-and-anti-oxidative-stress
#9
Yuanyuan Wang, Yilin Guo, Hui Chen, Hua Wei, Cuixiang Wan
Ulcerative colitis (UC) is an inflammatory bowel disease that is difficult to cure with rising incidence in recent decades. Probiotics have become a new strategy for the UC treatment. In this study, we chose two new multi-source probiotic, L. plantarum ZDY2013 from acid beans, B. bifidum WBIN03 from infant feces, and their mixture, to investigate the anti-inflammatory and antioxidant effect on the H2O2-induced HT-29 cell oxidation damaged model and dextran sodium sulfate (DSS)-induced colitis mice. Compared with the model group, the general relative indexes results showed L...
February 5, 2018: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/29399316/adjunct-use-of-low-level-laser-therapy-on-the-treatment-of-necrotizing-ulcerative-gingivitis-a-case-report
#10
Seda Sevinç Özberk, Hasan Gündoğar, Süleyman Ziya Şenyurt, Kamile Erciyas
Necrotizing ulcerative gingivitis (NUG) is a microbial disease of the gingiva in the context of an impaired host response. This form of gingivitis is relatively rare. NUG is an infection characterized by gingival necrosis presenting as "punched-out" papillae, spontaneous bleeding, pain, oral malodor, and pseudomembrane formation. The primary predisposing factors are bacterial plaque and an inadequate diet, but smoking and psychological stress may also affect the disease severity. NUG is associated with a characteristic bacterial flora, which includes fusiform bacteria, spirochetes, and Prevotella intermedia...
2018: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29397595/-the-impact-of-stress-and-personality-on-resilience-of-patients-with-ulcerative-colitis
#11
W Liu, J Wang, H Wang, X Y Chen, J S Li
Objective: To study relevant factors that influence psychological resilience in patients with ulcerative colitis(UC), especially the role of perceived stress and personality. Methods: Patients with UC were recruited from January 2015 to December 2016 in the First Hospital of Zhengzhou University. Education levels, income, duration of disease, Mayo score and disease phenotype according to Montreal classification were collected. Resilience was measured using Connor-Davidson resilience scale (CD-RISC). Perceived stress was measured by perceived stress scale (PSS)...
February 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29397336/artesunate-affords-protection-against-aspirin-induced-gastric-injury-by-targeting-oxidative-stress-and-proinflammatory-signaling
#12
Sneh Verma, Vijay L Kumar
BACKGROUND: Prolonged use of aspirin, a commonly prescribed non steroidal anti-inflammatory drug, is well known to produce gastrointestinal toxicity which could be minimized by various anti-secretory agents. The present study was carried out to evaluate the protective effect of artesunate against aspirin induced gastric injury in rats. METHODS: Gastric injury was induced in fasted Wistar rats by oral administration of aspirin. The effect of 50 and 150 mg/kg of artesunate was studied on macroscopic changes, gastric secretions, histology, oxidative stress and inflammatory markers in the stomach tissue after 5 h of induction of gastric injury...
June 15, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29388698/silibinin-protects-human-endothelial-cells-from-high-glucose-induced-injury-by-enhancing-autophagic-response
#13
Aysa Rezabakhsh, Farzaneh Fathi, Hesam Bagheri Saghaei, Hassan Malekinejad, Azadeh Montaseri, Reza Rahbarghazi, Alireza Garjani
Silibin, a flavonoid from the seeds of Silybum marianum (L.) Gaertn. (Asteraceae) has been reported to produce curative properties in diabetes. Autophagy is generated by a vast array of insults for removal of damaged proteins and organelles from the cell. Inadequate autophagy promotes endothelial cells dysfunction and delays in diabetic ulcers recovery. We hypothesized that silibinin could protect endothelial cells against high glucose-induced damage by engaging autophagic responses. HUVECs viability was evaluated by MTT assay...
February 1, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29386234/practice-guidelines-for-clinical-microbiology-laboratories-mycobacteria
#14
REVIEW
Betty A Forbes, Geraldine S Hall, Melissa B Miller, Susan M Novak, Marie-Claire Rowlinson, Max Salfinger, Akos Somoskövi, David M Warshauer, Michael L Wilson
Mycobacteria are the causative organisms for diseases such as tuberculosis (TB), leprosy, Buruli ulcer, and pulmonary nontuberculous mycobacterial disease, to name the most important ones. In 2015, globally, almost 10 million people developed TB, and almost half a million patients suffered from its multidrug-resistant form. In 2016, a total of 9,287 new TB cases were reported in the United States. In 2015, there were 174,608 new case of leprosy worldwide. India, Brazil, and Indonesia reported the most leprosy cases...
April 2018: Clinical Microbiology Reviews
https://www.readbyqxmd.com/read/29374489/stress-ulcer-prophylaxis-in-intensive-care-unit-patients-receiving-enteral-nutrition-a-systematic-review-and-meta-analysis
#15
Hui-Bin Huang, Wei Jiang, Chun-Yao Wang, Han-Yu Qin, Bin Du
BACKGROUND: Pharmacologic stress ulcer prophylaxis (SUP) is recommended in critically ill patients with high risk of stress-related gastrointestinal (GI) bleeding. However, as to patients receiving enteral feeding, the preventive effect of SUP is not well-known. Therefore, we performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of pharmacologic SUP in enterally fed patients on stress-related GI bleeding and other clinical outcomes. METHODS: We searched PubMed, Embase, and the Cochrane database from inception through 30 Sep 2017...
January 28, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29339218/protective-effect-of-patchoulene-epoxide-against-ethanol-induced-gastric-ulcer-in-rats-influence-on-oxidative-stress-inflammation-and-apoptosis
#16
Jiali Liang, Yaoxing Dou, Xue Wu, Huilin Li, Jiazhen Wu, Qionghui Huang, Dandan Luo, Tiegang Yi, Yuhong Liu, Ziren Su, Jianping Chen
Patchoulene epoxide (PAO), a tricyclic sesquiterpene isolated from the long-strored patchouli oil, has been demonstrated the anti-inflammatory activity in vivo based on our previous study. However, the gastroprotective effect of PAO still remains unknown. Therefore, in the present study, ethanol-induced gastric ulcer in rats was carried out to evaluate the anti-ulcerogenic activity of PAO and to elucidate the potential mechanisms that involved. According to our results, macroscopic examination revealed that pre-treatment with PAO signficantly reduced ethanol-induced gastric ulcer areas as compared with the vehicle group, which was also supported by histological evaluation...
January 12, 2018: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29321041/effects-of-stress-ulcer-prophylaxis-in-adult-icu-patients-receiving-renal-replacement-therapy-sup-icu-renal-siren-study-protocol-for-a-pre-planned-observational-study
#17
Joerg C Schefold, Anders Perner, Theis Lange, Jørn Wetterslev, Matt P Wise, Mark Borthwick, Stepani Bendel, Frederik Keus, Anne Berit Guttormsen, Søren Marker, Mette Krag, Morten Hylander Møller
BACKGROUND: Proton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit. Patients with acute kidney injury requiring renal replacement therapy (RRT) are at high risk of gastrointestinal bleeding as (pre-)uremia induces coagulopathy through effects on platelets and coagulation cascades. No high-quality randomized clinical trials have previously assessed the benefits and harms of prophylactic proton pump inhibitor use in this high-risk population of adult critically ill patients...
January 10, 2018: Trials
https://www.readbyqxmd.com/read/29278022/recurrent-aphthous-ulceration-a-review-of-potential-causes-and-novel-treatments
#18
Sami Kameel Saikaly, Tanya Siham Saikaly, Lara Elizabeth Saikaly
Purpose of Article: This review examines studies published between May 2012 and May 2017 with a specific interest in potential recurrent aphthous ulceration (RAU) etiologies and treatment modalities/efficacy, including topical treatments, systemic regimens, vitamin repletion, and laser therapy, among others. MATERIALS AND METHODS: PubMed MEDLINE and Cochrane Database of Systematic Reviews were searched using various combinations of: 'aphthous', 'ulcer', and 'treatment'. The titles and abstracts from the initial literature search were appraised to identify articles for full review, and reference sections from each article were searched manually for relevant publications...
December 26, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29277718/effect-of-allantoin-on-experimentally-induced-gastric-ulcers-pathways-of-gastroprotection
#19
Dayane Moreira da Silva, José Luís Rodrigues Martins, Danillo Ramos de Oliveira, Iziara Ferreira Florentino, Daiany Priscilla Bueno da Silva, Fernanda Cristina Alcântara Dos Santos, Elson Alves Costa
Gastric ulcer affects people worldwide, and its inefficacy and recurrence have fueled the search for new therapeutic strategies. Despite the well-known use of allantoin in medicines and cosmetic products, its effect has not yet been studied with regard to gastric ulcer. Hence, the aim of the present study was to explore the pharmaco-mechanistic efficacy of allantoin against commonly harmful agents that cause injuries to the stomach. Ethanol, indomethacin, and stress-induced gastric ulcer models were adopted, in addition to pylorus ligature, a quantification of vascular permeability, glutathione (GSH), gastric adhered mucus, prostaglandin (PGE2), pro-inflammatory cytokines levels, myeloperoxidase (MPO), and catalase (CAT) activities...
December 22, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29258248/pomegranate-punica-granatum-juice-shows-antioxidant-activity-against-cutaneous-leishmaniasis-induced-oxidative-stress-in-female-balb-c-mice
#20
Badriah Alkathiri, Manal F El-Khadragy, Dina M Metwally, Ebtesam M Al-Olayan, Muhammed A Bakhrebah, Ahmed E Abdel Moneim
Leishmania species are parasites that multiply within phagocytes and cause several clinical diseases characterized by single or multiple ulcerations. One of the complications that can induce tissue damage and the resulting scars is caused by secondary bacterial infections. Studies to find new, effective, and safe oral drugs for treating leishmaniasis are being conducted since several decades, owing to the problems associated with the use of antimonials available. Previously, the antiparasitic and antioxidant properties of Punica granatum (pomegranate, P...
December 18, 2017: International Journal of Environmental Research and Public Health
keyword
keyword
111313
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"