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Vision glaucoma cataract macular degeneration

Eva K Fenwick, Peng Guan Ong, Ryan E K Man, Charumathi Sabanayagam, Ching-Yu Cheng, Tien Y Wong, Ecosse L Lamoureux
AIMS: To assess the relationship between vision impairment (VI) and major eye diseases, with vision-specific emotional well-being in a Chinese population. METHODS: In this population-based cross-sectional study, 3353 Chinese participants aged 40-80 years answered the emotional well-being scale of the Impact of Vision Impairment questionnaire, validated using Rasch analysis. Participants underwent visual acuity testing and collection of sociodemographic and medical data from standardised questionnaires...
August 26, 2016: British Journal of Ophthalmology
Adrienne W Scott, Neil M Bressler, Suzanne Ffolkes, John S Wittenborn, James Jorkasky
Importance: Understanding the importance of eye health to the US population across ethnic and racial groups helps guide strategies to preserve vision in Americans and inform policy makers regarding priority of eye research to Americans. Objective: To understand the importance and awareness of eye health in the US population across ethnic and racial groups. Design, Setting, and Participants: Online nationwide poll created by experienced policy makers in August 2014 designed to understand the importance of eye health in the US population, although the poll was not subjected previously to formal construct-validity testing...
October 1, 2016: JAMA Ophthalmology
Allen L Pelletier, Ledy Rojas-Roldan, Janis Coffin
Vision loss affects 37 million Americans older than 50 years and one in four who are older than 80 years. The U.S. Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for impaired visual acuity in adults older than 65 years. However, family physicians play a critical role in identifying persons who are at risk of vision loss, counseling patients, and referring patients for disease-specific treatment. The conditions that cause most cases of vision loss in older patients are age-related macular degeneration, glaucoma, ocular complications of diabetes mellitus, and age-related cataracts...
August 1, 2016: American Family Physician
Eva K Fenwick, Peng Guan Ong, Ryan Eyn Kidd Man, Ching-Yu Cheng, Charumathi Sabanayagam, Tien Y Wong, Ecosse L Lamoureux
Importance: Mobility limitations arising from vision impairment (VI) can result in loss of independence and reduced quality of life. However, few data are available on the association between VI and mobility limitations at a population-based level, particularly in Asian populations. Objective: To assess the association of VI and major eye diseases with mobility and independence (M&I) in a Chinese population. Design, Setting, and Participants: The Singapore Chinese Eye Study (February 9, 2009, to December 19, 2011) was a population-based, cross-sectional study of 3353 persons aged 40 to 80 years of Chinese ethnicity...
October 1, 2016: JAMA Ophthalmology
Mansing Ratanasukon, Jongjit Tongsomboon, Patama Bhurayanontachai, Pichai Jirarattanasopa
The objective of this study is to validate the Thai-version of the impact of vision impairment (IVI) questionnaire and to evaluate its impact on vision-related quality of life (VRQoL) in southern Thailand. The IVI questionnaire was translated into Thai according to WHO translation guidelines. In addition to the routine ophthalmological examinations, a Thai version of the IVI questionnaire was administered to all participants. A total of 120 patients with visual impairment who presented at Songklanagarind hospital, Songkhla province, were enrolled in the study; 30 had age-related macular degeneration (AMD), 30 had cataract, 30 had diabetic retinopathy, 30 had glaucoma, and 30 non-visually impaired individuals comprised the control group...
2016: PloS One
Olga Partyka, Mirosław J Wysocki
ADMISSION: Untreated eye diseases are the leading cause of blindness in the world. Most people suffering from visual impairment is in the age group above 50 years of age. As many as 82% of people in this group is suffering from eye diseases. OBJECTIVE: The aim of this work was to present the epidemiology of eye diseases and state of infrastructure of ophthalmology in Poland. MATERIAL AND METHODS: Based on data by WHO prepared review of world and Polish literature on issues in the field of ophthalmology and epidemiology of eye diseases...
2015: Przegla̧d Epidemiologiczny
Allison C Umfress, Milam A Brantley
The elderly population in the United States (age 65 and older) is growing rapidly, estimated by the U.S. Census Department to reach 83.7 million by 2050.(1) Visual impairment increases with age among all racial and ethnic groups.(2) In the elderly, the most common culprits for vision loss are cataract, glaucoma, and age-related macular degeneration (AMD).(2) In the developed world, vision loss from cataract has been dramatically reduced by increased access to cataract surgery. However, AMD and glaucoma lead to irreversible vision loss without early diagnosis and intervention...
2016: Seminars in Ophthalmology
Chee Wai Wong, Ecosse L Lamoureux, Ching-Yu Cheng, Gemmy Chui Ming Cheung, E Shyong Tai, Tien Y Wong, Charumathi Sabanayagam
BACKGROUND: Chronic kidney disease (CKD) has been shown to be associated with diabetic retinopathy (DR) and age-related macular degeneration (AMD), leading causes of blindness in elderly adults in previous studies. However, the association of CKD with visual impairment (VI) is not clear. We aimed to examine the association of CKD with VI and other age-related ocular diseases in a population-based sample of Asian adults. METHODS: We analyzed data from 10,033 adults aged 40-80 years who participated in the Singapore Epidemiology of Eye Diseases (SEED, 2004-11) Study...
March 2016: EBioMedicine
Khaled K Abu-Amero, Altaf A Kondkar, Kakarla V Chalam
Resveratrol, a naturally occurring plant polyphenol found in grapes, is the principal biologically active component in red wine. Clinical studies have shown that resveratrol due to its potent anti-oxidant and anti-inflammatory properties are cardio-protective, chemotherapeutic, neuroprotective, and display anti-aging effects. Oxidative stress and inflammation play a critical role in the initiation and progression of age-related ocular diseases (glaucoma, cataract, diabetic retinopathy and macular degeneration) that lead to progressive loss of vision and blindness...
2016: Nutrients
María D Pinazo-Durán, Vicente Zanón-Moreno, José J García-Medina, J Fernando Arévalo, Roberto Gallego-Pinazo, Carlo Nucci
Coexistence of several ocular diseases is more frequent than suspected. In spite of the refractive errors, one or more of the following can be detected simultaneously: glaucoma, cataracts, uveitis, age-related macular degeneration, and dry eyes. In addition, as people age, ocular comorbidities are much more usually seen. Specific diseases are openly acknowledged to affect the eyes and vision, such as diabetes mellitus, hypertension blood pressure, arthritis, hyperthyroidism, neurodegenerative disorders, hematologic malignancies, and/or systemic infections...
2016: BioMed Research International
Jonathan P Giblin, Nuria Comes, Olaf Strauss, Xavier Gasull
The eye is the sensory organ of vision. There, the retina transforms photons into electrical signals that are sent to higher brain areas to produce visual sensations. In the light path to the retina, different types of cells and tissues are involved in maintaining the transparency of avascular structures like the cornea or lens, while others, like the retinal pigment epithelium, have a critical role in the maintenance of photoreceptor function by regenerating the visual pigment. Here, we have reviewed the roles of different ion channels expressed in ocular tissues (cornea, conjunctiva and neurons innervating the ocular surface, lens, retina, retinal pigment epithelium, and the inflow and outflow systems of the aqueous humor) that are involved in ocular disease pathophysiologies and those whose deletion or pharmacological modulation leads to specific diseases of the eye...
2016: Advances in Protein Chemistry and Structural Biology
Shuchi Gulati, Zélia M Corrêa, Nagla Karim, Stephen Medlin
CONTEXT: Elderly patients with visual loss often have age-related macular degeneration, diabetic retinopathy, glaucoma, and cataract as common causes of visual loss. Other less common etiologies should be considered, especially in those presenting with systemic associations. CASE REPORT: The patient discussed in our review is an 80-year-old female, with a history of diabetic retinopathy and macular degeneration who presented with a sudden deterioration of vision...
January 2016: North American Journal of Medical Sciences
Christophe Boudry, Eric Denion, Bruno Mortemousque, Fréderic Mouriaux
BACKGROUND: The purpose of this study is to provide a report on scientific production during the period 2010-2014 in order to identify the major topics as well as the predominant actors (journals, countries, continents) involved in the field of eye disease. METHODS: A PubMed search was carried out to extract articles related to eye diseases during the period 2010-2014. Data were downloaded and processed through developed PHP scripts for further analysis. RESULTS: A total of 62,123 articles were retrieved...
2016: PeerJ
Scott McCusker, Maju Mathew Koola
OBJECTIVE: To review the prevalence of depression in common ophthalmologic disorders in the elderly and provide insight into treatment. DATA SOURCES: PubMed, Google Scholar, and DynaMed were searched using the terms depression and ophthalmology in combination with depression, mood disorders, cataracts, vision loss, age-related macular degeneration, primary open-angle glaucoma, and Fuchs corneal dystrophy. Articles were limited to those published in the English language between 1993 and 2013...
2015: Primary Care Companion to CNS Disorders
Kyung Chul Yoon, Won Choi, Hyo Seok Lee, Sang-Duck Kim, Seung-Hyun Kim, Chan Yun Kim, Ki Ho Park, Young Jeung Park, Seung-Hee Baek, Su Jeong Song, Jae Pil Shin, Suk-Woo Yang, Seung-Young Yu, Jong Soo Lee, Key Hwan Lim, Kyung Won Oh, Se Woong Kang
The Korea National Health and Nutrition Examination Survey (KNHANES) is a national program designed to assess the health and nutritional status of the noninstitutionalized population of South Korea. The KNHANES was initiated in 1998 and has been conducted annually since 2007. Starting in the latter half of 2008, ophthalmologic examinations were included in the survey in order to investigate the prevalence and risk factors of common eye diseases such as visual impairment, refractive errors, strabismus, blepharoptosis, cataract, pterygium, diabetic retinopathy, age-related macular degeneration, glaucoma, dry eye disease, and color vision deficiency...
December 2015: Korean Journal of Ophthalmology: KJO
Hannah E Bowrey, David M Anderson, Patrick Pallitto, Danielle B Gutierrez, Jie Fan, Rosalie K Crouch, Kevin L Schey, Zsolt Ablonczy
Visual sensation is fundamental for quality of life, and loss of vision to retinal degeneration is a debilitating condition. The eye is the only part of the central nervous system that can be noninvasively observed with optical imaging. In the clinics, various spectroscopic methods provide high spatial resolution images of the fundus and the developing degenerative lesions. However, the currently utilized tools are not specific enough to establish the molecular underpinnings of retinal diseases. In contrast, mass spectrometric imaging (MSI) is a powerful tool to identify molecularly specific disease indicators and classification markers...
April 2016: Proteomics. Clinical Applications
Marcel V Alavi
Aging involves defined genetic, biochemical and cellular pathways that regulate lifespan. These pathways are called longevity pathways and they have relevance for many age-related diseases. In the eye, longevity pathways are involved in the major blinding diseases, cataract, glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy. Pharmaceutical targeting of longevity pathways can extend healthy lifespan in laboratory model systems. This offers the possibility of therapeutic interventions to also delay onset or slow the progression of age-related eye diseases...
2016: Advances in Experimental Medicine and Biology
Bojan Kovac, Miroslav Vukosavljevic, Jelena Djokic Kovac, Mirko Resan, Goran Trajkovic, Janko Jankovic, Milena Smiljanic, Anita Grgurevic
PURPOSE: To test the validity and reliability of the Serbian version of the interviewer-administered format of the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25). METHODS: The Serbian version of NEI VFQ-25 was translated in accordance with standard methods that have been adopted internationally. In order to assess the reliability and validity of the translated NEI VFQ-25, we used a sample of 105 patients with four different chronic ocular diseases...
2015: Health and Quality of Life Outcomes
Ebru C Hamzaoglu, Michael D Straiko, Zachary M Mayko, Christopher S Sáles, Mark A Terry
PURPOSE: To compare results of the first 100 eyes of Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) that were performed with a standardized technique at a single institution. DESIGN: Single-center, retrospective case series. PARTICIPANTS: The first 100 eyes of standardized DSAEK and DMEK that underwent surgery for Fuchs corneal dystrophy at our center. We excluded patients with prior ocular surgery other than cataract surgery to limit confounding variables...
November 2015: Ophthalmology
Hans Limburg, Rosario Espinoza, Van C Lansingh, Juan Carlos Silva
OBJECTIVE: To review data on functional low vision (FLV) (low vision-visual acuity (VA) < 6/18 (<20/60) to > perception of light (PL+) in the better eye-that is untreatable and uncorrectable) in adults aged 50 years or older from published population-based surveys from 15 countries in Latin America and the Caribbean. METHODS: Data from 15 cross-sectional, population-based surveys on blindness and visual impairment (10 national and five subnational) covering 55 643 people > 50 years old in 15 countries from 2003 to 2013 were reanalyzed to extract statistics on FLV...
June 2015: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
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