keyword
MENU ▼
Read by QxMD icon Read
search

brushite

keyword
https://www.readbyqxmd.com/read/28962775/new-in-situ-synthetized-hydrogel-composite-based-on-alginate-and-brushite-as-a-potential-ph-sensitive-drug-delivery-system
#1
Seyed Mohammad Hossein Dabiri, Alberto Lagazzo, Fabrizio Barberis, Amirreza Shayganpour, Elisabetta Finocchio, Laura Pastorino
A Series of in-situ alginate-brushite (Alg-Bru) hydrogel composites were fabricated to optimize release profile of ibuprofen (Ibu) and to avoid burst releases associated with the pure form of the hydrogels. The Bru crystals were synthetized and dispersed during the crosslinking process of Alg matrix. The beads with different formulations were subject to various characterization tests such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), dynamic mechanical analysis (DMA), and swelling...
December 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28948757/in-situ-synchrotron-x-ray-diffraction-analysis-of-the-setting-process-of-brushite-cement-reaction-and-crystal-growth
#2
Jun Luo, Francisco Javier Martinez-Casado, Olivier Balmes, Jiaojiao Yang, Cecilia Persson, Håkan Engqvist, Wei Xia
Brushite cements are fast self-setting materials that can be used as bone substitute materials. Although tracing their fast setting process is a challenge, it is important for the understanding of the same, which in turn is important for the material's further development and use in the clinics. In this study, the setting rate, phase formation, and crystal growth of brushite cements were quantitatively studied by in situ synchrotron powder X-ray diffraction (SXRD) on a time scale of seconds. The influence of reactant ratios and a retardant (citric acid) on the setting reaction were analyzed...
October 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28945133/dual-energy-computed-tomography-of-canine-uroliths
#3
Stephanie G Nykamp
OBJECTIVE To determine whether dual-energy CT (DECT) could accurately differentiate the composition of common canine uroliths in a phantom model. SAMPLE 30 canine uroliths with pure compositions. PROCEDURES Each urolith was composed of ≥ 70% struvite (n = 10), urate (8), cystine (5), calcium oxalate (4), or brushite (3) as determined by standard laboratory methods performed at the Canadian Veterinary Urolith Centre. Uroliths were suspended in an agar phantom, and DECT was performed at low (80 kV) and high (140 kV) energies...
October 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28918134/crystallization-and-demineralization-phenomena-in-washed-rind-cheese
#4
Gil F Tansman, Paul S Kindstedt, John M Hughes
This report documents an observational study of a high-moisture washed-rind cheese. Three batches of cheese were sampled on a weekly basis for 6 wk and again at wk 10. Center, under-rind, rind, and smear samples were tested for pH, moisture, and selected mineral elements. Powder x-ray diffractometry and petrographic microscopy were applied to identify and image the crystal phases. The pH of the rind increased by over 2 pH units by wk 10. The pH of the under-rind increased but remained below the rind pH, whereas the center pH decreased for most of aging and only began to rise after wk 5...
November 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28916883/different-post-processing-conditions-for-3d-bioprinted-%C3%AE-tricalcium-phosphate-scaffolds
#5
Liciane Sabadin Bertol, Rodrigo Schabbach, Luis Alberto Loureiro Dos Santos
The development of 3D printing hardware, software and materials has enabled the production of bone substitute scaffolds for tissue engineering. Calcium phosphates cements, such as those based on α-tricalcium phosphate (α-TCP), have recognized properties of osteoinductivity, osteoconductivity and resorbability and can be used to 3D print scaffolds to support and induce tissue formation and be replaced by natural bone. At present, however, the mechanical properties found for 3D printed bone scaffolds are only satisfactory for non-load bearing applications...
September 15, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28882031/a-multiregional-italian-cohort-of-24-hour-urine-metabolic-evaluation-in-renal-stone-formers
#6
Francesco Esperto, Martino Marangella, Alberto Trinchieri, Michele Petrarulo, Roberto Miano
BACKGROUND: Nephrolithiasis is a common condition with several studies documenting an increased prevalence over the past four decades. EAU and AUA guidelines recommend 24-hour urine metabolic evaluation in high-risk stone formers. Aim of this study is to retrospectively evaluate the first three years of experience with Lithotest® (Biohealth Italia Srl, Turin, Italy) through the analysis of demographic, clinical and biochemical data collected from a large cohort of patients with kidney stones...
September 7, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28866230/strontium-doped-injectable-bone-cement-for-potential-drug-delivery-applications
#7
Ali Taha, Muhammad Akram, Zaidoon Jawad, Ammar Z Alshemary, Rafaqat Hussain
Microwave assisted wet precipitation method was used to synthesize calcium deficient strontium doped β-tricalcium phosphate (Sr-βTCP) with a chemical formula of Ca2.96-xSrx(PO4)2. Sr-βTCP was reacted with monocalcium phosphate monohydrate [Ca(H2PO4)2.H2O, MCPM] in presence of water to furnish corresponding Sr containing brushite cement (Sr-Brc). The samples were characterized by using X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28841980/electrochemical-enzyme-biosensors-based-on-calcium-phosphate-materials-for-tyramine-detection-in-food-samples
#8
Marta Sánchez-Paniagua López, Esther Redondo-Gómez, Beatriz López-Ruiz
Electrochemical tyrosinase biosensors for tyramine determination were developed by the immobilization of the enzyme in calcium phosphate materials (CaPs) followed by cross-linking with glutaraldehyde. Tyramine was detected by the electrochemical reduction at -0.1V of the o- enzymatically-formed dopaquinone. Three different CaPs were explored as immobilization systems, monetite, brushite and brushite cement. Biosensors based on brushite matrices provide better analytical properties than the monetite one. Compared to brushite, a 10-fold increase of sensitivity was obtained with the brushite cement-based biosensor, which highlights the effect of brushite crystal formation in the presence of the enzyme in the biosensor performance...
December 1, 2017: Talanta
https://www.readbyqxmd.com/read/28822796/papillary-ductal-plugging-is-a-mechanism-for-early-stone-retention-in-brushite-stone-disease
#9
James C Williams, Michael S Borofsky, Sharon B Bledsoe, Andrew P Evan, Fredric L Coe, Elaine M Worcester, James E Lingeman
PURPOSE: Mechanisms of early stone retention in the kidney are under studied and poorly understood. To date attachment via Randall plaque is the only widely accepted theory in this regard, which is best described in idiopathic calcium oxalate stone formers. Brushite stone formers are known to have distinct papillary morphology relative to calcium oxalate stone formers. As such we sought to determine whether stone attachment mechanisms in such patients may be similarly unique. MATERIALS AND METHODS: Patients undergoing percutaneous and or ureteroscopic procedures for stone removal consented to endoscopic renal papillary examination and individual stone collection...
August 16, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28808430/amelogenin-affects-brushite-crystal-morphology-and-promotes-its-phase-transformation-to-monetite
#10
Dongni Ren, Qichao Ruan, Jinhui Tao, Jonathan Lo, Steven Nutt, Janet Moradian-Oldak
Amelogenin protein is involved in organized apatite crystallization during enamel formation. Brushite (CaHPO4·2H2O), one of the precursors of hydroxyapatite mineralization in vitro, has been used for fabrication of biomaterials for hard tissue repair. In order to explore its potential application in biomimetic material synthesis, we studied the influence of the enamel protein amelogenin on brushite morphology and phase transformation to monetite. Our results show that amelogenin can adsorb onto the surface of brushite, leading to the formation of layered morphology on the (010) face...
September 7, 2016: Crystal Growth & Design
https://www.readbyqxmd.com/read/28794471/quantifying-the-efficiency-of-hydroxyapatite-mineralising-peptides
#11
Robyn Plowright, David J Belton, David L Kaplan, Carole C Perry
We present a non-destructive analytical calibration tool to allow quantitative assessment of individual calcium phosphates such as hydroxyapatite (HAP) from mixtures including brushite. Many experimental approaches are used to evaluate the mineralising capabilities of biomolecules including peptides. However, it is difficult to quantitatively compare the efficacy of peptides in the promotion of mineralisation when inseparable mixtures of different minerals are produced. To address this challenge, a series of hydroxyapatite and brushite mixtures were produced as a percent/weight (0-100%) from pure components and multiple (N = 10) XRD patterns were collected for each mixture...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28763481/osteoclastic-differentiation-and-resorption-is-modulated-by-bioactive-metal-ions-co2-cu2-and-cr3-incorporated-into-calcium-phosphate-bone-cements
#12
Anne Bernhardt, Martha Schamel, Uwe Gbureck, Michael Gelinsky
Biologically active metal ions in low doses have the potential to accelerate bone defect healing. For successful remodelling the interaction of bone graft materials with both bone-forming osteoblasts and bone resorbing osteoclasts is crucial. In the present study brushite forming calcium phosphate cements (CPC) were doped with Co2+, Cu2+ and Cr3+ and the influence of these materials on osteoclast differentiation and activity was examined. Human osteoclasts were differentiated from human peripheral blood mononuclear cells (PBMC) both on the surface and in indirect contact to the materials on dentin discs...
2017: PloS One
https://www.readbyqxmd.com/read/28735216/elastic-properties-and-strain-to-crack-initiation-of-calcium-phosphate-bone-cements-revelations-of-a-high-resolution-measurement-technique
#13
Ingrid Ajaxon, Alice Acciaioli, Giacomo Lionello, Maria-Pau Ginebra, Caroline Öhman-Mägi, Massimiliano Baleani, Cecilia Persson
Calcium phosphate cements (CPCs) should ideally have mechanical properties similar to those of the bone tissue the material is used to replace or repair. Usually, the compressive strength of the CPCs is reported and, more rarely, the elastic modulus. Conversely, scarce or no data are available on Poisson's ratio and strain-to-crack-initiation. This is unfortunate, as data on the elastic response is key to, e.g., numerical model accuracy. In this study, the compressive behaviour of brushite, monetite and apatite cements was fully characterised...
October 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28664170/data-on-tof-sims-analysis-of-cu-2-co-2-and-cr-3-doped-calcium-phosphate-cements
#14
Anja Henß, Martha Schamel, Uwe Gbureck, Michael Gelinsky, Anja Lode
This article contains data of time of flight secondary ion mass spectrometry (TOF-SIMS) analysis of brushite-forming calcium phosphate cements doped with biologically active metal ions. This data are related to the research article "Cu(2+), Co(2+) and Cr(3+) doping of a calcium phosphate cement influences materials properties and response of human mesenchymal stromal cells" (Schamel et al., 2017) [1]. Cu(2+), Co(2+) and Cr(3+) doped β-tricalcium phosphate precursor powders were used to prepare cement samples...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28642715/elastin-like-protein-with-statherin-derived-peptide-controls-fluorapatite-formation-and-morphology
#15
Kseniya Shuturminska, Nadezda V Tarakina, Helena S Azevedo, Andrew J Bushby, Alvaro Mata, Paul Anderson, Maisoon Al-Jawad
The process of enamel biomineralization is multi-step, complex and mediated by organic molecules. The lack of cells in mature enamel leaves it unable to regenerate and hence novel ways of growing enamel-like structures are currently being investigated. Recently, elastin-like protein (ELP) with the analog N-terminal sequence of statherin (STNA15-ELP) has been used to regenerate mineralized tissue. Here, the STNA15-ELP has been mineralized in constrained and unconstrained conditions in a fluoridated solution...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28642196/gdf5-significantly-augments-the-bone-formation-induced-by-an-injectable-plga-fiber-reinforced-brushite-forming-cement-in-a-sheep-defect-model-of-lumbar-osteopenia
#16
Matthias Bungartz, Elke Kunisch, Stefan Maenz, Victoria Horbert, Long Xin, Francesca Gunnella, Joerg Mika, Juliane Borowski, Sabine Bischoff, Harald Schubert, Andre Sachse, Bernhard Illerhaus, Jens Günster, Jörg Bossert, Klaus D Jandt, Frank Plöger, Raimund W Kinne, Olaf Brinkmann
BACKGROUND CONTEXT: Biodegradable calcium phosphate cement (CPC) represents a promising option for the surgical treatment of osteoporotic vertebral fractures. Due to augmented local bone catabolism, however, additional targeted delivery of bone morphogenetic proteins with the CPC may be needed to promote rapid and complete bone regeneration. PURPOSE: In the present study, an injectable, poly (l-lactide-co-glycolide) acid (PLGA)-fiber reinforced, brushite-forming cement (CPC) containing the bone morphogenetic protein GDF5 was tested in a sheep lumbar osteopenia model...
June 19, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28629018/the-bone-building-blues-self-hardening-copper-doped-calcium-phosphate-cement-and-its-in-vitro-assessment-against-mammalian-cells-and-bacteria
#17
Julietta V Rau, Victoria M Wu, Valerio Graziani, Inna V Fadeeva, Alexander S Fomin, Marco Fosca, Vuk Uskoković
A blue calcium phosphate cement with optimal self-hardening properties was synthesized by doping whitlockite (β-TCP) with copper ions. The mechanism and the kinetics of the cement solidification process were studied using energy dispersive X-ray diffraction and it was found out that hardening was accompanied by the phase transition from TCP to brushite. Reduced lattice parameters in all crystallographic directions resulting from the rather low (1:180) substitution rate of copper for calcium was consistent with the higher ionic radius of the latter...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28619686/low-dose-bmp-2-is-sufficient-to-enhance-the-bone-formation-induced-by-an-injectable-plga-fiber-reinforced-brushite-forming-cement-in-a-sheep-defect-model-of-lumbar-osteopenia
#18
Francesca Gunnella, Elke Kunisch, Matthias Bungartz, Stefan Maenz, Victoria Horbert, Long Xin, Joerg Mika, Juliane Borowski, Sabine Bischoff, Harald Schubert, Peter Hortschansky, Andre Sachse, Bernhard Illerhaus, Jens Günster, Jörg Bossert, Klaus D Jandt, Frank Plöger, Raimund W Kinne, Olaf Brinkmann
BACKGROUND CONTEXT: Bioresorbable calcium phosphate cement (CPC) may be suitable for vertebroplasty/kyphoplasty of osteoporotic vertebral fractures. However, additional targeted delivery of osteoinductive bone morphogenetic proteins (BMPs) in the CPC may be required to counteract the augmented local bone catabolism and support complete bone regeneration. PURPOSE: The study aimed at testing an injectable, poly (l-lactide-co-glycolide) acid (PLGA)-fiber reinforced, brushite-forming cement (CPC) containing low-dose bone morphogenetic protein BMP-2 in a sheep lumbar osteopenia model...
June 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28616254/in-vitro-ion-adsorption-and-cytocompatibility-of-dicalcium-phosphate-ceramics
#19
Martha Schamel, Jake E Barralet, Jürgen Groll, Uwe Gbureck
BACKGROUND: In vitro cell testing of degradable bioceramics such as brushite or monetite is often challenging due to the ion release into or adsorption from the culture medium. These ionic changes are then mostly responsible for cell proliferation and activity, which prohibits the investigation of effects originating from surface topography or further material modifications. METHODS: Here, we aimed to solve this problem by developing a pre-conditioning regime following the repeated immersion of brushite and monetite samples in various Ca(2+), Mg(2+) and PO4(3-) containing electrolytes, followed by studying ion adsorption / release as well as changes in phase composition and in vitro cytocompatibility with MG63 cells...
2017: Biomaterials Research
https://www.readbyqxmd.com/read/28590728/switchable-chiral-selection-of-aspartic-acids-by-dynamic-states-of-brushite
#20
Wenge Jiang, Haihua Pan, Zhisen Zhang, S Roger Qiu, J Dongun Kim, Xurong Xu, Ruikang Tang
We herein show the chiral recognition and separation of aspartic acid (Asp) enantiomers by achiral brushite due to the asymmetries of their dynamical steps in its nonequilibrium states. Growing brushite has a higher adsorption affinity to d-Asp, while l-Asp is predominant on the dissolving brushite surface. Microstructural characterization reveals that chiral selection is mainly attributed to brushite [101] steps, which exhibit two different configurations during crystal growth and dissolution, respectively, with each preferring a distinct enantiomer due to this asymmetry...
June 15, 2017: Journal of the American Chemical Society
keyword
keyword
111270
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"