Jun-Wei Zheng, Si-Zhi Ai, Su-Hua Chang, Shi-Qiu Meng, Le Shi, Jia-Hui Deng, Tian-Qi Di, Wang-Yue Liu, Xiang-Wen Chang, Jing-Li Yue, Xiao-Qin Yang, Na Zeng, Yan-Ping Bao, Yan Sun, Lin Lu, Jie Shi
Previous studies have shown that excessive alcohol consumption is associated with poor sleep. However, the health risks of light-to-moderate alcohol consumption in relation to sleep traits (e.g., insomnia, snoring, sleep duration and chronotype) remain undefined, and their causality is still unclear in the general population. To identify the association between alcohol consumption and multiple sleep traits using an observational and Mendelian randomization (MR) design. Observational analyses and one-sample MR (linear and nonlinear) were performed using clinical and individual-level genetic data from the UK Biobank (UKB)...
January 18, 2024: Molecular Psychiatry