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Thyroid ultrasonography

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https://www.readbyqxmd.com/read/28101352/shear-wave-elastography-and-contrast-enhanced-ultrasonography-in-the-diagnosis-of-thyroid-malignant-nodules
#1
Mei Chen, Ke-Qin Zhang, You-Feng Xu, Sheng-Min Zhang, Yong Cao, Wei-Qun Sun
The aim of the present study was to evaluate the value of shear wave elastography (SWE) and contrast-enhanced ultrasonography (CEUS) in the diagnosis of thyroid malignant nodules. A total of 253 patients with 319 thyroid nodules were subjected to two-dimensional ultrasound (2DUS) and CEUS examinations prior to thyroidectomy between March, 2014 and December, 2015. Young's modulus value for each nodule on 2DUS and CEUS images were recorded. The sensitivity, specificity and accuracy of 2DUS, SWE and CEUS in the diagnosis of thyroid malignant nodules were assessed...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28058547/effect-of-thyroid-remnant-volume-on-the-risk-of-hypothyroidism-after-hemithyroidectomy-a-prospective-study
#2
Brian Hung-Hin Lang, Carlos K H Wong, Kai Pun Wong, Kelvin Ka-Wan Chu, Tony W H Shek
BACKGROUND: Hypothyroidism is a common sequel after a hemithyroidectomy. Although various risk factors leading to hypothyroidism have been reported, the effect of the contralateral lobe's volume has been understudied. This study aimed to examine the association between the preoperative contralateral lobe's volume and the risk of postoperative hypothyroidism. METHODS: During a 2-year period, 150 eligible patients undergoing a hemithyroidectomy were evaluated. The volume of the contralateral nonexcised lobe was estimated preoperatively by independent assessors on ultrasonography using the following formula: width (in cm) × depth (in cm) × length (in cm) × (π/6), adjusted for the body surface area (BSA)...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28054188/predictive-factors-for-active-surveillance-of-subcentimeter-thyroid-nodules-with-highly-suspicious-us-features
#3
Hye Mi Gweon, Eun Ju Son, Jeong-Ah Kim, Ji Hyun Youk
PURPOSE: This study was designed to assess the outcomes of subcentimeter thyroid nodules with highly suspicious ultrasonography (US) features and to investigate the predictive factors associated with malignancy and aggressive biological behavior to determine appropriate candidate factors for active surveillance. METHODS: Between June 2011 and December 2013, 1866 subcentimeter thyroid nodules with highly suspicious US features that were subjected to US-guided fine needle aspiration and subsequent surgery or US follow-up of at least 2 years were evaluated...
January 4, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28052656/the-prognostic-values-of-preoperative-tumor-volume-and-tumor-diameter-in-t1n0-papillary-thyroid-cancer
#4
Seung Taek Lim, Ye Won Jeon, Young Jin Suh
Purpose: The current TNM staging system for papillary thyroid cancer (PTC), which is based on tumor diameter, may not precisely reflect the true tumor burden. Therefore, we investigated whether preoperative tumor volume might more accurately reflect tumor burden and predict prognosis in patients with T1N0 PTC than preoperative tumor diameter. Materials and Methods: We retrospectively reviewed data from 1,659 patients with T1N0 PTC, and after exclusion, a total of 1,081 patients were ultimately included...
December 13, 2016: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28041586/thyroid-nodules-%C3%AE-guide-to-assessment-treatment-and-follow-up
#5
REVIEW
Stavroula Α Paschou, Andromachi Vryonidou, Dimitrios G Goulis
Thyroid nodules constitute by far the most common disorder of the endocrine system. Epidemiological studies have indicated that approximately 5% of women and 1% of men resident in iodine-sufficient areas have palpable thyroid nodules. However, by the age of 60 years about 50% of the general population is estimated to have at least one thyroid nodule. Indeed, the reported prevalence of a "thyroid incidentaloma" is up to 70% when neck/carotid artery ultrasound, computed tomography (CT) or magnetic resonance imaging (MRI) is performed for other indications...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28033216/incremental-value-of-18f-fluorocholine-pet-ct-in-the-localization-of-double-parathyroid-adenomas
#6
Paul Lalire, Sang Ly, Sophie Deguelte, Martine Patey, David Morland
A 73-year-old man displaying primary hyperparathyroidism with severe hypercalcemia (Ca: 4.1 mmol/l, PTH > 600 pmol/l) was referred for preoperative localization of a parathyroid adenoma. Tc-pertechnetate and Tc-sestaMIBI dual tracer scintigraphy displayed a mild focal uptake in the projection of the right thyroid lobe with negative ultrasonography. F-Fluorocholine PET/CT was quickly performed considering this discrepancy and not only confirmed the scintigraphic findings but also revealed a second contralateral focus of increased uptake, both later confirmed by operative consideration (the two other parathyroid glands are considered normal by the surgeon), pathology, and intraoperative parathyroid hormone assessment...
December 28, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28029495/an-algorithm-of-image-heterogeneity-with-contrast-enhanced-ultrasound-in-differential-diagnosis-of-solid-thyroid-nodules
#7
Lifang Jin, Changsong Xu, Xueqian Xie, Fan Li, Xiuhong Lv, Lianfang Du
Enhancement heterogeneity on contrast-enhanced ultrasonography (CEUS) is used to differentiate between benign and malignant thyroid nodules. In this study, we used an algorithm to quantify enhancement heterogeneity of solid thyroid nodules on CEUS. The heterogeneity value (HV) is calculated as standard deviation/mean intensity × 100 (using Adobe Photoshop). The heterogeneity ratio (HR) is calculated as the ratio of the HV of the nodule to that of the surrounding parenchyma. Three phases-ascending, peak and descending phases-were studied...
October 28, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28028343/cribriform-morular-variant-of-papillary-thyroid-carcinoma-cytomorphology-differential-diagnosis-and-diagnostic-implications-in-patients-with-adenomatous-polyposis-coli
#8
Amarathunga Ah Priyani, Shamika T Opatha, Nisayuri W Gunathilake, Menaka Ds Lokuhetty
Cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC), which has a better prognosis, is seen mostly in the setting of familial adenomatous polyposis (FAP). The cytomorphology of CMV-PTC is diverse; hence, it could be mistaken for other thyroid neoplasms with bad prognostic outcome. This case is of a 24-year-old female diagnosed with polyposis coli found to have thyroid nodules at screening ultrasonography. Aspirated thyroid smears were hypercellular with epithelial cells arranged in monolayer sheets, papillae with discohesion, and spindling of cells at the edges, cribriform clusters, and cell morules...
October 2016: Journal of Cytology
https://www.readbyqxmd.com/read/28028337/thyroid-fnac-containing-h%C3%A3-rthle-cells-and-h%C3%A3-rthle-like-cells-a-study-of-128-cases
#9
Aylin Yazgan, Serdar Balci, Nazmiye Dincer, Pamir Eren Ersoy, Dilek Tuzun, Reyhan Ersoy, Cigdem Irkkan, Bekir Cakir, Gulnur Guler
AIM: It is a diagnostic challenge to differentiate benign and malignant cytology in the presence of Hürthle cells. In our previous study, it was determined that in fine needle aspirations (FNA), the malignancy outcome of the Hürthle cells containing group tend to be papillary thyroid carcinoma (PTC) in a higher percentage. The most common misinterpretation is caused by PTC cells with large cytoplasm-like Hürthle cells. The aim of this study is to predict histologic outcome of the nodules, which have Hürthle cells in FNA according to cytological, clinical features, and BRAF(V600E) mutation status...
October 2016: Journal of Cytology
https://www.readbyqxmd.com/read/27994903/congenital-hypothyroidism-an-unusual-combination-of-biochemical-abnormalities
#10
Ruchi Mantri, S B Bavdekar, Sushma U Save
A forty-five-day-old female infant presented with prolonged jaundice with clinical features suggestive of congenital hypothyroidism (CHT). On investigations, the infant was noted to have indirect hyperbilirubinemia (13.8 mg/dl) with increased levels of AST (298 IU/dl) and ALT (174 IU/dl) in the serum. The child had low levels of free T3 (<1 pg/ml) and free T4 (0.4 ng/dl) secondary to thyroid agenesis detected on radionuclide scan and ultrasonography of the neck and raised levels of TSH (>500 microIU/ml) in the serum...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27975148/complications-encountered-in-ultrasonography-guided-radiofrequency-ablation-of-benign-thyroid-nodules-and-recurrent-thyroid-cancers
#11
Cherry Kim, Jeong Hyun Lee, Young Jun Choi, Won Bae Kim, Tae Yon Sung, Jung Hwan Baek
OBJECTIVES: To evaluate the complication rates and describe the possible complications of ultrasonography-guided radiofrequency ablation (RFA) of benign thyroid nodules (BTN) and recurrent thyroid cancers (RTC), and to compare the complication rates between BTN and RTC. METHODS: This retrospective study reviewed 875 patients who underwent RFA for BTN (746 patients; 83.5%) or RTC (129 patients; 14.7%). Medical records were reviewed for all types of complications occurring during and after the RFA procedure...
December 14, 2016: European Radiology
https://www.readbyqxmd.com/read/27956733/metastatic-renal-cell-carcinoma-in-the-thyroid-gland-ultrasonographic-features-and-the-diagnostic-role-of-core-needle-biopsy
#12
Ok Kyu Song, Ja Seung Koo, Jin Young Kwak, Hee Jung Moon, Jung Hyun Yoon, Eun-Kyung Kim
Purpose: The aims of this study were to present the ultrasonographic (US) features of metastatic renal cell carcinoma (RCC) in the thyroid gland and to evaluate the diagnostic utility of fineneedle aspiration (FNA) and core needle biopsy (CNB). Methods: Eight patients with nine metastatic RCC nodules in the thyroid glands who were treated from January 2002 to March 2015 in a single tertiary hospital were consecutively selected and retrospectively reviewed. US features and clinical history were obtained from the institution's medical database...
November 9, 2016: Ultrasonography
https://www.readbyqxmd.com/read/27939854/bayesian-analysis-of-high-resolution-ultrasonography-and-guided-fine-needle-aspiration-cytology-in-diagnosis-of-palpable-thyroid-nodules
#13
Niranjan Sahu, Rabindra Nath Padhy
INTRODUCTION: To evaluate diagnostic accuracy of high-resolution ultrasonography in differentiation of benign and malignant thyroid nodules in comparison to results of guided fine needle aspiration cytology based on the Bayes rule. OBJECTIVE: To assess the validity of ultrasonography results of thyroid nodules in comparison to guided fine needle aspiration cytology findings. METHODS: This study was done on randomly chosen 80 patients presented with palpable thyroid nodules, undergone real-time sonographic evaluation of thyroid nodules to characterize features, internal consistency, margins, echotexture, calcification, peripheral lucent halo and vascularity...
November 17, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27936530/endocrinology-update-thyroid-disorders
#14
Scott Kelley
Thyroid disease affects nearly every organ system in the body. Hypothyroidism is a state of thyroid hormone insufficiency that results in decreased metabolism and secondary effects including fatigue and weight gain. Primary hypothyroidism typically is a result of autoimmune thyroiditis or iodine deficiency and is assessed by measurement of the thyroid-stimulating hormone (TSH) level. This level usually is elevated in patients with hypothyroidism and low in patients with hyperthyroidism. Levothyroxine is the treatment of choice for hypothyroidism...
December 2016: FP Essentials
https://www.readbyqxmd.com/read/27931904/effect-of-lithium-on-thyroid-function-in-adolescents-with-mood-disorder
#15
Rati Ranjan Sethy, Vinod Kumar Sinha
BACKGROUND: The purpose of the study was to determine thyroid gland volume and the frequency of thyroid dysfunction by using ultrasonography and laboratory parameters (TSH, T3, and T4) in long term lithium treated adolescent patients with mood disorder. METHODOLOGY: In a cross-sectional study, we performed ultrasonography and thyroid function test in 30 adolescent patients on long-term lithium treatment for mood disorder. Patients with adequate serum lithium levels for one year or more were taken for the study...
December 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27925648/sonographic-evaluation-of-intrathyroid-metastases
#16
J Matthew Debnam, Michael Kwon, Bruno D Fornage, Savitri Krishnamurthy, Gary L Clayman, Beth S Edeiken-Monroe
OBJECTIVES: Intrathyroid metastases from extrathyroid primary tumors are rare. Clinical findings may be subtle, but detection of intrathyroid metastases has improved with sonography. The objective of this study was to evaluate the sonographic appearance of intrathyroid metastases. METHODS: Patients with thyroid masses with cytopathologic features matching those of an extrathyroid primary tumor were retrospectively identified. The appearances of intrathyroid metastases on sonography were reviewed for the following features: size, margin regularity, echogenicity, echotexture, vascularity on power or color Doppler ultrasonography, and the presence or absence of any associated cervical adenopathy...
January 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27924514/clinical-and-sonographic-assessment-of-cervical-lymph-node-metastasis-in-papillary-thyroid-carcinoma
#17
Qi Wu, Yi-Min Zhang, Si Sun, Juan-Juan Li, Juan Wu, Xiang Li, Shan Zhu, Wen Wei, Sheng-Rong Sun
The purpose of this study was to assess the differences in clinical and sonographic features of papillary thyroid carcinoma (PTC) between cervical lymph node metastatic (CLNM) and nonmetastatic groups. Clinical data of PTC patients (414 patients with 624 malignant nodules) who underwent a preoperative ultrasonography and surgery between June 2010 and March 2015 at Renmin Hospital of Wuhan University were retrospectively analyzed. Clinical factors, preoperative ultrasound features and the final pathological findings were obtained...
December 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27911001/diagnostic-accuracy-of-thyroid-imaging-reporting-and-data-system-in-the-prediction-of-malignancy-in-nodules-with-atypia-and-follicular-lesion-of-undetermined-significance-cytologies
#18
Husniye Baser, Bekir Cakir, Oya Topaloglu, Afra Alkan, Sefika Burcak Polat, Hayriye Tatli Dogan, Mustafa Omer Yazicioğlu, Cevdet Aydin, Reyhan Ersoy
OBJECTIVE: Thyroid Imaging Reporting and Data System (TIRADS) is a simple and reliable reporting system for the prediction of malignancy. We aimed to determine the role of TIRADS in the prediction of malignancy in subcategories of Bethesda Category III, atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS). DESIGN & PATIENTS: A total of 461 nodules with AUS cytology in 450 patients and 179 nodules with FLUS cytology in 168 patients were included...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27906682/nonhsat076754-aids-ultrasonography-in-predicting-lymph-node-metastasis-and-promotes-migration-and-invasion-of-papillary-thyroid-cancer-cells
#19
Shujun Xia, Chuandong Wang, Xiaofeng Ni, Zhongxin Ni, Yijie Dong, Weiwei Zhan
Lymph node metastasis (LNM) is the primary challenge in papillary thyroid cancer (PTC). Recurrent cancerous lymph nodes require repeated surgeries, which increases the risk for surgical complications. Thus, the evaluation of LNM before surgery is important. Ultrasonography is the most convenient way to examine cervical LNM, but the sensitivity of ultrasonography in the identification of LNM in cases of PTC is extremely low. A series of lncRNAs (long noncoding RNAs) have been reported as candidate biomarkers in a variety of tumors...
November 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/27901180/ultrasonographic-assessment-of-thyroid-volume-in-oldest-old-individuals
#20
Glaucia Cruzes Duarte, Lara Miguel Quirino Araujo, Felix Magalhães, Clineu Mello Almada, Maysa Seabra Cendoroglo
Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged ≥ 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography...
November 24, 2016: Archives of Endocrinology and Metabolism
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