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https://www.readbyqxmd.com/read/28534155/myocardial-delayed-enhancement-ct-initial-experience-in-children-and-young-adults
#1
Hyun Woo Goo
BACKGROUND: Clinical utility of myocardial delayed enhancement CT has not been reported in children and young adults. OBJECTIVE: To describe initial experience of myocardial delayed enhancement CT regarding image quality, radiation dose and identification of myocardial lesions in children and young adults. MATERIALS AND METHODS: Between August 2013 and November 2016, 29 consecutive children and young adults (median age 16 months) with suspected coronary artery or myocardial abnormality underwent arterial- and delayed-phase cardiac CT at our institution...
May 23, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28528235/mapping-natural-radioactivity-of-soil-samples-in-different-regions-of-punjab-india
#2
Komal Saini, B S Bajwa
Thallium activated sodium iodide (NaI(Tl)) detector and multi channel analyzer has been utilized to measure gamma rays emitted by radio nuclides found in soil samples of south-west (SW) region of Punjab state, India where elevated level of uranium of around value of 700µg/l in groundwater has been reported. For comparative study, soil samples were also collected and analyzed from west (W) and north east (NE) regions of the state. Uranium and potassium has been found to be comparatively higher in SW region whereas thorium level is higher in W and NE part of Punjab state...
May 13, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28514699/profiling-of-illicit-cocaine-seized-in-china-by-icp-ms-analysis-of-inorganic-elements
#3
Cuimei Liu, Zhendong Hua, Xin Meng
For the first time in China, the inorganic element profiling of cocaine specimens was performed at the National Narcotics Laboratory. An inductive coupled plasma-mass spectrometry (ICP-MS) method was developed and validated for simultaneous analysis of 26 inorganic elements, including sodium (Na), magnesium (Mg), aluminuim (Al), potassium (K), calcium (Ca), vanadium (V), chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium (Se), molybdenum (Mo), silver (Ag), cadmium (Cd), antimony (Sb), barium (Ba), lanthanum (La), cerium (Ce), thallium (Tl), lead (Pb), thorium (Th), and uranium (U) in illicit cocaine samples...
April 29, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28507823/cells-tile-a-flat-plane-by-controlling-geometries-during-morphogenesis-of-pyropia-thalli
#4
Kai Xu, Yan Xu, Dehua Ji, Ting Chen, Changsheng Chen, Chaotian Xie
BACKGROUND: Pyropia haitanensis thalli, which are made of a single layer of polygonal cells, are a perfect model for studying the morphogenesis of multi-celled organisms because their cell proliferation process is an excellent example of the manner in which cells control their geometry to create a two-dimensional plane. METHODS: Cellular geometries of thalli at different stages of growth revealed by light microscope analysis. RESULTS: This study showed the cell division transect the middle of the selected paired-sides to divide the cell into two equal portions, thus resulting in cell sides ≥4 and keeping the average number of cell sides at approximately six even as the thallus continued to grow, such that more than 90% of the cells in thalli longer than 0...
2017: PeerJ
https://www.readbyqxmd.com/read/28504092/mycoplasma-sp-infection-in-captive-marcgrave-s-capuchin-monkeys-sapajus-flavius
#5
Ayodhya C Ramalho, Ricardo R Guerra, Anna C B Mongruel, Odilon Vidotto, Ricardo B Lucena, Monalisa V S F Guerra, Thállitha S W J Vieira, Rafael F C Vieira
Three species of hemoplasmas are known to infect monkeys, 'Candidatus Mycoplasma kahanei', 'Candidatus Mycoplasma haemomacaque' and 'Candidatus Mycoplasma aoti'. Marcgrave's capuchin monkey (Sapajus flavius) is a critically endangered neotropical primate species of the Brazilian Atlantic Forest, and thus, sustained efforts are needed to protect the health and well-being of these animals. This study has aimed to screen 12 captive S. flavius from the State of Paraíba, northeastern Brazil, for hemoplasma infection...
April 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28494211/pecoramyces-ruminantium-gen-nov-sp-nov-an-anaerobic-gut-fungus-from-the-feces-of-cattle-and-sheep
#6
Radwa A Hanafy, Mostafa S Elshahed, Audra S Liggenstoffer, Gareth W Griffith, Noha H Youssef
The anaerobic gut fungi (AGF) inhabit the rumen and alimentary tracts of multiple ruminant and nonruminant herbivores, belong to a distinct phylum-level lineage (Neocallimastigomycota), and play an important role in plant biomass degradation in many herbivores. As part of a wider effort to obtain AGF with high lignocellulolytic capacities, we isolated and characterized four different AGF strains from the feces of cattle and sheep. Microscopically, isolates produced monocentric thalli and monoflagellated zoospores...
April 18, 2017: Mycologia
https://www.readbyqxmd.com/read/28482695/previously-undescribed-antioxidative-azocinyl-morpholinone-alkaloid-from-red-seaweed-gracilaria-opuntia-with-anti-cyclooxygenase-and-lipoxygenase-properties
#7
Fasina Makkar, Kajal Chakraborty
In vitro antioxidative and anti-inflammatory bioassay-guided fractionation of the methanol: ethyl acetate crude extract of the thalli of red seaweed Gracilaria opuntia collected from the Gulf of Mannar led to the isolation of a new morpholine alkaloid 3-(2-ethyl-6-((3Z,7Z)-1,2,5,6-tetrahydroazocin-5-yl)hexyl) morpholin-6-one. The substituted azocinyl morpholinone recorded significant 1,1-diphenyl-2-picryl-hydrazil free radical scavenging activities (IC50 ~ 0.086 mg/mL) compared to the commercially available antioxidants, butylated hydroxyanisole, butylated hydroxytoluene, and α-tocopherol (IC50 > 0...
May 8, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28482319/is-there-a-risk-of-trace-element-contamination-in-herbal-preparations-a-test-study-on-the-lichen-cetraria-islandica
#8
Paolo Giordani, Vincenzo Minganti, Daniele Brignole, Paola Malaspina, Laura Cornara, Giuliana Drava
Lichens are a source of unique secondary metabolites, which have been proved to have many biological properties with possible pharmaceutical roles, including e.g. antioxidant, antimicrobial, antifungal or anti-inflammatory activities and to be worth of consideration for potential human use. However, lichens lack cuticolar tissues and are exposed to several atmospheric contaminants, including trace elements. This work aims at exploring the potential toxicity of herbal preparations derived by the lichen Cetraria islandica due to trace element contamination, testing whether different concentrations may be observed, depending on the origin of the raw material...
April 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/28473823/recombinant-human-ifn%C3%AE-2b-response-promotes-vaginal-epithelial-cells-defense-against-candida-albicans
#9
Ting Li, Xiaoxi Niu, Xu Zhang, Suxia Wang, Zhaohui Liu
Classical antifungal drugs have been subjected to restrictions due to drug toxicity, drug resistance, bioavailability, and detrimental drug interactions. Type I interferon (IFN) exerts direct distinct immunostimulatory or immunomodulatory actions; however, little is known regarding the anti-fungal reactions of vaginal epithelial cells (VECs) induced by the type I IFN response. Therefore, in the present study, we evaluated the cytotoxic activity, immunocompetent cytokine responses, and non-B IgG production of the VK2/E6E7 VEC line following recombinant human IFN α-2b (rhIFNα-2b) treatment in response to Candida albicans...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28470630/characteristics-of-single-and-dual-photopeak-energy-window-acquisitions-with-thallium-201-iq-spect-ct-system
#10
Takayuki Shibutani, Masahisa Onoguchi, Hiroto Yoneyama, Takahiro Konishi, Shinro Matsuo, Kenichi Nakajima, Seigo Kinuya
OBJECTIVES: Although dual-energy (DE) acquisition with conventional (201)Tl myocardial perfusion SPECT has several advantages such as improved attenuation of the inferior wall and increased acquisition counts, the characteristics of IQ-SPECT have not been fully evaluated. We evaluate the difference of characteristics between single-energy (SE) and dual-energy (DE) imaging using (201)Tl myocardial IQ-SPECT. METHODS: Two myocardial phantoms were created simulating normal myocardium and infarction of the inferior wall...
May 3, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28469335/pediatric-osteosarcoma-an-updated-review
#11
REVIEW
Shachi Jain Taran, Rakesh Taran, Nagraj B Malipatil
Osteosarcoma (OS), the most common type of primary malignant bone tumor, is defined by the presence of malignant mesenchymal cells producing osteoid or immature bone. The peak incidence of the most frequent type of OS, i.e., high-grade central OS, occurs in the second decade of life during the adolescent growth spurt. Most patients suffer from the pain and swelling in the involved region and, usually, seek medical attention. Diagnosis is carried out by conventional radiographs, computed tomography, and magnetic resonance image (MRI)...
January 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28466867/enzyme-discovery-beyond-homology-a-unique-hydroxynitrile-lyase-in-the-bet-v1-superfamily
#12
Elisa Lanfranchi, Tea Pavkov-Keller, Eva-Maria Koehler, Matthias Diepold, Kerstin Steiner, Barbara Darnhofer, Jürgen Hartler, Tom Van Den Bergh, Henk-Jan Joosten, Mandana Gruber-Khadjawi, Gerhard G Thallinger, Ruth Birner-Gruenberger, Karl Gruber, Margit Winkler, Anton Glieder
Homology and similarity based approaches are most widely used for the identification of new enzymes for biocatalysis. However, they are not suitable to find truly novel scaffolds with a desired function and this averts options and diversity. Hydroxynitrile lyases (HNLs) are an example of non-homologous isofunctional enzymes for the synthesis of chiral cyanohydrins. Due to their convergent evolution, finding new representatives is challenging. Here we show the discovery of unique HNL enzymes from the fern Davallia tyermannii by coalescence of transcriptomics, proteomics and enzymatic screening...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28466571/synthesis-of-relaxin-2-and-insulin-like-peptide-5-enabled-by-novel-tethering-and-traceless-chemical-excision
#13
Kishore Thalluri, Binbin Kou, Xu Yang, Alexander N Zaykov, John P Mayer, Vasily M Gelfanov, Fa Liu, Richard D DiMarchi
This report presents an entirely chemical, general strategy for the synthesis of relaxin-2 and insulin-like peptide 5. Historically, these two peptides have represented two of the more synthetically challenging members of the insulin superfamily. The key synthetic steps involve two sequential oxime ligations to covalently link the individual A-chain and B-chain, followed by disulfide bond formation under aqueous, redox conditions. This is followed by two chemical reactions that employ diketopiperazine cyclization-mediated cleavage and ester hydrolysis to liberate the connecting peptide and the heterodimeric product...
May 3, 2017: Journal of Peptide Science: An Official Publication of the European Peptide Society
https://www.readbyqxmd.com/read/28464090/genetic-variance-and-covariance-and-breed-differences-for-feed-intake-and-average-daily-gain-to-improve-feed-efficiency-in-growing-cattle
#14
K J Retallick, J M Bormann, R L Weaber, M D MacNeil, H L Bradford, H C Freetly, K E Hales, D W Moser, W M Snelling, R M Thallman, L A Kuehn
Feed costs are a major economic expense in finishing and developing cattle; however, collection of feed intake data is costly. Examining relationships among measures of growth and intake, including breed differences, could facilitate selection for efficient cattle. Objectives of this study were to estimate genetic parameters for growth and intake traits and compare indices for feed efficiency to accelerate selection response. On-test ADFI and on-test ADG (TESTADG) and postweaning ADG (PWADG) records for 5,606 finishing steers and growing heifers were collected at the U...
April 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28458220/chemistry-and-phase-evolution-during-roasting-of-toxic-thallium-bearing-pyrite
#15
Paula Lopez-Arce, Javier Garcia-Guinea, Fernando Garrido
In the frame of a research project on microscopic distribution and speciation of geogenic thallium (Tl) from contaminated mine soils, Tl-bearing pyrite ore samples from Riotinto mining district (Huelva, SW Spain) were experimentally fired to simulate a roasting process. Concentration and volatility behavior of Tl and other toxic heavy metals was determined by quantitative ICP-MS, whereas semi-quantitative mineral phase transitions were identified by in situ thermo X-Ray Diffraction (HT-XRD) and Scanning Electron Microscopy with Energy Dispersive Spectroscopy (SEM-EDS) analyses after each firing temperature...
April 24, 2017: Chemosphere
https://www.readbyqxmd.com/read/28455153/multi-institutional-analysis-of-radiation-modality-use-and-postoperative-outcomes-of-neoadjuvant-chemoradiation-for-esophageal-cancer
#16
Steven H Lin, Kenneth W Merrell, Jincheng Shen, Vivek Verma, Arlene M Correa, Lu Wang, Peter F Thall, Neha Bhooshan, Sarah E James, Michael G Haddock, Mohan Suntharalingam, Minesh P Mehta, Zhongxing Liao, James D Cox, Ritsuko Komaki, Reza J Mehran, Michael D Chuong, Christopher L Hallemeier
PURPOSE: Relative radiation dose exposure to vital organs in the thorax could influence clinical outcomes in esophageal cancer (EC). We assessed whether the type of radiation therapy (RT) modality used was associated with postoperative outcomes after neoadjuvant chemoradiation (nCRT). PATIENTS AND METHODS: Contemporary data from 580 EC patients treated with nCRT at 3 academic institutions from 2007 to 2013 were reviewed. 3D conformal RT (3D), intensity modulated RT (IMRT) and proton beam therapy (PBT) were used for 214 (37%), 255 (44%), and 111 (19%) patients, respectively...
April 25, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28451361/vapor-solid-synthesis-of-monolithic-single-crystalline-cop-nanowire-electrodes-for-efficient-and-robust-water-electrolysis
#17
Wei Li, Xuefei Gao, Dehua Xiong, Fang Xia, Jian Liu, Wei-Guo Song, Junyuan Xu, Sitaramanjaneya Mouli Thalluri, M F Cerqueira, Xiuli Fu, Lifeng Liu
Electrochemical water splitting into hydrogen and oxygen is a promising technology for sustainable energy storage. The development of earth-abundant transition metal phosphides (TMPs) to catalyze the hydrogen evolution reaction (HER) and TMP-derived oxy-hydroxides to catalyze the oxygen evolution reaction (OER) has recently drawn considerable attention. However, most monolithically integrated metal phosphide electrodes are prepared by laborious multi-step methods and their operational stability at high current densities has been rarely studied...
April 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28451342/effect-of-ring-rotation-upon-gas-adsorption-in-sifsix-3-m-m-fe-ni-pillared-square-grid-networks
#18
Sameh K Elsaidi, Mona H Mohamed, Cory M Simon, Efrem Braun, Tony Pham, Katherine A Forrest, Wenqian Xu, Debasis Banerjee, Brian Space, Michael J Zaworotko, Praveen K Thallapally
Dynamic and flexible metal-organic frameworks (MOFs) that respond to external stimuli, such as stress, light, heat, and the presence of guest molecules, hold promise for applications in chemical sensing, drug delivery, gas separations, and catalysis. A greater understanding of the relationship between flexible constituents in MOFs and gas adsorption may enable the rational design of MOFs with dynamic moieties and stimuli-responsive behavior. Here, we detail the effect of subtle structural changes upon the gas sorption behavior of two "SIFSIX" pillared square grid frameworks, namely SIFSIX-3-M (M = Ni, Fe)...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28446200/human-germ-stem-cell-specific-gene-tex19-influences-cancer-cell-proliferation-and-cancer-prognosis
#19
Vicente Planells-Palop, Ali Hazazi, Julia Feichtinger, Jana Jezkova, Gerhard Thallinger, Naif O Alsiwiehri, Mikhlid Almutairi, Lee Parry, Jane A Wakeman, Ramsay J McFarlane
BACKGROUND: Cancer/testis (CT) genes have expression normally restricted to the testis, but become activated during oncogenesis, so they have excellent potential as cancer-specific biomarkers. Evidence is starting to emerge to indicate that they also provide function(s) in the oncogenic programme. Human TEX19 is a recently identified CT gene, but a functional role for TEX19 in cancer has not yet been defined. METHODS: siRNA was used to deplete TEX19 levels in various cancer cell lines...
April 26, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28444610/publicly-available-datasets-on-thallium-tl-in-the-environment-a-comment-on-presence-of-thallium-in-the-environment-sources-of-contaminations-distribution-and-monitoring-methods-by-bozena-karbowska-environ-monit-assess-2016-188-640-doi-10-1007-s10661-016-5647
#20
Patrice de Caritat, Clemens Reimann
This comment highlights a whole series of datasets on thallium concentrations in the environment that were overlooked in the recent review by Karbowska, Environmental Monitoring and Assessment, 188, 640, 2016 in this journal. Geochemical surveys carried out over the last few decades all over the world at various scales and using different sampling media have reported the concentration of thallium (and dozens more elements) in tens of thousands of samples. These datasets provide a 'real-world' foundation upon which source apportionment investigations can be based, monitoring programs devised and modelling studies designed...
May 2017: Environmental Monitoring and Assessment
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