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https://www.readbyqxmd.com/read/29456489/hurst-exponent-analysis-of-resting-state-fmri-signal-complexity-across-the-adult-lifespan
#1
Jianxin Dong, Bin Jing, Xiangyu Ma, Han Liu, Xiao Mo, Haiyun Li
Exploring functional information among various brain regions across time enables understanding of healthy aging process and holds great promise for age-related brain disease diagnosis. This paper proposed a method to explore fractal complexity of the resting-state functional magnetic resonance imaging (rs-fMRI) signal in the human brain across the adult lifespan using Hurst exponent (HE). We took advantage of the examined rs-fMRI data from 116 adults 19 to 85 years of age (44.3 ± 19.4 years, 49 females) from NKI/Rockland sample...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29455363/predicting-autism-spectrum-disorder-using-domain-adaptive-cross-site-evaluation
#2
Runa Bhaumik, Ashish Pradhan, Soptik Das, Dulal K Bhaumik
The advances in neuroimaging methods reveal that resting-state functional fMRI (rs-fMRI) connectivity measures can be potential diagnostic biomarkers for autism spectrum disorder (ASD). Recent data sharing projects help us replicating the robustness of these biomarkers in different acquisition conditions or preprocessing steps across larger numbers of individuals or sites. It is necessary to validate the previous results by using data from multiple sites by diminishing the site variations. We investigated partial least square regression (PLS), a domain adaptive method to adjust the effects of multicenter acquisition...
February 17, 2018: Neuroinformatics
https://www.readbyqxmd.com/read/29454933/effects-of-resting-state-condition-on-reliability-trait-specificity-and-network-connectivity-of-brain-function-measured-with-arterial-spin-labeled-perfusion-mri
#3
Zhengjun Li, Marta Vidorreta, Natalie Katchmar, David C Alsop, Daniel H Wolf, John A Detre
Resting state fMRI (rs-fMRI) provides imaging biomarkers of task-independent brain function that can be associated with clinical variables or modulated by interventions such as behavioral training or pharmacological manipulations. These biomarkers include time-averaged regional brain function as manifested by regional cerebral blood flow (CBF) measured using arterial spin labeled (ASL) perfusion MRI and correlated temporal fluctuations of function across brain networks with either ASL or blood oxygenation level dependent (BOLD) fMRI...
February 15, 2018: NeuroImage
https://www.readbyqxmd.com/read/29452265/characterizing-the-modulation-of-resting-state-fmri-metrics-by-baseline-physiology
#4
Powell P W Chu, Ali M Golestani, Jonathan B Kwinta, Yasha B Khatamian, J Jean Chen
The blood-oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) signal is commonly used to assess functional connectivity across brain regions, particularly in the resting state (rs-fMRI). However, the BOLD fMRI signal is not merely a representation of neural activity, but a combination of neural activity and vascular response. These aspects of the BOLD signal are easily influenced by systemic physiology, potentially biasing BOLD-based functional connectivity measurements. In this work, we focus on the following physiological modulators of the BOLD signal: cerebral blood flow (CBF), venous blood oxygenation, and cerebrovascular reactivity (CVR)...
February 13, 2018: NeuroImage
https://www.readbyqxmd.com/read/29439328/impact-of-total-knee-arthroplasty-with-general-anesthesia-on-brain-networks-cognitive-efficiency-and-ventricular-volume-predict-functional-connectivity-decline-in-older-adults
#5
Haiqing Huang, Jared Tanner, Hari Parvataneni, Mark Rice, Ann Horgas, Mingzhou Ding, Catherine Price
 Using resting state functional magnetic resonance imaging (RS-fMRI), we explored: 1) pre- to post-operative changes in functional connectivity in default mode, salience, and central executive networks after total knee arthroplasty (TKA) with general anesthesia, and 2) the contribution of cognitive/brain reserve metrics these resting state functional declines. Individuals age 60 and older electing unilateral total knee arthroplasty (TKA; n = 48) and non-surgery peers with osteoarthritis (n = 45) completed baseline cognitive testing and baseline and post-surgery (post-baseline, 48-h post-surgery) brain MRI...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29437252/high-temporal-resolution-motion-estimation-using-a-self-navigated-simultaneous-multi-slice-echo-planar-imaging-acquisition
#6
Jose R Teruel, Joshua M Kuperman, Anders M Dale, Nathan S White
BACKGROUND: Subject motion is known to produce spurious covariance among time-series in functional connectivity that has been reported to induce distance-dependent spurious correlations. PURPOSE: To present a feasibility study for applying the extended Kalman filter (EKF) framework for high temporal resolution motion correction of resting state functional MRI (rs-fMRI) series using each simultaneous multi-slice (SMS) echo planar imaging (EPI) shot as its own navigator...
February 13, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29436054/sensorimotor-network-alterations-in-children-and-youth-with-prenatal-alcohol-exposure
#7
Xiangyu Long, Graham Little, Christian Beaulieu, Catherine Lebel
Children with prenatal alcohol exposure (PAE) often have impaired sensorimotor function. While altered brain structure has been noted in sensorimotor areas, the functional brain alterations remain unclear. This study aims to investigate sensorimotor brain networks in children and youth with PAE using resting-state functional magnetic resonance imaging (rs-fMRI). A parcellation-based network analysis was performed to identify brain networks related to hand/lower limb and face/upper limb function in 59 children and youth with PAE and 50 typically developing controls...
February 12, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29430573/learning-based-estimation-of-functional-correlation-tensors-in-white-matter-for-early-diagnosis-of-mild-cognitive-impairment
#8
Lichi Zhang, Han Zhang, Xiaobo Chen, Qian Wang, Pew-Thian Yap, Dinggang Shen
It has been recently demonstrated that the local BOLD signals in resting-state fMRI (rs-fMRI) can be captured for the white matter (WM) by functional correlation tensors (FCTs). FCTs provide similar orientation information as diffusion tensors (DTs), and also functional information concerning brain dynamics. However, FCTs are susceptible to noise due to the low signal-to-noise ratio nature of WM BOLD signals. Here we introduce a robust FCT estimation method to facilitate individualized diagnosis. First, we develop a noise-tolerating patch-based approach to measure spatiotemporal correlations of local BOLD signals...
September 2017: Patch-Based Techniques in Medical Imaging: Third International Workshop, Patch-MI 2017, Held in Conjunction with MICCAI 2017, Quebec City, QC, Canada, September 14, 2017, Proceedings
https://www.readbyqxmd.com/read/29427365/neural-and-behavioral-correlates-of-negative-self-focused-thought-associated-with-depression
#9
Carissa L Philippi, M Daniela Cornejo, Carlton P Frost, Erin C Walsh, Roxanne M Hoks, Rasmus Birn, Heather C Abercrombie
A central feature of major depression (MDD) is heightened negative self-focused thought (negative-SFT). Neuroscientific research has identified abnormalities in a network of brain regions in MDD, including brain areas associated with SFT such as medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC). To our knowledge no studies have investigated the behavioral and neural correlates of negative-SFT using a sentence completion task in a sample of individuals with varying depression histories and severities...
February 9, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29427063/functional-brain-abnormalities-in-major-depressive-disorder-using-the-hilbert-huang-transform
#10
Haibin Yu, Feng Li, Tong Wu, Rui Li, Li Yao, Chuanyue Wang, Xia Wu
Major depressive disorder is a common disease worldwide, which is characterized by significant and persistent depression. Non-invasive accessory diagnosis of depression can be performed by resting-state functional magnetic resonance imaging (rs-fMRI). However, the fMRI signal may not satisfy linearity and stationarity. The Hilbert-Huang transform (HHT) is an adaptive time-frequency localization analysis method suitable for nonlinear and non-stationary signals. The objective of this study was to apply the HHT to rs-fMRI to find the abnormal brain areas of patients with depression...
February 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29425918/age-and-hiv-effects-on-resting-state-of-the-brain-in-relationship-to-neurocognitive-functioning
#11
Anna R Egbert, Bharat Biswal, Keerthana Karunakaran, Suril Gohel, Agnieszka Pluta, Tomasz Wolak, Bogna Szymańska, Ewa Firląg-Burkacka, Marta Sobańska, Natalia Gawron, Przemysław Bieńkowski, Halina Sienkiewicz-Jarosz, Anna Ścińska-Bieńkowska, Robert Bornstein, Stephen Rao, Emilia Łojek
This study examined the effects of age and HIV infection on the resting state (RS) functional connectivity (FC) of the brain and cognitive functioning. The objective was to evaluate the moderating role of age and HIV on the relationship between RS-FC and cognition. To examine RS-FC we implemented the Independent Component Analysis (ICA) and Regional Homogeneity (ReHo). Neurocognition was evaluated with comprehensive battery of standardized neuropsychological tests. Age and HIV were entered as the independent variables...
February 6, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29423004/herpes-zoster-chronification-to-postherpetic-neuralgia-induces-brain-activity-and-grey-matter-volume-change
#12
Song Cao, Bangyong Qin, Yi Zhang, Jie Yuan, Bao Fu, Peng Xie, Ganjun Song, Ying Li, Tian Yu
OBJECTIVE: Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), which is a chronic neuropathic pain (NP). Whether the chronification from HZ to PHN induced brain functional or structural change is unknown and no study compared the changes of the same brains of patients who transited from HZ to PHN. We minimized individual differences and observed whether the chronification of HZ to PHN induces functional and pain duration dependent grey matter volume (GMV) change in HZ-PHN patients...
2018: American Journal of Translational Research
https://www.readbyqxmd.com/read/29420701/cerebellar-functional-connectivity-in-term-and-very-preterm-born-infants
#13
Charlotte S Herzmann, Abraham Z Snyder, Jeanette K Kenley, Cynthia E Rogers, Joshua S Shimony, Christopher D Smyser
Cortical resting state networks have been consistently identified in infants using resting state-functional connectivity magnetic resonance imaging (rs-fMRI). Comparable studies in adults have demonstrated cerebellar components of well-established cerebral networks. However, there has been limited investigation of early cerebellar functional connectivity. We acquired non-sedated rs-fMRI data in the first week of life in 57 healthy, term-born infants and at term-equivalent postmenstrual age in 20 very preterm infants (mean birth gestational age 27 ± 2 weeks) without significant cerebral or cerebellar injury...
February 6, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29410136/pretherapeutic-functional-imaging-allows-prediction-of-head-tremor-arrest-after-thalamotomy-for-essential-tremor-the-role-of-altered-interconnectivity-between-thalamolimbic-and-supplementary-motor-circuits
#14
Constantin Tuleasca, Jean Régis, Elena Najdenovska, Tatiana Witjas, Nadine Girard, Jérôme Champoudry, Mohamed Faouzi, Jean-Philippe Thiran, Meritxell Bach Cuadra, Marc Levivier, Dimitri Van De Ville
OBJECTIVE: To correlate pretherapeutic resting-state functional MRI (rs-fMRI) measures with pretherapeutic head tremor presence and/or further improvement 1 year after stereotactic radiosurgical thalamotomy (SRS-T) for essential tremor (ET). METHODS: We prospectively collected head tremor scores (range 0-3) and rs-fMRI data for a cohort of 17 consecutive ET patients in pretherapeutic and 1 year after SRS-T states. We additionally acquired rs-fMRI data for a healthy control (HC) group (n=12)...
January 31, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29409566/brain-behavior-patterns-define-a-dimensional-biotype-in-medication-na%C3%A3-ve-adults-with-attention-deficit-hyperactivity-disorder
#15
Hsiang-Yuan Lin, Luca Cocchi, Andrew Zalesky, Jinglei Lv, Alistair Perry, Wen-Yih Isaac Tseng, Prantik Kundu, Michael Breakspear, Susan Shur-Fen Gau
BACKGROUND: Childhood-onset attention-deficit hyperactivity disorder (ADHD) in adults is clinically heterogeneous and commonly presents with different patterns of cognitive deficits. It is unclear if this clinical heterogeneity expresses a dimensional or categorical difference in ADHD. METHODS: We first studied differences in functional connectivity in multi-echo resting-state functional magnetic resonance imaging (rs-fMRI) acquired from 80 medication-naïve adults with ADHD and 123 matched healthy controls...
February 7, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29406962/altered-spontaneous-brain-activity-in-mri-negative-refractory-temporal-lobe-epilepsy-patients-with-major-depressive-disorder-a-resting-state-fmri-study
#16
Xi Zhu, Zhongqiong He, Cheng Luo, Xiangmiao Qiu, Shixu He, Anjiao Peng, Lin Zhang, Lei Chen
OBJECTIVE: To investigate alterations in spontaneous brain activity in MRI-negative refractory temporal lobe epilepsy patients with major depressive disorder using resting-state functional magnetic resonance imaging (RS-fMRI). METHODS: Eighteen MRI-negative refractory temporal lobe epilepsy patients with major depressive disorder (PDD), 17 MRI-negative refractory temporal lobe epilepsy patients without major depressive disorder (nPDD), and 21 matched healthy controls (HC) were recruited from West China Hospital of SiChuan University from April 2016 to June 2017...
March 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29403027/human-brain-functional-areas-of-unitary-pooled-activity-discovered-with-fmri
#17
Jie Huang
We report the discovery of human brain functional areas of unitary pooled activity (FAUPAs) using fMRI. A FAUPA is defined as an area in which the temporal variation of the activity is the same across the entire area. This dynamically unitary activity implies a perfect temporal correlation everywhere within the FAUPA for the activity-induced BOLD response, i.e., the corresponding Pearson correlation coefficient (R) is 1 for the BOLD responses of any two locations within the FAUPA. A novel method was developed to identify the FAUPA...
February 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29392456/distinct-manifestation-of-cognitive-deficits-associate-with-different-resting-state-network-disruptions-in-non-demented-patients-with-parkinson-s-disease
#18
Kazuya Kawabata, Hirohisa Watanabe, Kazuhiro Hara, Epifanio Bagarinao, Noritaka Yoneyama, Aya Ogura, Kazunori Imai, Michihito Masuda, Takamasa Yokoi, Reiko Ohdake, Yasuhiro Tanaka, Takashi Tsuboi, Tomohiko Nakamura, Masaaki Hirayama, Mizuki Ito, Naoki Atsuta, Satoshi Maesawa, Shinji Naganawa, Masahisa Katsuno, Gen Sobue
Cognitive deficits in Parkinson's disease (PD) are heterogeneous entities, but a relationship between the heterogeneity of cognitive deficits and resting-state network (RSN) changes remains elusive. In this study, we examined five sub-domain scores according to Addenbrooke's Cognitive Examination-Revised (ACE-R) for the cognitive evaluation and classification of 72 non-demented patients with PD. Twenty-eight patients were classified as PD with normal cognition (PD-NC). The remaining 44 were subdivided into the following 2 groups using a hierarchical cluster analysis: 20 with a predominant decrease in memory (PD with amnestic cognitive deficits: PD-A) and 24 with good memory who exhibited a decrease in other sub-domains (PD with non-amnestic cognitive deficits: PD-NA)...
February 1, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29378319/alter-spontaneous-activity-in-amygdala-and-vmpfc-during-fear-consolidation-following-24%C3%A2-h-sleep-deprivation
#19
Pan Feng, Benjamin Becker, Tingyong Feng, Yong Zheng
Sleep deprivation (SD) has been associated with cognitive and emotional disruptions, however its impact on the acquisition of fear and subsequent fear memory consolidation remain unknown. To address this question, we measured human brain activity before and after fear acquisition under conditions of 24 h sleep deprivation versus normal sleep using resting-state functional magnetic resonance imaging (rs-fMRI). Additionally, we explored whether the fear acquisition-induced change of brain activity during the fear memory consolidation window can be predicted by subjective fear ratings and autonomic fear response, assessed by skin conductance responses (SCR) during acquisition...
January 26, 2018: NeuroImage
https://www.readbyqxmd.com/read/29377435/breakdown-in-the-temporal-and-spatial-organization-of-spontaneous-brain-activity-during-general-anesthesia
#20
Jianfeng Zhang, Zirui Huang, Yali Chen, Jun Zhang, Diana Ghinda, Yuliya Nikolova, Jinsong Wu, Jianghui Xu, Wenjie Bai, Ying Mao, Zhong Yang, Niall Duncan, Pengmin Qin, Hao Wang, Bing Chen, Xuchu Weng, Georg Northoff
Which temporal features that can characterize different brain states (i.e., consciousness or unconsciousness) is a fundamental question in the neuroscience of consciousness. Using resting-state functional magnetic resonance imaging (rs-fMRI), we investigated the spatial patterns of two temporal features: the long-range temporal correlations (LRTCs), measured by power-law exponent (PLE), and temporal variability, measured by standard deviation (SD) during wakefulness and anesthetic-induced unconsciousness. We found that both PLE and SD showed global reductions across the whole brain during anesthetic state comparing to wakefulness...
January 28, 2018: Human Brain Mapping
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