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Limitations of studies with elderly

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https://www.readbyqxmd.com/read/27904100/usefulness-of-oral-care-related-information-provision-at-drugstores-to-prevent-pneumonia
#1
Masaru Mizoguchi, Sako Kuwano, Ikuko Suzuki, Masato Shigeyama
 Although the removal of bacteria in the oral cavity is regarded as an important preventive measure against pneumonia, the majority of elderly individuals are rarely provided with oral care-related information. This study examined the usefulness of oral care-related information provision for the elderly by pharmacists working at drugstores. A questionnaire survey was conducted, involving 387 pharmacists working at drugstores and 51 elderly individuals who visited such stores. Oral care-related information had been actively provided by 14...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/27901247/anabolic-steroids-for-rehabilitation-after-hip-fracture-in-older-people
#2
Vaqas Farooqi, Maayken E L van den Berg, Ian D Cameron, Maria Crotty
BACKGROUND: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combination with exercise to improve muscle mass and strength in athletes. They may have similar effects in older people who are recovering from hip fracture. OBJECTIVES: To examine the effects (primarily in terms of functional outcome and adverse events) of anabolic steroids after surgical treatment of hip fracture in older people...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27901246/chemotherapy-for-advanced-non-small-cell-lung-cancer-in-the-elderly-population
#3
Fábio Nasser Santos, Tiago Biachi de Castria, Marcelo Rocha Souza Cruz, Rachel Riera
BACKGROUND: Approximately 50% of patients with newly diagnosed non-small cell lung cancer (NSCLC) are over 70 years of age at diagnosis. Despite this fact, these patients are underrepresented in randomized controlled trials (RCTs). As a consequence, the most appropriate regimens for these patients are controversial, and the role of single-agent or combination therapy is unclear. In this setting, a critical systematic review of RCTs in this group of patients is warranted. OBJECTIVES: To assess the effectiveness and safety of different cytotoxic chemotherapy regimens for previously untreated elderly patients with advanced (stage IIIB and IV) NSCLC...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27896794/efficacy-and-safety-of-ultrasound-guided-placement-of-central-venous-port-systems-via-the-right-internal-jugular-vein-in-elderly-oncologic-patients-our-single-center-experience-and-protocol
#4
Alfonso Canfora, Claudio Mauriello, Antonio Ferronetti, Gianpaolo Marte, Vittorio Di Maio, Guido Ciorra, Maria Grazia Esposito, Maria Elena Giuliano, Giovanni Fregola, Luigi Barra, Salvatore Cuzzovaglia, Vincenzo Bottino, Pietro Maida
BACKGROUND: Ultrasound-guidance has become the routine method for internal jugular vein (IJV) catheterization reducing dramatically failure and complication rates for central venous port (CVP) placement. AIMS: The aim of this study was to determine the safety and efficacy of ultrasound-guided IJV CVP placement in elderly oncologic patients. METHODS: Between January 2013 and December 2015, 101 elderly oncological patients underwent right IJV CVP placement under ultrasound-guidance...
November 28, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27895432/prevalence-of-depression-and-anxiety-in-patients-with-chronic-digestive-system-diseases-a-multicenter-epidemiological-study
#5
An-Zhong Zhang, Qing-Cai Wang, Kun-Ming Huang, Jia-Guo Huang, Chang-Hong Zhou, Fu-Qiang Sun, Su-Wen Wang, Feng-Ting Wu
AIM: To investigate the prevalence of depression and anxiety in patients with chronic digestive system diseases. METHODS: A total of 1736 patients with chronic digestive system diseases were included in this cross-sectional study, including 871 outpatients and 865 in-patients. A self-designed General Information for Patients of the Department of Gastroenterology of General Hospitals questionnaire was used to collect each patient's general information, which included demographic data (including age, sex, marital status, and education) and disease characteristics (including major diseases, disease duration, principal symptoms, chronic pain, sleep disorder, and limited daily activities)...
November 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27894479/-the-benefit-of-telemedicine-for-enabling-elderly-or-disabled-people-to-access-care
#6
Yohann Eudes, Katia Mangeney, Michel Diméo, Stéphane Pierrel, Stavros Sokolakis, Stéphane Carnein
In 2013, a convalescence and care home carried out a telemedicine experiment in order to favour access to care for elderly and/or disabled people. In this context, in accordance with regulations, the team carried out an assessment of the project by studying the added value of this tool, its limits, as well as the initial effects on the residents and the practices of the healthcare professionals.
November 2016: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/27887596/effectiveness-immunogenicity-and-safety-of-23-valent-pneumococcal-polysaccharide-vaccine-revaccinations-in-the-elderly-a-systematic-review
#7
Cornelius Remschmidt, Thomas Harder, Ole Wichmann, Christian Bogdan, Gerhard Falkenhorst
BACKGROUND: In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal disease in the elderly. However, vaccine-induced immunity wanes after a few years, and there are controversies around revaccination with PPSV-23. Here, we systematically assessed the effectiveness and safety of PPSV-23 revaccination. METHOD: We conducted a systematic literature review in MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials from inception to June 2015...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27886569/effects-of-a-right-unilateral-ultrabrief-pulse-electroconvulsive-therapy-course-on-health-related-quality-of-life-in-elderly-depressed-patients
#8
W Vaughn McCall, Sarah H Lisanby, Peter B Rosenquist, Mary Dooley, Mustafa M Husain, Rebecca G Knapp, Georgios Petrides, Matthew V Rudorfer, Robert C Young, Shawn M McClintock, Martina Mueller, Joan Prudic, Robert M Greenberg, Richard D Weiner, Samuel H Bailine, Mary Anne Riley, Laryssa McCloud, Charles H Kellner
INTRODUCTION: Patients with Major Depressive Disorder (MDD) referred for electroconvulsive therapy (ECT) have poorer Health Related Quality of Life (HRQOL), compared with other patients with MDD, but ECT is associated with significant and durable improvement in HRQOL. However, no prior research has focused exclusively on elderly patients with MDD receiving ECT. METHODS: HRQOL data from 240 depressed patients over the age of 60 was measured with the Medical Outcomes Study Short Form 36 (SF-36)...
November 11, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27886067/a-real-time-kinect-signature-based-patient-home-monitoring-system
#9
Gaddi Blumrosen, Yael Miron, Nathan Intrator, Meir Plotnik
Assessment of body kinematics during performance of daily life activities at home plays a significant role in medical condition monitoring of elderly people and patients with neurological disorders. The affordable and non-wearable Microsoft Kinect ("Kinect") system has been recently used to estimate human subject kinematic features. However, the Kinect suffers from a limited range and angular coverage, distortion in skeleton joints' estimations, and erroneous multiplexing of different subjects' estimations to one...
November 23, 2016: Sensors
https://www.readbyqxmd.com/read/27885225/the-physical-signs-of-impending-dehydration-among-elderly-people-in-nursing-homes-the-association-with-axillary-skin-temperature-humidity-intraoral-moisture-content-and-salivary-components
#10
Mayumi Okuyama, Masumi Nishida
PURPOSE: The aim of the present study was to examine the association between impending dehydration among elderly people in nursing homes and physical signs, including the axillary skin temperature, humidity, intraoral moisture content, and salivary components. METHODS: The study included 78 elderly individuals who required long-term care in a nursing home (11 men and 67 women; average age, 86.6±7.3 years). The elderly subjects were classified in two groups according to their serum osmolality levels: those with levels between the upper limit reference value (292 mOsm/kg H2O) and the diagnostic reference value of dehydration (300 mOsm/kg H2O) were classified into the boundary zone group and those with levels of <292 mOsm/kg H2O were classified into the normal range group...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27885107/a-systematic-review-of-clinical-prediction-scores-for-deep-vein-thrombosis
#11
REVIEW
Marina Kafeza, Joseph Shalhoub, Nina Salooja, Lucy Bingham, Konstantina Spagou, Alun H Davies
OBJECTIVE: Diagnosis of deep vein thrombosis remains a challenging problem. Various clinical prediction rules have been developed in order to improve diagnosis and decision making in relation to deep vein thrombosis. The purpose of this review is to summarise the available clinical scores and describe their applicability and limitations. METHODS: A systematic search of PubMed, MEDLINE and EMBASE databases was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance using the keywords: clinical score, clinical prediction rule, risk assessment, clinical probability, pretest probability, diagnostic score and medical Subject Heading terms: 'Venous Thromboembolism/diagnosis' OR 'Venous Thrombosis/diagnosis'...
November 24, 2016: Phlebology
https://www.readbyqxmd.com/read/27878556/venous-anomalies-of-the-axilla-a-single-institution-experience
#12
Viviana Sollazzo, Gaetano Luglio, Emanuela Esposito, Rosa Di Micco, Mariano Cesare Giglio, Roberto Peltrini, Pietro Schettino, Bruno Amato, Giovanni Domenico De Palma, Gennaro Limite
AIM: Surgical treatment is still the cornerstone in the treatment of breast cancer, a very common neoplasia, particularly affecting the female elderly population. Axillary dissection is crucial in the treatment of some tumours, but variations in axillary vessels anatomy are poorly described in standard anatomy and surgical textbook. We aimed to describe anatomical variations in axillary vessels found in our institutional experience. PATIENTS AND METHODS: A prospective 3-year study was conducted in our institution from January 2012 to December 2014...
November 22, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27878555/laparoscopic-distal-pancreatectomy-in-elderly-patients-is-it-safe
#13
Giovanni Aprea, Davide De Rosa, Marco Milone, Aldo Rocca, Tommaso Bianco, Guido Massa, Rita Compagna, Louis Banka Johnson, Alessandro Sanguinetti, Andrea Polistena, Nicola Avenia, Bruno Amato
BACKGROUND: Laparoscopic distal pancreatectomy (LDP) appears to be safe and effective as open distal pancreatectomy (ODP) for benign or borderline malignant lesion. However, studies comparing LDP with ODP in elderly patients are limited. The purpose of this study is to compare the clinical outcomes of these two several approaches in elderly patients. METHODS: A retrospective analysis was carried out by comparing laparoscopic (n = 7) and open (n = 15) distal pancreatectomy in elderly patients performed at the University of Naples "Federico II" and University of Perugia between January 2012 and December 2015...
November 22, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27877027/fatigue-as-a-long-term-risk-factor-for-limitations-in-instrumental-activities-of-daily-living-and-or-mobility-performance-in-older-adults-after-10-years
#14
Sigrid Mueller-Schotte, Nienke Bleijenberg, Yvonne T van der Schouw, Marieke J Schuurmans
OBJECTIVES: Decline in the performance of instrumental activities of daily living (IADL) and mobility may be preceded by symptoms the patient experiences, such as fatigue. The aim of this study is to investigate whether self-reported non-task-specific fatigue is a long-term risk factor for IADL-limitations and/or mobility performance in older adults after 10 years. METHODS: A prospective study from two previously conducted cross-sectional studies with 10-year follow-up was conducted among 285 males and 249 females aged 40-79 years at baseline...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27869535/serum-thyroid-stimulating-hormone-levelsand-frailty-in-the-elderly-the-pro-v-a-study
#15
Nicola Veronese, Sara Watutantrige, Stefania Maggi, Marianna Noale, Brendon Stubbs, Raffaele Antonelli Incalzi, Sabina Zambon, Maria Chiara Corti, Egle Perissinotto, Gaetano Crepaldi, Enzo Manzato, Giuseppe Sergi
High or low thyroid-stimulating hormone (TSH) levels seem to be associated with several negative outcomes in the elderly, but the literature about TSH and frailty is still limited. In this paper, we investigated whether TSH is associated with prevalent and incident frailty in a cohort of older community-dwelling subjects. Among 3,099 initially screened in the Progetto Veneto Anziani Study, 2,571 men and women aged >65 years (for cross-sectional analyses) and 1,732 (longitudinal, mean follow-up period of 4...
November 21, 2016: Rejuvenation Research
https://www.readbyqxmd.com/read/27869298/informant-questionnaire-on-cognitive-decline-in-the-elderly-iqcode-for-the-early-diagnosis-of-dementia-across-a-variety-of-healthcare-settings
#16
REVIEW
Jennifer K Harrison, David J Stott, Rupert McShane, Anna H Noel-Storr, Rhiannon S Swann-Price, Terry J Quinn
BACKGROUND: The Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) is a structured interview based on informant responses that is used to assess for possible dementia. IQCODE has been used for retrospective or contemporaneous assessment of cognitive decline. There is considerable interest in tests that may identify those at future risk of developing dementia. Assessing a population free of dementia for the prospective development of dementia is an approach often used in studies of dementia biomarkers...
November 21, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27866215/impact-of-body-mass-index-on-risk-of-acute-kidney-injury-and-mortality-in-elderly-patients-undergoing-hip-fracture-surgery
#17
A B Pedersen, H Gammelager, J Kahlert, H T Sørensen, C F Christiansen
: The literature is limited regarding risk factors for acute kidney injury (AKI) and mortality in hip fracture patients, although AKI is common in these patients. While obese patients were at increased risk of AKI, underweight patients with and without AKI had elevated mortality for up to 1 year after hip fracture surgery, compared with normal-weight patients. INTRODUCTION: This study aimed to examine risk of postoperative AKI and subsequent mortality, by body mass index (BMI) level, in hip fracture surgery patients aged 65 and over...
November 19, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27865292/katrina-s-legacy-processes-for-patient-disaster-preparation-have-improved-but-important-gaps-remain
#18
Marjorie Icenogle, Sasha Eastburn, Martha Arrieta
BACKGROUND: Ensuring continuity of care for patients with chronic illness, who are elderly or indigent presents unique challenges after disasters; this population has fewer financial resources, is less likely to evacuate, has limited access to recovery resources and is significantly dependent on charitable and government-funded institutions for care. This study expands a previous investigation of the extent to which healthcare providers in coastal Mississippi and Alabama have made changes to facilitate continued care to these populations after disasters...
November 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27861296/are-octogenarians-with-end-stage-renal-disease-candidates-for-renal-transplantation
#19
Kjersti Lønning, Karsten Midtvedt, Torbjørn Leivestad, Anna V Reisæter, Pål-Dag Line, Anders Hartmann, Kristian Heldal
BACKGROUND: Elderly patients are the fastest-growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their 80th year or longer at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation? METHODS: Recipients in their 80th year or longer, transplanted between 1983 and 2015, were included. Data were retrieved from the Norwegian Renal Registry in the end of October 2015. Graft and patient survivals were compared with recipients aged 70 to 79 years at transplantation...
December 2016: Transplantation
https://www.readbyqxmd.com/read/27847793/comparison-of-survival-of-surgical-resection-and-conservative-treatment-in-patients-with-gastric-cancer-aged-80-years-or-older-a-single-center-experience
#20
Chung-Sik Gong, Jeong-Hwan Yook, Sung-Tae Oh, Byung-Sik Kim
PURPOSE: With the increase in the average life expectancy, the elderly population continues to increase rapidly. However, no consensus has been reached on the feasibility for surgical resection due to the high morbidity and mortality rate after surgical treatment in elderly patients caused by aging and underlying diseases. METHODS: This study was performed with patients aged 80 years and older. The subjects were classified into 2 groups as follows: the surgical resection group consisting of 61 patients, and the conservative treatment group consisting of 39 patients suitable for curative resection...
November 2016: Annals of Surgical Treatment and Research
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