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Thyroid ultrasonography

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https://www.readbyqxmd.com/read/29228030/logistic-regression-analysis-of-conventional-ultrasonography-strain-elastosonography-and-contrast-enhanced-ultrasound-characteristics-for-the-differentiation-of-benign-and-malignant-thyroid-nodules
#1
Tiantian Pang, Leidan Huang, Yingyuan Deng, Tianfu Wang, Siping Chen, Xuehao Gong, Weixiang Liu
The aim of the study is to screen the significant sonographic features by logistic regression analysis and fit a model to diagnose thyroid nodules. A total of 525 pathological thyroid nodules were retrospectively analyzed. All the nodules underwent conventional ultrasonography (US), strain elastosonography (SE), and contrast -enhanced ultrasound (CEUS). Those nodules' 12 suspicious sonographic features were used to assess thyroid nodules. The significant features of diagnosing thyroid nodules were picked out by logistic regression analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29211863/high-serum-tsh-level-is-associated-with-progression-of-papillary-thyroid-microcarcinoma-during-active-surveillance
#2
Hye In Kim, Hye Won Jang, Hyeon Seon Ahn, Soohyun Ahn, So Young Park, Young Lyun Oh, Soo Yeon Hahn, Jung Hee Shin, Jung-Han Kim, Jee Soo Kim, Jae Hoon Chung, Tae Hyuk Kim, Sun Wook Kim
Objective: Thyroid-stimulating hormone (TSH) is a growth factor affecting initiation or progression of papillary thyroid cancer (PTC), which supports TSH suppressive therapy in PTC patients. In patients with papillary thyroid microcarcinoma (PTMC) during active surveillance, however, the association between serum TSH level and growth of PTMC has not been demonstrated. Patients: We analyzed 127 PTMCs in 126 patients under active surveillance with serial serum TSH measurement and ultrasonography...
December 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29196301/interobserver-agreement-of-various-thyroid-imaging-reporting-and-data-systems
#3
Giorgio Grani, Livia Lamartina, Vito Cantisani, Marianna Maranghi, Piernatale Lucia, Cosimo Durante
Ultrasonography is the best available tool for the initial work-up of thyroid nodules. Substantial interobserver variability has been documented in the recognition and reporting of some of the lesion characteristics. A number of classification systems have been developed to estimate the likelihood of malignancy: several of them have been endorsed by scientific societies, but their reproducibility has yet to be assessed. We evaluated the interobserver variability of the AACE/ACE/AME, ACR, ATA, EU-TIRADS, and K-TIRADS classification systems and the interobserver concordance in the indication to FNA biopsy...
December 1, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29183524/the-place-of-elastography-in-evaluating-the-efficacy-of-radiofrequency-ablation-of-thyroid-nodules
#4
Ufuk O Idiz, Erhan Aysan, Leyla Elmas, Seyma Yildiz, Huseyin Akbulut
The usage of radiofrequency ablation (RFA) therapy and elastography to treat thyroid nodules has been increasing recently. Elastography specifically measures the stiffness of tissue using ultrasonography (US). The aim of the present study was to evaluate the relationship between the elastography values of thyroid nodules and the efficacy of RFA therapy. Ultrasonography was performed on 49 patients who had a thyroid nodule with a diameter of 1 cm or greater before RFA therapy. The RFA was performed under local anesthesia, and elastography was used to measure the stiffness of the normal thyroid tissue, sternocleidomastoid muscle (SCM) and thyroid nodules three months after RFA...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29181988/diagnostic-performances-and-interobserver-agreement-according-to-observer-experience-a-comparison-study-using-three-guidelines-for-management-of-thyroid-nodules
#5
Jieun Koh, Soo-Yeon Kim, Hye Sun Lee, Eun-Kyung Kim, Jin Young Kwak, Hee Jung Moon, Jung Hyun Yoon
Background The differences regarding categorization of thyroid nodules among different guidelines may affect the diagnostic performances and agreement among observers. Purpose To compare the diagnostic performances and agreements between observers with various degree of experience when applying different guidelines for stratifying thyroid nodules using suspicious ultrasonography (US) features. Material and Methods This retrospective study included 370 thyroid nodules (≥10 mm). Four observers, grouped as experienced and inexperienced, evaluated the US features and made final assessments according to the Kim criteria, Thyroid Imaging Reporting and Data System (TIRADS) by Kwak et al...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29179642/a-follow-up-strategy-for-patients-with-excellent-response-to-initial-therapy-for-differentiated-thyroid-carcinoma-less-is-better
#6
MinJi Jeon, Mijin Kim, Suyeon Park, Hye-Seon Oh, Tae Yong Kim, Won Bae Kim, YoungKee Shong, Won Gu Kim
BACKGROUND: The risk of recurrence in patients with differentiated thyroid cancer (DTC) can be estimated based on their response to initial therapy. The aim of this study is to evaluate adequate follow-up strategy for DTC patients with excellent response by assessing the characteristics of structural recurrence. METHODS: This historical cohort study included 1359 DTC patients who had excellent response to initial therapy after total thyroidectomy with radioactive iodine remnant ablation...
November 27, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29178507/is-doppler-ultrasonography-of-value-for-the-differentiation-between-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-and-invasive-encapsulated-follicular-variant-of-papillary-thyroid-carcinoma-iefvptc
#7
Pedro Weslley Rosario
Recently, the noninvasive encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) received the name "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) and was no longer considered "cancer".1 Furthermore, the treatment recommendations for differentiated thyroid cancer no longer apply to NIFTP, which is sufficiently treated by lobectomy only.1 The probability that a thyroid nodule corresponds to NIFTP has become of great interest in clinical practice, since it would at least influence the extent of surgery...
November 25, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29173938/evaluation-of-incidental-thyroid-nodules-in-cancer-patients
#8
Güven Barış Cansu, Nusret Yılmaz, Serap Toru, Ramazan Sarı, Güzide Gökhan Ocak, Cumhur Arıcı, Hasan Ali Altunbaş, Mustafa Kemal Balcı
OBJECTIVE: Frequency of thyroid cancer in incidental thyroid nodules identified by imaging techniques in cancer patients is higher than that in the normal population. In the retrospective study, we have both investigated the incidence of thyroid cancer in incidentally identified nodules and compared the imaging techniques to determine whether there is any difference between them in detection of malign nodules. METHODS: A total of 7319 patients who underwent thyroid fine-needle aspiration biopsy (FNAB) were included in the study...
January 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29145557/comparative-analysis-of-the-growth-pattern-of-thyroid-cancer-in-young-patients-screened-by-ultrasonography-in-japan-after-a-nuclear-accident-the-fukushima-health-management-survey
#9
Sanae Midorikawa, Akira Ohtsuru, Michio Murakami, Hideto Takahashi, Satoru Suzuki, Takashi Matsuzuka, Hiroki Shimura, Tetsuya Ohira, Shin-Ichi Suzuki, Seiji Yasumura, Shunichi Yamashita, Hitoshi Ohto, Koichi Tanigawa, Kenji Kamiya
Importance: Thyroid cancer generally grows at a very slow rate in adults, and overdiagnosis is a global issue. However, the detection of early-stage thyroid cancer by screening is not well described in young patients. To prevent overdiagnosis, it is essential to understand the natural course of thyroid cancer growth detection by ultrasonography screening in young patients. Objective: To evaluate the natural progression of thyroid cancer in young patients. Design, Setting, and Participants: An observational study evaluated changes in the diameter of malignant or suspected malignant thyroid tumors on 2 occasions...
November 16, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29142854/skin-metastasis-on-the-neck-an-unusual-presentation-of-recurrence-of-papillary-thyroid-carcinoma
#10
Selen Soylu, Akif Enes Arikan, Serkan Teksoz, Murat Ozcan, Yusuf Bukey
Skin metastasis of papillary thyroid carcinoma (PTC) is rare. Here, two cases of skin metastases of PTC are presented. Both of the patients were females, one is 83 and the other is 65 years old. The patients were admitted to the hospital with a movable skin lesion on anterior neck region. Free T3 and T4 levels were in normal levels and TSH levels were low in both patients. The 83-year-old patient underwent total thyroidectomy due to papillary thyroid cancer and received (131)I ablation therapy and then thyroid suppression therapy...
October 2017: Gland Surgery
https://www.readbyqxmd.com/read/29137452/pathologic-basis-of-the-sonographic-differences-between-thyroid-cancer-and-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#11
Grace C H Yang, Karen O Fried
Ultrasonography is pivotal in triage thyroid biopsy in the era after the identification of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). This pictorial essay illustrates the pathologic basis of the sonographic features that distinguish NIFTP from thyroid cancers. In this study, we present the correlations of ultrasonography to ×1 histopathology to assess shape and margin characteristics. Markedly hypoechoic nodules correlate to microfollicular/solid nodules, while isoechoic/hyperechoic thyroid nodules correlate to normofollicular/macrofollicular nodules...
August 19, 2017: Ultrasonography
https://www.readbyqxmd.com/read/29137384/mir-324-5p-assists-ultrasonography-in-predicting-lymph-node-metastasis-of-unifocal-papillary-thyroid-microcarcinoma-without-extracapsular-spread
#12
Yanhua Yang, Shujun Xia, Xiaofeng Ni, Zhongxin Ni, Lu Zhang, Wenhan Wang, Yanjun Kong, Yan Wang, Lei Ye, Weiwei Zhan
Ultrasonography is the first choice of lymph node metastasis (LNM) detection which is crucial for therapeutic options of papillary thyroid cancer (PTC). However, the sensitivity of ultrasonography in detecting LNM of PTC is relatively low; especially in central LNM. MiR-324-5p has been reported to play important roles in the metastasis of various cancers. To explore the relationship between miR-324-5p and LNM in PTC, quantitative real-time polymerase chain reaction was performed in PTC tissue and fine needle aspiration (FNA) washout successively...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29136676/papillary-thyroid-cancer-and-coexisting-autoimmune-thyroiditis
#13
Franziska Veit, Dieter Graf, Saskia Momberger, Brigitte Helmich-Kapp, Ilka Ruschenburg, Anja Peters, Jochen Kussmann, Wolfgang Saeger, Kurt Werner Schmidt, Martin Toetsch, Kai Nestler, Klaus Mann
Histological findings often display an association between papillary thyroid carcinomas (PTC) and autoimmune thyroiditis (AIT) and so differ significantly from follicular thyroid carcinomas (FTC). The aim of this interdisciplinary, retrospective study was to evaluate the association of AIT in patients with PTC and FTC and a control group of benign nodular goiters. One hundred thyroidectomies with histologically confirmed differentiated thyroid carcinomas, 67 with PTC and 33 with FTC, were submitted for examination...
November 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29128184/importance-of-surgeon-performed-ultrasound-in-the-preoperative-nodal-assessment-of-patients-with-potential-thyroid-malignancy
#14
Rosebel Monteiro, Amy Han, Muhammad Etiwy, Andrew Swearingen, Vikram Krishnamurthy, Judy Jin, Joyce J Shin, Eren Berber, Allan E Siperstein
INTRODUCTION: A comprehensive cervical ultrasound evaluation is essential in the operative planning of patients with thyroid disease. Reliance on radiographic reports alone may result in incomplete operative management as pathologic lymph nodes are often not palpable and evaluation of the lateral neck is not routine. This study examined the role of surgeon-performed ultrasound in the evaluation of patients who underwent lateral neck dissection for thyroid cancer. METHODS: We conducted a retrospective review of a prospectively maintained database of patients who underwent therapeutic lymph node dissection for thyroid cancer between 2001 and 2016 at our tertiary referral center...
November 8, 2017: Surgery
https://www.readbyqxmd.com/read/29128176/back-so-soon-is-early-recurrence-of-papillary-thyroid-cancer-really-just-persistent-disease
#15
Maria F Bates, Marcos R Lamas, Reese W Randle, Kristin L Long, Susan C Pitt, David F Schneider, Rebecca S Sippel
BACKGROUND: Papillary thyroid carcinoma has excellent survival, yet recurrence remains a challenge. We sought to determine the proportion of reoperations performed for persistent, rather than truly recurrent, disease. METHODS: We conducted a retrospective review of a prospectively maintained database. Patients with papillary thyroid carcinoma who underwent reoperation for disease from 2000-2016 were included. We defined recurrence as disease that developed after a patient had an undetectable thyroglobulin and a negative ultrasonography within 1 year of operation...
November 8, 2017: Surgery
https://www.readbyqxmd.com/read/29127763/thyroid-evaluation-of-children-and-adolescents-with-williams-syndrome-in-zhejiang-province
#16
Wei-Jun Chen, Chai Ji, Dan Yao, Zheng-Yan Zhao
BACKGROUND: The objective of the study was to describe the prevalence of abnormal thyroid function and volume in children and adolescents with Williams syndrome (WS) in Zhejiang Province, China. METHODS: Thyroid function, including thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and thyroid antibodies (thyroid peroxidase and thyroglobulin) were measured in 83 patients with WS, aged 0.2-16.5 years. Twenty-three patients were followed for an average of 1...
November 11, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29121688/long-term-follow-up-in-patients-with-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-without-a-suspicion-of-persistent-disease-in-postoperative-assessment
#17
Pedro Weslley Rosario, Gabriela Franco Mourão, Luís Fernando Faria Oliveira, Maria Regina Calsolari
The objective was to determine whether negative assessment after surgery is a predictor of no relevant change of the results in subsequent evaluations in patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Six months after surgery, "absence of persistent disease" was defined when concentration of thyroglobulin (Tg) is ≤2 ng/ml in patients undergoing total thyroidectomy and ≤10 ng/ml in those undergoing lobectomy, in the absence of antithyroglobulin antibodies (TgAb), and neck ultrasonography (US) without abnormalities...
November 9, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29108488/validation-of-three-scoring-risk-stratification-models-for-thyroid-nodules
#18
Su Min Ha, Hye Shin Ahn, Jung Hwan Baek, Hwa Young Ahn, Yun Jae Chung, Bo Youn Cho, Sung Bin Park
BACKGROUND: To minimize potential harm from overuse of fine-needle aspiration, Thyroid Imaging Reporting and Data Systems (TIRADSs) were developed for thyroid nodule risk stratification. The purpose of this study was to perform validation of three scoring risk stratification models for thyroid nodules using ultrasonography features, a web-based malignancy risk stratification system at website (http://www.gap.pe.kr/thyroidnodule.php) and those developed by the Korean Society of Thyroid Radiology (KSThR) and the American College of Radiology (ACR)...
November 6, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29104644/contrast-enhanced-ultrasonography-features-of-papillary-thyroid-carcinoma-for-predicting-cervical-lymph-node-metastasis
#19
Ying Liu, Hong Zhou, Peng Yang, Yang Zhou, Jian Wu, Changyu Chen, Ming Ye, Jing Luo
The present study was performed to evaluate the predictive value of contrast-enhanced ultrasonography (CEUS) for the risk of cervical lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC). Between May 2014 and November 2016, 42 patients who received surgery for suspicious PTCs were enrolled in the present study. Each individual underwent CEUS with conventional ultrasound (US), preoperative US-guided fine needle aspiration and personalized surgery. Subsequently, the microvascular density (MVD) of all surgical specimens was measured...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29096966/evaluation-of-the-thyroid-nodule-with-high-resolution-ultrasonography-and-elastography-without-fine-needle-aspiration-biopsy
#20
Antonio Ríos, José Manuel Rodríguez, Nuria María Torregrosa, Begoña Torregrosa, Angela Cepero, María Dolores Abellán, Antonio Miguel Hernández, Pascual Parrilla
INTRODUCTION: Fine needle aspiration biopsy (FNAB) is the gold standard screening technique used in the diagnostic protocol for thyroid nodules. However, it is not free of complications. OBJECTIVE: To identify thyroid nodules in which FNAB could be avoided during the diagnostic process by means of the use of a high-resolution ultrasonography or elastography. MATERIAL AND METHOD: A prospective, non-randomized study was carried out. Single thyroid nodules and dominant nodules of multinodular goiter were included...
October 30, 2017: Medicina Clínica
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