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https://www.readbyqxmd.com/read/29210942/auditory-related-resting-state-fmri-functional-connectivity-in-tinnitus-patients-tinnitus-diagnosis-performance
#1
Shujiro B Minami, Naoki Oishi, Takahisa Watabe, Kimiichi Uno, Kaoru Ogawa
OBJECTIVE: The purpose of the present study was to investigate functional connectivity in tinnitus patients with and without hearing loss, and design the tinnitus diagnosis performance by resting state functional magnetic resonance imaging (rs-fMRI). SUBJECTS AND METHODS: Nineteen volunteers with normal hearing without tinnitus, 18 tinnitus patients with hearing loss, and 11 tinnitus patients without hearing loss were enrolled in this study. The subjects were evaluated with rs-fMRI, and region of interests (ROIs) based correlation analyses were performed using the CONN toolbox version 16 and SPM version 8...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29209199/decreased-complexity-in-alzheimer-s-disease-resting-state-fmri-evidence-of-brain-entropy-mapping
#2
Bin Wang, Yan Niu, Liwen Miao, Rui Cao, Pengfei Yan, Hao Guo, Dandan Li, Yuxiang Guo, Tianyi Yan, Jinglong Wu, Jie Xiang, Hui Zhang
Alzheimer's disease (AD) is a frequently observed, irreversible brain function disorder among elderly individuals. Resting-state functional magnetic resonance imaging (rs-fMRI) has been introduced as an alternative approach to assessing brain functional abnormalities in AD patients. However, alterations in the brain rs-fMRI signal complexities in mild cognitive impairment (MCI) and AD patients remain unclear. Here, we described the novel application of permutation entropy (PE) to investigate the abnormal complexity of rs-fMRI signals in MCI and AD patients...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29205574/different-pre-scanning-instructions-induce-distinct-psychological-and-resting-brain-states-during-functional-magnetic-resonance-imaging
#3
Toshikazu Kawagoe, Keiichi Onoda, Shuhei Yamaguchi
Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used to investigate functional brain network connectivity during rest or when the subject is not performing an explicit task. In the standard procedure, subjects are instructed to "let your mind wander" or "think of nothing." While these instructions appear appropriate to induce a "resting-state," they could induce distinct psychological and physiological states during the scan. In this study, we investigated whether different instructions affect mental state and functional connectivity (FC) (i...
December 4, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29198588/how-much-is-enough-can-resting-state-fmri-provide-a-demarcation-for-neurosurgical-resection-in-glioma
#4
REVIEW
Diana C Ghinda, Jin-Song Wu, Niall W Duncan, Georg Northoff
This study represents a systematic review of the insights provided by resting state functional MRI (rs-fMRI) use in the glioma population. Following PRISMA guidelines, 45 studies were included in the review and were classified in glioma-related neuronal changes (n=28) and eloquent area localization (n=17). Despite the heterogeneous nature of the studies, there is considerable evidence of diffuse functional reorganization occurring in the setting of gliomas with local and interhemispheric functional connectivity alterations involving different functional networks...
November 30, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29182621/exploring-the-reproducibility-of-functional-connectivity-alterations-in-parkinson-s-disease
#5
Liviu Badea, Mihaela Onu, Tao Wu, Adina Roceanu, Ovidiu Bajenaru
Since anatomic MRI is presently not able to directly discern neuronal loss in Parkinson's Disease (PD), studying the associated functional connectivity (FC) changes seems a promising approach toward developing non-invasive and non-radioactive neuroimaging markers for this disease. While several groups have reported such FC changes in PD, there are also significant discrepancies between studies. Investigating the reproducibility of PD-related FC changes on independent datasets is therefore of crucial importance...
2017: PloS One
https://www.readbyqxmd.com/read/29181274/assessment-of-brain-functional-connectome-alternations-and-correlation-with-depression-and-anxiety-in-major-depressive-disorders
#6
Vincent Chin-Hung Chen, Chao-Yu Shen, Sophie Hsin-Yi Liang, Zhen-Hui Li, Ming-Hong Hsieh, Yeu-Sheng Tyan, Mong-Liang Lu, Yena Lee, Roger S McIntyre, Jun-Cheng Weng
Major depressive disorder (MDD) is highly prevalent, recurrent, and associated with functional impairment, morbidity, and mortality. Herein, we aimed to identify disruptions in functional connectomics among subjects with MDD by using resting-state functional magnetic resonance imaging (rs-fMRI). Sixteen subjects with MDD and thirty health controls completed resting-state fMRI scans and clinical assessments (e.g., Hamilton Depression Rating Scale (HAMD) and Hospital Anxiety and Depression Scale (HADS)). We found higher amplitude of low frequency fluctuations (ALFF) bilaterally in the hippocampus and amygdala among MDD subjects when compared to healthy controls...
2017: PeerJ
https://www.readbyqxmd.com/read/29179629/spinal-cord-injury-disrupts-resting-state-networks-in-the-human-brain
#7
Ammar Hawasli, Jerrel Rutlin, Jarod L Roland, Rory Murphy, Sheng-Kwei Song, Eric Leuthardt, Joshua Shimony, Wilson Z Ray
Despite 253,000 spinal cord injury (SCI) patients in America, little is known about how SCI affects brain networks. Spinal magnetic resonance imaging (MRI) provides only structural information with no insight into functional connectivity. Resting-state functional MRI (RS-fMRI) quantifies network connectivity through the identification of resting-state networks (RSNs) and allows detection of functionally-relevant changes during disease. Given the robust network of spinal cord afferents to the brain, we hypothesized SCI produces meaningful changes in brain RSNs...
November 27, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29175032/convergent-and-divergent-functional-connectivity-patterns-in-patients-with-long-term-left-sided-and-right-sided-deafness
#8
Yanyang Zhang, Zhiqi Mao, Shiyu Feng, Wenxin Wang, Jun Zhang, Xinguang Yu
Cortical reorganization may be induced in long-term single-sided deafness (SD); however, the influence of the deafness side on the functional changes remains poorly understood. Here, we investigated whole-brain functional connectivity patterns in long-term SD patients. The normalized voxel-based functional connectivity strength (FCS) was determined using resting-state fMRI (rs-fMRI) in 17 left-sided deafness (LD) patients, 21 right-sided deafness (RD) patients and 21 healthy controls (HCs). Relative to the HCs, both the LD and RD patients exhibited a reduction in the FCS in the ipsilateral visual cortex...
November 22, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29171429/age-related-connectivity-differences-between-attention-deficit-and-hyperactivity-disorder-patients-and-typically-developing-subjects-a-resting-state-functional-mri-study
#9
Jisu Hong, Bo-Yong Park, Hwan-Ho Cho, Hyunjin Park
Attention deficit and hyperactivity disorder (ADHD) is a disorder characterized by behavioral symptoms including hyperactivity/impulsivity among children, adolescents, and adults. These ADHD related symptoms are influenced by the complex interaction of brain networks which were under explored. We explored age-related brain network differences between ADHD patients and typically developing (TD) subjects using resting state fMRI (rs-fMRI) for three age groups of children, adolescents, and adults. We collected rs-fMRI data from 184 individuals (27 ADHD children and 31 TD children; 32 ADHD adolescents and 32 TD adolescents; and 31 ADHD adults and 31 TD adults)...
October 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29163844/identifying-current-and-remitted-major-depressive-disorder-with-the-hurst-exponent-a-comparative-study-on-two-automated-anatomical-labeling-atlases
#10
Bin Jing, Zhuqing Long, Han Liu, Huagang Yan, Jianxin Dong, Xiao Mo, Dan Li, Chunhong Liu, Haiyun Li
Major depressive disorder (MDD) is a leading world-wide psychiatric disorder with high recurrence rate, therefore, it is desirable to identify current MDD (cMDD) and remitted MDD (rMDD) for their appropriate therapeutic interventions. In the study, 19 cMDD, 19 rMDD and 19 well-matched healthy controls (HC) were enrolled and scanned with the resting-state functional magnetic resonance imaging (rs-fMRI). The Hurst exponent (HE) of rs-fMRI in AAL-90 and AAL-1024 atlases were calculated and compared between groups...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29154684/brain-functional-connectivity-in-headache-disorders-a-narrative-review-of-mri-investigations
#11
Catherine D Chong, Todd J Schwedt, Anders Hougaard
Resting-state functional magnetic resonance imaging (rs-fMRI) is used to interrogate the functional connectivity and network organization amongst brain regions. Functional connectivity is determined by measuring the extent of synchronization in the spontaneous fluctuations of blood oxygenation level dependent (BOLD) signal. Here, we review current rs-fMRI studies in headache disorders including migraine, trigeminal autonomic cephalalgias, and medication overuse headache. We discuss (1) brain network alterations that are shared amongst the different headache disorders and (2) network abnormalities distinct to each headache disorder...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29149191/resting-state-fmri-in-sleeping-infants-more-closely-resembles-adult-sleep-than-adult-wakefulness
#12
Anish Mitra, Abraham Z Snyder, Enzo Tagliazucchi, Helmut Laufs, Jed Elison, Robert W Emerson, Mark D Shen, Jason J Wolff, Kelly N Botteron, Stephen Dager, Annette M Estes, Alan Evans, Guido Gerig, Heather C Hazlett, Sarah J Paterson, Robert T Schultz, Martin A Styner, Lonnie Zwaigenbaum, Bradley L Schlaggar, Joseph Piven, John R Pruett, Marcus Raichle
Resting state functional magnetic resonance imaging (rs-fMRI) in infants enables important studies of functional brain organization early in human development. However, rs-fMRI in infants has universally been obtained during sleep to reduce participant motion artifact, raising the question of whether differences in functional organization between awake adults and sleeping infants that are commonly attributed to development may instead derive, at least in part, from sleep. This question is especially important as rs-fMRI differences in adult wake vs...
2017: PloS One
https://www.readbyqxmd.com/read/29117709/detecting-perfusion-pattern-based-on-the-background-low-frequency-fluctuation-in-resting-state-functional-mri-data-and-its-influence-on-resting-state-networks-an-iterative-post-processing-approach
#13
Tianyi Qian, Davide Zanchi, Cristelle Rodriguez, Marine Ackermann, Panteleimon Giannakopoulos, Sven Haller
INTRODUCTION: RS-fMRI is based on the assumption that the vascular response and the blood oxygenation level dependent (BOLD) response are homogenous across the entire brain. However, this a priori hypothesis is not consistent with the well-known variability of cerebral vascular territories. In order to explore whether the RS networks are influenced by varied vascular speed in different vascular territories, we assessed the time-shift maps that give an estimate of the local timing of the vascular response and check whether local differences in this timing have an impact on the estimates of RS networks...
November 8, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29117581/collective-sparse-symmetric-non-negative-matrix-factorization-for-identifying-overlapping-communities-in-resting-state-brain-functional-networks
#14
Xuan Li, John Q Gan, Haixian Wang
Resting-state functional magnetic resonance imaging (rs-fMRI) provides a valuable tool to study spontaneous brain activity. Using rs-fMRI, researchers have extensively studied the organization of the brain functional network and found several consistent communities consisting of functionally connected but spatially separated brain regions across subjects. However, increasing evidence in many disciplines has shown that most realistic complex networks have overlapping community structure. Only recently has the overlapping community structure drawn increasing interest in the domain of brain network studies...
November 5, 2017: NeuroImage
https://www.readbyqxmd.com/read/29113397/altered-putamen-functional-connectivity-is-associated-with-anxiety-disorder-in-parkinson-s-disease
#15
Xixi Wang, Junyi Li, Yongsheng Yuan, Min Wang, Jian Ding, Jiejin Zhang, Lin Zhu, Yuting Shen, Hui Zhang, Kezhong Zhang
In this study, we used resting state-functional magnetic resonance imaging (rs-fMRI) to explore altered putamen functional connectivity (FC) in Parkinson's disease patients with anxiety disorder. We divided 65 Parkinson's disease patients into anxiety (PD-A; n=18) and non-anxiety (PD-NA; n=45) groups based on a Hamilton Anxiety Rating Scale cutoff score of 12. The PD-A patients exhibited altered putamen FC with cortical and subcortical regions. The PD-A patients showed enhanced putamen FC with the caudatum, which correlated with increased emotional processing during anxiety...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29113386/chemotherapy-induced-changes-of-cerebral-activity-in-resting-state-functional-magnetic-resonance-imaging-and-cerebral-white-matter-in-diffusion-tensor-imaging
#16
Caiqin Mo, Hailong Lin, Fangmeng Fu, Lin Lin, Jie Zhang, Meng Huang, Chuan Wang, Yunjing Xue, Qing Duan, Weiwen Lin, Xiangjin Chen
While chemotherapy related cognitive disorder has been described in many studies, but we still lack relatively reliable and objective diagnostic tools, and there are few similar studies in Asian patients. We recruited Asian breast cancer patients to perform a cohort study to uncover chemotherapy related cognitive disorder by using resting-state functioning magnetic resonance imaging (RS-fMRI) and magnetic resonance diffusion tensor imaging (DTI) combined with neuropsychologic assessments. This is the first prospective study which combines RS-fMRI and DTI to detect chemotherapy related cognitive disorder...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29111359/role-of-spontaneous-brain-activity-in-explicit-and-implicit-aspects-of-cognitive-flexibility-under-socially-conflicting-situations-a-resting-state-fmri-study-using-fractional-amplitude-of-low-frequency-fluctuations
#17
Junya Fujino, Shisei Tei, Kathryn F Jankowski, Ryosaku Kawada, Toshiya Murai, Hidehiko Takahashi
We are constantly exposed to socially conflicting situations in everyday life, and cognitive flexibility is essential for adaptively coping with such difficulties. Flexible goal choice and pursuit are not exclusively conscious, and therefore cognitive flexibility involves both explicit and implicit forms of processing. However, it is unclear how individual differences in explicit and implicit aspects of flexibility are associated with neural activity in a resting state. Here, we measured intrinsic fractional amplitude of low-frequency fluctuations (fALFF) by resting-state functional magnetic resonance imaging (RS-fMRI) as an indicator of regional brain spontaneous activity, together with explicit and implicit aspects of cognitive flexibility using the Cognitive Flexibility Scale (CFS) and Implicit Association Test (IAT)...
October 27, 2017: Neuroscience
https://www.readbyqxmd.com/read/29110183/integrated-cross-network-connectivity-of-amygdala-insula-and-subgenual-cingulate-associated-with-facial-emotion-perception-in-healthy-controls-and-remitted-major-depressive-disorder
#18
Lisanne M Jenkins, Jonathan P Stange, Alyssa Barba, Sophie R DelDonno, Leah R Kling, Emily M BriceƱo, Sara L Weisenbach, K Luan Phan, Stewart A Shankman, Robert C Welsh, Scott A Langenecker
Emotion perception deficits could be due to disrupted connectivity of key nodes in the salience and emotion network (SEN), including the amygdala, subgenual anterior cingulate cortex (sgACC), and insula. We examined SEN resting-state (rs-)fMRI connectivity in rMDD in relation to Facial Emotion Perception Test (FEPT) performance. Fifty-two medication-free people ages 18 to 23 years participated. Twenty-seven had major depressive disorder (MDD) in remission (rMDD, 10 males), as MDD is associated with emotion perception deficits and alterations in rsfMRI...
November 6, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29094774/perinatal-maternal-depressive-symptoms-alter-amygdala-functional-connectivity-in-girls
#19
Ni Ni Soe, Daniel J Wen, Joann S Poh, Yap-Seng Chong, Birit Fp Broekman, Helen Chen, Lynette P Shek, Kok Hian Tan, Peter D Gluckman, Marielle V Fortier, Michael J Meaney, Anqi Qiu
Perinatal maternal depressive symptoms influence brain development of offspring. Such effects are particularly notable in the amygdala, a key structure involved in emotional processes. This study investigated whether the functional organization of the amygdala varies as a function of pre- and postnatal maternal depressive symptoms. The amygdala functional network was assessed using resting-state functional magnetic resonance imaging (rs-fMRI) in 128 children at age of 4.4 to 4.8 years. Maternal depressive symptoms were obtained at 26 weeks of gestation, 3 months, 1, 2, 3, and 4...
November 2, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29090337/structure-function-relationships-during-segregated-and-integrated-network-states-of-human-brain-functional-connectivity
#20
Makoto Fukushima, Richard F Betzel, Ye He, Martijn P van den Heuvel, Xi-Nian Zuo, Olaf Sporns
Structural white matter connections are thought to facilitate integration of neural information across functionally segregated systems. Recent studies have demonstrated that changes in the balance between segregation and integration in brain networks can be tracked by time-resolved functional connectivity derived from resting-state functional magnetic resonance imaging (rs-fMRI) data and that fluctuations between segregated and integrated network states are related to human behavior. However, how these network states relate to structural connectivity is largely unknown...
October 31, 2017: Brain Structure & Function
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