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https://www.readbyqxmd.com/read/29333474/saccades-in-progressive-supranuclear-palsy-maladapted-irregular-curved-and-slow
#1
Aasef G Shaikh, Stewart A Factor, Jorge Juncos
Background and objectives: Slowed and curved rapid eye movements, saccades, are the well-known features of progressive supranuclear palsy (PSP). We hypothesized that the saccades in PSP are not only slow and curved, but they are also irregular and have timing deficits. Methods: We tested this hypothesis in 12 patients with PSP by measuring vertical and horizontal visually guided saccades using a limbus tracker. Results: Both, horizontal and vertical saccades were slow and had irregular trajectory and velocity profiles, but deficits were much more robust in vertical saccades...
September 2017: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/29318916/promoting-physical-activity-using-a-wearable-activity-tracker-in-college-students-a-cluster-randomized-controlled-trial
#2
Youngdeok Kim, Angela Lumpkin, Marc Lochbaum, Steven Stegemeier, Karla Kitten
This study examined the effects of utilizing a wearable activity tracker in a credit-based physical activity instructional program (PAIP) for promoting physical activity (PA) in college students. Fourteen PAIP courses in a large public university were randomly assigned into intervention (k = 7; n = 101) and control (k = 7; n = 86) groups. All courses focused on a core curriculum that covers basic exercise and behavioral science contents through lectures and activity sessions. A Misfit Flash activity tracker was provided to students in the intervention group...
January 10, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29303680/validity-and-reliability-evaluation-of-four-commercial-activity-trackers-step-counting-performance
#3
Katrine Hauer Tophøj, Matilde Grøndahl Petersen, Casper Sæbye, Thomas Baad-Hansen, Stefan Wagner
INTRODUCTION: Activity trackers are useful tools for physical rehabilitation purposes. Most available activity trackers are designed for fitness and wellness use, lacking in both accuracy and precision at lower speeds. Validity and reliability at all clinically relevant speeds are crucial selection criteria for use in clinical practice. The aim of this study was to assess the validity and reliability of four consumer-based activity trackers at clinical relevant walking speeds for patient groups undergoing rehabilitation...
January 5, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29295810/physical-activity-assessment-using-an-activity-tracker-in-patients-with-rheumatoid-arthritis-and-axial-spondyloarthritis-prospective-observational-study
#4
Charlotte Jacquemin, Hervé Servy, Anna Molto, Jérémie Sellam, Violaine Foltz, Frédérique Gandjbakhch, Christophe Hudry, Stéphane Mitrovic, Bruno Fautrel, Laure Gossec
BACKGROUND: Physical activity can be tracked using mobile devices and is recommended in rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) management. The World Health Organization (WHO) recommends at least 150 min per week of moderate to vigorous physical activity (MVPA). OBJECTIVE: The objectives of this study were to assess and compare physical activity and its patterns in patients with RA and axSpA using an activity tracker and to assess the feasibility of mobile devices in this population...
January 2, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29295808/a-perioperative-ehealth-program-to-enhance-postoperative-recovery-after-abdominal-surgery-process-evaluation-of-a-randomized-controlled-trial
#5
Eva van der Meij, Judith Af Huirne, A Dorien Ten Cate, Hein Bac Stockmann, Piet C Scholten, Paul Hp Davids, H Jaap Bonjer, Johannes R Anema
BACKGROUND: Electronic health (eHealth) interventions have proven effective, but implementation in clinical practice is difficult. More research focusing on the implementation process of eHealth interventions is necessary. OBJECTIVE: The objective of this study was to describe the process evaluation of a perioperative eHealth intervention, aiming to enhance recovery after laparoscopic abdominal surgery. METHODS: A process evaluation was carried out alongside a multicenter randomized controlled trial...
January 2, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29289170/an-isocenter-estimation-tool-for-proton-gantry-alignment
#6
Peter Hansen, Dongming Hu
A novel tool has been developed to automate the process of locating the isocenter, center of rotation, and sphere of confusion of a proton therapy gantry. The tool uses a Radian laser tracker to estimate how the coordinate frame of the front-end beam-line components changes as the gantry rotates. The coordinate frames serve as an empirical model of gantry flexing. Using this model, the alignment of the front and back-end beam-line components can be chosen to minimize the sphere of confusion, improving the overall beam positioning accuracy of the gantry...
December 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29285634/transient-inactivation-of-the-paraventricular-nucleus-of-the-thalamus-enhances-cue-induced-reinstatement-in-goal-trackers-but-not-sign-trackers
#7
Brittany N Kuhn, Marin S Klumpner, Ignacio R Covelo, Paolo Campus, Shelly B Flagel
RATIONALE: The paraventricular nucleus of the thalamus (PVT) has been shown to mediate cue-motivated behaviors, such as sign- and goal-tracking, as well as reinstatement of drug-seeking behavior. However, the role of the PVT in mediating individual variation in cue-induced drug-seeking behavior remains unknown. OBJECTIVES: This study aimed to determine if inactivation of the PVT differentially mediates cue-induced drug-seeking behavior in sign-trackers and goal-trackers...
December 28, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29284402/the-utility-of-personal-activity-trackers-fitbit-charge-2-on-exercise-capacity-in-patients-post-acute-coronary-syndrome-up-step-acs-trial-a-randomised-controlled-trial-protocol
#8
Jason Nogic, Paul Min Thein, James Cameron, Sam Mirzaee, Abdul Ihdayhid, Arthur Nasis
BACKGROUND: The benefits of physical activity and cardiovascular rehabilitation on the reduction of cardiovascular risk are well documented. Despite this, significant barriers and challenges remain in optimizing patient risk factors post acute coronary syndromes (ACS) and ensuring patient compliance. Consumer wearable personal activity trackers represent a cost effective and readily available technology that may aid in this endeavour. METHODS: UP-STEP ACS is a prospective single-blinded, two-arm, parallel, randomized control trial with an aim to enrol 200 patients all undertaking cardiac rehabilitation...
December 29, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29283040/-just-say-it-like-it-is-use-of-a-community-based-participatory-approach-to-develop-a-technology-driven-food-literacy-program-for-adolescents
#9
Catherine A Wickham, Elena T Carbone
FuelUp&Go! is a technology-driven food literacy program consisting of six in-person skill building sessions as well as fitness trackers, text messages, and a companion website. A community-based participatory research approach was used with adolescents who were recruited to participate in a Kid Council. Qualitative data were collected about the use of surveys, program activities, recipes, technology and text messages, and music and incentives. Changes suggested by Kid Councilmembers informed the design and development of a pilot program...
January 1, 2017: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/29274894/the-physical-activity-daily-pad-trial-the-rationale-and-design-of-a-randomized-controlled-trial-evaluating-an-internet-walking-program-to-improve-maximal-walking-distance-among-patients-with-peripheral-arterial-disease
#10
Anjana M Kumar, Angela K Lyden, Noelle E Carlozzi, Ananda Sen, Caroline R Richardson, Elizabeth A Jackson
BACKGROUND: Despite established guidelines for regular walking as a first line therapy for adults with peripheral arterial disease (PAD), most patients do not walk routinely. This paper presents the design specifications for a randomized clinical trial to examine the effectiveness of an internet-based walking program compared to a telephone intervention, or the combination (internet-based with telephone counseling) for promotion of regular walking in patients with PAD. METHODS: Sedentary adults with documented lower extremity PAD are being recruited from the University of Michigan Health System and the surrounding area...
December 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29258977/estimation-of-symptom-severity-during-chemotherapy-from-passively-sensed-data-exploratory-study
#11
Carissa A Low, Anind K Dey, Denzil Ferreira, Thomas Kamarck, Weijing Sun, Sangwon Bae, Afsaneh Doryab
BACKGROUND: Physical and psychological symptoms are common during chemotherapy in cancer patients, and real-time monitoring of these symptoms can improve patient outcomes. Sensors embedded in mobile phones and wearable activity trackers could be potentially useful in monitoring symptoms passively, with minimal patient burden. OBJECTIVE: The aim of this study was to explore whether passively sensed mobile phone and Fitbit data could be used to estimate daily symptom burden during chemotherapy...
December 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29248694/sirt3-confers-protection-against-acrolein-induced-oxidative-stress-in-cochlear-nucleus-neurons
#12
Juan Qu, Yong-Xiang Wu, Ting Zhang, Yang Qiu, Zhong-Jia Ding, Ding-Jun Zha
Acrolein is a ubiquitous dietary and environmental pollutant, which can also be generated endogenously during cellular stress. However, the molecular mechanisms underlying acrolein-induced neurotoxicity, especially in ototoxicity conditions, have not been fully determined. In this study, we investigated the mechanisms on acrolein-induced toxicity in primary cultured cochlear nucleus neurons with focus on Sirt3, a mitochondrial deacetylase. We found that acrolein treatment induced neuronal injury and programmed cell death (PCD) in a dose dependent manner in cochlear nucleus neurons, which was accompanied by increased intracellular reactive oxygen species (ROS) generation and lipid peroxidation...
December 14, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/29221112/traditional-chinese-medicine-ka-sai-ping-suppresses-the-growths-of-gastric-cancers-via-induction-of-autophagy
#13
Mo-Li Zhu, Jun-Xiu Lu, Guo-Pin Pan, Song Ping, Fan-Rong Zhao, Heng-Tian Qi, Hai-Ya Yu, Xu Jian, Guang-Rui Wan, Peng Li
Traditional Chinese medication is increasingly used to treat a wide range of human chronic diseases like cardiovascular diseases and cancers. This study was designed to explore whether ka-sai-ping (KSP), a novel traditional Chinese medicine developed by us, prevents gastric cancer growths and to investigate the underlying mechanism. The xenograft model of mouse gastric cancer was established by injecting MFCs into nude mouse subcutaneously. Cell autophagy was assessed by MDC staining. Lysosome and mitochondria were detected by Lyso-Tracker Red and Mito-Traker Green staining...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29217503/impact-of-an-electronic-health-record-integrated-personal-health-record-on-patient-participation-in-health-care-development-and-randomized-controlled-trial-of-myhealthkeeper
#14
Borim Ryu, Nari Kim, Eunyoung Heo, Sooyoung Yoo, Keehyuck Lee, Hee Hwang, Jeong-Whun Kim, Yoojung Kim, Joongseek Lee, Se Young Jung
BACKGROUND: Personal health record (PHR)-based health care management systems can improve patient engagement and data-driven medical diagnosis in a clinical setting. OBJECTIVE: The purpose of this study was (1) to demonstrate the development of an electronic health record (EHR)-tethered PHR app named MyHealthKeeper, which can retrieve data from a wearable device and deliver these data to a hospital EHR system, and (2) to study the effectiveness of a PHR data-driven clinical intervention with clinical trial results...
December 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29204293/validity-reliability-and-feasibility-of-commercially-available-activity-trackers-in-physical-therapy-for-people-with-a-chronic-disease-a-study-protocol-of-a-mixed-methods-research
#15
Emmylou Beekman, Susy M Braun, Darcy Ummels, Kim van Vijven, Albine Moser, Anna J Beurskens
Background: For older people and people with a chronic disease, physical activity provides health benefits. Patients and healthcare professionals can use commercially available activity trackers to objectively monitor (alterations in) activity levels and patterns and to support physical activity. However, insight in the validity, reliability, and feasibility of these trackers in people with a chronic disease is needed. In this article, a study protocol is described in which the validity, reliability (part A), and feasibility from a patient and therapist's point of view (part B) of commercially available activity trackers in daily life and health care is investigated...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29203953/are-heart-failure-and-coronary-artery-bypass-surgery-patients-meeting-physical-activity-guidelines
#16
COMPARATIVE STUDY
Bernice C Yates, Bunny Pozehl, Kevin Kupzyk, Crystal M Epstein, Pallav Deka
Purpose: The purpose of this study was to describe subjective and objective physical activity (PA) levels of two groups of cardiovascular patients who were either post-coronary artery bypass graft (CABG) surgery or diagnosed with heart failure (HF). Design: A descriptive comparative design was used for this secondary analysis of data from two prior studies. Methods: A convenience sample of 62 outpatients was used to examine PA objectively (Actiheart accelerometer) and subjectively (PA interview)...
May 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29201377/use-of-wearable-devices-for-post-discharge-monitoring-of-icu-patients-a-feasibility-study
#17
Ryan R Kroll, Erica D McKenzie, J Gordon Boyd, Prameet Sheth, Daniel Howes, Michael Wood, David M Maslove
Background: Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness. Methods: To determine the feasibility of using a wrist-worn personal fitness tracker among patients recovering from critical illness, we conducted a prospective observational study of a convenience sample of 50 stable ICU patients. We assessed device wearability, the extent of data capture, sensitivity and specificity for detecting heart rate excursions, and correlations with questionnaire-derived sleep quality measures...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/29198194/the-effects-of-diurnal-ramadan-fasting-on-energy-expenditure-and-substrate-oxidation-in-healthy-men
#18
Sana'a A Alsubheen, Mohammad Ismail, Alicia Baker, Jason Blair, Adeboye Adebayo, Liam Kelly, Vikram Chandurkar, Sukhinder Cheema, Denis R Joanisse, Fabien A Basset
The study aimed to examine the effects of diurnal Ramadan fasting (RF) on substrate oxidation, energy production, blood lipids and glucose as well as body composition. Nine healthy Muslim men (fasting (FAST) group) and eight healthy non-practicing men (control (CNT) group) were assessed pre- and post-RF. FAST were additionally assessed at days 10, 20 and 30 of RF in the morning and evening. Body composition was determined by hydrodensitometry, substrate oxidation and energy production by indirect calorimetry, blood metabolic profile by biochemical analyses and energy balance by activity tracker recordings and food log analyses...
December 4, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/29196085/technology-interventions-for-nonadherence-new-approaches-to-an-old-problem
#19
Bruce G Bender
Nonadherence to asthma medications is well recognized. Interventions to improve adherence, however, have been only moderately successful and are not often adopted because of limited provider time, training, or institutional support. The potential for mobile communication technology to improve adherence has gathered sharply growing interest. Technology-based adherence tracking devices have been in existence for almost 3 decades, but have only recently reached a level of reliability and utility to be considered in allergy practice...
November 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29173072/-social-networkout-connecting-social-features-of-wearable-fitness-trackers-with-physical-exercise
#20
Yaguang Zhu, Stephanie L Dailey, Daniel Kreitzberg, Jay Bernhardt
Despite widespread understanding of the benefits of physical activity, many adults in the United States do not meet recommended exercise guidelines. Burgeoning technologies, including wearable fitness trackers (e.g., Fitbit, Apple watch), bring new opportunities to influence physical activity by encouraging users to track and share physical activity data and compete against their peers. However, research has not explored the social processes that mediate the relationship between the use of wearable fitness trackers and intention to exercise...
December 2017: Journal of Health Communication
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