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https://www.readbyqxmd.com/read/28729328/comparative-safety-of-antiepileptic-drugs-for-neurological-development-in-children-exposed-during-pregnancy-and-breast-feeding-a-systematic-review-and-network-meta-analysis
#1
Areti Angeliki Veroniki, Patricia Rios, Elise Cogo, Sharon E Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R Hemmelgarn, Fatemeh Yazdi, Jennifer D'Souza, Heather MacDonald, Andrea C Tricco
OBJECTIVES: Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children exposed in utero or during breast feeding. DESIGN AND SETTING: Systematic review and Bayesian random-effects network meta-analysis (NMA). MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched until 27 April 2017. Screening, data abstraction and quality appraisal were completed in duplicate by independent reviewers. PARTICIPANTS: 29 cohort studies including 5100 infants/children...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28726231/-emotional-facial-recognition-difficulties-as-primary-deficit-in-children-with-attention-deficit-hyperactivity-disorder-a-systematic-review
#2
D Rodrigo-Ruiz, J C Perez-Gonzalez, J Cejudo
INTRODUCTION: It has recently been warned that children with attention deficit hyperactivity disorder (ADHD) show a deficit in emotional competence and emotional intelligence, specifically in their ability to emotional recognition. PATIENTS AND METHODS: A systematic review of the scientific literature in reference to the emotional recognition of facial expressions in children with ADHD is presented in order to establish or rule the existence of emotional deficits as primary dysfunction in this disorder and, where appropriate, the effect size of the differences against normal development or neurotypical children...
August 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28724403/the-association-between-attention-deficit-hyperactivity-disorder-and-internet-addiction-a-systematic-review-and-meta-analysis
#3
Bing-Qian Wang, Nan-Qi Yao, Xiang Zhou, Jian Liu, Zheng-Tao Lv
BACKGROUND: This study aimed to analyze the association between Attention Deficit/Hyperactivity Disorder (ADHD) and Internet addiction (IA). METHODS: A systematic literature search was performed in four online databases in total including CENTRAL, EMBASE, PubMed and PsychINFO. Observational studies (case-control, cross-sectional and cohort studies) measuring the correlation between IA and ADHD were screened for eligibility. Two independent reviewers screened each article according to the predetermined inclusion criteria...
July 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28721826/clinical-uses-of-melatonin-in-neurological-diseases-and-mental-and-behavioural-disorders
#4
Emilio J Sánchez-Barceló, Noemi R Revilla, María D Mediavilla, Carmen Martínez-Cué, Russel J Reiter
Melatonin is a molecule with numerous properties applicable to the treatment of neurological diseases. Among these properties are the following: potent scavenger of oxygen and nitrogen reactive species, anti-inflammatory features, immuno-enhancing nature, and modulation of circadian rhythmicity. Furthermore, low concentrations of melatonin are usually found in patients with neurological diseases and mental disorders. The positive results obtained in experimental models of diverse pathologies, including diseases of the nervous system (e...
July 18, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28714195/research-review-the-role-of-obstetric-and-neonatal-complications-in-childhood-attention-deficit-and-hyperactivity-disorder-a-systematic-review
#5
Marta Serati, Jennifer L Barkin, Giulia Orsenigo, Alfredo Carlo Altamura, Massimiliano Buoli
BACKGROUND: Attention deficit and hyperactivity disorder (ADHD) is a developmental disorder characterized by an inability to sustain attention, activity levels and impulse control, and, according to the latest studies, the prevalence is about 8% and in some countries less than 1%. Currently, it is well-known that complications during the perinatal period have significant implications on child's physical and mental health. Purpose of the present paper is to review the literature about the association between perinatal complications and future risk of an ADHD diagnosis...
July 17, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28709566/selected-comorbidities-of-atopic-dermatitis-atopy-neuropsychiatric-and-musculoskeletal-disorders
#6
Jonathan I Silverberg
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial morbidity and quality of life impairment. There are a number of comorbid health problems that occur in patients with AD, aside from the cutaneous signs and symptoms. Chronic pruritus and inflammation can lead to sleep disturbances and mental health symptoms, which are not mutually exclusive. AD is associated with and may predispose to higher risk of other atopic disorders, including asthma and hay fever. Persons with AD appear to be at higher risk for multiple neuropsychiatric disorders, including depression, attention-deficit/hyperactivity disorder, speech disorders in childhood, headaches, and seizures...
July 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28709145/diagnosis-of-attention-deficit-hyperactivity-disorder-using-imaging-and-signal-processing-techniques
#7
REVIEW
Chaitra Sridhar, Shreya Bhat, U Rajendra Acharya, Hojjat Adeli, G Muralidhar Bairy
Attention Deficit Hyperactivity Disorder (ADHD) is the most common childhood psychiatric disorder that may continue through adolescence and adulthood. Hyperactivity, inattention and impulsivity are the key behavioral features observed in children with ADHD. ADHD is normally diagnosed only when a child continues to have symptoms of hyperactivity, impulsivity and inattention at a greater degree than the normal for six months or more. In recent years there has been significant research to diagnose ADHD in a quantitative way using medical imaging and signal processing techniques...
July 8, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28709018/adhd-research-in-india-a-narrative-review
#8
REVIEW
Pooja Patnaik Kuppili, Harshini Manohar, Raman Deep Pattanayak, Rajesh Sagar, Balaji Bharadwaj, Preeti Kandasamy
INTRODUCTION: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with no clear etiopathogenesis. Owing to unique socio cultural milieu of India, it is worthwhile reviewing research on ADHD from India and comparing findings with global research. Thereby, we attempted to provide a comprehensive overview of research on ADHD from India. METHODS: A boolean search of articles published in English from September 1966 to January 2017 on electronic search engines Google Scholar, PubMed, IndMED, MedIND, using the search terms "ADHD", "Attention Deficit and Hyperactivity Disorder", "Hyperactivity" ,"Child psychiatry", "Hyperkinetic disorder", "Attention Deficit Disorder", "India"was carried out and peer - reviewed studies conducted among human subjects in India were included for review...
July 5, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28705922/the-cochrane-collaboration-withdraws-a-review-on-methylphenidate-for-adults-with-attention-deficit-hyperactivity-disorder
#9
Kim Boesen, Luis Carlos Saiz, Juan Erviti, Ole Jakob Storebø, Christian Gluud, Peter C Gøtzsche, Karsten Juhl Jørgensen
A Cochrane systematic review on immediate-release methylphenidate for adults with attention deficit hyperactivity disorder (ADHD) was withdrawn from the Cochrane Library on 26 May 2016 after substantial criticism of its methods and flawed conclusions. Retraction of scientific papers on this basis is unusual but can be necessary. We provide a summary of the criticism that led to the withdrawal. We detail the methodological flaws of the withdrawn Cochrane systematic review and general issues of bias and shortcomings of the included ADHD trials: cross-over designs compared with parallel-group designs, exclusion of participants with psychiatric comorbidity, absence of 'functional outcomes' and use of clinical outcomes with limited relevance, short trial duration and small trial populations, broken blinding caused by easily recognisable side effects, combining outcome assessments by trial investigators and participants, outcome reporting bias, poor evaluation of cardiovascular and psychiatric harms and conflicts of interest of trialists and systematic reviewers...
July 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28700715/the-pharmacological-and-non-pharmacological-treatment-of-attention-deficit-hyperactivity-disorder-in-children-and-adolescents-a-systematic-review-with-network-meta-analyses-of-randomised-trials
#10
Ferrán Catalá-López, Brian Hutton, Amparo Núñez-Beltrán, Matthew J Page, Manuel Ridao, Diego Macías Saint-Gerons, Miguel A Catalá, Rafael Tabarés-Seisdedos, David Moher
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed psychiatric disorders in childhood. A wide variety of treatments have been used for the management of ADHD. We aimed to compare the efficacy and safety of pharmacological, psychological and complementary and alternative medicine interventions for the treatment of ADHD in children and adolescents. METHODS AND FINDINGS: We performed a systematic review with network meta-analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28698828/a-case-of-pediatric-post-traumatic-stress-disorder-presenting-as-attention-deficit-hyperactivity-disorder-a-case-report
#11
Muhammad A Tahir, Nida R Gujar, Nusrat Jahan
In the past few years, there has been increased recognition that children, who have faced traumatic incidences, can develop post-traumatic stress disorder (PTSD), just like in adults. We present a case of PTSD in a 6-year-old child who endured three surgical procedures because he was suffering from a congenital cranial stenosis (Pfeiffer) syndrome. Because of repetitive painful episodes, resulting from the syndrome, and then post-surgical complications, the child developed behavioral outbursts, hypervigilence, concentration problems, and irritability...
May 10, 2017: Curēus
https://www.readbyqxmd.com/read/28696032/research-review-harnessing-the-power-of-individual-participant-data-in-a-meta-analysis-of-the-benefits-and-harms-of-the-incredible-years-parenting-program
#12
REVIEW
Patty Leijten, Frances Gardner, Sabine Landau, Victoria Harris, Joanna Mann, Judy Hutchings, Jennifer Beecham, Eva-Maria Bonin, Stephen Scott
BACKGROUND: Parenting programs aim to reduce children's conduct problems through improvement of family dynamics. To date, research on the precise benefits and possible harms of parenting programs on family well-being has been unsystematic and likely to be subject to selective outcome reporting and publication bias. Better understanding of program benefits and harms requires full disclosure by researchers of all included measures, and large enough numbers of participants to be able to detect small effects and estimate them precisely...
July 11, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28695871/psychiatric-disorders-and-obesity-a-review-of-association-studies
#13
REVIEW
T M Rajan, V Menon
BACKGROUND: Inconsistent evidence exists regarding the strength, direction, and moderators in the relationship between obesity and psychiatric disorders. AIM: This study aims to summarize the evidence on the association between psychiatric illness and obesity with particular attention to the strength and direction of association and also the possible moderators in each postulated link. MATERIALS AND METHODS: Systematic electronic searches of MEDLINE through PubMed, ScienceDirect, PsycINFO, and Google Scholar were carried out from inception till October 2016...
July 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28692449/fidget-spinners-purported-benefits-adverse-effects-and-accepted-alternatives
#14
Rachel A Schecter, Jay Shah, Kate Fruitman, Ruth Lynn Milanaik
PURPOSE OF REVIEW: In the span of a few months, fidget spinners have caught the eyes of millions of children, parents, educators and paediatricians. Fidget spinners, hand-held toys designed to spin freely in your grasp, have become a source of entertainment for consumers of all ages. Despite a lack of scientific evidence, toy marketers have advertised the benefits of fidget spinners for children with attention-deficit/hyperactivity disorder and other disorders (e.g. autism, anxiety, sensory issues)...
July 7, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28683846/beyond-the-pill-new-medication-delivery-options-for-adhd
#15
Andrew J Cutler, Gregory W Mattingly
Successful treatment of pediatric disorders has necessitated the development of alternative medication formulations, as children may prefer alternative dosage forms to tablets or capsules. This is especially true for attention-deficit/hyperactivity disorder (ADHD), which is one of the most common chronic pediatric conditions and often involves children with a variety of overlapping physical, psychological, or neurodevelopmental disorders. A special challenge for developing alternative dosage forms for ADHD treatment is the incorporation of a once-daily long-acting formulation...
July 7, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28682784/the-theoretical-underpinnings-of-internet-addiction-and-its-association-with-psychopathology-in-adolescence
#16
Shawn Taylor, Sirirada Pattara-Angkoon, Schwanagorn Sirirat, Damith Woods
This paper reviews the psychological and theoretical underpinnings that might help to explain the reported relationship between Internet addiction (IA) and psychopathology in both children and adolescents. Drawing on cognitive-behavioural models and social-skills theory, IA shows a strong relationship with depression, attention deficit hyperactivity disorder (ADHD) and time spent using the Internet use. Mixed findings are reported for social anxiety. Loneliness and hostility were also found to be associated with IA...
July 6, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28674760/medical-comorbidities-in-children-and-adolescents-with-autism-spectrum-disorders-and-attention-deficit-hyperactivity-disorders-a-systematic-review
#17
REVIEW
Jet B Muskens, Fleur P Velders, Wouter G Staal
Somatic disorders occur more often in adult psychiatric patients than in the general adult population. However, in child and adolescent psychiatry this association is unclear, mainly due to a lack of integration of existing data. To address this issue, we here present a systematic review on medical comorbidity in the two major developmental disorders autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) and formulate clinical recommendations. The literature was searched using the PubMed and PsycINFO databases (2000-1 May 2016) with the keywords "[((child and adolescent) AND (Autism OR Attention Deficit Hyperactivity Disorder* OR ADHD)) AND ("Cardiovascular Diseases" [Mesh] OR "Endocrine System Diseases" [Mesh] OR "Immune System Diseases" [Mesh] OR "Neurobehavioral Manifestations" [Mesh] OR "Gastrointestinal Disorders" [Mesh] OR Somatic OR Autoimmune disease OR Nervous system disease OR Infection OR Infectious disease)]...
July 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28671333/diffusion-tensor-imaging-studies-of-attention-deficit-hyperactivity-disorder-meta-analyses-and-reflections-on-head-motion
#18
Yuta Aoki, Samuele Cortese, Francisco Xavier Castellanos
BACKGROUND: Diffusion tensor imaging studies have shown atypical fractional anisotropy (FA) in individuals with attention-deficit/hyperactivity disorder (ADHD), albeit with conflicting results. We performed meta-analyses of whole-brain voxel-based analyses (WBVBA) and tract-based spatial statistics (TBSS) studies in ADHD, along with a qualitative review of TBSS studies addressing the issue of head motion, which may bias results. METHODS: We conducted a systematic literature search (last search on April 1st, 2016) to identify studies comparing FA values between individuals with ADHD and typically developing (TD) participants...
July 3, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28666895/the-microbiome-and-disorders-of-the-central-nervous-system
#19
Valeria D Felice, Siobhain M O'Mahony
Alterations of the gut microbiota have been associated with stress-related disorders including depression and anxiety and irritable bowel syndrome (IBS). More recently, researchers have started investigating the implication of perturbation of the microbiota composition in neurodevelopmental disorders including autism spectrum disorders and Attention-Deficit Hypersensitivity Disorder (ADHD). In this review we will discuss how the microbiota is established and its functions in maintaining health. We also summarize both pre and post-natal factors that shape the developing neonatal microbiota and how they may impact on health outcomes with relevance to disorders of the central nervous system...
June 27, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28665691/dietary-dha-bioaccessibility-and-neurobehavioural-development-in-children
#20
Carlos Cardoso, Cláudia Afonso, Narcisa M Bandarra
DHA is a key nutritional n-3 polyunsaturated fatty acid (n-3 PUFA) and needs to be supplied by the human diet. High levels of DHA intake appear to reduce the risk of depression, bipolar disorder, and mood disorders. On the basis of these connections between DHA and neurological health, this paper reviews what is currently known about DHA and children neurodevelopment as well as the benefits of DHA intake to prevention of autism and behaviour disorders through a selective and representative revision of different papers ranging from pure observational studies to randomized controlled trials (RCTs)...
June 30, 2017: Critical Reviews in Food Science and Nutrition
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