Yongsheng Ma, Qitai Lin, Wenming Yang, Yang Liu, Yugang Xing, Zhiyuan Ren, Xueding Wang, Raorao Zhou, Gaige Wu, Pengcui Li, Wangping Duan, Xiaoling Zhang, Xiaochun Wei
OBJECTIVES: The current clinical pulse lavage technique for flushing fresh osteochondral allografts (OCAs) to remove immunogenic elements from the subchondral bone is ineffective. This study aimed to identify the optimal method for removing immunogenic elements from OCAs. METHODS: We examined five methods for the physical removal of immunogenic elements from OCAs from the femoral condyle of porcine knees. We distributed the OCAs randomly into the following seven groups: (1) control, (2) saline, (3) ultrasound, (4) vortex vibration (VV), (5) low-pulse lavage (LPL), (6) high-pulse lavage (HPL), and (7) high-speed centrifugation (HSC)...
January 18, 2024: Orthopaedic Surgery