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Hypertrophic training

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https://www.readbyqxmd.com/read/29621305/biomarkers-associated-with-low-moderate-and-high-vastus-lateralis-muscle-hypertrophy-following-12-weeks-of-resistance-training
#1
Christopher B Mobley, Cody T Haun, Paul A Roberson, Petey W Mumford, Wesley C Kephart, Matthew A Romero, Shelby C Osburn, Christopher G Vann, Kaelin C Young, Darren T Beck, Jeffrey S Martin, Christopher M Lockwood, Michael D Roberts
We sought to identify biomarkers which delineated individual hypertrophic responses to resistance training. Untrained, college-aged males engaged in full-body resistance training (3 d/wk) for 12 weeks. Body composition via dual x-ray absorptiometry (DXA), vastus lateralis (VL) thickness via ultrasound, blood, VL muscle biopsies, and three-repetition maximum (3-RM) squat strength were obtained prior to (PRE) and following (POST) 12 weeks of training. K-means cluster analysis based on VL thickness changes identified LOW [n = 17; change (mean±SD) = +0...
2018: PloS One
https://www.readbyqxmd.com/read/29565774/muscle-hypertrophy-following-blood-flow-restricted-low-force-isometric-electrical-stimulation-in-rat-tibialis-anterior-role-for-muscle-hypoxia
#2
Toshiaki Nakajima, Seiichiro Koide, Tomohiro Yasuda, Takaaki Hasegawa, Tatsuya Yamasoba, Syotaro Obi, Shigeru Toyoda, Fumitaka Nakamura, Teruo Inoue, David C Poole, Yutaka Kano
Low force exercise training with blood flow restriction (BFR) elicits muscle hypertrophy. We investigated the effects of microvascular hypoxia (i.e., low microvascular O2 partial pressures, PmvO2 ) during contractions on hypertrophic signaling, growth response and key muscle adaptations for increasing exercise capacity. Wistar rats were fitted with a cuff placed around the upper thigh and inflated to restrict limb blood flow. Low force isometric contractions (30 Hz) were evoked via electrical stimulation of the tibialis anterior (TA) nerve...
March 22, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29506814/a-simulated-training-model-for-laparoscopic-pyloromyotomy-is-3d-printing-the-way-of-the-future
#3
Andrew Williams, Morgan McWilliam, James Ahlin, Jacob Davidson, Mackenzie A Quantz, Andreana Bütter
BACKGROUND: Hypertrophic pyloric stenosis (HPS) is a common neonatal condition treated with open or laparoscopic pyloromyotomy. 3D-printed organs offer realistic simulations to practice surgical techniques. The purpose of this study was to validate a 3D HPS stomach model and assess model reliability and surgical realism. METHODS: Medical students, general surgery residents, and adult and pediatric general surgeons were recruited from a single center. Participants were videotaped three times performing a laparoscopic pyloromyotomy using box trainers and 3D-printed stomachs...
February 8, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29447936/inducing-hypertrophic-effects-of-type-i-skeletal-muscle-fibers-a-hypothetical-role-of-time-under-load-in-resistance-training-aimed-at-muscular-hypertrophy
#4
Jozo Grgic, Jan Homolak, Pavle Mikulic, Javier Botella, Brad J Schoenfeld
An emerging body of evidence is starting to suggest that the hypertrophy of skeletal muscle fibers might be load specific. In other words, it may be that resistance training with high loads (i.e., ≥60% of 1 repetition maximum [RM]) emphasizes a greater growth of type II muscle fibers, while resistance training with low loads (i.e., <60% of 1RM) might primarily augment hypertrophy of type I muscle fibers. Type I and type II muscle fibers possess certain distinct characteristics, with type II muscle fibers having faster calcium kinetics, faster shortening velocities, and ability to generate more power than type I muscle fibers...
March 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29414855/recent-perspectives-regarding-the-role-of-dietary-protein-for-the-promotion-of-muscle-hypertrophy-with-resistance-exercise-training
#5
REVIEW
Tanner Stokes, Amy J Hector, Robert W Morton, Chris McGlory, Stuart M Phillips
Skeletal muscle supports locomotion and serves as the largest site of postprandial glucose disposal; thus it is a critical organ for physical and metabolic health. Skeletal muscle mass is regulated by the processes of muscle protein synthesis (MPS) and muscle protein breakdown (MPB), both of which are sensitive to external loading and aminoacidemia. Hyperaminoacidemia results in a robust but transient increase in rates of MPS and a mild suppression of MPB. Resistance exercise potentiates the aminoacidemia-induced rise in MPS that, when repeated over time, results in gradual radial growth of skeletal muscle (i...
February 7, 2018: Nutrients
https://www.readbyqxmd.com/read/29338015/exercise-induced-circulating-microrna-changes-in-athletes-in-various-training-scenarios
#6
Martin Horak, Filip Zlamal, Robert Iliev, Jan Kucera, Jan Cacek, Lenka Svobodova, Zuzana Hlavonova, Tomas Kalina, Ondrej Slaby, Julie Bienertova-Vasku
BACKGROUND: The aim of the study was to compare selected extracellular miRNA levels (miR-16, miR-21, miR-93 and miR-222 with the response to 8-week-long explosive strength training (EXPL), hypertrophic strength training (HYP) and high-intensity interval training (HIIT). METHODS: 30 young male athletes of white European origin (mean age: 22.5 ± 4.06 years) recruited at the Faculty of Sports Studies of Masaryk University were enrolled in this study. The study participants were randomly assigned to three possible training scenarios: EXPL, HYP or HITT and participated in 8-week-long program in given arm...
2018: PloS One
https://www.readbyqxmd.com/read/29330460/enhanced-skeletal-muscle-ribosome-biogenesis-yet-attenuated-mtorc1-and-ribosome-biogenesis-related-signalling-following-short-term-concurrent-versus-single-mode-resistance-training
#7
Jackson J Fyfe, David J Bishop, Jonathan D Bartlett, Erik D Hanson, Mitchell J Anderson, Andrew P Garnham, Nigel K Stepto
Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training versus RT alone. Twenty-three males underwent eight weeks of RT, either performed alone (RT group, n = 8), or combined with either high-intensity interval training (HIT+RT group, n = 8), or moderate-intensity continuous training (MICT+RT group, n = 7)...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29306449/chronic-exercise-induces-pathological-left-ventricular-hypertrophy-in-adrenaline-deficient-mice
#8
Priscila Mendes, Raquel Martinho, Sara Leite, Leonardo Maia-Moço, Adelino F Leite-Moreira, André P Lourenço, Mónica Moreira-Rodrigues
Adrenaline-deficient phenylethanolamine-N-methyltransferase-knockout mice (Pnmt-KO) have concentric heart remodeling and though their resting blood pressure is normal, it becomes higher during acute exercise. The aim of this study was to evaluate cardiac morphological, functional and molecular alterations after chronic exercise in adrenaline-deficient mice. Genotypes at the Pnmt locus were verified by polymerase chain reaction (PCR) of ear samples of Pnmt-KO and wild-type (WT) mice. These mice were submitted to chronic exercise training during 6weeks...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29283292/morphological-molecular-and-hormonal-adaptations-to-early-morning-versus-afternoon-resistance-training
#9
Milan Sedliak, Michal Zeman, Gabriel Buzgó, Jan Cvecka, Dusan Hamar, Eugen Laczo, Monika Okuliarova, Marian Vanderka, Tomas Kampmiller, Keijo Häkkinen, Juha P Ahtiainen, Juha J Hulmi, Tormod S Nilsen, Håvard Wiig, Truls Raastad
It has been clearly established that maximal force and power is lower in the morning compared to noon or afternoon hours. This morning neuromuscular deficit can be diminished by regularly training in the morning hours. However, there is limited and contradictory information upon hypertrophic adaptations to time-of-day-specific resistance training. Moreover, no cellular or molecular mechanisms related to muscle hypertrophy adaptation have been studied with this respect. Therefore, the present study examined effects of the time-of-day-specific resistance training on muscle hypertrophy, phosphorylation of selected proteins, hormonal concentrations and neuromuscular performance...
December 28, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29249978/prediction-of-scar-size-in-rats-six-months-after-burns-based-on-early-post-injury-polarization-sensitive-optical-frequency-domain-imaging
#10
Eli Kravez, Martin Villiger, Brett Bouma, Martin Yarmush, Zohar Yakhini, Alexander Golberg
Hypertrophic scars remain a major clinical problem in the rehabilitation of burn survivors and lead to physical, aesthetic, functional, psychological, and social stresses. Prediction of healing outcome and scar formation is critical for deciding on the best treatment plan. Both subjective and objective scales have been devised to assess scar severity. Whereas scales of the first type preclude cross-comparison between observers, those of the second type are based on imaging modalities that either lack the ability to image individual layers of the scar or only provide very limited fields of view...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29248842/group-wise-similarity-registration-of-point-sets-using-student-s-t-mixture-model-for-statistical-shape-models
#11
Nishant Ravikumar, Ali Gooya, Serkan Çimen, Alejandro F Frangi, Zeike A Taylor
A probabilistic group-wise similarity registration technique based on Student's t-mixture model (TMM) and a multi-resolution extension of the same (mr-TMM) are proposed in this study, to robustly align shapes and establish valid correspondences, for the purpose of training statistical shape models (SSMs). Shape analysis across large cohorts requires automatic generation of the requisite training sets. Automated segmentation and landmarking of medical images often result in shapes with varying proportions of outliers and consequently require a robust method of alignment and correspondence estimation...
February 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29246825/mohs-micrographic-surgery-and-dermatopathology-concordance-an-analysis-of-1421-mohs-cases-over-17-years
#12
Katarina Kesty, Omar P Sangueza, Barry Leshin, John G Albertini
BACKGROUND: The success of Mohs micrographic surgery depends on the surgeon's ability to correctly interpret intraoperative frozen sections. OBJECTIVE: This retrospective study analyzed the rate of concordance between Mohs surgeons and dermatopathologists in reading slides from Mohs surgery cases. METHODS: A dermatopathologist reviewed all the frozen sections and the corresponding Mohs map for every 30th Mohs case at a practice employing 6 different Mohs surgeons from 2001-2017...
December 13, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29234504/the-effects-of-low-intensity-blood-flow-restricted-exercise-compared-with-conventional-resistance-training-on-the-clinical-outcomes-of-active-uk-military-personnel-following-a-3-week-in-patient-rehabilitation-programme-protocol-for-a-randomized-controlled-feasibility
#13
Peter Ladlow, Russell J Coppack, Shreshth Dharm-Datta, Dean Conway, Edward Sellon, Stephen D Patterson, Alexander N Bennett
Background: A challenge for rehabilitation practitioners lies in designing optimal exercise programmes that facilitate musculoskeletal (MSK) adaptations whilst simultaneously accommodating biological healing and the safe loading of an injured limb. A growing body of evidence supports the use of resistance training at a reduced load in combination with blood flow restriction (BFR) to enhance hypertrophic and strength responses in skeletal muscle. In-patient rehabilitation has a long tradition in the UK Military, however, the efficacy of low intensity (LI) BFR training has not been tested in this rehabilitation setting...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29228435/review-of-recent-advances-in-the-management-of-hypertrophic-cardiomyopathy
#14
Y Cao, P-Y Zhang
Hypertrophic cardiomyopathy (HCM) is a complex but common monogenic cardiovascular disorder characterized by unexplained non dilated left ventricular (LV) thickening in the absence of another cardiac or systemic disease. The condition is associated with sudden and unexpected death in young individuals including trained athletes. HCM represents a genetic disorder caused by mutations in genes encoding sarcomeric proteins of the cardiac myocyte. This review article discusses the genetics behind HCM, its clinical presentation, and diagnosis and the present-day pharmacological management of HCM...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29184265/long-term-low-intensity-endurance-exercise-along-with-blood-flow-restriction-improves-muscle-mass-and-neuromuscular-junction-compartments-in-old-rats
#15
Mohammad-Ali Bahreini Pour, Siyavash Joukar, Fariborz Hovanloo, Hamid Najafipour
Background: During the aging process, muscle atrophy and neuromuscular junction remodeling are inevitable. The present study aimed to clarify whether low-intensity aerobic exercise along with limb blood-flow restriction (BFR) could improve aging-induced muscle atrophy and nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. Methods: Forty-eight male Wistar rats, aged 23-24 months, were randomly divided into control, sham (Sh: subjected to surgery without BFR), BFR (subjected to BFR), exercise (Ex: subjected to 10 weeks of low-intensity exercise), Sh+Ex, and BFR+Ex groups...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29150779/perioperative-transesophageal-echocardiography-for-non-cardiac-surgery
#16
REVIEW
Ashraf Fayad, Sasha K Shillcutt
PURPOSE: The use of transesophageal echocardiography (TEE) has evolved to include patients undergoing high-risk non-cardiac procedures and patients with significant cardiac disease undergoing non-cardiac surgery. Implementation of basic TEE education in training programs has increased across a broad spectrum of procedures in the perioperative arena. This paper describes the use of perioperative TEE in non-cardiac surgery and provides an overview of the basic TEE examination. PRINCIPAL FINDINGS: Perioperative TEE is used to monitor hemodynamic parameters in non-cardiac procedures where there is a high risk of hemodynamic instability...
April 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29127601/interpreting-adaptation-to-concurrent-compared-with-single-mode-exercise-training-some-methodological-considerations
#17
REVIEW
Jackson J Fyfe, Jeremy P Loenneke
Incorporating both endurance and resistance training into an exercise regime is termed concurrent training. While there is evidence that concurrent training can attenuate resistance training-induced improvements in maximal strength and muscle hypertrophy, research findings are often equivocal, with some suggesting short-term concurrent training may instead further enhance muscle hypertrophy versus resistance training alone. These observations have questioned the validity of the purported 'interference effect' on muscle hypertrophy with concurrent versus single-mode resistance training...
February 2018: Sports Medicine
https://www.readbyqxmd.com/read/29123487/hypertrophy-stimulation-at-the-onset-of-type-i-diabetes-maintains-the-soleus-but-not-the-edl-muscle-mass-in-wistar-rats
#18
Marco A S Fortes, Maria V M Scervino, Gabriel N Marzuca-Nassr, Kaio F Vitzel, Carlos H da Justa Pinheiro, Rui Curi
Diabetes mellitus induces a reduction in skeletal muscle mass and strength. Strength training is prescribed as part of treatment since it improves glycemic control and promotes increase of skeletal muscle mass. The mechanisms involved in overload-induced muscle hypertrophy elicited at the establishment of the type I diabetic state was investigated in Wistar rats. The purpose was to examine whether the overload-induced hypertrophy can counteract the hypotrophy associated to the diabetic state. The experiments were performed in oxidative (soleus) or glycolytic (EDL) muscles...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29053943/inflammation-status-of-healthy-young-men-initial-and-specific-responses-to-resistance-training
#19
Johanna K Ihalainen, Heikki Peltonen, Göran Paulsen, Juha P Ahtiainen, Ritva S Taipale, Mari Hämäläinen, Eeva Moilanen, Antti A Mero
Our primary aim was to study the effects of a 4-week preparatory resistance-training (RT) period followed by 12 weeks of 2 specific RT protocols (either hypertrophic-strength (HS) or strength-hypertrophy-power training) on inflammation markers and the possible relationship of the changes in abdominal fat and lean mass to the changes in inflammation status. A total of 82 healthy men were included in the study. Maximal concentric leg press strength (1-repetition maximum), total body lean mass, total body and abdominal fat mass, circulating high-sensitivity C-reactive protein, interleukin-6, interleukin-1 receptor antagonist (IL-1ra), monocyte chemoattractant protein 1 (MCP-1), and selected adipocytokines (resistin, adiponectin, and leptin) concentrations were measured before and after 4 (wk4) and 16 weeks (wk16) of RT...
March 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29043659/magnitude-of-muscle-strength-and-mass-adaptations-between-high-load-resistance-training-versus-low-load-resistance-training-associated-with-blood-flow-restriction-a-systematic-review-and-meta-analysis
#20
REVIEW
Manoel E Lixandrão, Carlos Ugrinowitsch, Ricardo Berton, Felipe C Vechin, Miguel S Conceição, Felipe Damas, Cleiton A Libardi, Hamilton Roschel
BACKGROUND: Low-load resistance training (< 50% of one-repetition maximum [1RM]) associated with blood-flow restriction (BFR-RT) has been thought to promote increases in muscle strength and mass. However, it remains unclear if the magnitude of these adaptations is similar to conventional high-load resistance training (> 65% 1RM; HL-RT). OBJECTIVE: To compare the effects of HL- versus BFR-RT on muscle adaptations using a systematic review and meta-analysis procedure...
February 2018: Sports Medicine
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