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https://www.readbyqxmd.com/read/29554232/outcomes-after-coronary-artery-bypass-grafting-in-patients-with-myocardial-infarction-cardiogenic-shock-and-unresponsive-neurological-state-analysis-of-the-society-of-thoracic-surgeons-database
#1
Morgan L Cox, Brian C Gulack, Dylan P Thibault, Xia He, Matthew L Williams, Vinod H Thourani, Jeffery P Jacobs, J Matthew Brennan, Mani A Daneshmand, Deepak Acharya
OBJECTIVES: Previous studies have demonstrated a 20% mortality rate among patients undergoing isolated coronary artery bypass grafting (CABG) for cardiogenic shock. However, outcomes following CABG for cardiogenic shock in patients who are neurologically unresponsive preoperatively are unknown. METHODS: Utilizing the Society of Thoracic Surgeons Adult Cardiac Surgery Database between July 2011 and December 2013, patients undergoing urgent or emergent CABG within 7 days of an acute myocardial infarction complicated by cardiogenic shock were identified...
March 14, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29545765/clinical-characteristics-and-etiology-of-bilateral-vestibular-loss-in-a-cohort-from-central-illinois
#2
Jorge C Kattah
Background: Previous series of bilateral vestibular loss (BVL) identified numerous etiologies, but surprisingly, a cause in a significant number of cases remains unknown. In an effort to understand possible etiology and management strategies, a global effort is currently in progress. Here, I contribute my 10-year experience with both acute and chronic BVL during the 2007-2017 decade. Methods: This is a retrospective review of the charts and EMR of patients diagnosed with BVL in the last 10 years...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29526058/korean-clinical-practice-guidelines-for-aneurysmal-subarachnoid-hemorrhage
#3
REVIEW
Won-Sang Cho, Jeong Eun Kim, Sukh Que Park, Jun Kyeung Ko, Dae-Won Kim, Jung Cheol Park, Je Young Yeon, Seung Young Chung, Joonho Chung, Sung-Pil Joo, Gyojun Hwang, Deog Young Kim, Won Hyuk Chang, Kyu-Sun Choi, Sung Ho Lee, Seung Hun Sheen, Hyun-Seung Kang, Byung Moon Kim, Hee-Joon Bae, Chang Wan Oh, Hyeon Seon Park
Despite advancements in treating ruptured cerebral aneurysms, an aneurysmal subarachnoid hemorrhage (aSAH) is still a grave cerebrovascular disease associated with a high rate of morbidity and mortality. Based on the literature published to date, worldwide academic and governmental committees have developed clinical practice guidelines (CPGs) to propose standards for disease management in order to achieve the best treatment outcomes for aSAHs. In 2013, the Korean Society of Cerebrovascular Surgeons issued a Korean version of the CPGs for aSAHs...
March 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29484397/adenoviruses-mediated-rna-interference-targeting-cytosolic-phospholipase-a2%C3%AE-attenuates-focal-ischemic-brain-damage-in-mice
#4
Huijun Wu, Hui Liu, Fengtong Zuo, Lihua Zhang
Cerebral ischemia injury is a clinical, frequently occurring disease, which causes a heavy burden on society and families. It has been demonstrated that cytosolic phospholipase A2α (cPLA2α) is significant in neurological injury caused by ischemic brain injury, and inhibition of cPLA2α may reduce stroke injury. In the present study, the role of cPLA2α was investigated in a mouse model of middle cerebral artery occlusion and/or reperfusion (MCAO/R) using an effective cPLA2α inhibitor and adenoviruses‑mediated RNA interference...
February 15, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29482877/the-impact-of-race-on-outcomes-after-carotid-endarterectomy-in-the-united-states
#5
Alexander B Pothof, Peter A Soden, Sarah E Deery, Thomas F X O'Donnell, Grace J Wang, Kakra Hughes, Gert J de Borst, Marc L Schermerhorn
OBJECTIVE: Black patients undergoing carotid endarterectomy (CEA) in the United States are more often symptomatic at presentation and have more comorbidities compared with white patients. However, the impact of race on outcomes after CEA is largely unknown. METHODS: We identified CEA patients in the Vascular Quality Initiative registry (2012-2017) and compared them by race (black vs white). All other nonwhite races (891 [1.4%]) and Hispanics (2222 [3.4%]) were excluded...
February 23, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29478797/multisociety-consensus-quality-improvement-revised-consensus-statement-for-endovascular-therapy-of-acute-ischemic-stroke-from-the-american-association-of-neurological-surgeons-aans-american-society-of-neuroradiology-asnr-cardiovascular-and-interventional-radiology
#6
https://www.readbyqxmd.com/read/29467306/gait-analysis-in-psp-and-nph-dual-task-conditions-make-the-difference
#7
Charlotte Selge, Florian Schoeberl, Andreas Zwergal, Georg Nuebling, Thomas Brandt, Marianne Dieterich, Roman Schniepp, Klaus Jahn
OBJECTIVE: To test whether quantitative gait analysis of gait under single- and dual-task conditions can be used for a differential diagnosis of progressive supranuclear palsy (PSP) and idiopathic normal-pressure hydrocephalus (iNPH). METHODS: In this cross-sectional study, temporal and spatial gait parameters were analyzed in 38 patients with PSP (Neurological Disorders and Stroke and Society for Progressive Supranuclear Palsy diagnostic criteria), 27 patients with iNPH (international iNPH guidelines), and 38 healthy controls...
February 21, 2018: Neurology
https://www.readbyqxmd.com/read/29467072/social-gradients-in-myocardial-infarction-and-stroke-diagnoses-in-emergency-medicine
#8
Christoph Hanefeld, Alexander Haschemi, Thomas Lampert, Hans J Trampisch, Andreas Mügge, Janine Miebach, Cordula Kloppe, Renate Klaaßen-Mielke
BACKGROUND: Persons of lower socio-economic status are at higher risk of disease, especially with respect to severe and chronic illnesses. To date, there have not been any studies with large case numbers regarding acute medical emergencies in this population. METHODS: In a retrospective study, data were obtained on all cases treated by emergency physicians in Bochum, Germany, in 2014/2015, including the diagnoses that were made by the emergency physicians. There were a total of 16 767 cases...
January 26, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29454607/italian-wikipedia-and-epilepsy-an-infodemiological-study-of-online-information-seeking-behavior
#9
Francesco Brigo, Simona Lattanzi, Giorgia Giussani, Laura Tassi, Nicola Pietrafusa, Carlo Andrea Galimberti, Raffaele Nardone, Nicola Luigi Bragazzi, Oriano Mecarelli
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related to epilepsy and its treatment. Using Pageviews Analysis, we assessed the total and mean monthly views of articles from the Italian Wikipedia devoted to epilepsy, epileptic syndromes, seizure type, and antiepileptic drugs (AEDs) from January 1, 2015 to October 31, 2017...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29395420/patient-characteristics-and-in-hospital-outcomes-of-emergency-carotid-endarterectomy-and-carotid-stenting-after-stroke-in-evolution
#10
Christoph Knappich, Andreas Kuehnl, Pavlos Tsantilas, Sofie Schmid, Thorben Breitkreuz, Michael Kallmayer, Alexander Zimmermann, Hans-Henning Eckstein
OBJECTIVE: The objective of this study was to describe characteristics and in-hospital outcomes of patients treated with carotid endarterectomy (CEA) and carotid artery stenting (CAS) for stroke in evolution (SIE) under routine conditions in Germany. METHODS: This secondary data analysis is based on the German statutory quality assurance database for carotid revascularization procedures. Patients with SIE who had undergone CEA or CAS were included. The primary outcome was any new stroke or all-cause death until hospital discharge...
January 27, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29370183/oral-anticoagulant-re-initiation-following-intracerebral-hemorrhage-in-non-valvular-atrial-fibrillation-global-survey-of-the-practices-of-neurologists-neurosurgeons-and-thrombosis-experts
#11
Yan Xu, Ashkan Shoamanesh, Sam Schulman, Dar Dowlatshahi, Rustam Al-Shahi Salman, Ioana Doina Moldovan, Philip Stephen Wells, Fahad AlKherayf
BACKGROUND: While oral anticoagulants (OACs) are highly effective for ischemic stroke prevention in atrial fibrillation, intracerebral hemorrhage (ICH) remains the most feared complication of OAC. Clinical controversy remains regarding OAC resumption and its timing for ICH survivors with atrial fibrillation because the balance between risks and benefits has not been investigated in randomized trials. AIMS/HYPOTHESIS: To survey the practice of stroke neurologists, thrombosis experts and neurosurgeons on OAC re-initiation following OAC-associated ICH...
2018: PloS One
https://www.readbyqxmd.com/read/29363358/analysis-of-national-institutes-of-health-funding-in-hand-surgery
#12
Jason Silvestre, Qing Z Ruan, Benjamin Chang
BACKGROUND: Federal research dollars help investigators develop biomedical therapies for human diseases. Currently, the state of funding in hand surgery is poorly understood. This study defines the portfolio of National Institutes of Health (NIH) grants awarded in hand surgery. METHODS: This was a cross-sectional study of hand surgeons in the US. Faculty members of accredited hand surgery fellowships and/or members of the American Society for Surgery of the Hand were queried in the NIH RePORT database for awards obtained during 2005-2015...
January 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29360254/intravenous-thrombolysis-for-acute-ischaemic-stroke-in-patients-on-direct-oral-anticoagulants
#13
E Touzé, Y Gruel, I Gouin-Thibault, E De Maistre, S Susen, P Sie, L Derex
BACKGROUND AND PURPOSE: Whereas intravenous thrombolysis (IVT) is allowed for acute ischaemic stroke in patients on vitamin K antagonists with international normalized ratio ≤1.7, there are no similar recommendations for patients on direct oral anticoagulants (DOACs), notably due to the lack of coagulation tests to assess the therapeutic effects. Although the literature is scarce, consisting of small case series and retrospective studies, considering the frequency of this situation the French Vascular Neurology Society and the French Study Group on Haemostasis and Thrombosis have worked on a joint position paper to provide a practical position regarding the emergency management of ischaemic stroke in patients on DOACs...
May 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29245245/therapeutic-effect-of-chinese-herbal-medicines-for-post-stroke-recovery-a-traditional-and-network-meta-analysis
#14
Shi-You Han, Zhi-You Hong, Yu-Hua Xie, Yong Zhao, Xiao Xu
BACKGROUND: Stroke is a condition with high morbidity and mortality, and 75% of stroke survivors lose their ability to work. Stroke is a burden to the family and society. The purpose of this study was to evaluate the effectiveness of Chinese herbal patent medicines in the treatment of patients after the acute phase of a stroke. METHODS: We searched the following databases through August 2016: PubMed, Embase, Cochrane library, China Knowledge Resource Integrated Database (CNKI), China Science Periodical Database (CSPD), and China Biology Medicine disc (CBMdisc) for studies that evaluated Chinese herbal patent medicines for post stroke recovery...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29186717/joint-7th-annual-scientific-session-of-the-stroke-prevention-and-control-society-and-chinese-preventive-medicine-association-spcs-cpma-and-6th-international-conference-on-neurology-and-epidemiology-icne-xiamen-china-december-1-3-2017-a-selection-of-abstracts
#15
https://www.readbyqxmd.com/read/29181655/the-organisation-of-the-acute-ischemic-stroke-management-key-notes-of-the-italian-neurological-society-and-of-the-italian-stroke-organization
#16
E Agostoni, A Carolei, G Micieli, L Provinciali, D Toni, Simone Vidale
The main aim of acute ischemic stroke treatment is the as much possible prompt, safe and effective arterial recanalisation, in order to restore reperfusion into the ischemic brain area. The procedures obtaining this result are rapidly evolving and in the last years, we observed new evidences that affirmed the therapeutical benefit of the concomitant treatment using endovenous thrombolysis and mechanical thrombectomy in selected patients with ischemic stroke. However, all treatments are time-sensitive and the main limitation for their application is represented by the time...
November 27, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29163069/notes-on-the-recent-history-of-neuroscience-in-africa
#17
REVIEW
Vivienne A Russell
Neuroscience began with neuroanatomy and neurosurgery in Egypt more than 5000 years ago. Knowledge grew over time and specialized neurosurgery centers were established in north Africa in the eleventh century. However, it was not until the twentieth century that neuroscience research became established in sub-Saharan Africa. In most African countries, clinical research focused on understanding the rationale and improving treatment of epilepsy, infections, nutritional neuropathies, stroke and tumors. Significant advances were made...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29117605/-new-oral-anticoagulants-noac-in-stroke-treatment
#18
Clemens Küpper, Lars Kellert, Steffen Tiedt, Frank Arne Wollenweber
Since 2011, new oral anticoagulants (NOAC) can be prescribed for prevention of cardio-embolic ischemic strokes in addition to vitamin K antagonists. NOAC are indicated in patients with non-valvular atrial fibrillation. Although its use is a matter of debate in Germany, the neurological and cardiological societies recommend the use of NOAC over and above vitamin K antagonists due to a better benefit-to-risk ratio attributed to it, especially because of the lower risk of intracranial hemorrhage in NOAC use. A specific antidote is commercially available for the direct thrombin inhibitor dabigatran only...
February 2018: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29105074/common-data-elements-for-preclinical-epilepsy-research-standards-for-data-collection-and-reporting-a-task3-report-of-the-aes-ilae-translational-task-force-of-the-ilae
#19
Lauren C Harte-Hargrove, Jacqueline A French, Asla Pitkänen, Aristea S Galanopoulou, Vicky Whittemore, Helen E Scharfman
The major objective of preclinical translational epilepsy research is to advance laboratory findings toward clinical application by testing potential treatments in animal models of seizures and epilepsy. Recently there has been a focus on the failure of preclinical discoveries to translate reliably, or even to be reproduced in different laboratories. One potential cause is a lack of standardization in preclinical data collection. The resulting difficulties in comparing data across studies have led to high cost and missed opportunity, which in turn impede clinical trials and advances in medical care...
November 2017: Epilepsia
https://www.readbyqxmd.com/read/29059659/-post-stroke-spasticity-management-including-a-chosen-physiotherapeutic-methods-and-improvements-in-motor-control-review-of-the-current-scientific-evidence
#20
Robert Dymarek, Kuba Ptaszkowski, Lucyna Słupska, Małgorzata Paprocka-Borowicz, Jakub Taradaj, Tomasz Halski, Joanna Rosińczuk
Cerebrovascular diseases based on stroke etiology concern millions of people worldwide, and annual rates of disease are still increasing. In the era of an aging society and suffering from a number of risk factors, in particular those modifiable, strokes and muscles' spastic paresis, subsequently resulting in damage of upper motor neuron structures will become a serious problem for the entire health care system. Effective management and physiotherapy treatment for post-stroke spasticity persisted, both in the acute and chronic, is still a significant medical problem in the interdisciplinary aspect...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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