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https://www.readbyqxmd.com/read/29440881/immediate-synergistic-effect-of-a-trunk-orthosis-with-joints-providing-resistive-force-and-an-ankle-foot-orthosis-on-hemiplegic-gait
#1
Junji Katsuhira, Sumiko Yamamoto, Nodoka Machida, Yuji Ohmura, Masako Fuchi, Mizuho Ohta, Setsuro Ibayashi, Arito Yozu, Ko Matsudaira
Purpose: The synergistic effects of a trunk orthosis and an ankle-foot orthosis (AFO) in stroke patients with a hemiplegic gait are unclear. We previously developed a trunk orthosis with joints providing resistive force (TORF) to modify malalignment of the trunk and pelvis and confirmed its positive effects in stroke patients during level walking without an AFO. The aim of the present study was to determine if this trunk orthosis and an AFO have synergistic effects during level walking in community-dwelling patients with chronic stroke...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29428506/8-year-retrospective-analysis-of-intravenous-arginine-therapy-for-acute-metabolic-strokes-in-pediatric-mitochondrial-disease
#2
Rebecca D Ganetzky, Marni J Falk
BACKGROUND: Intravenous (IV) arginine has been reported to ameliorate acute metabolic stroke symptoms in adult patients with Mitochondrial Encephalopathy with Lactic Acidosis and Stroke-like Episodes (MELAS) syndrome, where its therapeutic benefit is postulated to result from arginine acting as a nitric oxide donor to reverse vasospasm. Further, reduced plasma arginine may occur in mitochondrial disease since the biosynthesis of arginine's precursor, citrulline, requires ATP. Metabolic strokes occur across a wide array of primary mitochondrial diseases having diverse molecular etiologies that are likely to share similar pathophysiologic mechanisms...
February 2, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29419537/modification-of-a-ventricular-assistance-device-for-a-hemiplegic-left-ventricular-assist-device-patient
#3
Rahatullah Muslem, Yunus C Yalçin, Kadir Caliskan, Cees van der Heiden, Hans van Rhijn, Ad J J C Bogers, Olivier C Manintveld
Neurologic events occur in up to 18% of patients with continuous-flow left ventricular assist devices (LVAD) and is associated with significant morbidity and mortality. The current form of the LVAD equipment is not suited to serve patients who are impaired by a stroke. By creating an assistance device for the LVAD equipment, we have been able to greatly improve the quality of life and self-dependence of a hemiplegic LVAD patient.
February 6, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29395663/atp1a3-related-epileptic-encephalopathy-responding-to-ketogenic-diet
#4
Tommaso Schirinzi, Federica Graziola, Raffaella Cusmai, Lucia Fusco, Francesco Nicita, Mirella Elia, Lorena Travaglini, Enrico Bertini, Paolo Curatolo, Federico Vigevano, Alessandro Capuano
BACKGROUND: Alternating Hemiplegia of Childhood (AHC) is a rare neurological disease caused by mutations in ATP1A3 gene codifying for alpha3 subunit of Na+-K+ ATPase pump. Repeated and transient attacks of hemiplegia, usually affecting one side of the body or the other, or both sides of the body at once, are the core features of AHC. Monocular nystagmus, other abnormalities in ocular movements, dystonic posturing and epilepsy are commonly associated to AHC. However, the spectrum of ATP1A3 related diseases is still expanding and new phenotypes have been reported...
January 26, 2018: Brain & Development
https://www.readbyqxmd.com/read/29390330/musculoskeletal-ultrasound-guided-physical-therapy-in-hemiplegic-shoulder-pain-a-care-compliant-case-report
#5
Jingjing Zhang, Yan Li, Hongxing Wang
RATIONALE: The use of musculoskeletal ultrasound (MU) method in the diagnosis of shoulder pain and injury and guidance of injection and pain blocking has been established. However, the treatment of posthemiplegic shoulder pain (HSP) with MU-guided precise physical therapy has not been reported. PATIENT CONCERNS: Here, we present the first case report of a 64-year-old man with a right basal ganglia hemorrhage. Left side shoulder pain remained unbearable, which seriously affected sleep and shoulder-related activities...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389721/quantitative-assessment-of-knee-progression-angle-during-gait-in-children-with-cerebral-palsy
#6
Jon R Davids, Nina Q Cung, Robin Pomeroy, Brooke Schultz, Leslie Torburn, Vedant A Kulkarni, Sean Brown, Anita M Bagley
BACKGROUND: Abnormal hip rotation is a common deviation in children with cerebral palsy (CP). Clinicians typically assess hip rotation during gait by observing the direction that the patella points relative to the path of walking, which is referred to as the knee progression angle (KPA). Two kinematic methods for calculating the KPA are compared with each other. Video-based qualitative assessment of KPA is compared with the quantitative methods to determine reliability and validity. METHODS: The KPA was calculated by both direct and indirect methods for 32 typically developing (TD) children and a convenience cohort of 43 children with hemiplegic type CP...
January 31, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29384561/ocular-dipping-in-a-patient-with-hemiplegic-migraine
#7
Iga N Gray, Ana G Cristancho, Daniel J Licht, Grant T Liu
A 5-year-old girl presented with acute, rapidly progressive encephalopathy following minor head trauma and was found to have ocular dipping. Her encephalopathy was secondary to a channelopathy caused by a CACNA1A mutation. This is the first reported case of ocular dipping in an encephalopathic child with CACNA1A-confirmed hemiplegic migraine. [J Pediatr Ophthalmol Strabismus. 2018;55:e4-e6.].
January 31, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29378582/a-novel-one-arm-motorized-walker-for-hemiplegic-stroke-survivors-a-feasibility-study
#8
Ki-Hun Cho, SeungHyeon Pyo, Gi-Su Shin, Sung-Duk Hong, Se-Han Lee, DongGeon Lee, SunHae Song, GyuChang Lee
BACKGROUND: A hemiplegic stroke survivor with a moderate to severe gait disturbance may have difficulty walking using a one-arm walker. This study aimed to test the safety and feasibility of a prototype one-arm motorized walker that uses a power-driven device to provide gait assistance to hemiplegic stroke survivors with moderate to severe gait disturbances. METHODS: A one-arm motorized walker with a power-driven device was developed and tested with respect to 10 distinct variables, including weight, degrees of freedom, handle, handle substitution function, two-sided use function, variable handle height, redirecting function, electric moving parts through the handle control, brake function using the handle control, folding chairs, and design stability...
January 30, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29376886/scalp-acupuncture-plus-low-frequency-rtms-promotes-repair-of-brain-white-matter-tracts-in-stroke-patients-a%C3%A2-dti-study
#9
Ning Zhao, Jingna Zhang, Mingguo Qiu, Chunrong Wang, Yun Xiang, Hui Wang, Jingwen Xie, Shu Liu, Jing Wu
To study the clinical effects of scalp acupuncture plus low frequency rTMS in hemiplegic stroke patients. A total of 28 hemiplegic stroke patients were recruited and randomly assigned to the experimental group (scalp acupuncture + low frequency rTMS + routine rehabilitation treatment) or the control group (scalp acupuncture + routine rehabilitation treatment). All patients received a diffusion tensor imaging examination on the day of admission and on the fourteenth day. Compared with pre-treatment, the upper limb motor function score and ability of daily life score increased significantly in the two groups, and motor function improvement was much greater in the experimental group...
2018: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/29366381/an-atypical-rett-syndrome-phenotype-due-to-a-novel-missense-mutation-in-cacna1a
#10
Madison V Epperson, Michael E Haws, Shannon M Standridge, Donald L Gilbert
BACKGROUND: Some typical and atypical Rett syndrome patients lack known genetic mutations. Mutations in the P/Q type calcium channel CACNA1A have been implicated in epileptic encephalopathy, familial hemiplegic migraine, episodic ataxia 2, and spinocerebellar ataxia 6, but not Rett syndrome. Patient Description: The authors describe a female patient with developmental regression and a de novo, likely pathogenic mutation in CACNA1A who meets 3 of 4 main criteria (stereotypic hand movements, loss of purposeful hand movements, gait disturbance), and 6 of 11 supportive criteria (impaired sleep, abnormal tone, vasomotor disturbance, scoliosis, growth retardation, and screaming spells) for atypical Rett syndrome...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29357466/backward-walking-highlights-gait-asymmetries-in-children-with-cerebral-palsy
#11
Germana Cappellini, Francesca Sylos-Labini, Michael J MacLellan, Annalisa Sacco, Daniela Morelli, Francesco Lacquaniti, Yury Ivanenko
To investigate how early injuries to developing motor regions of the brain affect different forms of gait, we compared the spatiotemporal locomotor patterns during forward (FW) and backward (BW) walking in children with cerebral palsy (CP). Bilateral gait kinematics and EMG activity of 11 pairs of leg muscles were recorded in 14 children with CP (9 diplegic, 5 hemiplegic, 3.0-11.1 yrs) and 14 typically developing (TD) children (3.3-11.8 yrs). During BW, children with CP showed a significant increase of gait asymmetry in foot trajectory characteristics and limb intersegmental coordination...
December 20, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29357280/effectiveness-of-neuromuscular-electrical-stimulation-on-lower-limb-hemiplegic-patients-following-chronic-stroke-a-systematic-review
#12
REVIEW
Zhongqiu Hong, Minghong Sui, Zhiqiang Zhuang, Huihua Liu, Xiuyuan Zheng, Chuanping Cai, Dongmei Jin
OBJECTIVE: To investigate the effectiveness of neuromuscular electrical stimulation (NMES) with or without other interventions in improving lower limb activity after chronic stroke. DATA SOURCE: Electronic databases including PubMed, EMBase, Cochrane Library, PEDro (Physiotherapy Evidence Database) and PsycINFO were searched from the inception to January, 2017. STUDY SELECTION: We selected the randomized controlled trials (RCTs) involving chronic stroke survivors with lower limb dysfunction and comparing NMES or combined with other interventions with control of no electrical-stimulated treatment...
January 18, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29354911/-clinical-efficacy-of-electroacupuncture-combined-with-motor-imagery-therapy-on-hemiplegic-cerebral-infarction
#13
Feng Zhu, Jianyun Gao, Run Gao, Yikang He, Li Liu, Bingwei Ai
OBJECTIVE: To explore the effects of electroacupuncture (EA) combined with motor imagery therapy on motor function and activity of daily living in patients with hemiplegic cerebral infarction. METHODS: Ninety patients with hemiplegic cerebral infarction were randomly divided into a rehabilitation group, an EA group and a comprehensive group, 30 patients in each one. The patients in the rehabilitation group were treated with regular care, medication and rehabilitation training; based on the rehabilitation group, the patients in the EA group were treated mainly with electroacupuncture at Baihui (GV 20), Dingnieqianxiexian (MS 6), Dingniehouxiexian (MS 7), Jianyu (LI 15), Waiguan (TE 5), Fengshi (GB 31) and Sanyinjiao (SP 6); with the arrival of qi...
September 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29354588/disruption-of-the-corticoreticular-tract-in-pediatric-patients-with-trunk-instability-a-diffusion-tensor-tractography-study
#14
Su Min Son, So Min Shin
The authors report the diffusion tensor tractography (DTT) findings of three pediatric patients with gait dysfunction and corticoreticular tract (CRT) disruption. All three patients showed unilateral trunk instability, but they did not show any spasticity or weakness of the distal extremities. Clinical evaluation of trunk instability using a Trunk Control Measurement Scale (TCMS) revealed that the more affected side had a lower score than the contralateral side. DTT showed disrupted CRTs in hemispheres contralateral to the hemiparetic sides, which were associated with unilateral proximal instability, although conventional MRI showed no abnormal lesion explaining the hemiplegic symptom...
December 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29343472/clinical-spectrum-of-hemiplegic-migraine-and-chances-of-finding-a-pathogenic-mutation
#15
Nadine Pelzer, Joost Haan, Anine H Stam, Lisanne S Vijfhuizen, Stephany C Koelewijn, Amber Smagge, Boukje de Vries, Michel D Ferrari, Arn M J M van den Maagdenberg, Gisela M Terwindt
OBJECTIVE: To investigate whether the clinical characteristics of patients with hemiplegic migraine with and without autosomal dominant mutations in CACNA1A, ATP1A2, or SCN1A differ, and whether the disease may be caused by mutations in other genes. METHODS: We compared the clinical characteristics of 208 patients with familial (n = 199) or sporadic (n = 9) hemiplegic migraine due to a mutation in CACNA1A, ATP1A2, or SCN1A with those of 73 patients with familial (n = 49) or sporadic (n = 24) hemiplegic migraine without a mutation in these genes...
January 17, 2018: Neurology
https://www.readbyqxmd.com/read/29329286/is-the-proportional-recovery-rule-applicable-to-the-lower-limb-after-a-first-ever-ischemic-stroke
#16
Janne M Veerbeek, Caroline Winters, Erwin E H van Wegen, Gert Kwakkel
OBJECTIVE: To investigate (a) the applicability of the proportional recovery rule of spontaneous neurobiological recovery to motor function of the paretic lower extremity (LE); and (b) the presence of fitters and non-fitters of this prognostic rule poststroke. When present, the clinical threshold for fitting nor non-fitting would be determined, as well as within-subject generalizability to the paretic upper extremity (UE). METHODS: Prospective cohort study in which the Fugl-Meyer Assessment (FMA)-LE and FMA-UE were measured <72 hours and 6 months poststroke...
2018: PloS One
https://www.readbyqxmd.com/read/29304114/comparison-of-calf-muscle-architecture-between-asian-children-with-spastic-cerebral-palsy-and-typically-developing-peers
#17
Ying Chen, Lu He, Kaishou Xu, Jinling Li, Buyun Guan, Hongmei Tang
OBJECTIVE: To compare the muscle thickness, fascicle length, and pennation angle of the gastrocnemius, soleus, and tibialis anterior between Asian children with spastic cerebral palsy (CP) and typically developing (TD) peers. METHODS: This cross-sectional study involved a total of 72 children with hemiplegic CP (n = 24), and diplegic CP (n = 24) and their TD peers (n = 24). Muscle architecture was measured at rest using ultrasound. Clinical measures included gross motor function and a modified Ashworth scale...
2018: PloS One
https://www.readbyqxmd.com/read/29282739/clinical-acceptability-of-the-sense_assess%C3%A2-kids-children-and-youth-perspectives
#18
Susan Taylor, Belinda McLean, Eve Blair, Leeanne Mary Carey, Jane Valentine, Sonya Girdler, Catherine Elliott
BACKGROUND: The sense_assess© kids is a standardised, norm-referenced assessment designed to measure the functional somatosensation capacity of the upper limb of children with cerebral palsy. The objective of the current study was to determine if the sense_assess© kids was clinically acceptable to children and youth. METHODS: A questionnaire was completed by participants following administration of the sense_assess© kids by a trained occupational therapist. Twenty-six children with spastic hemiplegic cerebral palsy (aged 6-15 years six months; mean 10 years eight months; 16 boys) were recruited...
December 28, 2017: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/29243508/the-effectiveness-of-hydrokinesiotherapy-on-postural-balance-of-hemiplegic-patients-after-stroke-a-systematic-review-and-meta-analysis
#19
Georgia Iatridou, Henrietta-Syngliti Pelidou, Dimitrios Varvarousis, Alexandra Stergiou, Alexander Beris, Panagiotis Givissis, Avraam Ploumis
OBJECTIVE: To summarize evidence on the effects of hydrokinesiotherapy (HT) on postural balance in hemiplegic patients after stroke and compare them with conventional land therapy. DATA SOURCES: A literature search until October 2017 was conducted on CINAHL, PubMed, Cochrane EBM Reviews, Cochrane Clinical Trials, DARE, MEDLINE, Physiotherapy Evidence Database (PEDro), PsycInfo and Rehabilitation and Sports Medicine Source. REVIEW METHODS: Only randomized controlled trials with pre-intervention and post-intervention assessment on postural control have been included...
December 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29238181/the-link-between-weight-shift-asymmetry-and-gait-disturbances-in-chronic-hemiparetic-stroke-patients
#20
Andrzej Szopa, Małgorzata Domagalska-Szopa, Anetta Lasek-Bal, Amadeusz Żak
Introduction: While the asymmetry of body posture and the asymmetrical nature of hemiparetic gait in poststroke (PS) patients are well documented, the role of weight shift asymmetry in gait disorders after stroke remains unclear. Objective: We examined the association of weight-bearing asymmetry (WBA) between paretic and nonparetic lower limbs during quiet standing with the degree of deviation of hemiplegic gait from normal gait evaluated by the Gillette Gait Index (GGI) incorporating 16 distinct clinically important kinematic and temporal parameters in chronic PS patients...
2017: Clinical Interventions in Aging
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