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myocardial infaction

Holger M Nef, Jens Wiebe, Johannes Kastner, Julinda Mehilli, Thomas Münzel, Christoph Naber, Till Neumann, Gert Richardt, Axel Schmermund, Jochen Wöhrle, Ralf Zahn, Thomas Riemer, Stephan Achenbach, Christian W Hamm
AIMS: To analyze procedural results and mid-term safety of everolimus-eluting bioresorbable vascular scaffolds (BVS) used for percutaneous coronary intervention in a large all-comer cohort from the German-Austrian ABSORB Registry (GABI-R). METHODS AND RESULTS: A total of 3231 patients were included in this prospective, observational, multicentre study ( NCT02066623) of consecutive patients undergoing BVS implantation between November 2013 and January 2016...
August 22, 2017: EuroIntervention
J Liu, H B Yan, L Song, Y H Hua, H J Zhao, C Liu, P Zhou, J N Li, Y Tan, Y M Yang, Y Wu
Objective: To investigate the degree and determinants of using ticagrelor among discharged patients with acute coronary syndrome (ACS). Methods: Patients with ACS in Fuwai hospital who were given ticagrelor after discharge between Jan. 2015 to Jun. 2015 were analyzed.The clinical characteristics and adherence to ticagrelor of these patients were collected by reviewing the electronic medical records and telephone interview.Date were statistically-analyzed. Results: Among all screened 404 patients, 158 (39.1%) patients prematurely stopped ticagrelor within 12 months, while 119(29...
April 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Emese Lovadi, Péter Csécsei, Csenge Lovig, Zsófia Karádi, László Szapáry
Stroke is the third most common cause of death worldwide following myocardial infaction and malignancies, furthermore, its functional outcome is the worst of all conditions. Cholesterol, especially LDL-cholesterol plays a key role in the formation of atherosclerotic plaques. It has been verified recently that escalating incidence and mortality of cerebrovascular diseases are proportional to increased levels of LDL-cholesterol. Statin therapy undeniably reduces the risk of stroke, however other methods for decreasing lipid levels have not been proved significantly effective...
December 2016: Orvosi Hetilap
Matthias Dewenter, Michael Wagner, Ali El-Armouche
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
Samarjit Bisoyi, Anjan K Dash, Debashish Nayak, Satyajit Sahoo, Raghunath Mohapatra
Free wall rupture of the left ventricle (LV) is a rare but life-threatening complication of acute myocardial infaction. Very rarely such rupture may be contained by the adhering pericardium creating a pseudoaneurysm. This condition warrants for an emergency surgery. Left ventricular aneurysm is the discrete thinning of the ventricular wall (<5 mm) with akinetic or dyskinetic wall motion causing an out-pouching of the ventricle. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is important...
January 2016: Annals of Cardiac Anaesthesia
Zoran Stajić
INTRODUCTION: Stent entrapment and dislodgement in the coronary arteries is a rare but potentially fatal complication of percutaneous coronary intervention. Different retrival techniques of dislodged stents have previously been reported with high success rate but all of them are time-consuming, so as not quite useful in hemodinamically unstable patient. CASE REPORT: A 59-year old female patient with acute ST-elevation myocardial infaction of anterior wall was admitted for primary percutanous coronary intervention...
May 2015: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Ludimila Forechi, Marcelo Perim Baldo, Isabela Binotti de Araujo, Breno Valentim Nogueira, José Geraldo Mill
The dietary-sodium restriction is a standard approach following an acute myocardial infarction (MI). We examined the hypothesis in which the use of a high or low-sodium diet would worsen post-infarction left ventricular remodeling in rats and facilitate the development of heart failure. Left coronary artery ligation or sham-operated (SO) was produced in male Wistar rats (250-290 g). After surgery, animals were assigned to one of the three diets: standard amount of sodium (0.3% NaCl, SO and MI groups), a high-sodium diet (0...
February 2015: Journal of the American Society of Hypertension: JASH
Liang Chen, Hao Tang, Yan-Bing Liang, Zhi-Bin Chen, Zhen-Yu Li, Zi-Tong Huang, Long-Yuan Jiang, Zhong-Fu Ma
BACKGROUND: As the regulators of cytokines, suppressors of cytokine signaling (SOCS) play an important role in the inflammation reaction. Some studies found that SOCS-1 and SOCS-3 were involved in the pathogenesis of some inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease. But the expressions of SOCS in coronary heart disease have not yet been reported. This study aimed to investigate the expression and clinical significance of SOCS-1 and SOCS-3 in the myocardium of patients with sudden cardiac death (SCD)...
2010: World Journal of Emergency Medicine
Marco Matteo Ciccone, Alfredo Marchese, Aikaterini Generali, Cataldo Loiodice, Francesca Cortese, Rosa Carbonara, Pietro Scicchitano, Luigi Laviola, Francesco Giorgino
Diabetic foot is a common complication in diabetes mellitus course, able to increase the overall morbidity/mortality risk of such a disease. The aim was to investigate the outcomes, the incidence of clinical events, the number of recurrent ulcers in patients with diabetic foot during 1 year follow-up after angioplasty (PTA) revascularization. From January 2007 to August 2009, 103 diabetic patients with diabetic foot undergoing revascularization of a lower limb by PTA were recruited. At 1 year follow-up we assessed: "major" (death, stroke, Myocardial Infaction (MI) and "minor" (Deep Vein Thrombosis (DVT), renal failure, restenosis) events incidence; recurrent ulcers incidence; the predictive elements of all these events...
August 15, 2012: Pakistan Journal of Biological Sciences: PJBS
Ali Khavandi, Phillip Freeman, Pascal Meier
Current clinical practice regarding surveillance period and length of hospital stay after an ST elevation myocardial infarction is very variable among different countries and hospitals. In general, there has been a significant reduction in length of stay overall, which is mainly due to the increasing use of primary percutaneous coronary intervention. Length of stay after a ST elevation myocardial infaction, which is a rather common event, has a major impact on health care costs and patients' quality of life...
2013: Cardiology
Xuehui Zhang, Xiaogang Zhang, Ruofei Shi, Yanmei Dai, Chuan Chen
OBJECTIVE: To construct octamer-binding transcription factor-4 (Oct4) adenoviruse eukaryotic expression vector pAV.Ex1d.-CMV>mOCT4/IRES/eGFP, and study its effect on myocardial regeneration in mice. METHODS: We constructed eukaryotic expression vector pAV.Ex1d.-CMV>mOCT4/IRES/eGFP using Gateway(R);technology and then packaged the vector with adenoviruses. After adenovirus packaging, the vector was injected into the mouse myocardium by microsyringe. The expression of Oct4 was determined by the methods of immunofluorescence and RT-PCR, and hematoxylin-eosin (HE) staining was used to detect whether the myocardial tissue was changed after the expression of Oct4...
March 2013: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
Bekir Serhat Yildiz, Burcu Barutcuoglu, Yusuf Izzettin Alihanoglu, Mustafa Beyazit Alkan, Murat Bilgin, Ilker Gul, Hasan Gungor, Fatma Esin, Ahmet Sayin, Mehdi Zoghi
AIM: Inflammation is a critical participant in mediating all stages of cardiovascular disease. Studies related with chitotriosidase that was recently found to be relevant to arterial inflammation. In this study we evaluated activity of serum chitotriosidase in acute coronary syndrome patients and its relationship with cardiovascular events, cardiac enzymes and inflammatory indicators. METHODS: We prospectively analyzed consecutive 30 patients with ST-segment elevation myocardial infarction, 30 patients with non ST-segment elevation myocardial infarction, 30 patients with unstable angina pectroris who were admitted to our intensive care unit and 30 healthy people (average age 56...
2013: Journal of Atherosclerosis and Thrombosis
Aslı İnci Atar, Okan Er, Abdullah Güven, Beyhan Eryonucu
Atherosclerotic cardiovascular disease is an epidemic in today's world. It is one of the most common causes of hospitalization and death. Therefore, remedies to control or heal the disease are continuously sought. In addition to scientifically researched therapies, patients frequently utilize alternative medicine. However, effective and toxic doses, metabolisms, and drug interactions of the herbs and herbal nutrition supplements are largely unknown. Herein, we present two cases with acute coronary syndrome...
April 2012: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Gui-Feng Zhao, Ying-Chang Fan, Xi-Juan Jiang
OBJECTIVE: To observe the proliferation state of transplanted cells in acute myocardial infarction (AMI) rats, and the endothelial progenitor cells (EPCs) preconditioned by salvianolic acid B in different ratios with the bone mesenchymal stem cells (BMSCs). METHODS: The cultivation and purification of EPCs were performed by density-gradient centrifugation and plastic adherence method. Two types of cells were identified by immunocytochemical method (CD34, CD133, and CD44)...
May 2012: Chinese Journal of Integrated Traditional and Western Medicine
Paweł Dybich, Radosław Bartkowiak, Beata Wozakowska-Kapłon
A case of a 59-year-old man with acute coronary syndrome and ECG features of WPW syndrome is described. The typical chest pain and release of myocardial necrosis markers were accompanied by ECG signs of preexcitation. Angiography revealed significant lesions in coronary arteries. Difficulties in ECG diagnosis of acute myocardial infaction in the presence of preexicitation are disscussed.
February 2010: Kardiologia Polska
Jie Ouyang, Miguel Guzman, Fidelina Desoto-Lapaix, Matthew R Pincus, Rosemary Wieczorek
Detection of early acute myocardial ischemia/infarction prior to neutrophilic infiltration in autopsy myocardium poses a diagnostic dilemma to the surgical pathologist. Morphological changes can be subtle or not identified at all on the hematoxylin and eosin stain. To evaluate the Masson's trichrome stain and immunohistochemical stains, desmin and myoglobin, in detecting acute myocardial ischemia/infarction in autopsy myocardium. We reviewed the autopsy files of the New York Harbor Healthcare System and retrieved 25 cases of early acute myocardial infarction...
2009: International Journal of Clinical and Experimental Pathology
B Hailer
Multichannel magnetocardiography (MCG) noninvasively registers the magnetic activity of the heart at different points above the thorax. This information can be used to determine the magnetic field produced by cardiac activity as well to reconstruct the current density distribution in the myocardium, which can then be examined during cardiac de- and repolarisation. First studies have shown that the detection of disease specific changes of the magnetic field and current density permit the diagnosis and localization of myocardial infaction (MI) and myocardial ischemia within the context of coronary artery disease (CAD)...
September 1997: Herzschrittmachertherapie & Elektrophysiologie
A Testuz
Several works show an association between depression and the occurence of a first myocardial infarction. Depression after myocardial infarction seems to be a marker of poorer outcome, regardless of other risk factors or severity of the myocardial infarction. Dysautonomia and alteration of platelet activation are a few physiopathological changes shared by both affections, through which they might be related. Treatment of depression is not associated with better cardiovascular outcome, but selective serotonin reuptake inhibitors have been shown safe and efficient among patients with coronary heart disease...
March 4, 2009: Revue Médicale Suisse
Guifu Wu, Jamal S Rana, Joanna Wykrzykowska, Zhimin Du, Qingen Ke, Peter Kang, Jian Li, Roger J Laham
The mechanism of exercise-induced benefit and angiogenesis in ischemic heart disease remains poorly defined. This study was designed to investigate the effects of exercise training on the expression of angiogenic factors and angiogenesis in the infarcted myocardium [myocarial infaction (MI)]. Sixty-three male FVB mice were used for study and were divided into subgroups to test the response to exercise: the time-dependent expression of angiogenic factors to exercise training in normal (group 1; n = 12) and infarcted myocardium (group 2; n = 15) and the exercise-induced angiogenic response in normal and infarcted myocardium (group 3; n = 20) as well as the impact of exercise preconditioning on infarcted myocardium (group 4; n = 26)...
February 2009: American Journal of Physiology. Heart and Circulatory Physiology
Xin Jin, Yu-Cheng Chen, Wei-Qiang Liu, Hao-Yu Wang, Bin Wang, Zhi Zeng
OBJECTIVE: To study the influence of estradiol on myocardial angiogenesis and the expression of estrogen receptors in a rat model of myocardial infarction. METHODS: Acute myocardial infaction (AMI) model was established by ligation of left anterior descending coronary in ovariectomized SD rats, which then were treated with different doses of estradiol Benzoate. Estradiol concentration in serum was measured by Radioimmunoassay before AMI and 4 weeks later, microvascular density in myocardium was evaluated with detection of expression of VIII factor by Immunohistochemistry, and estrogen receptor alpha and beta protein in the myocardium were detected with Western blot at 28 d after AMI...
May 2008: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
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