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https://www.readbyqxmd.com/read/28813029/joint-mobile-data-collection-and-wireless-energy-transfer-in-wireless-rechargeable-sensor-networks
#1
Ping Zhong, Ya-Ting Li, Wei-Rong Liu, Gui-Hua Duan, Ying-Wen Chen, Neal Xiong
In wireless rechargeable sensor networks (WRSNs), there is a way to use mobile vehicles to charge node and collect data. It is a rational pattern to use two types of vehicles, one is for energy charging, and the other is for data collecting. These two types of vehicles, data collection vehicles (DCVs) and wireless charging vehicles (WCVs), are employed to achieve high efficiency in both data gathering and energy consumption. To handle the complex scheduling problem of multiple vehicles in large-scale networks, a twice-partition algorithm based on center points is proposed to divide the network into several parts...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28795294/how-long-does-antimycobacterial-antibiotic-loaded-bone-cement-have-in-vitro-activity-for-musculoskeletal-tuberculosis
#2
Jae Hoo Lee, Chang Dong Han, Sang-Nae Cho, Ick Hwan Yang, Woo Suk Lee, Seung-Hun Baek, Jae Won Shin, Khalid Elfadil Ibrahim Husein, Kwan Kyu Park
BACKGROUND: Antibiotic-loaded bone cement is accepted as an effective treatment modality for musculoskeletal tuberculosis. However, comparative information regarding combinations and concentrations of second-line antimycobacterial drugs, such as streptomycin and amoxicillin and clavulanic acid, are lacking. QUESTIONS/PURPOSES: (1) In antibiotic-loaded cement, is there effective elution of streptomycin and Augmentin(®) (amoxicillin and clavulanic acid) individually and in combination? (2) What is the antibacterial activity duration for streptomycin- and amoxicillin and clavulanic acid -loaded cement? METHODS: Six different types of bone cement discs were created by mixing 40 g bone cement with 1 or 2 g streptomycin only, 0...
August 9, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28763113/distribution-of-cardiac-troponin-i-in-the-japanese-general-population-and-factors-influencing-its-concentrations
#3
Naoya Abe, Kenichiro Tomita, Mayumi Teshima, Maki Kuwabara, Satoshi Sugawa, Nae Hinata, Masaaki Matsuura, Mutsunori Fujiwara, Kazuhiko Takaya, Toru Hiyoshi, Hiroki Uozumi, Hiroshi Ikenouchi, Rie Ishikawa, Junko Shojima, Junko Komatsu
BACKGROUND: The 99th percentile of cardiac troponin I level in the general population is accepted as the cut-off for the diagnosis of acute myocardial infarction (AMI). However, it is not clear whether the cut-offs derived in racially and geographically different populations are applicable in Japan. METHODS: Troponin I was determined using the Abbott ARCHITECT STAT high-sensitive troponin I immunoassay in 698 apparently healthy individuals who visited the Japanese Red Cross Medical Center for a health checkup...
August 1, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28759398/early-sign-language-exposure-and-cochlear-implantation-benefits
#4
Ann E Geers, Christine M Mitchell, Andrea Warner-Czyz, Nae-Yuh Wang, Laurie S Eisenberg
BACKGROUND: Most children with hearing loss who receive cochlear implants (CI) learn spoken language, and parents must choose early on whether to use sign language to accompany speech at home. We address whether parents' use of sign language before and after CI positively influences auditory-only speech recognition, speech intelligibility, spoken language, and reading outcomes. METHODS: Three groups of children with CIs from a nationwide database who differed in the duration of early sign language exposure provided in their homes were compared in their progress through elementary grades...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28752079/unique-chemokine-profiles-of-lung-tissues-distinguish-post-chemotherapeutic-persistent-and-chronic-tuberculosis-in-a-mouse-model
#5
Soomin Park, Seung-Hun Baek, Sang-Nae Cho, Young-Saeng Jang, Ahreum Kim, In-Hong Choi
There is a substantial need for biomarkers to distinguish latent stage from active Mycobacterium tuberculosis infections, for predicting disease progression. To induce the reactivation of tuberculosis, we present a new experimental animal model modified based on the previous model established by our group. In the new model, the reactivation of tuberculosis is induced without administration of immunosuppressive agents, which might disturb immune responses. To identify the immunological status of the persistent and chronic stages, we analyzed immunological genes in lung tissues from mice infected with M...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28731602/accuracy-and-precision-of-estimation-equations-to-predict-net-endogenous-acid-excretion-using-the-australian-food-database
#6
Benjamin H Parmenter, Gary J Slater, Lynda A Frassetto
AIM: The gold standard of measurement for net endogenous acid production (NEAP) is net acid excretion (NAE), a test that is not readily available, and consequently, estimative equations by Remer and Manz and Frassetto et al. are often used. These equations rely on nutrient databases and it is recommended that their validity be assessed using a country's database before their application in research in that country. We sought to delineate the accuracy and precision of these estimation equations using the Australian food database...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731600/spot-testing-urine-ph-a-novel-dietary-biomarker-a-randomised-cross-over-trial
#7
Benjamin H Parmenter, Gary J Slater, Lynda A Frassetto
AIM: Spot-tests of urine pH are claimed to be an accessible biomarker of net acid excretion (NAE), and as such, they may be able to determine changes in an individual's intake of acid- or base-forming foods. To test this hypothesis, we aimed to determine if spot-tests of urine pH could index NAE and relay the consumption of a fruit and vegetable (F&V) concentrate whilst determining this concentrate's capacity to modulate NAE. METHODS: In a double blind, placebo-controlled, cross-over trial, healthy adults (n = 13) were allocated by simple randomisation to receive a F&V concentrate or placebo for three days each, with diet standardised throughout...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28730283/blockade-of-alcohol-escalation-and-relapse-drinking-by-pharmacological-faah-inhibition-in-male-and-female-c57bl-6j-mice
#8
Yan Zhou, Benjamin I Schwartz, Joanna Giza, Steven S Gross, Francis S Lee, Mary Jeanne Kreek
BACKGROUND: Anandamide (AEA)-dependent signaling is regulated by the catabolic enzyme fatty acid amide hydrolase (FAAH). Several lines of evidence have demonstrated that FAAH and AEA are involved in the behavioral effects of alcohol. Therefore, we investigated whether a selective FAAH inhibitor, URB597 (cyclohexylcarbamic acid 3'-[aminocarbonyl]-[1,1'-biphenyl]-3-yl ester), altered alcohol intake in mice in a voluntary alcohol drinking model. METHODS: Mice, subjected to 3 weeks of chronic intermittent access (IA) in a two-bottle choice paradigm with 24-h access every other day, developed rapid escalation of alcohol intake and high preference...
July 20, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28723216/lycopene-inhibits-metastasis-of-human-liver-adenocarcinoma-sk-hep-1-cells-by-downregulation-of-nadph-oxidase-4-protein-expression
#9
Bo-Yi Jhou, Tuzz-Ying Song, Inn Lee, Miao-Lin Hu, Nae-Cherng Yang
NADPH oxidase 4 (NOX4), with the sole function to produce reactive oxygen species (ROS), can be a molecular target for disrupting cancer metastasis. Several studies have indicated that lycopene exhibited anti-metastatic actions in vitro and in vivo. However, the role of NOX4 in the anti-metastatic action of lycopene remains unknown. Herein, we first confirmed the anti-metastatic effect of lycopene (0.1-5 μM) on human liver adenocarcinoma SK-Hep-1 cells. We showed that lycopene significantly inhibited NOX4 protein expression, with the strongest inhibition of 64...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28703882/centrifugal-lithography-self-shaping-of-polymer-microstructures-encapsulating-biopharmaceutics-by-centrifuging-polymer-drops
#10
Huisuk Yang, Suyong Kim, Geonwoo Kang, Shayan F Lahiji, Mingyu Jang, Young Mi Kim, Jae-Myung Kim, Sang-Nae Cho, Hyungil Jung
Polymeric microstructures encapsulating biopharmaceutics must be fabricated in a controlled environment to preserve the biological activity. There is increasing demand for simple methods designed to preserve the biological activity by utilizing the natural properties of polymers. Here, the paper shows that centrifugal lithography (CL) can be used for the fabrication of such microstructures in a single centrifugation, by engineering the self-shaping properties of hyaluronic acid (HA). In this method, HA drops are self-shaped into hourglass-microstructures to produce two dissolving microneedles (DMN), which facilitate transdermal delivery via implantation on the skin...
July 13, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28693300/investigation-of-bovine-tuberculosis-outbreaks-using-the-trace-back-system-and-molecular-typing-in-korean-hanwoo-beef-cattle
#11
Bok Kyung Ku, Bo-Young Jeon, Jae Myung Kim, Young-Boo Jang, Hyeyoung Lee, Jae Young Choi, Suk Chan Jung, Hyang-Mi Nam, Hun Park, Sang-Nae Cho
Bovine tuberculosis is a chronic contagious disease responsible for major agricultural economic losses. Abattoir monitoring and trace-back systems are an appropriate method to control bovine tuberculosis, particularly in beef cattle. In the present study, a trace-back system was applied to bovine tuberculosis outbreaks of Korean native Hanwoo beef cattle. Bovine tuberculosis was detected in three index beef cattle during abattoir monitoring in Jeonbuk Province, Korea, and the original herds were traced back from each index cattle...
July 10, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28689299/4-o-methylhonokiol-protects-from-alcohol-carbon-tetrachloride-induced-liver-injury-in-mice
#12
Eleonora Patsenker, Andrea Chicca, Vanessa Petrucci, Sheida Moghadamrad, Andrea de Gottardi, Jochen Hampe, Jürg Gertsch, Nasser Semmo, Felix Stickel
Alcoholic liver disease (ALD) is a leading cause of liver cirrhosis, liver cancer, and related mortality. The endocannabinoid system contributes to the development of chronic liver diseases, where cannabinoid receptor 2 (CB2) has been shown to have a protecting role. Thus, here, we investigated how CB2 agonism by 4'-O-methylhonokiol (MHK), a biphenyl from Magnolia grandiflora, affects chronic alcohol-induced liver fibrosis and damage in mice. A combination of alcohol (10% vol/vol) and CCl4 (1 ml/kg) was applied to C57BL/6 mice for 5 weeks...
July 8, 2017: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/28682679/influence-of-epidemiologic-and-patient-behavior-related-predictors-on-amputation-rates-in-diabetic-patients-systematic-review-and-meta-analysis
#13
Jin Yong Shin, Si-Gyun Roh, Nae-Ho Lee, Kyung-Moo Yang
Amputation of patients with diabetic foot is a major issue worldwide, particularly from a medical and economic standpoint. This meta-analysis aimed to identify significant risk factors of high amputation rate among epidemiologic and patient behavior-related predictors in diabetic patients. A systematic literature review and meta-analysis were performed using MEDLINE, EMBASE, and Cochrane databases. Seven variables were extracted from the included studies and evaluated based on amputation rate. The Newcastle-Ottawa scale was used to assess the quality of the studies...
March 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28669728/targeting-neddylation-pathway-with-mln4924-pevonedistat-induces-noxa-dependent-apoptosis-in-renal-cell-carcinoma
#14
Jiyou Wang, Shiwen Wang, Wenjuan Zhang, Xiaofang Wang, Xiaojun Liu, Liang Liu, Lihui Li, Yupei Liang, Jinha Yu, Lak Shin Jeong, Lijun Jia, Hu Zhao, Yanmei Zhang
Inhibition of protein neddylation pathway has emerged an attractive anticancer strategy in preclinical studies by using Nedd8-activating enzyme (NAE) inhibitor MLN4924 (Pevonedistat). Previous studies have reported the antitumor activity of MLN4924 mediated by its efficacy on apoptosis, autophagy and senescence. However, whether MLN4924 has any effect on renal carcinoma cells (RCC) remains unexplored. Here we reported that MLN4924 specifically inhibited protein neddylation pathway, leading to statistically significantly suppress the proliferation, survival and migration of RCC cells by inducing G2 cell-cycle arrest, followed by apoptosis in a MLN4924 dose-dependent manner...
June 29, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28669139/is-alanine-aminotransferase-flare-up-in-nucleos-t-ide-analogue-treatment-of-chronic-hepatitis-b-a-promising-rather-than-a-devastating-sign
#15
Nae-Yun Heo
No abstract text is available yet for this article.
June 2017: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/28665851/demarcative-necrosis-along-previous-laceration-line-after-filler-injection
#16
Jong-Lim Kim, Jin Yong Shin, Si-Gyun Roh, Nae-Ho Lee
In recent years, fillers have been widely used for soft tissue augmentation. Although they are generally considered to be safe, many complications have been reported to date. Nose and nasolabial fold augmentations with fillers can lead to an implementation of nasal skin necrosis, possibly caused by intravascular embolism and/or extravascular compression. Herein, we present a case of a successfully treated patient who experienced skin necrosis after an injection of dermal fillers into the nasolabial fold. Interestingly, we discovered that the patient had experienced a laceration 8 years ago around the area in which the filler was injected...
June 29, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28665150/association-between-plasma-n-acylethanolamides-and-high-hemoglobin-concentration-in-southern-peruvian-highlanders
#17
Dulce E Alarcón-Yaquetto, Lidia Caballero, Gustavo F Gonzales
Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 00:000-000, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechanisms. Failing to adapt to chronic HA exposure leads to a disease called chronic mountain sickness (CMS) characterized by excessive erythrocytosis (hemoglobin [Hb] ≥19 g/dL for women and ≥21 g/dL for men)...
June 30, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28647205/measurement-properties-of-visual-rating-of-postural-orientation-errors-of-the-lower-extremity-a-systematic-review-and-meta-analysis
#18
REVIEW
Jenny Nae, Mark W Creaby, Anna Cronström, Eva Ageberg
OBJECTIVES: To systematically review measurement properties of visual assessment and rating of Postural Orientation Errors (POEs) in participants with or without lower extremity musculoskeletal disorders. METHODS: A systematic review according to the PRISMA guidelines was conducted. The search was performed in Medline (Pubmed), CINAHL and EMBASE (OVID) databases until August 2016. Studies reporting measurement properties for visual rating of postural orientation during the performance of weight-bearing functional tasks were included...
April 18, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28640096/effect-of-transforaminal-epidural-polydeoxyribonucleotide-injections-on-lumbosacral-radiculopathy-a-case-report
#19
Keum Nae Kang, Tae Woong Kim, Jin Woo Koh, Han Byeol Oh, Jong-Uk Mun, Mi Sook Seo, Young Uk Kim
RATIONALE: Transforaminal epidural glucocorticoids administration is widely performed for the management of lumbosacral radiculopathy. However, it may worsen the condition of patients with type 2 diabetes mellitus (DM). Polydeoxyribonucleotide (PDRN) was recently noted as a substitute for glucocorticoids. PATIENT CONCERNS: A 44-year-old male patient was admitted to our pain clinic with symptoms of low back pain with severe pain and tingling sensation of left posterolateral leg...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28636231/orchestration-at-the-beginning-mitosis-in-sea-urchin-embryo
#20
Giselle A Abruzzese, Nae Tanpradit, Renata S Tavares
Development of multicellular organisms is driven by a series of mitotic divisions after fertilization. Total cytoplasmic volume does not increase during this process, resulting in an increasing number of smaller daughter cells. Cell divisions are initially synchronous in an early embryo, but this ends at the 16-cell stage in the sea urchin. Orchesterated mitosis does, however, continue in subpopulations via the coordination of two different processes: karyokinesis and cytokinesis. Part of this asynchrony is due to the differentiation of lineages...
June 21, 2017: Molecular Reproduction and Development
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