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https://www.readbyqxmd.com/read/29599489/matrix-metalloproteinase-mediated-type-i-collagen-degradation-is-an-independent-predictor-of-increased-risk-of-acute-myocardial-infarction-in-postmenopausal-women
#1
Ditte Marie Bertelsen, Jesper Skov Neergaard, Cecilie Liv Bager, Signe Holm Nielsen, Niels Henry Secher, Jesper Hastrup Svendsen, Asger Reinstrup Bihlet, Jeppe Ragnar Andersen, Morten Asser Karsdal, Claus Christiansen, Henning Bay Nielsen
Acute myocardial infarction (AMI) is often underdiagnosed in women. It is therefore of interest to identify biomarkers that indicate increased risk of AMI and thereby help clinicians to have additional focus on the difficult AMI diagnosis. Type I Collagen, a component of the cardiac extracellular matrix, is cleaved by matrix metalloproteinases (MMPs) generating the neo-epitope C1M. We investigated the association between serum-C1M and AMI and evaluated whether C1M is a prognostic marker for outcome following AMI...
March 29, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29422732/an-interesting-presentation-of-pheochromocytoma
#2
Sunil Kumar Garg, Pragya Garg, Mehmet Urumdas
Pheochromocytoma is a rare cause of hypertension, but it could have severe consequences if not recognized and treated appropriately. Pheochromocytoma classically presents with paroxysms of hypertension and adrenergic symptoms including classic triad of episodic headache, sweating, and tachycardia. The clinical presentation of pheochromocytoma can mimic a number of other medical conditions including migraine, cardiac arrhythmias, myocardial infarction, and stroke, thus making the diagnosis of pheochromocytoma difficult, and treatment is directed toward presenting issue rather than underlying problem in such patients...
January 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28829745/everolimus-eluting-bioresorbable-scaffolds-in-patients-with-coronary-artery-disease-results-from-the-german-austrian-absorb-registry-gabi-r
#3
Holger M Nef, Jens Wiebe, Johannes Kastner, Julinda Mehilli, Thomas Muenzel, Christoph Naber, Till Neumann, Gert Richardt, Axel Schmermund, Jochen Woehrle, Ralf Zahn, Thomas Riemer, Stephan Achenbach, Christian W Hamm
AIMS: The aim of this study was to analyse the procedural results and midterm safety of everolimus-eluting bioresorbable vascular scaffolds (BVS) used for percutaneous coronary intervention in a large all-comers cohort from the German-Austrian ABSORB RegIstRy (GABI-R). METHODS AND RESULTS: A total of 3,231 patients were included in this prospective, observational, multicentre study (ClinicalTrials.gov NCT02066623) of consecutive patients undergoing BVS implantation between November 2013 and January 2016...
December 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28427124/-contemporary-use-of-ticagrelor-in-patients-with-acute-coronary-syndrome-after-discharge
#4
J Liu, H B Yan, L Song, Y H Hua, H J Zhao, C Liu, P Zhou, J N Li, Y Tan, Y M Yang, Y Wu
Objective: To investigate the degree and determinants of using ticagrelor among discharged patients with acute coronary syndrome (ACS). Methods: Patients with ACS in Fuwai hospital who were given ticagrelor after discharge between Jan. 2015 to Jun. 2015 were analyzed.The clinical characteristics and adherence to ticagrelor of these patients were collected by reviewing the electronic medical records and telephone interview.Date were statistically-analyzed. Results: Among all screened 404 patients, 158 (39.1%) patients prematurely stopped ticagrelor within 12 months, while 119(29...
April 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28019114/-lipids-and-cerebrovascular-disease-new-therapeutic-options-in-lowering-ldl-cholesterol
#5
Emese Lovadi, Péter Csécsei, Csenge Lovig, Zsófia Karádi, László Szapáry
Stroke is the third most common cause of death worldwide following myocardial infaction and malignancies, furthermore, its functional outcome is the worst of all conditions. Cholesterol, especially LDL-cholesterol plays a key role in the formation of atherosclerotic plaques. It has been verified recently that escalating incidence and mortality of cerebrovascular diseases are proportional to increased levels of LDL-cholesterol. Statin therapy undeniably reduces the risk of stroke, however other methods for decreasing lipid levels have not been proved significantly effective...
December 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27747059/latitude-timi-is-there-still-hope-for-anti-inflammatory-therapy-in-acute-myocardial-infaction
#6
COMMENT
Matthias Dewenter, Michael Wagner, Ali El-Armouche
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/26750696/left-ventricular-pseudoaneurysm-versus-aneurysm-a-diagnosis-dilemma
#7
Samarjit Bisoyi, Anjan K Dash, Debashish Nayak, Satyajit Sahoo, Raghunath Mohapatra
Free wall rupture of the left ventricle (LV) is a rare but life-threatening complication of acute myocardial infaction. Very rarely such rupture may be contained by the adhering pericardium creating a pseudoaneurysm. This condition warrants for an emergency surgery. Left ventricular aneurysm is the discrete thinning of the ventricular wall (<5 mm) with akinetic or dyskinetic wall motion causing an out-pouching of the ventricle. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is important...
January 2016: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/26165055/stent-dislodgement-in-the-distal-left-main-coronary-artery-and-its-successful-management-with-balloon-crushing-technique
#8
Zoran Stajić
INTRODUCTION: Stent entrapment and dislodgement in the coronary arteries is a rare but potentially fatal complication of percutaneous coronary intervention. Different retrival techniques of dislodged stents have previously been reported with high success rate but all of them are time-consuming, so as not quite useful in hemodinamically unstable patient. CASE REPORT: A 59-year old female patient with acute ST-elevation myocardial infaction of anterior wall was admitted for primary percutanous coronary intervention...
May 2015: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/25596013/effects-of-high-and-low-salt-intake-on-left-ventricular-remodeling-after-myocardial-infarction-in-normotensive-rats
#9
Ludimila Forechi, Marcelo Perim Baldo, Isabela Binotti de Araujo, Breno Valentim Nogueira, José Geraldo Mill
The dietary-sodium restriction is a standard approach following an acute myocardial infarction (MI). We examined the hypothesis in which the use of a high or low-sodium diet would worsen post-infarction left ventricular remodeling in rats and facilitate the development of heart failure. Left coronary artery ligation or sham-operated (SO) was produced in male Wistar rats (250-290 g). After surgery, animals were assigned to one of the three diets: standard amount of sodium (0.3% NaCl, SO and MI groups), a high-sodium diet (0...
February 2015: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/25214949/expressions-of-socs-1-and-socs-3-in-the-myocardium-of-patients-with-sudden-cardiac-death
#10
Liang Chen, Hao Tang, Yan-Bing Liang, Zhi-Bin Chen, Zhen-Yu Li, Zi-Tong Huang, Long-Yuan Jiang, Zhong-Fu Ma
BACKGROUND: As the regulators of cytokines, suppressors of cytokine signaling (SOCS) play an important role in the inflammation reaction. Some studies found that SOCS-1 and SOCS-3 were involved in the pathogenesis of some inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease. But the expressions of SOCS in coronary heart disease have not yet been reported. This study aimed to investigate the expression and clinical significance of SOCS-1 and SOCS-3 in the myocardium of patients with sudden cardiac death (SCD)...
2010: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/24175420/interventional-therapy-in-diabetic-foot-risk-factors-clinical-events-and-prognosis-at-one-year-follow-up-a-study-of-103-cases
#11
Marco Matteo Ciccone, Alfredo Marchese, Aikaterini Generali, Cataldo Loiodice, Francesca Cortese, Rosa Carbonara, Pietro Scicchitano, Luigi Laviola, Francesco Giorgino
Diabetic foot is a common complication in diabetes mellitus course, able to increase the overall morbidity/mortality risk of such a disease. The aim was to investigate the outcomes, the incidence of clinical events, the number of recurrent ulcers in patients with diabetic foot during 1 year follow-up after angioplasty (PTA) revascularization. From January 2007 to August 2009, 103 diabetic patients with diabetic foot undergoing revascularization of a lower limb by PTA were recruited. At 1 year follow-up we assessed: "major" (death, stroke, Myocardial Infaction (MI) and "minor" (Deep Vein Thrombosis (DVT), renal failure, restenosis) events incidence; recurrent ulcers incidence; the predictive elements of all these events...
August 15, 2012: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/23774953/discharge-after-primary-angioplasty-at-24-h-feasible-and-safe-or-a-step-too-far
#12
REVIEW
Ali Khavandi, Phillip Freeman, Pascal Meier
Current clinical practice regarding surveillance period and length of hospital stay after an ST elevation myocardial infarction is very variable among different countries and hospitals. In general, there has been a significant reduction in length of stay overall, which is mainly due to the increasing use of primary percutaneous coronary intervention. Length of stay after a ST elevation myocardial infaction, which is a rather common event, has a major impact on health care costs and patients' quality of life...
2013: Cardiology
https://www.readbyqxmd.com/read/23643079/-myocardial-regeneration-was-promoted-by-injected-oct4-adenovirus-eukaryotic-expression-vector
#13
Xuehui Zhang, Xiaogang Zhang, Ruofei Shi, Yanmei Dai, Chuan Chen
OBJECTIVE: To construct octamer-binding transcription factor-4 (Oct4) adenoviruse eukaryotic expression vector pAV.Ex1d.-CMV>mOCT4/IRES/eGFP, and study its effect on myocardial regeneration in mice. METHODS: We constructed eukaryotic expression vector pAV.Ex1d.-CMV>mOCT4/IRES/eGFP using Gateway(R);technology and then packaged the vector with adenoviruses. After adenovirus packaging, the vector was injected into the mouse myocardium by microsyringe. The expression of Oct4 was determined by the methods of immunofluorescence and RT-PCR, and hematoxylin-eosin (HE) staining was used to detect whether the myocardial tissue was changed after the expression of Oct4...
March 2013: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/22986554/serum-chitotriosidase-activity-in-acute-coronary-syndrome
#14
Bekir Serhat Yildiz, Burcu Barutcuoglu, Yusuf Izzettin Alihanoglu, Mustafa Beyazit Alkan, Murat Bilgin, Ilker Gul, Hasan Gungor, Fatma Esin, Ahmet Sayin, Mehdi Zoghi
AIM: Inflammation is a critical participant in mediating all stages of cardiovascular disease. Studies related with chitotriosidase that was recently found to be relevant to arterial inflammation. In this study we evaluated activity of serum chitotriosidase in acute coronary syndrome patients and its relationship with cardiovascular events, cardiac enzymes and inflammatory indicators. METHODS: We prospectively analyzed consecutive 30 patients with ST-segment elevation myocardial infarction, 30 patients with non ST-segment elevation myocardial infarction, 30 patients with unstable angina pectroris who were admitted to our intensive care unit and 30 healthy people (average age 56...
2013: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/22864326/-two-cases-of-acute-coronary-syndrome-after-intake-of-clavis-panax
#15
Aslı İnci Atar, Okan Er, Abdullah Güven, Beyhan Eryonucu
Atherosclerotic cardiovascular disease is an epidemic in today's world. It is one of the most common causes of hospitalization and death. Therefore, remedies to control or heal the disease are continuously sought. In addition to scientifically researched therapies, patients frequently utilize alternative medicine. However, effective and toxic doses, metabolisms, and drug interactions of the herbs and herbal nutrition supplements are largely unknown. Herein, we present two cases with acute coronary syndrome...
April 2012: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/22679732/-effects-of-the-proliferation-state-of-the-endothelial-progenitor-cells-preconditioned-with-salvianolic-acid-b-and-bone-marrow-mesenchymal-stem-cells-transplanted-in-acute-myocardial-infarction-rats
#16
Gui-Feng Zhao, Ying-Chang Fan, Xi-Juan Jiang
OBJECTIVE: To observe the proliferation state of transplanted cells in acute myocardial infarction (AMI) rats, and the endothelial progenitor cells (EPCs) preconditioned by salvianolic acid B in different ratios with the bone mesenchymal stem cells (BMSCs). METHODS: The cultivation and purification of EPCs were performed by density-gradient centrifugation and plastic adherence method. Two types of cells were identified by immunocytochemical method (CD34, CD133, and CD44)...
May 2012: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/20301034/-acute-coronary-syndrome-in-a-patient-with-wolff-parkinson-white-syndrome-a-case-report
#17
Paweł Dybich, Radosław Bartkowiak, Beata Wozakowska-Kapłon
A case of a 59-year-old man with acute coronary syndrome and ECG features of WPW syndrome is described. The typical chest pain and release of myocardial necrosis markers were accompanied by ECG signs of preexcitation. Angiography revealed significant lesions in coronary arteries. Difficulties in ECG diagnosis of acute myocardial infaction in the presence of preexicitation are disscussed.
February 2010: Kardiologia Polska
https://www.readbyqxmd.com/read/19918333/utility-of-desmin-and-a-masson-s-trichrome-method-to-detect-early-acute-myocardial-infarction-in-autopsy-tissues
#18
Jie Ouyang, Miguel Guzman, Fidelina Desoto-Lapaix, Matthew R Pincus, Rosemary Wieczorek
Detection of early acute myocardial ischemia/infarction prior to neutrophilic infiltration in autopsy myocardium poses a diagnostic dilemma to the surgical pathologist. Morphological changes can be subtle or not identified at all on the hematoxylin and eosin stain. To evaluate the Masson's trichrome stain and immunohistochemical stains, desmin and myoglobin, in detecting acute myocardial ischemia/infarction in autopsy myocardium. We reviewed the autopsy files of the New York Harbor Healthcare System and retrieved 25 cases of early acute myocardial infarction...
2009: International Journal of Clinical and Experimental Pathology
https://www.readbyqxmd.com/read/19484513/-relevance-of-magnetocardiography-in-coronary-artery-disease-and-myocardial-infarction
#19
B Hailer
Multichannel magnetocardiography (MCG) noninvasively registers the magnetic activity of the heart at different points above the thorax. This information can be used to determine the magnetic field produced by cardiac activity as well to reconstruct the current density distribution in the myocardium, which can then be examined during cardiac de- and repolarisation. First studies have shown that the detection of disease specific changes of the magnetic field and current density permit the diagnosis and localization of myocardial infaction (MI) and myocardial ischemia within the context of coronary artery disease (CAD)...
September 1997: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/19374048/-depression-and-myocardial-infaction
#20
A Testuz
Several works show an association between depression and the occurence of a first myocardial infarction. Depression after myocardial infarction seems to be a marker of poorer outcome, regardless of other risk factors or severity of the myocardial infarction. Dysautonomia and alteration of platelet activation are a few physiopathological changes shared by both affections, through which they might be related. Treatment of depression is not associated with better cardiovascular outcome, but selective serotonin reuptake inhibitors have been shown safe and efficient among patients with coronary heart disease...
March 4, 2009: Revue Médicale Suisse
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