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https://www.readbyqxmd.com/read/28209979/fractionating-impulsivity-neuropsychiatric-implications
#1
REVIEW
Jeffrey W Dalley, Trevor W Robbins
The ability to make decisions and act quickly without hesitation can be advantageous in many settings. However, when persistently expressed, impulsive decisions and actions are considered risky, maladaptive and symptomatic of such diverse brain disorders as attention-deficit hyperactivity disorder, drug addiction and affective disorders. Over the past decade, rapid progress has been made in the identification of discrete neural networks that underlie different forms of impulsivity - from impaired response inhibition and risky decision making to a profound intolerance of delayed rewards...
February 17, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28186338/research-review-language-problems-in-children-with-attention-deficit-hyperactivity-disorder-a-systematic-meta-analytic-review
#2
REVIEW
Hannah Korrel, Kathryn L Mueller, Tim Silk, Vicki Anderson, Emma Sciberras
BACKGROUND: Children with Attention-Deficit Hyperactivity Disorder (ADHD) appear to have a higher risk of language problems compared with typically developing children, although the types of language problems experienced are less clear. This review aims to establish the types of language problems experienced by children with ADHD according to systematically reviewed literature and determine the empirical evidence for language problems in children with ADHD compared with non-ADHD controls...
February 10, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28184164/assessment-and-monitoring-of-treatment-response-in-adult-adhd-patients-current-perspectives
#3
REVIEW
J Russell Ramsay
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental syndrome that emerges in childhood or early adolescence and persists into adulthood for a majority of individuals. There are many other adults with ADHD who may not seek out evaluation and treatment until adulthood, having been able to "get by" before struggling with inattention, hyperactivity, and/or impulsivity in adulthood, in addition to facing the associated features of disorganization, poor time management, and procrastination among many others...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28180053/isolated-spontaneous-midbrain-hemorrhage-in-a-14-year-old-boy
#4
Kim-Long R Nguyen, Hyunyoung Kim, Laszlo Nagy
Isolated spontaneous midbrain hemorrhages are rare because they are usually secondary to hemorrhages from inferior structures such as the pons and cerebellum, or superior structures such as the thalamus and putamen. While the etiologies are largely unidentified, the most common ones are vascular malformations and bleeding diathesis with hypertension being relatively uncommon. We report midbrain hemorrhage in a 14-year-old boy with a long-standing history of frequent migraine headaches and attention deficit/hyperactivity disorder (ADHD)...
January 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28168597/the-role-of-nutritional-supplements-in-the-treatment-of-adhd-what-the-evidence-says
#5
REVIEW
Klaus W Lange, Joachim Hauser, Katharina M Lange, Ewelina Makulska-Gertruda, Yukiko Nakamura, Andreas Reissmann, Yuko Sakaue, Tomoyuki Takano, Yoshihiro Takeuchi
Attention-deficit hyperactivity disorder (ADHD) is a common behavioral disorder in children and adolescents and may persist into adulthood. Insufficient nutritional supply of long-chain polyunsaturated fatty acids (LC-PUFAs) and other components including various minerals has been suggested to play a role in the development of ADHD symptoms. This review presents the evidence regarding the role of nutritional PUFA, zinc, iron, and magnesium supplements in the treatment of ADHD with a focus on the critical evaluation of the relevant literature published from 2014 to April 2016...
February 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28164727/psychometric-properties-of-the-vanderbilt-adhd-diagnostic-rating-scale-completed-by-juvenile-corrections-staff
#6
Regina Bussing, Joseph C Gagnon, Cynthia W Garvan, Cecelia Ribuffo-Duggan, David Houchins
OBJECTIVE: This research tests the psychometric performance of the Vanderbilt ADHD Diagnostic Teacher Rating Scale (VADTRS) completed by juvenile corrections (JC) staff. METHOD: With institutional review board (IRB) approval and appropriate consents/assents, data were collected from case managers ( n = 18), teachers ( n = 9), youth ( n = 261), and an administrative database. Separate psychometric analyses were conducted for case managers and teachers. RESULTS: For both respondent groups, 2-week retest reliability and internal consistency were high for all four VADTRS subscales, and confirmatory factor analysis suggested fit with previously reported VADTRS subscale structure...
February 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28164277/event-related-potential-measures-of-executive-functioning-from-preschool-to-adolescence
#7
REVIEW
Michelle Downes, Joe Bathelt, Michelle De Haan
Executive functions are a collection of cognitive abilities necessary for behavioural control and regulation, and are important for school success. Executive deficits are common across acquired and developmental disorders in childhood and beyond. This review aims to summarize how studies using event-related potential (ERP) can provide insight into mechanisms underpinning how executive functions develop in children from preschool to adolescence. We specifically focus on ERP components that are considered to be well-established markers of executive functioning, including the ability to resist distraction (inhibition, N200), hold scenes in mind (visuospatial working memory, contralateral delay activity), attend to specific stimuli (information processing, P300), follow rules (response monitoring, error-related negativity [ERN], and error-related positivity [Pe]), and adjust to feedback (outcome monitoring, feedback-related negativity)...
February 6, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28159610/brain-imaging-genetics-in-adhd-and-beyond-mapping-pathways-from-gene-to-disorder-at-different-levels-of-complexity
#8
REVIEW
Marieke Klein, Marten Onnink, Marjolein van Donkelaar, Thomas Wolfers, Benjamin Harich, Yan Shi, Janneke Dammers, Alejandro Arias-Va Squez, Martine Hoogman, Barbara Franke
Attention-deficit/hyperactivity disorder (ADHD) is a common and often persistent neurodevelopmental disorder. Beyond gene-finding, neurobiological parameters, such as brain structure, connectivity, and function, have been used to link genetic variation to ADHD symptomatology. We performed a systematic review of brain imaging genetics studies involving 62 ADHD candidate genes in childhood and adult ADHD cohorts. Fifty-one eligible research articles described studies of 13 ADHD candidate genes. Almost exclusively, single genetic variants were studied, mostly focussing on dopamine-related genes...
January 31, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28141707/bullying-and-adhd-which-came-first-and-does-it-matter
#9
Robert Keder, Robert Sege, Peter C Raffalli, Marilyn Augustyn
Aiden, a 13-year-old boy in the sixth grade who is relatively new to your practice, is seen for follow-up after his routine physical last month when you noted concerns for possible attention-deficit hyperactivity disorder (ADHD) and gave the family Vanderbilt Scales to complete. Aiden has a family history of ADHD, specific learning disabilities, and mood disorder.His mother reports that she is concerned about how Aiden is doing at school; his teachers are complaining that he is not doing his work, and she is worried that he may be kept back in school...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28137522/herbal-medicines-in-children-with-attention-deficit-hyperactivity-disorder-adhd-a-systematic-review
#10
REVIEW
Dennis Anheyer, Romy Lauche, Dania Schumann, Gustav Dobos, Holger Cramer
OBJECTIVE: The purpose of this review is to identify evidence in herbal therapy in the treatment of ADHD concerning effectiveness and drug tolerability. METHOD: For this Medline/PubMed, Scopus and the Cochrane Central Register of Controlled Trials (Central) were searched from their inception to 15 July 2016. Only randomized controlled trails (RCT) with children (0-18years) suffering from ADHD were included in this review. RESULTS: Nine RCTs with 464 patients comparing herbal pharmaceuticals to placebo or active control were included...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28130762/new-formulations-of-methylphenidate-for-the-treatment-of-attention-deficit-hyperactivity-disorder-pharmacokinetics-efficacy-and-tolerability
#11
REVIEW
Samuele Cortese, Giulia D'Acunto, Eric Konofal, Gabriele Masi, Benedetto Vitiello
Psychostimulants are the recommended first-line pharmacological treatment for attention-deficit/hyperactivity disorder (ADHD). Methylphenidate is one of the most commonly used psychostimulants worldwide. Given that immediate-release and/or tablet/capsule formulations may decrease adherence to methylphenidate treatment, several drug companies have been developing novel long-acting and/or liquid/chewable formulations that may improve adherence as well as (for long-acting formulations) reduce abuse potential, decrease stigma associated with multiple administrations per day, and decrease the potential for adverse effects related to dosage peak...
February 2017: CNS Drugs
https://www.readbyqxmd.com/read/28128989/social-functioning-in-children-with-or-at-risk-for-attention-deficit-hyperactivity-disorder-a-meta-analytic-review
#12
Rosmary Ros, Paulo A Graziano
Considerable work has demonstrated significant impairment in social functioning for children with attention deficit/hyperactivity disorder (ADHD). The social functioning profiles of children with ADHD are marked by impairments across diverse domains as they tend to experience greater rates of peer rejection, have lower levels of social skills, and have impaired social cognitions. The purpose of this study was to (a) quantitatively examine the association between ADHD and deficits across several domains of social functioning (peer functioning, social skills, social information processing), (b) examine differences in the magnitude of such associations, and (c) examine the effect of potential moderators...
January 27, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28124223/is-adhd-a-valid-diagnosis-in-older-adults
#13
REVIEW
Craig B H Surman, David W Goodman
ADHD is a neurodevelopmental syndrome that often persists into adulthood. It is possible that different criteria are necessary for older adults than younger adults: the manifestations of ADHD could change with age; other conditions with onset in later life share presenting symptoms with ADHD; different contextual challenges and patterns of compensatory support may exist. For these reasons, we reviewed evidence for the validity of DSM ADHD criteria in adulthood for individuals over the age of 50. Specifically, we evaluated evidence that the DSM criteria for ADHD identify a valid syndrome in older adults based on clinical presentation, laboratory or testing findings, absence of alternate diagnosis to explain symptoms, course of the syndrome, or familial presence of the condition...
January 25, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28123654/the-relationship-between-epilepsy-sleep-disorders-and-attention-deficit-hyperactivity-disorder-adhd-in-children-a-review-of-the-literature
#14
REVIEW
Felipe Kalil Neto, Renan Noschang, Magda Lahorgue Nunes
OBJECTIVE: To analyze the relationship between epilepsy, sleep disorders, and attention deficit hyperactivity disorder (ADHD). BIBLIOGRAPHIC SEARCH: A literature search of the PubMed database was performed using the following key words: epilepsy, sleep, and ADHD. In total, 91 articles were located in PubMed, 34 were selected for abstract reading and twelve articles were reviewed, in which the main objectives were examine the relationship between epilepsy, sleep and ADHD from several perspectives, including epidemiology, effect of comorbidities on academic performance and the factors leading to diagnostic difficulties among these three disorders...
July 2016: Sleep Science
https://www.readbyqxmd.com/read/28121994/diet-and-adhd-reviewing-the-evidence-a-systematic-review-of-meta-analyses-of-double-blind-placebo-controlled-trials-evaluating-the-efficacy-of-diet-interventions-on-the-behavior-of-children-with-adhd
#15
Lidy M Pelsser, Klaas Frankena, Jan Toorman, Rob Rodrigues Pereira
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is a debilitating mental health problem hampering the child's development. The underlying causes include both genetic and environmental factors and may differ between individuals. The efficacy of diet treatments in ADHD was recently evaluated in three reviews, reporting divergent and confusing conclusions based on heterogeneous studies and subjects. To address this inconsistency we conducted a systematic review of meta-analyses of double-blind placebo-controlled trials evaluating the effect of diet interventions (elimination and supplementation) on ADHD...
2017: PloS One
https://www.readbyqxmd.com/read/28115272/palmitoylation-mechanisms-in-dopamine-transporter-regulation
#16
REVIEW
Danielle E Rastedt, Roxanne A Vaughan, James D Foster
The neurotransmitter dopamine (DA) plays a key role in several biological processes including reward, mood, motor activity and attention. Synaptic DA homeostasis is controlled by the dopamine transporter (DAT) which transports extracellular DA into the presynaptic neuron after release and regulates its availability to receptors. Many neurological disorders such as schizophrenia, bipolar disorder, Parkinson disease and attention-deficit hyperactivity disorder are associated with imbalances in DA homeostasis that may be related to DAT dysfunction...
January 20, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28112025/validation-of-the-use-of-electronic-health-records-for-classification-of-adhd-status
#17
Siobhan M Gruschow, Benjamin E Yerys, Thomas J Power, Dennis R Durbin, Allison E Curry
OBJECTIVE: To validate an electronic health record (EHR)-based algorithm to classify ADHD status of pediatric patients. METHOD: As part of an applied study, we identified all primary care patients of The Children's Hospital of Philadelphia [CHOP] health care network who were born 1987-1995 and residents of New Jersey. Patients were classified with ADHD if their EHR indicated an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis code of "314...
October 1, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28111269/association-of-atopic-diseases-and-attention-deficit-hyperactivity-disorder-a-systematic-review-and-meta-analyses
#18
REVIEW
Jurjen van der Schans, Rukiye Çiçek, Tjalling W de Vries, Eelko Hak, Pieter J Hoekstra
Over the last decades, the hypothesis has been raised that an atopic response could lead to the development of attention-deficit/hyperactivity disorder (ADHD). This study systematically reviews the observational cross-sectional and longitudinal studies that assessed the association between atopic disorders including asthma, atopic eczema, allergic rhinitis, and ADHD in children and adolescents. For longitudinal studies, a weighted Mantel-Haenszel odds ratio of these associations was estimated. The majority of cross-sectional and longitudinal studies reported a statistically significant positive association...
January 20, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28110366/atomoxetine-treatment-for-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-adhd-a-comprehensive-meta-analysis-of-outcomes-on-parent-rated-core-symptomatology
#19
REVIEW
Jessica L Gayleard, Matthew P Mychailyszyn
Attention-Deficit/Hyperactivity Disorder (ADHD) impacts a significant number of children and adolescents and often leads to deleterious functional impairment. Psychostimulant medication has historically been the first line of pharmacological intervention, though recent years have seen greater attention paid to non-stimulant alternatives. The objective of the present study was to conduct the most comprehensive meta-analysis to date evaluating the efficacy of atomoxetine in reducing core symptomatology of ADHD according to parent report...
January 21, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28106934/neuroimaging-the-neural-correlates-of-increased-risk-for-substance-use-disorders-in-attention-deficit-hyperactivity-disorder-a-systematic-review
#20
Vitria Adisetiyo, Kevin M Gray
BACKGROUND/OBJECTIVES: Children with attention-deficit/hyperactivity disorder (ADHD) are nearly three times more likely to develop substance use disorders (SUD) than their typically developing peers. Our objective was to review the existing neuroimaging research on high-risk ADHD (ie, ADHD with disruptive behavior disorders, familial SUD and/or early substance use), focusing on impulsivity as one possible mechanism underlying SUD risk. METHODS: A PubMed literature search was conducted using combinations of the keywords "ADHD," "substance use," "substance use disorder," "SUD," "addiction," "dependence," "abuse," "risk," "brain" "MRI," "imaging" and "neuroimaging...
January 20, 2017: American Journal on Addictions
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