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https://www.readbyqxmd.com/read/28078355/-compression-therapy-of-venous-leg-ulcers-in-the-decongestion-phase
#1
REVIEW
J Dissemond, S Eder, S Läuchli, H Partsch, M Stücker, W Vanscheidt
Compression therapy is the basis for successful treatment in most patients with venous leg ulcers. Concerning compression therapy, the initial phase of decongestion and the following phase of maintenance should be differentiated. While in the maintenance phase (ulcer) stocking systems are now frequently recommended, in the decongestion phase compression bandages are mostly still used, which however are often inappropriately applied. In German-speaking countries, compression therapy with short-stretch bandages has a long tradition...
January 11, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28066942/antioxidant-status-and-expression-of-inflammatory-genes-in-gut-and-liver-of-piglets-fed-different-dietary-methionine-concentrations
#2
J O Zeitz, S Kaltenböck, E Most, K Eder
This study investigated the hypothesis that dietary concentrations of methionine (Met), as a precursor of cysteine which is a constituent of glutathione (GSH), affect tissue antioxidant concentrations and the antioxidant defence system in pigs. Forty-five piglets (DanZucht × Pietrain) were allotted to three groups of similar mean body weight (11.0 ± 0.9 kg). The basal diet was composed of barley, wheat, corn starch, soybean oil, sucrose, cellulose and a mineral supplement with suboptimal concentrations of Met and was supplemented with dl-Met to reach 0...
January 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28064396/efficient-removal-of-amoxicillin-and-paracetamol-from-aqueous-solutions-using-magnetic-activated-carbon
#3
Caroline Saucier, P Karthickeyan, V Ranjithkumar, Eder C Lima, Glaydson S Dos Reis, Irineu A S de Brum
Activated carbon (AC)/CoFe2O4 nanocomposites, MAC-1 and MAC-2, were prepared by a simple pyrolytic method using a mixture of iron(III)/cobalt(II) benzoates and iron(III)/cobalt(II) oxalates, respectively, and were used as efficient adsorbents for the removal of amoxicillin (AMX) and paracetamol (PCT) of aqueous effluents. The synthesized nanocomposites were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and transmission electron microscopy (TEM)...
January 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28061324/oral-corticosterone-administration-reduces-insulitis-but-promotes-insulin-resistance-and-hyperglycemia-in-male-nonobese-diabetic-mice
#4
Susan J Burke, Heidi M Batdorf, Adrianna E Eder, Michael D Karlstad, David H Burk, Robert C Noland, Z Elizabeth Floyd, J Jason Collier
Steroid-induced diabetes is the most common form of drug-induced hyperglycemia. Therefore, metabolic and immunological alterations associated with chronic oral corticosterone were investigated using male nonobese diabetic mice. Three weeks after corticosterone delivery, there was reduced sensitivity to insulin action measured by insulin tolerance test. Body composition measurements revealed increased fat mass and decreased lean mass. Overt hyperglycemia (>250 mg/dL) manifested 6 weeks after the start of glucocorticoid administration, whereas 100% of the mice receiving the vehicle control remained normoglycemic...
January 4, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28056024/a-double-blind-randomized-controlled-trial-of-maternal-postpartum-deworming-to-improve-infant-weight-gain-in-the-peruvian-amazon
#5
Layla S Mofid, Martín Casapía, Eder Aguilar, Hermánn Silva, Antonio Montresor, Elham Rahme, William D Fraser, Grace S Marquis, Jozef Vercruysse, Lindsay H Allen, Brittany Blouin, Hugo Razuri, Lidsky Pezo, Theresa W Gyorkos
BACKGROUND: Nutritional interventions targeting the critical growth and development period before two years of age can have the greatest impact on health trajectories over the life course. Compelling evidence has demonstrated that interventions investing in maternal health in the first 1000 days of life are beneficial for both mothers and their children. One such potential intervention is deworming integrated into maternal postpartum care in areas where soil-transmitted helminth (STH) infections are endemic...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28053905/stability-of-the-prosthetic-screws-of-three-types-of-craniofacial-prostheses-retention-systems
#6
Antonio Gabriel Lanata-Flores, Eder Alberto Sigua-Rodriguez, Douglas Rangel Goulart, Veber Luiz Bomfim-Azevedo, Sergio Olate, José Ricardo de Albergaria-Barbosa
OBJECTIVES: This study aimed to evaluate the stability of prosthetic screws from three types of craniofacial prostheses retention systems (bar-clip, ball/O-ring, and magnet) when submitted to mechanical cycling. MATERIALS AND METHODS: Twelve models of acrylic resin were used with implants placed 20 mm from each other and separated into three groups: (1) bar-clip (Sistema INP, São Paulo, Brazil), (2) ball/O-ring (Sistema INP), and (3) magnet (Metalmag, São Paulo, Brazil), with four samples in each group...
December 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28050048/editorial-lean-nafld-metabolic-obesity-with-normal-bmi%C3%A2-is-it-in-the-genes
#7
Curtis K Argo, Zachary H Henry
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. "Lean" NAFLD represents a patient subpopulation with hepatic steatosis evident on imaging with normal BMI. This paper by Feldman and Eder et al. illustrates the mild but clear metabolic differences and genetic connections in Caucasian lean NAFLD patients compared with obese NAFLD and healthy controls. Their findings highlight key similarities of lean and obese NAFLD compared with lean healthy subjects. This paper characterizes "lean" NAFLD as a unique phenotype with specific genetic associations deserving of further investigation in the greater scheme of elucidating the pathophysiology of fatty liver...
January 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28036122/soluble-st2-predicts-1-year-outcome-in-patients-undergoing-transcatheter-aortic-valve-implantation-tavi
#8
Bernhard Wernly, Michael Lichtenauer, Peter Jirak, Sarah Eder, Christian Reiter, Jürgen Kammler, Alexander Kypta, Christian Jung, Uta C Hoppe, Ulf Landmesser, Hans-Reiner Figulla, Alexander Lauten
INTRODUCTION: Soluble ST2 (sST2) has been introduced as a novel biomarker in patients suffering from heart failure for risk stratification. In this study we sought to investigate whether sST2 is useful for risk stratification and prediction of mortality in patients undergoing transcatheter aortic valve implantation (TAVI). MATERIALS AND METHODS: 274 patients undergoing TAVI were included in this study (149 female; age 80.50±0.51 years; EUROSCORE 25±1; STS Score 3...
December 30, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28035618/who-1973-grade-3-and-infiltrative-growth-pattern-proved-aberrant-e-cadherin-expression-tends-to-be-of-predictive-value-for-progression-in-a-series-of-stage-t1-high-grade-bladder-cancer-after-organ-sparing-approach
#9
Wolfgang Otto, Johannes Breyer, Sonja Herdegen, Fabian Eder, Simone Bertz, Matthias May, Roman Mayr, Eva M Lausenmeyer, Stefan Denzinger, Bas W G van Rhijn, Maximilian Burger, Arndt Hartmann
PURPOSE: Stage pT1 urothelial bladder cancer (UBC) is characterized as a challenging subentity of urothelial carcinoma with an unforeseeable clinical course. In addition to more or less established clinical and histopathological features, we evaluated the role of epithelial-mesenchymal transition (EMT) marker E-cadherin, shown to be of prognostic value in muscle-invasive disease, regarding the prognosis of stage pT1 high-grade (hg) UBC. METHODS: Tissue of 226 stage pT1 hg UBC patients from transurethral resection could be immunostained for E-cadherin...
December 29, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/28007428/topical-azithromycin-for-the-prevention-of-lyme-borreliosis-a-randomised-placebo-controlled-phase-3-efficacy-trial
#10
Michael Schwameis, Thomas Kündig, Gustave Huber, Luzi von Bidder, Lorenz Meinel, Roland Weisser, Elisabeth Aberer, Georg Härter, Thomas Weinke, Tomas Jelinek, Gerd Fätkenheuer, Uwe Wollina, Gerd-Dieter Burchard, Roland Aschoff, Ruth Nischik, Gerhard Sattler, Georg Popp, Wolfgang Lotte, Dirk Wiechert, Gerald Eder, Olga Maus, Petra Staubach-Renz, Andrea Gräfe, Veronika Geigenberger, Ingomar Naudts, Michael Sebastian, Norbert Reider, Ridwan Weber, Marc Heckmann, Emil C Reisinger, Georg Klein, Johannes Wantzen, Bernd Jilma
BACKGROUND: Lyme borreliosis develops in 1-5% of individuals bitten by ticks, but with a diagnostic gap affecting up to 30% of patients, a broadly applicable pharmacological prevention strategy is needed. Topical azithromycin effectively eradicated Borrelia burgdorferi sensu lato from the skin in preclinical studies. We assessed its efficacy in human beings. METHODS: In this randomised, double-blind, placebo-controlled, multicentre trial done in 28 study sites in Germany and Austria, adults were equally assigned to receive topical 10% azithromycin or placebo twice daily for 3 consecutive days, within 72 h of a tick bite being confirmed...
December 19, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28005817/pemphigus-vulgaris-how-to-perform-an-oral-biopsy-properly
#11
Aneliza de Fatima Moraes da Silva, Daniel Galera Bernabé, Glauco Issamu Miyahara, Eder Ricardo Biasoli, Renata Callestini, Kellen Cristine Tjioe
Oral biopsy of vesiculobullous diseases such as pemphigus vulgaris often raises questions due to some particularities involving this procedure. The adequate selection of the area to be biopsied defines if the final diagnosis will be reached, being the Achiles heel of the proper management of the patient. Here, the authors report a case of a woman who sought for treatment of generalized oral blisters and ulcers that caused severe pain. She had undergone a previous biopsy by other professionals that was inconclusive...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27992507/trpc4%C3%AE-and-trpc4%C3%AE-similarly-affect-neonatal-cardiomyocyte-survival-during-chronic-gpcr-stimulation
#12
Nadine Kirschmer, Sandra Bandleon, Viktor von Ehrlich-Treuenstätt, Sonja Hartmann, Alice Schaaf, Anna-Karina Lamprecht, Erick Miranda-Laferte, Tanja Langsenlehner, Oliver Ritter, Petra Eder
The Transient Receptor Potential Channel Subunit 4 (TRPC4) has been considered as a crucial Ca2+ component in cardiomyocytes promoting structural and functional remodeling in the course of pathological cardiac hypertrophy. TRPC4 assembles as homo or hetero-tetramer in the plasma membrane, allowing a non-selective Na+ and Ca2+ influx. Gαq protein-coupled receptor (GPCR) stimulation is known to increase TRPC4 channel activity and a TRPC4-mediated Ca2+ influx which has been regarded as ideal Ca2+ source for calcineurin and subsequent nuclear factor of activated T-cells (NFAT) activation...
2016: PloS One
https://www.readbyqxmd.com/read/27992239/differential-effects-of-two-rehabilitation-programs-following-anterior-cruciate-ligament-reconstruction
#13
Igor Setuain, Mikel Izquierdo, Fernando Idoate, Eder Bikandi, Esteban M Gorostiaga, Per Aagaard, Eduardo L Cadore, Jesús Alfaro-Adrián
Context- The muscular function restoration related to the type of physical rehabilitation followed after anterior cruciate ligament reconstruction (ACLR) using autologous hamstring tendon graft in terms of strength and cross sectional area (CSA) remain controversial. Objective- To analyze the CSA and force output of quadriceps and hamstring muscles in subjects following either an Objective Criteria-Based rehabilitation (OCBR) algorithm or the usual care (UCR) for ACL rehabilitation in Spain, before and one year after undergoing an ACLR...
December 19, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27992011/muscular-cysticercosis-case-report-and-imaging-findings
#14
Neide Regina Simões Olmo, Ulysses Ferreira Fiorio, Eder Amaral Bastos, Marcel Andreazza Clemente, Gustavo Gomes Mendes
Cysticercosis is a parasitic disease caused by a worm of the Cestoda class. The most prevalent form affects the nervous system. This case report is from a 78-year-old female patient evaluated at Clínica Mult Imagem, in the city of Santos, Brazil, who presented a form of the disease that differed from the classic neurocysticercosis, in this case muscular cysticercosis. This and other forms of manifestation justify further studies to ensure adequate recognition, diagnosis and treatment of this parasitic disease...
November 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27988802/local-recurrence-of-prostate-cancer-after-radical-prostatectomy-is-at-risk-to-be-missed-in-68-ga-psma-11-pet-of-pet-ct-and-pet-mri-comparison-with-mpmri-integrated-in-simultaneous-pet-mri
#15
Martin T Freitag, Jan P Radtke, Ali Afshar-Oromieh, Matthias C Roethke, Boris A Hadaschik, Martin Gleave, David Bonekamp, Klaus Kopka, Matthias Eder, Thorsten Heusser, Marc Kachelriess, Kathrin Wieczorek, Christos Sachpekidis, Paul Flechsig, Frederik Giesel, Markus Hohenfellner, Uwe Haberkorn, Heinz-Peter Schlemmer, A Dimitrakopoulou-Strauss
PURPOSE: The positron emission tomography (PET) tracer (68)Ga-PSMA-11, targeting the prostate-specific membrane antigen (PSMA), is rapidly excreted into the urinary tract. This leads to significant radioactivity in the bladder, which may limit the PET-detection of local recurrence (LR) of prostate cancer (PC) after radical prostatectomy (RP), developing in close proximity to the bladder. Here, we analyze if there is additional value of multi-parametric magnetic resonance imaging (mpMRI) compared to the (68)Ga-PSMA-11-PET-component of PET/CT or PET/MRI to detect LR...
December 17, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27987836/chemical-structure-antiproliferative-and-antioxidant-activities-of-a-cell-wall-%C3%AE-d-mannan-from-yeast-kluyveromyces-marxianus
#16
Éder Galinari, Diego Araújo Sabry, Guilherme Lanzi Sassaki, Gorete Ribeiro Macedo, Flávia Maria Lopes Passos, Hilário Cuquetto Mantovani, Hugo Alexandre Oliveira Rocha
Cell wall polysaccharides from filamentous fungi and yeasts have been reported as antioxidant and antiproliferative polymers. Thus, we evaluated these activities from cell wall polysaccharides from Kluyveromyces marxianus CCT7735. By using a centrifugal filter, a 203kDa α-d-mannan (KMM-5) was obtained. KMM-5 exhibited no effect on HeLa cells and a weak antiproliferative activity against Hep-G2 cells. In addition, at higher concentrations, it presented a cytotoxicity to the normal cell line, 3T3. However, KMM-5 showed copper- and iron-chelating abilities, the latter of which presented improved activity...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27971208/overview-of-the-budget-impact-analysis-of-drugs-in-hungary-and-internationally
#17
B Eder, B Nagy
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27971082/the-normal-reimbursement-procedure-of-the-pharmaceutical-submissions-between-2013-and-2015-in-hungary-needs-and-results
#18
A Csordás, O Lőrincz, B Éder
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27958372/global-map-of-oxytocin-vasopressin-like-neuropeptide-signalling-in-insects
#19
Zita Liutkeviciute, Johannes Koehbach, Thomas Eder, Esther Gil-Mansilla, Christian W Gruber
Oxytocin and vasopressin mediate a range of physiological functions that are important for osmoregulation, reproduction, social behaviour, memory and learning. The origin of this signalling system is thought to date back ~600 million years. Oxytocin/vasopressin-like peptides have been identified in several invertebrate species and they appear to be functionally related across the entire animal kingdom. There is little information available about the biology of this peptide G protein-coupled receptor signalling system in insects...
December 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27935310/reduction-of-selenoamides-to-amines-using-smi2-h2o
#20
Samuel Thurow, Eder J Lenardão, Xavier Just-Baringo, David J Procter
Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary, and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.
December 9, 2016: Organic Letters
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