Sofia Toniolo, Sijia Zhao, Anna Scholcz, Benazir Amein, Akke Ganse-Dumrath, Amanda J Heslegrave, Sian Thompson, Sanjay Manohar, Henrik Zetterberg, Masud Husain
INTRODUCTION: A major limitation in Alzheimer's disease (AD) research is the lack of the ability to measure cognitive performance at scale-robustly, remotely, and frequently. Currently, there are no established online digital platforms validated against plasma biomarkers of AD. METHODS: We used a novel web-based platform that assessed different cognitive functions in AD patients ( N = 46) and elderly controls ( N = 53) who were also evaluated for plasma biomarkers (amyloid beta 42/40 ratio, phosphorylated tau ([p-tau]181, glial fibrillary acidic protein, neurofilament light chain)...
2024: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring