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https://www.readbyqxmd.com/read/27867473/the-role-of-hydrogen-sulfide-in-stroke
#1
REVIEW
Yang Dou, Zhong Wang, Gang Chen
Stroke is a kind of acute cerebrovascular disease characterized by the focal lack of neurological function, including ischemic stroke and hemorrhagic stroke. As society ages rapidly, stroke has become the second leading cause of disability and death, and also become the main threat to human health and life. In recent years, findings from increasing animal and clinical trials have supplied scientific evidences for the treatment of stroke. Hydrogen sulfide (H2S), which has always been seen as a toxic gas, now has been thought to be the third gaseous signaling molecule following nitric oxide and carbon monoxide...
April 2016: Medical Gas Research
https://www.readbyqxmd.com/read/27849158/neurological-injury-in-intermediate-risk-transcatheter-aortic-valve-implantation
#2
Jonathon P Fanning, Allan J Wesley, Darren L Walters, Eamonn M Eeles, Adrian G Barnett, David G Platts, Andrew J Clarke, Andrew A Wong, Wendy E Strugnell, Cliona O'Sullivan, Oystein Tronstad, John F Fraser
BACKGROUND: The application of transcatheter aortic valve implantation (TAVI) to intermediate-risk patients is a controversial issue. Of concern, neurological injury in this group remains poorly defined. Among high-risk and inoperable patients, subclinical injury is reported on average in 75% undergoing the procedure. Although this attendant risk may be acceptable in higher-risk patients, it may not be so in those of lower risk. METHODS AND RESULTS: Forty patients undergoing TAVI with the Edwards SAPIEN-XT(™) prosthesis were prospectively studied...
November 15, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27810402/impact-of-intermittent-fasting-on-health-and-disease-processes
#3
REVIEW
Mark P Mattson, Valter D Longo, Michelle Harvie
Humans in modern societies typically consume food at least three times daily, while laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns often leads to metabolic morbidities (insulin resistance, excessive accumulation of visceral fat, etc.), particularly when associated with a sedentary lifestyle. Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enabled them to function at a high level, both physically and cognitively, when in a food-deprived/fasted state...
October 31, 2016: Ageing Research Reviews
https://www.readbyqxmd.com/read/27776697/perioperative-and-long-term-impact-of-chronic-kidney-disease-on-carotid-artery-interventions
#4
Derek Klarin, Robert T Lancaster, Emel Ergul, Daniel Bertges, Philip Goodney, Marc L Schermerhorn, Richard P Cambria, Virendra I Patel
OBJECTIVE: Chronic kidney disease (CKD) increases morbidity and mortality after vascular procedures and adversely affects late survival of patients. The presence of CKD also confers increased risk of stroke in patients with asymptomatic carotid stenosis. Patients undergoing carotid intervention in the Vascular Study Group of New England database were stratified by CKD status referable to periprocedural and late outcomes. METHODS: All carotid artery stenting and carotid endarterectomies (CEAs) performed from 2003 to 2013 were stratified by CKD severity as mild (estimated glomerular filtration rate [eGFR] >60 mL/min/1...
November 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27751555/validation-and-comparison-of-imaging-based-scores-for-prediction-of-early-stroke-risk-after-transient-ischaemic-attack-a-pooled-analysis-of-individual-patient-data-from-cohort-studies
#5
Peter J Kelly, Gregory W Albers, Anastasios Chatzikonstantinou, Gian Marco De Marchis, Julia Ferrari, Paul George, Mira Katan, Michael Knoflach, Jong S Kim, Linxin Li, Eun-Jae Lee, Jean-Marc Olivot, Francisco Purroy, Nicolas Raposo, Peter M Rothwell, Vijay K Sharma, Bo Song, Georgios Tsivgoulis, Cathal Walsh, Yuming Xu, Aine Merwick
BACKGROUND: Identification of patients at highest risk of early stroke after transient ischaemic attack has been improved with imaging based scores. We aimed to compare the validity and prognostic utility of imaging-based stroke risk scores in patients after transient ischaemic attack. METHODS: We did a pooled analysis of published and unpublished individual-patient data from 16 cohort studies of transient ischaemic attack done in Asia, Europe, and the USA, with early brain and vascular imaging and follow up...
November 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27734820/-brain-stroke-risk-of-disability-and-possibilities-of-improvment-in-motor-and-cognitive-functioning
#6
Michał Starosta, Justyna Redlicka, Michał Brzeziański, Marta Niwald, Elżbieta Miller
Diseases of the central nervous system are the most common cause of mobility and cognitive impairment. Stroke is the leading cause of hospitalization in the Neurological Rehabilitation Departments. Age increases the risk of stroke, therefore monitoring basic medical parameters, including blood pressure especially under age of 65, is a very important part of preventive healthcare. According to data from the National Association of Stroke, in 10% of patients after brain stroke, recovery of motor functions and mental state is almost complete, in 25% impairment is minimal, in 40% the functional and cognitive disability is moderated or significant therefore requires rehabilitation, in 10% in view of impossibility of active rehabilitation patients requires comprehensive nursing care service at home or in special long term care centers...
July 29, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27692902/dnm3-and-genetic-modifiers-of-age-of-onset-in-lrrk2-gly2019ser-parkinsonism-a-genome-wide-linkage-and-association-study
#7
Joanne Trinh, Emil K Gustavsson, Carles Vilariño-Güell, Stephanie Bortnick, Jeanne Latourelle, Marna B McKenzie, Chelsea Szu Tu, Ekaterina Nosova, Jaskaran Khinda, Austen Milnerwood, Suzanne Lesage, Alexis Brice, Meriem Tazir, Jan O Aasly, Laura Parkkinen, Hazal Haytural, Tatiana Foroud, Richard H Myers, Samia Ben Sassi, Emna Hentati, Fatma Nabli, Emna Farhat, Rim Amouri, Fayçal Hentati, Matthew J Farrer
BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) mutation 6055G→A (Gly2019Ser) accounts for roughly 1% of patients with Parkinson's disease in white populations, 13-30% in Ashkenazi Jewish populations, and 30-40% in North African Arab-Berber populations, although age of onset is variable. Some carriers have early-onset parkinsonism, whereas others remain asymptomatic despite advanced age. We aimed to use a genome-wide approach to identify genetic variability that directly affects LRRK2 Gly2019Ser penetrance...
November 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27610118/society-of-vascular-and-interventional-neurology-svin-stroke-interventional-laboratory-consensus-silc-criteria-a-7m-management-approach-to-developing-a-stroke-interventional-laboratory-in-the-era-of-stroke-thrombectomy-for-large-vessel-occlusions
#8
Tanzila Shams, Osama Zaidat, Dileep Yavagal, Andrew Xavier, Tudor Jovin, Vallabh Janardhan
Brain attack care is rapidly evolving with cutting-edge stroke interventions similar to the growth of heart attack care with cardiac interventions in the last two decades. As the field of stroke intervention is growing exponentially globally, there is clearly an unmet need to standardize stroke interventional laboratories for safe, effective, and timely stroke care. Towards this goal, the Society of Vascular and Interventional Neurology (SVIN) Writing Committee has developed the Stroke Interventional Laboratory Consensus (SILC) criteria using a 7M management approach for the development and standardization of each stroke interventional laboratory within stroke centers...
June 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27532657/effectiveness-of-allied-health-therapy-in-the-symptomatic-management-of-progressive-supranuclear-palsy-a-systematic-review
#9
Erica Tilley, James McLoughlin, Simon A Koblar, Sebastian H Doeltgen, Cindy Stern, Sarahlouise White, Micah D J Peters
BACKGROUND: Progressive supranuclear palsy (PSP) is an adult onset neurodegenerative condition associated with mobility, balance, speech, swallowing, vision and cognitive changes. The condition is diagnosed using the National Institute for Neurological Disorders and Stroke (NINDS) and the Society of Progressive Supranuclear Palsy (SPSP) criteria. Therapeutic interventions for PSP are important, and a healthcare team should include a physiotherapist, occupational therapist and speech therapist...
June 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27529284/standardization-of-data-for-clinical-use-and-research-in-spinal-cord-injury
#10
REVIEW
Fin Biering-Sørensen, Vanessa K Noonan
Increased survival after spinal cord injury (SCI) worldwide has enhanced the need for quality data that can be compared and shared between centers, countries, as well as across research studies, to better understand how best to prevent and treat SCI. Such data should be standardized and be able to be uniformly collected at any SCI center or within any SCI study. Standardization will make it possible to collect information from larger SCI populations for multi-center research studies. With this aim, the international SCI community has obtained consensus regarding the best available data and measures for use in SCI clinical practice and research...
August 12, 2016: Brain Sciences
https://www.readbyqxmd.com/read/27440686/a-survey-of-the-enteral-nutrition-practices-in-patients-with-neurological-disorders-in-the-tertiary-hospitals-of-china
#11
Ying-Ying Su, Dai-Quan Gao, Xiao-Yan Zeng, Rui-Juan Sha, Xiao-Yuan Niu, Chang-Qing Wang, Dong Zhou, Wen Jiang, Fang Cui, Yi Yang, Su-Yue Pan, Xu Zhang, Lian-Di Li, Liang Gao, Bin Peng, Chun-Long Zhong, Zhen-Chuan Liu, Li-Hong Li, Hong Tan, Pei-Yuan Lv
BACKGROUND AND OBJECTIVES: With the development of enteral nutrition in patients with neurological disorders in China, related guidelines were published in 2011. The Chinese Society for Parenteral and Enteral Nutrition conducted a survey to evaluate the status quo of enteral nutrition practices in these patients. METHODS AND STUDY DESIGN: This multicenter prospective investigation was conducted from April 2012 to April 2013 and involved 18 tertiary hospitals in China...
2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27381481/epilepsy-in-cerebrovascular-diseases-review-of-experimental-and-clinical-data-with-meta-analysis-of-risk-factors
#12
REVIEW
Edoardo Ferlazzo, Sara Gasparini, Ettore Beghi, Chiara Sueri, Emilio Russo, Antonio Leo, Angelo Labate, Antonio Gambardella, Vincenzo Belcastro, Pasquale Striano, Maurizio Paciaroni, Laura Rosa Pisani, Umberto Aguglia
OBJECTIVE: Seizures may occur in close temporal association with a stroke or after a variable interval. Moreover, epilepsy is often encountered in patients with leukoaraiosis. Although early post-stroke seizures have been studied extensively, less attention has been paid to post-stroke epilepsy (PSE) and to epilepsy associated with leukoaraiosis (EAL). The aim of this paper is to review data concerning pathophysiology, prognosis, and treatment of PSE and EAL. METHODS: We performed an extensive literature search to identify experimental and clinical articles on PSE and EAL...
August 2016: Epilepsia
https://www.readbyqxmd.com/read/27330453/2014-epilepsy-benchmarks-area-iv-limit-or-prevent-adverse-consequence-of-seizures-and-their-treatment-across-the-lifespan
#13
Alica M Goldman, W Curt LaFrance, Tim Benke, Miya Asato, Dan Drane, Alison Pack, Tanvir Syed, Robert Doss, Samden Lhatoo, Brandy Fureman, Ray Dingledine
No abstract text is available yet for this article.
May 2016: Epilepsy Currents
https://www.readbyqxmd.com/read/27330451/2014-epilepsy-benchmarks-area-ii-prevent-epilepsy-and-its-progression
#14
Aristea S Galanopoulou, Michael Wong, Devin Binder, Adam L Hartman, Elizabeth M Powell, Avtar Roopra, Richard Staba, Annamaria Vezzani, Brandy Fureman, Ray Dingledine
No abstract text is available yet for this article.
May 2016: Epilepsy Currents
https://www.readbyqxmd.com/read/27330450/2014-epilepsy-benchmarks-area-i-understanding-the-causes-of-the-epilepsies-and-epilepsy-related-neurologic-psychiatric-and-somatic-conditions
#15
Rochelle Caplan, Heather Mefford, Madison Berl, Bernard Chang, Jack Lin, Andrey Mazarati, Brandy Fureman, Ray Dingledine
No abstract text is available yet for this article.
May 2016: Epilepsy Currents
https://www.readbyqxmd.com/read/27311906/tai-chi-for-stroke-rehabilitation-protocol-for-a-systematic-review
#16
Yong Zhang, Shanshan Wang, Pei Chen, Xiaoshu Zhu, Zongheng Li
INTRODUCTION: Stroke is a major cause of death and disability, and imposes a huge burden and significant workload for patients, their families and society. As a special form of physical activity, Tai Chi is may be useful for stroke rehabilitation. The objective of this review is to systematically evaluate the efficacy and safety of Tai Chi for rehabilitation in stroke patients. METHODS AND ANALYSIS: We will conduct a systematic search of the following electronic databases from their inception to 31 October 2015: MEDLINE, EMBASE, the Cochrane Library, the Chinese BioMedical Literature Database (CBM), the Chinese National Knowledge Infrastructure (CNKI), the Chinese Science and Technology Periodical Database (VIP), Wanfang and the Chinese Dissertation Database...
2016: BMJ Open
https://www.readbyqxmd.com/read/27288805/the-pan-american-federation-of-neurological-societies-pafns-a-new-regional-organization
#17
EDITORIAL
Marco T Medina, Gustavo C Román
The Pan-American Federation of Neurological Societies (PAFNS) was created on 15 November 2011 during the 20th World Congress of Neurology in Marrakech by virtue of the "Declaration of Morocco" signed by the WFN Latin American delegates and ratified on 5 March 2012 by delegates attending the 13th Pan-American Congress of Neurology in La Paz, Bolivia. On 20 March 2013 delegates attending the 65th Annual Meeting of the American Academy of Neurology in San Diego, California, USA, gave formal approval to the PAFNS Constitution...
July 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27206707/-specialized-neurological-neurosurgical-intensive-care-medicine
#18
J B Kuramatsu, H B Huttner, S Schwab
In Germany dedicated neurological-neurosurgical critical care (NCC) is the fastest growing specialty and one of the five big disciplines integrated within the German critical care society (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin; DIVI). High-quality investigations based on resilient evidence have underlined the need for technical advances, timely optimization of therapeutic procedures, and multidisciplinary team-work to treat those critically ill patients. This evolution has repeatedly raised questions, whether NCC-units should be run independently or better be incorporated within multidisciplinary critical care units, whether treatment variations exist that impact clinical outcome, and whether nowadays NCC-units can operate cost-efficiently? Stroke is the most frequent disease entity treated on NCC-units, one of the most common causes of death in Germany leading to a great socio-economic burden due to long-term disabled patients...
June 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27203139/body-habitus-serum-albumin-and-the-outcomes-after-craniotomy-for-tumor-a-national-surgical-quality-improvement-program-analysis
#19
Hormuzdiyar H Dasenbrock, Kevin X Liu, Vamsidhar Chavakula, Christopher A Devine, William B Gormley, Elizabeth B Claus, Timothy R Smith, Ian F Dunn
OBJECTIVE Although there is a growing body of research highlighting the negative impact of obesity and malnutrition on surgical outcomes, few studies have evaluated these parameters in patients undergoing intracranial surgery. The goal of this study was to use a national registry to evaluate the association of body mass index (BMI) and hypoalbuminemia with 30-day outcomes after craniotomy for tumor. METHODS Adult patients who underwent craniotomy for tumor were extracted from the prospective National Surgical Quality Improvement Program registry...
May 20, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27165953/determinants-and-outcomes-of-stroke-following-percutaneous-coronary-intervention-by-indication
#20
Phyo Kyaw Myint, Chun Shing Kwok, Christine Roffe, Evangelos Kontopantelis, Azfar Zaman, Colin Berry, Peter F Ludman, Mark A de Belder, Mamas A Mamas
BACKGROUND AND PURPOSE: Stroke after percutaneous coronary intervention (PCI) is a serious complication, but its determinants and outcomes after PCI in different clinical settings are poorly documented. METHODS: The British Cardiovascular Intervention Society (BCIS) database was used to study 560 439 patients who underwent PCI in England and Wales between 2006 and 2013. We examined procedural-type specific determinants of ischemic and hemorrhagic stroke and the likelihood of subsequent 30-day mortality and in-hospital major adverse cardiovascular events (a composite of in-hospital mortality, myocardial infarction or reinfarction, and repeat revascularization)...
June 2016: Stroke; a Journal of Cerebral Circulation
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